WP_FAMILIAL_HYPERLIPIDEMIA_TYPE_5 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APOA2 Apolipoprotein A-II [1] -0.44[2] -0.26[3] -0.14[4] -6.60[5] -6.50[6] -0.79[7]
2 APOA1 Apolipoprotein A-I [8] -0.42[9] -0.01[10] -1.50[11] -7.11[12] -7.41[13] 0.19[14]
3 APOA5 Apolipoprotein A-V [15] 1.17[16] 2.01[17] 1.01[18] -5.31[19] -4.16[20] 3.51[21]
4 LCAT Phosphatidylcholine-sterol acyltransferase [22] -0.20[23] 1.06[24] -1.29[25] 0.39[26] 1.86[27] 0.85[28]
5 LIPC Hepatic triacylglycerol lipase [29] 1.63[30] 0.89[31] 4.02[32] -2.44[33] -3.13[34] 1.02[35]
6 APOA4 Apolipoprotein A-IV [36] 1.17[37] 2.05[38] -2.80[39] -5.73[40] -7.31[41] 2.63[42]
7 SEL1L Protein sel-1 homolog 1 [43] 4.14[44] 3.71[45] 4.77[46] 7.91[47] 7.47[48] 4.16[49]
8 LDLR Low-density lipoprotein receptor [50] 4.01[51] 3.98[52] 6.13[53] 6.05[54] 7.11[55] 2.57[56]
9 LRP1 Prolow-density lipoprotein receptor-related protein 1 [57] 7.65[58] 5.07[59] 7.20[60] 9.30[61] 9.14[62] 6.49[63]
10 PLTP Phospholipid transfer protein [64] 5.32[65] 4.30[66] 6.83[67] 3.54[68] 8.18[69] 2.96[70]
11 LMF1 Lipase maturation factor 1 [71] 2.95[72] 2.20[73] 4.50[74] 2.75[75] 3.67[76] 2.28[77]
12 CETP Cholesteryl ester transfer protein [78] 2.90[79] 2.65[80] -4.64[81] 7.05[82] 0.99[83] 1.14[84]
13 LPL Lipoprotein lipase [85] [86] [87] -3.32[88] 7.52[89] 3.74[90] 1.10[91]
14 GPIHBP1 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 [92] 0.66[93] [94] 3.69[95] 3.59[96] 6.50[97]
15 MIR6886 [98] [99] [100] [101] [102] [103] [104]
[1]
ref_hepatocyte APOA2
Mean 7.33e+03
Standard deviation 9.4e+03
Values 1.6e+03 2e+04 1.5e+04 2.3e+02 92
[2]
HepG2 APOA2
Mean 848
Standard deviation 2.9e+02
Values 1.1e+03 6.5e+02
[3]
HepG2.C3A APOA2
Mean 1.56e+03
Standard deviation 1.1e+02
Values 1.5e+03 1.6e+03
[4]
HuH.7 APOA2
Mean 738
Standard deviation 1.6e+02
Values 9.2e+02 6.4e+02 6.5e+02
[5]
SNU475 APOA2
Mean 1.12
Standard deviation 0.32
Values 1.4 0.9
[6]
THLE APOA2
Mean 1.48
Standard deviation 0.8
Values 2 0.91
[7]
liver APOA2
Mean 2.39e+03
Standard deviation 2.6e+03
Values 1.8e+02 2.2e+02 5.4e+03 3.7e+03
[8]
ref_hepatocyte APOA1
Mean 5.54e+03
Standard deviation 5.9e+03
Values 9e+02 1.5e+04 7.3e+03 4.7e+03 1.6e+02
[9]
HepG2 APOA1
Mean 647
Standard deviation 1.1e+02
Values 7.2e+02 5.7e+02
[10]
HepG2.C3A APOA1
Mean 1.4e+03
Standard deviation 4.2e+02
Values 1.1e+03 1.7e+03
[11]
HuH.7 APOA1
Mean 217
Standard deviation 31
Values 2.3e+02 2.4e+02 1.8e+02
[12]
SNU475 APOA1
Mean 0.596
Standard deviation 0.16
Values 0.71 0.48
[13]
THLE APOA1
Mean 0.598
Standard deviation 0.26
Values 0.78 0.41
[14]
liver APOA1
Mean 3.55e+03
Standard deviation 3.2e+03
Values 7.4e+02 8.6e+02 6.9e+03 5.7e+03
[15]
ref_hepatocyte APOA5
Mean 59
Standard deviation 65
Values 14 1e+02 1.5e+02 27 0.62
[16]
HepG2 APOA5
Mean 20.8
Standard deviation 0.15
Values 21 21
[17]
HepG2.C3A APOA5
Mean 60.4
Standard deviation 19
Values 47 74
[18]
HuH.7 APOA5
Mean 13.1
Standard deviation 8.4
Values 9.7 23 7
[19]
SNU475 APOA5
Mean 0.0222
Standard deviation 0.012
Values 0.03 0.014
[20]
THLE APOA5
Mean 0.0603
Standard deviation 0.04
Values 0.089 0.032
[21]
liver APOA5
Mean 379
Standard deviation 1.6e+02
Values 3.5e+02 2.1e+02 3.7e+02 5.9e+02
[22]
ref_hepatocyte LCAT
Mean 41.5
Standard deviation 53
Values 9.2 1.2e+02 72 6 0.26
[23]
HepG2 LCAT
Mean 5.64
Standard deviation 1.4
Values 6.6 4.7
[24]
HepG2.C3A LCAT
Mean 22.1
Standard deviation 4.3
Values 19 25
[25]
HuH.7 LCAT
Mean 1.88
Standard deviation 0.21
Values 1.8 2.1 1.7
[26]
SNU475 LCAT
Mean 0.81
Standard deviation 0.048
Values 0.78 0.84
[27]
THLE LCAT
Mean 2.75
Standard deviation 1.3
Values 3.7 1.8
[28]
liver LCAT
Mean 42
Standard deviation 38
Values 18 8.9 94 46
[29]
ref_hepatocyte LIPC
Mean 37.4
Standard deviation 43
Values 4 1.1e+02 52 16 9.2
[30]
HepG2 LIPC
Mean 18.2
Standard deviation 4
Values 21 15
[31]
HepG2.C3A LIPC
Mean 17.6
Standard deviation 9.2
Values 11 24
[32]
HuH.7 LIPC
Mean 67.2
Standard deviation 17
Values 61 86 55
[33]
SNU475 LIPC
Mean 0.103
Standard deviation 0.027
Values 0.12 0.083
[34]
THLE LIPC
Mean 0.0784
Standard deviation 0.002
Values 0.077 0.08
[35]
liver LIPC
Mean 42.7
Standard deviation 5.7
Values 36 44 40 50
[36]
ref_hepatocyte APOA4
Mean 25.6
Standard deviation 28
Values 28 8.8 74 11 5.3
[37]
HepG2 APOA4
Mean 9
Standard deviation 5.6
Values 5 13
[38]
HepG2.C3A APOA4
Mean 27
Standard deviation 5.6
Values 23 31
[39]
HuH.7 APOA4
Mean 0.405
Standard deviation 0.074
Values 0.41 0.47 0.33
[40]
SNU475 APOA4
Mean 0.00717
Standard deviation 0.003
Values 0.0051 0.0093
[41]
THLE APOA4
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[42]
liver APOA4
Mean 89
Standard deviation 1.1e+02
Values 44 21 2.5e+02 39
[43]
ref_hepatocyte SEL1L
Mean 15.3
Standard deviation 6
Values 14 17 23 6.6 15
[44]
HepG2 SEL1L
Mean 42.2
Standard deviation 13
Values 51 33
[45]
HepG2.C3A SEL1L
Mean 50.8
Standard deviation 5.2
Values 54 47
[46]
HuH.7 SEL1L
Mean 46.1
Standard deviation 17
Values 30 64 45
[47]
SNU475 SEL1L
Mean 54.8
Standard deviation 20
Values 40 69
[48]
THLE SEL1L
Mean 49.6
Standard deviation 0.3
Values 49 50
[49]
liver SEL1L
Mean 154
Standard deviation 39
Values 1.7e+02 2e+02 1.1e+02 1.4e+02
[50]
ref_hepatocyte LDLR
Mean 13.7
Standard deviation 8.6
Values 27 4.3 16 7.7 14
[51]
HepG2 LDLR
Mean 34.6
Standard deviation 16
Values 23 46
[52]
HepG2.C3A LDLR
Mean 55.1
Standard deviation 38
Values 29 82
[53]
HuH.7 LDLR
Mean 106
Standard deviation 31
Values 78 1.4e+02 1e+02
[54]
SNU475 LDLR
Mean 13.5
Standard deviation 6.6
Values 8.9 18
[55]
THLE LDLR
Mean 34.7
Standard deviation 13
Values 25 44
[56]
liver LDLR
Mean 45.8
Standard deviation 27
Values 84 24 45 30
[57]
ref_hepatocyte LRP1
Mean 12.6
Standard deviation 14
Values 1.8 29 26 4.1 2.3
[58]
HepG2 LRP1
Mean 396
Standard deviation 1.6e+02
Values 2.8e+02 5.1e+02
[59]
HepG2.C3A LRP1
Mean 108
Standard deviation 18
Values 95 1.2e+02
[60]
HuH.7 LRP1
Mean 204
Standard deviation 59
Values 1.4e+02 2.4e+02 2.4e+02
[61]
SNU475 LRP1
Mean 118
Standard deviation 49
Values 83 1.5e+02
[62]
THLE LRP1
Mean 130
Standard deviation 35
Values 1.1e+02 1.6e+02
[63]
liver LRP1
Mean 635
Standard deviation 3.6e+02
Values 1e+03 8.3e+02 3.4e+02 3.3e+02
[64]
ref_hepatocyte PLTP
Mean 3.71
Standard deviation 2
Values 4.1 5.1 5.3 3.6 0.39
[65]
HepG2 PLTP
Mean 23.2
Standard deviation 9.5
Values 17 30
[66]
HepG2.C3A PLTP
Mean 18.5
Standard deviation 5
Values 15 22
[67]
HuH.7 PLTP
Mean 46.5
Standard deviation 9.6
Values 46 37 57
[68]
SNU475 PLTP
Mean 0.639
Standard deviation 0.45
Values 0.96 0.32
[69]
THLE PLTP
Mean 19.7
Standard deviation 1.5
Values 21 19
[70]
liver PLTP
Mean 16.2
Standard deviation 5.3
Values 21 8.7 17 19
[71]
ref_hepatocyte LMF1
Mean 2.34
Standard deviation 1.9
Values 0.7 4.6 4.3 0.63 1.5
[72]
HepG2 LMF1
Mean 2.83
Standard deviation 1
Values 2.1 3.5
[73]
HepG2.C3A LMF1
Mean 2.72
Standard deviation 2.3
Values 1.1 4.4
[74]
HuH.7 LMF1
Mean 5.84
Standard deviation 1.1
Values 5 5.4 7.1
[75]
SNU475 LMF1
Mean 0.234
Standard deviation 0.19
Values 0.1 0.37
[76]
THLE LMF1
Mean 0.547
Standard deviation 0.089
Values 0.61 0.48
[77]
liver LMF1
Mean 6.38
Standard deviation 2.5
Values 5.4 3.6 9.7 6.8
[78]
ref_hepatocyte CETP
Mean 1.89
Standard deviation 2.7
Values 0 6.1 3.2 0.14 0
[79]
HepG2 CETP
Mean 2.21
Standard deviation 1.2
Values 1.4 3.1
[80]
HepG2.C3A CETP
Mean 3.02
Standard deviation 1.9
Values 1.7 4.4
[81]
HuH.7 CETP
Mean 0.00839
Standard deviation 0.0095
Values 0.019 0.0064 0
[82]
SNU475 CETP
Mean 3.72
Standard deviation 1.8
Values 5 2.4
[83]
THLE CETP
Mean 0.0692
Standard deviation 0.023
Values 0.053 0.085
[84]
liver CETP
Mean 2.35
Standard deviation 1.5
Values 0.85 1.4 2.9 4.2
[85]
ref_hepatocyte LPL
Mean 0.193
Standard deviation 0.37
Values 0.86 0 0.043 0 0.065
[86]
HepG2 LPL
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A LPL
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 LPL
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[89]
SNU475 LPL
Mean 0.525
Standard deviation 0.3
Values 0.74 0.31
[90]
THLE LPL
Mean 0.0473
Standard deviation 0.0083
Values 0.041 0.053
[91]
liver LPL
Mean 0.233
Standard deviation 0.16
Values 0.44 0.057 0.28 0.15
[92]
ref_hepatocyte GPIHBP1
Mean 0.0121
Standard deviation 0.027
Values 0 0 0.06 0 0
[93]
HepG2 GPIHBP1
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A GPIHBP1
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[95]
HuH.7 GPIHBP1
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 GPIHBP1
Mean 0.00232
Standard deviation 0.0033
Values 0 0.0046
[97]
THLE GPIHBP1
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[98]
liver GPIHBP1
Mean 0.614
Standard deviation 0.21
Values 0.5 0.6 0.92 0.44
[99]
ref_hepatocyte MIR6886
Missing
[100]
HepG2 MIR6886
Missing
[101]
HepG2.C3A MIR6886
Missing
[102]
HuH.7 MIR6886
Missing
[103]
SNU475 MIR6886
Missing
[104]
THLE MIR6886
Missing
[105]
liver MIR6886
Missing