WP_FAS_LIGAND_PATHWAY_AND_STRESS_INDUCTION_OF_HEAT_SHOCK_PROTEINS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | ACTB | Actin, cytoplasmic 1 | [1] | -0.79[2] | -0.79[3] | -0.49[4] | -0.37[5] | -0.59[6] | -0.04[7] |
2 | ACTG1 | Actin, cytoplasmic 2 | [8] | 0.49[9] | -0.15[10] | -0.38[11] | -0.56[12] | -0.01[13] | -0.79[14] |
3 | HSPB1 | Heat shock protein beta-1 | [15] | -2.89[16] | -3.03[17] | -2.60[18] | -0.77[19] | -2.78[20] | -2.66[21] |
4 | LMNA | Prelamin-A/C | [22] | 0.47[23] | 0.59[24] | -1.11[25] | 1.15[26] | 0.53[27] | 0.18[28] |
5 | JUN | Transcription factor AP-1 | [29] | 0.11[30] | -0.75[31] | -0.81[32] | -1.08[33] | -0.35[34] | -0.66[35] |
6 | PARP1 | Poly [ADP-ribose] polymerase 1 | [36] | 0.73[37] | 1.16[38] | 1.58[39] | 1.15[40] | 0.83[41] | 0.73[42] |
7 | CFLAR | CASP8 and FADD-like apoptosis regulator | [43] | 0.22[44] | 1.64[45] | 0.87[46] | 0.08[47] | 0.40[48] | 2.71[49] |
8 | DAXX | Death domain-associated protein 6 | [50] | 0.77[51] | 1.31[52] | 0.58[53] | 0.78[54] | 0.81[55] | 0.19[56] |
9 | CYCS | Cytochrome c | [57] | 1.94[58] | 2.81[59] | 2.56[60] | 1.96[61] | 2.52[62] | 2.46[63] |
10 | MAPKAPK | MAP kinase-activated protein kinase 2 | [64] | 1.06[65] | 0.78[66] | 0.86[67] | 2.02[68] | 1.39[69] | 0.20[70] |
11 | CASP3 | Caspase-3 | [71] | 0.74[72] | 2.09[73] | -0.78[74] | -0.27[75] | 0.88[76] | 0.34[77] |
12 | SPTAN1 | Spectrin alpha chain, non-erythrocytic 1 | [78] | 3.35[79] | 3.36[80] | 3.71[81] | 3.38[82] | 3.67[83] | 3.09[84] |
13 | DFFA | DNA fragmentation factor subunit alpha | [85] | 0.37[86] | 1.40[87] | 0.75[88] | 0.36[89] | 0.55[90] | 0.88[91] |
14 | PAK2 | Serine/threonine-protein kinase PAK 2 | [92] | 2.05[93] | 2.47[94] | 2.44[95] | 1.38[96] | 2.08[97] | 2.51[98] |
15 | FAS | Tumor necrosis factor receptor superfamily member 6 | [99] | -1.00[100] | 0.46[101] | -7.88[102] | -1.12[103] | -0.44[104] | -0.58[105] |
16 | CASP7 | Caspase-7 | [106] | 0.29[107] | 0.61[108] | 0.72[109] | -0.27[110] | 0.09[111] | 0.66[112] |
17 | FADD | FAS-associated death domain protein | [113] | 0.64[114] | 0.61[115] | 1.01[116] | 2.56[117] | 0.53[118] | -0.63[119] |
18 | CASP8 | Caspase-8 | [120] | 0.62[121] | 1.87[122] | 0.72[123] | 0.54[124] | -0.04[125] | -0.27[126] |
19 | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7 | [127] | 0.50[128] | 2.25[129] | 1.80[130] | 1.11[131] | 1.45[132] | 1.39[133] |
20 | CASP6 | Caspase-6 | [134] | -0.66[135] | 0.22[136] | 0.26[137] | -0.33[138] | -0.49[139] | 0.27[140] |
21 | MAPKAPK | MAP kinase-activated protein kinase 3 | [141] | 1.62[142] | 2.24[143] | 1.00[144] | -0.85[145] | 1.02[146] | 0.91[147] |
22 | FAF1 | FAS-associated factor 1 | [148] | 0.65[149] | 1.19[150] | 1.72[151] | 0.98[152] | 1.21[153] | 1.06[154] |
23 | LMNB1 | Lamin-B1 | [155] | 1.58[156] | 2.30[157] | 2.02[158] | 1.94[159] | 1.74[160] | -1.06[161] |
24 | MAPK8 | Mitogen-activated protein kinase 8 | [162] | -0.84[163] | 1.25[164] | -0.21[165] | -0.28[166] | -0.26[167] | 0.63[168] |
25 | ARHGDIB | Rho GDP-dissociation inhibitor 2 | [169] | -4.44[170] | -3.97[171] | -5.24[172] | -0.98[173] | -0.39[174] | 1.87[175] |
26 | LMNB2 | Lamin-B2 | [176] | 3.88[177] | 3.92[178] | 2.77[179] | 2.67[180] | 3.62[181] | -0.26[182] |
27 | NFX1 | Transcriptional repressor NF-X1 | [183] | 1.02[184] | 2.11[185] | 1.99[186] | 1.01[187] | 1.36[188] | 2.80[189] |
28 | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 | [190] | 1.31[191] | 2.62[192] | 1.49[193] | 1.83[194] | 1.39[195] | 2.21[196] |
29 | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2 | [197] | 0.03[198] | 1.31[199] | 0.99[200] | 0.42[201] | 0.55[202] | 0.01[203] |
30 | PRKDC | DNA-dependent protein kinase catalytic subunit | [204] | 4.82[205] | 4.96[206] | 6.52[207] | 5.52[208] | 5.76[209] | 5.38[210] |
31 | RB1 | Retinoblastoma-associated protein | [211] | 1.82[212] | 3.00[213] | 3.23[214] | 2.90[215] | 3.38[216] | 2.62[217] |
32 | CASP9 | Caspase-9 | [218] | 0.76[219] | 2.40[220] | 1.19[221] | 0.87[222] | 0.34[223] | 0.61[224] |
33 | PAK1 | Serine/threonine-protein kinase PAK 1 | [225] | 0.59[226] | 0.51[227] | 2.59[228] | -1.23[229] | 2.71[230] | 1.41[231] |
34 | CASP10 | Caspase-10 | [232] | 1.82[233] | 3.79[234] | 2.42[235] | 1.05[236] | 1.26[237] | 2.21[238] |
35 | APAF1 | Apoptotic protease-activating factor 1 | [239] | 2.26[240] | 3.37[241] | 3.29[242] | 3.25[243] | 2.51[244] | 2.63[245] |
36 | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1 | [246] | 3.25[247] | 3.65[248] | 3.05[249] | 2.95[250] | 1.99[251] | 3.94[252] |
37 | DFFB | DNA fragmentation factor subunit beta | [253] | 1.49[254] | 3.09[255] | 2.12[256] | 1.39[257] | 1.22[258] | 1.78[259] |
38 | ACTA1 | Actin, alpha skeletal muscle | [260] | 1.31[261] | 0.88[262] | -2.48[263] | -4.37[264] | -4.62[265] | -2.27[266] |
39 | TNF | Tumor necrosis factor | [267] | 1.70[268] | 0.25[269] | -4.68[270] | -1.60[271] | -4.66[272] | -0.75[273] |
40 | BCL2 | Apoptosis regulator Bcl-2 | [274] | -2.25[275] | 3.83[276] | -3.90[277] | 2.40[278] | 2.27[279] | 4.38[280] |
41 | FASLG | Tumor necrosis factor ligand superfamily member 6 | [281] | -3.21[282] | -0.66[283] | -4.96[284] | [285] | [286] | 1.73[287] |
42 | IL1A | Interleukin-1 alpha | [288] | 0.18[289] | 0.46[290] | -1.05[291] | -0.02[292] | 6.89[293] | -0.44[294] |
43 | MIR34C | [295] | [296] | [297] | [298] | [299] | [300] | [301] | |
44 | MIR7108 | [302] | [303] | [304] | [305] | [306] | [307] | [308] |