WP_FIBRIN_COMPLEMENT_RECEPTOR_3_SIGNALING_PATHWAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | FGG | Fibrinogen gamma chain | [1] | -1.28[2] | -0.56[3] | -0.89[4] | -7.01[5] | -9.17[6] | -0.67[7] |
2 | FGA | Fibrinogen alpha chain | [8] | -0.94[9] | -0.81[10] | -0.78[11] | -6.23[12] | -9.19[13] | 0.00[14] |
3 | FGB | Fibrinogen beta chain | [15] | -2.15[16] | -1.58[17] | 0.21[18] | -4.35[19] | -7.82[20] | 0.78[21] |
4 | LBP | Lipopolysaccharide-binding protein | [22] | -6.34[23] | -9.62[24] | -2.62[25] | -6.86[26] | -12.32[27] | -0.04[28] |
5 | PLG | Plasminogen | [29] | -6.44[30] | -4.58[31] | 2.36[32] | -5.91[33] | -4.51[34] | 0.58[35] |
6 | RHOA | Transforming protein RhoA | [36] | 4.38[37] | 3.63[38] | 3.26[39] | 5.05[40] | 5.23[41] | -1.43[42] |
7 | CD14 | Monocyte differentiation antigen CD14 | [43] | -3.02[44] | -3.35[45] | -1.12[46] | 1.47[47] | 0.01[48] | -0.62[49] |
8 | AKT1 | RAC-alpha serine/threonine-protein kinase | [50] | 5.40[51] | 4.91[52] | 3.25[53] | 6.22[54] | 5.97[55] | -0.35[56] |
9 | IKBKG | NF-kappa-B essential modulator | [57] | 4.43[58] | 4.32[59] | 1.49[60] | 5.42[61] | 3.94[62] | -0.71[63] |
10 | IRAK1 | Interleukin-1 receptor-associated kinase 1 | [64] | 6.73[65] | 5.87[66] | 4.27[67] | 7.07[68] | 7.17[69] | -0.80[70] |
11 | RELA | Transcription factor p65 | [71] | 5.45[72] | 4.69[73] | 4.24[74] | 6.21[75] | 5.85[76] | -0.99[77] |
12 | MYD88 | Myeloid differentiation primary response protein MyD88 | [78] | 5.13[79] | 4.94[80] | 3.78[81] | 5.23[82] | 5.26[83] | 0.69[84] |
13 | TYROBP | TYRO protein tyrosine kinase-binding protein | [85] | -4.64[86] | [87] | [88] | -2.78[89] | [90] | -1.77[91] |
14 | CCL2 | C-C motif chemokine 2 | [92] | -8.08[93] | [94] | -8.34[95] | 2.15[96] | 4.05[97] | -3.80[98] |
15 | IRF3 | Interferon regulatory factor 3 | [99] | 5.61[100] | 5.53[101] | 5.67[102] | 6.62[103] | 5.95[104] | -1.29[105] |
16 | IRAK2 | Interleukin-1 receptor-associated kinase-like 2 | [106] | 5.24[107] | 5.09[108] | 4.28[109] | 3.84[110] | 5.12[111] | -1.13[112] |
17 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [113] | 5.98[114] | 5.41[115] | 4.61[116] | 6.02[117] | 6.66[118] | 0.34[119] |
18 | TICAM1 | TIR domain-containing adapter molecule 1 | [120] | 4.60[121] | 3.25[122] | 3.60[123] | 5.05[124] | 5.82[125] | -0.61[126] |
19 | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha | [127] | 6.22[128] | 7.19[129] | 6.56[130] | 6.92[131] | 7.46[132] | 1.41[133] |
20 | CXCL3 | C-X-C motif chemokine 3 | [134] | 0.49[135] | -2.03[136] | 0.66[137] | 1.81[138] | 5.00[139] | -5.72[140] |
21 | SRC | Proto-oncogene tyrosine-protein kinase Src | [141] | 8.34[142] | 8.07[143] | 6.48[144] | 8.67[145] | 7.58[146] | -0.96[147] |
22 | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta | [148] | 5.84[149] | 5.64[150] | 5.16[151] | 6.53[152] | 6.35[153] | 1.07[154] |
23 | ITGB2 | Integrin beta-2 | [155] | 6.61[156] | 7.75[157] | -1.13[158] | 1.08[159] | -1.17[160] | 1.21[161] |
24 | LY96 | Lymphocyte antigen 96 | [162] | 2.66[163] | 2.02[164] | -4.98[165] | 4.91[166] | 1.02[167] | -1.47[168] |
25 | TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein | [169] | 5.18[170] | 4.89[171] | 4.41[172] | 6.55[173] | 5.11[174] | 0.16[175] |
26 | CBLB | E3 ubiquitin-protein ligase CBL-B | [176] | 4.67[177] | 5.66[178] | 5.50[179] | 7.05[180] | 7.64[181] | 1.26[182] |
27 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 4.94[183] | 6.32[184] | 5.92[185] | 7.40[186] | 7.33[187] | 1.80[188] | |
28 | RASSF5 | Ras association domain-containing protein 5 | [189] | 6.04[190] | 1.13[191] | 5.17[192] | 7.62[193] | 6.47[194] | 1.16[195] |
29 | CXCL10 | C-X-C motif chemokine 10 | [196] | -3.83[197] | -1.77[198] | 2.76[199] | 4.71[200] | -3.15[201] | -2.49[202] |
30 | IRAK4 | Interleukin-1 receptor-associated kinase 4 | [203] | 5.57[204] | 6.68[205] | 6.38[206] | 7.69[207] | 7.18[208] | 1.67[209] |
31 | IL6 | Interleukin-6 | [210] | -3.13[211] | [212] | -0.36[213] | 5.41[214] | 7.66[215] | [216] |
32 | TLR3 | Toll-like receptor 3 | [217] | 1.47[218] | 0.76[219] | -0.15[220] | 5.90[221] | 6.72[222] | 0.94[223] |
33 | TRAF6 | TNF receptor-associated factor 6 | [224] | 6.41[225] | 6.04[226] | 6.02[227] | 7.93[228] | 7.12[229] | 2.80[230] |
34 | NOS2 | Nitric oxide synthase, inducible | [231] | 5.33[232] | [233] | -1.75[234] | 1.41[235] | 0.26[236] | -7.42[237] |
35 | TLR4 | Toll-like receptor 4 | [238] | 5.59[239] | 0.18[240] | -1.29[241] | 1.17[242] | 11.32[243] | 4.36[244] |
36 | REL | Proto-oncogene c-Rel | [245] | 4.80[246] | 6.31[247] | 5.66[248] | 6.42[249] | 6.30[250] | 2.24[251] |
37 | TICAM2 | TIR domain-containing adapter molecule 2 | [252] | -2.56[253] | [254] | -2.82[255] | 4.78[256] | 4.85[257] | -2.09[258] |
38 | ITGAM | Integrin alpha-M | [259] | 2.92[260] | 0.12[261] | 0.75[262] | 3.68[263] | 0.99[264] | 2.80[265] |
39 | SYK | Tyrosine-protein kinase SYK | [266] | -2.85[267] | 2.77[268] | -0.83[269] | 6.37[270] | 2.59[271] | 3.25[272] |
40 | TNF | Tumor necrosis factor | [273] | 6.42[274] | 4.03[275] | -1.16[276] | 4.05[277] | 0.56[278] | -2.00[279] |
41 | PLAT | Tissue-type plasminogen activator | [280] | 7.02[281] | 7.38[282] | 3.92[283] | 11.08[284] | 11.05[285] | 3.45[286] |
42 | IL12B | Interleukin-12 subunit beta | [287] | [288] | [289] | [290] | [291] | [292] | [293] |
43 | MIR718 | [294] | [295] | [296] | [297] | [298] | [299] | [300] | |
44 | IFNB1 | Interferon beta | [301] | [302] | [303] | [304] | [305] | [306] | [307] |