WP_FAMILIAL_HYPERLIPIDEMIA_TYPE_3 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APOA2 Apolipoprotein A-II [1] -0.55[2] -0.21[3] -0.35[4] -6.37[5] -6.10[6] -0.63[7]
2 APOA1 Apolipoprotein A-I [8] -0.53[9] 0.04[10] -1.71[11] -6.88[12] -7.01[13] 0.34[14]
3 APOE Apolipoprotein E [15] 0.05[16] -0.29[17] 0.58[18] -3.60[19] -2.80[20] -0.34[21]
4 SCARB1 Scavenger receptor class B member 1 [22] 4.67[23] 3.58[24] 4.15[25] 6.25[26] 5.11[27] 2.09[28]
5 LCAT Phosphatidylcholine-sterol acyltransferase [29] -0.31[30] 1.11[31] -1.50[32] 0.62[33] 2.26[34] 1.00[35]
6 LIPC Hepatic triacylglycerol lipase [36] 1.52[37] 0.93[38] 3.81[39] -2.21[40] -2.73[41] 1.18[42]
7 APOA4 Apolipoprotein A-IV [43] 1.06[44] 2.10[45] -3.02[46] -5.50[47] -6.91[48] 2.79[49]
8 LDLR Low-density lipoprotein receptor [50] 3.90[51] 4.02[52] 5.91[53] 6.28[54] 7.51[55] 2.72[56]
9 LRP1 Prolow-density lipoprotein receptor-related protein 1 [57] 7.54[58] 5.12[59] 6.98[60] 9.53[61] 9.54[62] 6.64[63]
10 PLTP Phospholipid transfer protein [64] 5.21[65] 4.34[66] 6.61[67] 3.76[68] 8.58[69] 3.12[70]
11 CETP Cholesteryl ester transfer protein [71] 2.79[72] 2.69[73] -4.86[74] 7.28[75] 1.40[76] 1.29[77]
12 VLDLR Very low-density lipoprotein receptor [78] 5.31[79] 3.94[80] 5.23[81] 9.58[82] 7.62[83] 1.13[84]
13 LPL Lipoprotein lipase [85] [86] [87] -3.53[88] 7.75[89] 4.14[90] 1.26[91]
14 MIR6886 [92] [93] [94] [95] [96] [97] [98]
[1]
ref_hepatocyte APOA2
Mean 7.33e+03
Standard deviation 9.4e+03
Values 1.6e+03 2e+04 1.5e+04 2.3e+02 92
[2]
HepG2 APOA2
Mean 848
Standard deviation 2.9e+02
Values 1.1e+03 6.5e+02
[3]
HepG2.C3A APOA2
Mean 1.56e+03
Standard deviation 1.1e+02
Values 1.5e+03 1.6e+03
[4]
HuH.7 APOA2
Mean 738
Standard deviation 1.6e+02
Values 9.2e+02 6.4e+02 6.5e+02
[5]
SNU475 APOA2
Mean 1.12
Standard deviation 0.32
Values 1.4 0.9
[6]
THLE APOA2
Mean 1.48
Standard deviation 0.8
Values 2 0.91
[7]
liver APOA2
Mean 2.39e+03
Standard deviation 2.6e+03
Values 1.8e+02 2.2e+02 5.4e+03 3.7e+03
[8]
ref_hepatocyte APOA1
Mean 5.54e+03
Standard deviation 5.9e+03
Values 9e+02 1.5e+04 7.3e+03 4.7e+03 1.6e+02
[9]
HepG2 APOA1
Mean 647
Standard deviation 1.1e+02
Values 7.2e+02 5.7e+02
[10]
HepG2.C3A APOA1
Mean 1.4e+03
Standard deviation 4.2e+02
Values 1.1e+03 1.7e+03
[11]
HuH.7 APOA1
Mean 217
Standard deviation 31
Values 2.3e+02 2.4e+02 1.8e+02
[12]
SNU475 APOA1
Mean 0.596
Standard deviation 0.16
Values 0.71 0.48
[13]
THLE APOA1
Mean 0.598
Standard deviation 0.26
Values 0.78 0.41
[14]
liver APOA1
Mean 3.55e+03
Standard deviation 3.2e+03
Values 7.4e+02 8.6e+02 6.9e+03 5.7e+03
[15]
ref_hepatocyte APOE
Mean 2.9e+03
Standard deviation 3.4e+03
Values 6.9e+02 8.4e+03 3.7e+03 1.5e+03 1.5e+02
[16]
HepG2 APOE
Mean 509
Standard deviation 94
Values 4.4e+02 5.8e+02
[17]
HepG2.C3A APOE
Mean 586
Standard deviation 2.5e+02
Values 4.1e+02 7.7e+02
[18]
HuH.7 APOE
Mean 555
Standard deviation 1.2e+02
Values 5.9e+02 6.6e+02 4.2e+02
[19]
SNU475 APOE
Mean 3.04
Standard deviation 1.2
Values 3.9 2.2
[20]
THLE APOE
Mean 5.77
Standard deviation 1.1
Values 6.5 5
[21]
liver APOE
Mean 1.15e+03
Standard deviation 6.4e+02
Values 6.9e+02 7.6e+02 2.1e+03 1.1e+03
[22]
ref_hepatocyte SCARB1
Mean 44.8
Standard deviation 36
Values 20 62 1e+02 25 16
[23]
HepG2 SCARB1
Mean 192
Standard deviation 55
Values 1.5e+02 2.3e+02
[24]
HepG2.C3A SCARB1
Mean 132
Standard deviation 31
Values 1.1e+02 1.5e+02
[25]
HuH.7 SCARB1
Mean 102
Standard deviation 6.8
Values 1e+02 1.1e+02 96
[26]
SNU475 SCARB1
Mean 43.3
Standard deviation 12
Values 35 52
[27]
THLE SCARB1
Mean 21.5
Standard deviation 3.1
Values 19 24
[28]
liver SCARB1
Mean 96.6
Standard deviation 43
Values 61 61 1.2e+02 1.4e+02
[29]
ref_hepatocyte LCAT
Mean 41.5
Standard deviation 53
Values 9.2 1.2e+02 72 6 0.26
[30]
HepG2 LCAT
Mean 5.64
Standard deviation 1.4
Values 6.6 4.7
[31]
HepG2.C3A LCAT
Mean 22.1
Standard deviation 4.3
Values 19 25
[32]
HuH.7 LCAT
Mean 1.88
Standard deviation 0.21
Values 1.8 2.1 1.7
[33]
SNU475 LCAT
Mean 0.81
Standard deviation 0.048
Values 0.78 0.84
[34]
THLE LCAT
Mean 2.75
Standard deviation 1.3
Values 3.7 1.8
[35]
liver LCAT
Mean 42
Standard deviation 38
Values 18 8.9 94 46
[36]
ref_hepatocyte LIPC
Mean 37.4
Standard deviation 43
Values 4 1.1e+02 52 16 9.2
[37]
HepG2 LIPC
Mean 18.2
Standard deviation 4
Values 21 15
[38]
HepG2.C3A LIPC
Mean 17.6
Standard deviation 9.2
Values 11 24
[39]
HuH.7 LIPC
Mean 67.2
Standard deviation 17
Values 61 86 55
[40]
SNU475 LIPC
Mean 0.103
Standard deviation 0.027
Values 0.12 0.083
[41]
THLE LIPC
Mean 0.0784
Standard deviation 0.002
Values 0.077 0.08
[42]
liver LIPC
Mean 42.7
Standard deviation 5.7
Values 36 44 40 50
[43]
ref_hepatocyte APOA4
Mean 25.6
Standard deviation 28
Values 28 8.8 74 11 5.3
[44]
HepG2 APOA4
Mean 9
Standard deviation 5.6
Values 5 13
[45]
HepG2.C3A APOA4
Mean 27
Standard deviation 5.6
Values 23 31
[46]
HuH.7 APOA4
Mean 0.405
Standard deviation 0.074
Values 0.41 0.47 0.33
[47]
SNU475 APOA4
Mean 0.00717
Standard deviation 0.003
Values 0.0051 0.0093
[48]
THLE APOA4
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[49]
liver APOA4
Mean 89
Standard deviation 1.1e+02
Values 44 21 2.5e+02 39
[50]
ref_hepatocyte LDLR
Mean 13.7
Standard deviation 8.6
Values 27 4.3 16 7.7 14
[51]
HepG2 LDLR
Mean 34.6
Standard deviation 16
Values 23 46
[52]
HepG2.C3A LDLR
Mean 55.1
Standard deviation 38
Values 29 82
[53]
HuH.7 LDLR
Mean 106
Standard deviation 31
Values 78 1.4e+02 1e+02
[54]
SNU475 LDLR
Mean 13.5
Standard deviation 6.6
Values 8.9 18
[55]
THLE LDLR
Mean 34.7
Standard deviation 13
Values 25 44
[56]
liver LDLR
Mean 45.8
Standard deviation 27
Values 84 24 45 30
[57]
ref_hepatocyte LRP1
Mean 12.6
Standard deviation 14
Values 1.8 29 26 4.1 2.3
[58]
HepG2 LRP1
Mean 396
Standard deviation 1.6e+02
Values 2.8e+02 5.1e+02
[59]
HepG2.C3A LRP1
Mean 108
Standard deviation 18
Values 95 1.2e+02
[60]
HuH.7 LRP1
Mean 204
Standard deviation 59
Values 1.4e+02 2.4e+02 2.4e+02
[61]
SNU475 LRP1
Mean 118
Standard deviation 49
Values 83 1.5e+02
[62]
THLE LRP1
Mean 130
Standard deviation 35
Values 1.1e+02 1.6e+02
[63]
liver LRP1
Mean 635
Standard deviation 3.6e+02
Values 1e+03 8.3e+02 3.4e+02 3.3e+02
[64]
ref_hepatocyte PLTP
Mean 3.71
Standard deviation 2
Values 4.1 5.1 5.3 3.6 0.39
[65]
HepG2 PLTP
Mean 23.2
Standard deviation 9.5
Values 17 30
[66]
HepG2.C3A PLTP
Mean 18.5
Standard deviation 5
Values 15 22
[67]
HuH.7 PLTP
Mean 46.5
Standard deviation 9.6
Values 46 37 57
[68]
SNU475 PLTP
Mean 0.639
Standard deviation 0.45
Values 0.96 0.32
[69]
THLE PLTP
Mean 19.7
Standard deviation 1.5
Values 21 19
[70]
liver PLTP
Mean 16.2
Standard deviation 5.3
Values 21 8.7 17 19
[71]
ref_hepatocyte CETP
Mean 1.89
Standard deviation 2.7
Values 0 6.1 3.2 0.14 0
[72]
HepG2 CETP
Mean 2.21
Standard deviation 1.2
Values 1.4 3.1
[73]
HepG2.C3A CETP
Mean 3.02
Standard deviation 1.9
Values 1.7 4.4
[74]
HuH.7 CETP
Mean 0.00839
Standard deviation 0.0095
Values 0.019 0.0064 0
[75]
SNU475 CETP
Mean 3.72
Standard deviation 1.8
Values 5 2.4
[76]
THLE CETP
Mean 0.0692
Standard deviation 0.023
Values 0.053 0.085
[77]
liver CETP
Mean 2.35
Standard deviation 1.5
Values 0.85 1.4 2.9 4.2
[78]
ref_hepatocyte VLDLR
Mean 1.72
Standard deviation 1.4
Values 3 0.46 1 0.67 3.4
[79]
HepG2 VLDLR
Mean 11.5
Standard deviation 2.9
Values 9.4 14
[80]
HepG2.C3A VLDLR
Mean 6.53
Standard deviation 2.8
Values 4.6 8.5
[81]
HuH.7 VLDLR
Mean 8.31
Standard deviation 0.89
Values 7.3 9 8.6
[82]
SNU475 VLDLR
Mean 16.7
Standard deviation 9.1
Values 10 23
[83]
THLE VLDLR
Mean 4.7
Standard deviation 1.2
Values 5.6 3.8
[84]
liver VLDLR
Mean 1.9
Standard deviation 0.9
Values 1.9 3 0.78 1.9
[85]
ref_hepatocyte LPL
Mean 0.193
Standard deviation 0.37
Values 0.86 0 0.043 0 0.065
[86]
HepG2 LPL
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A LPL
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 LPL
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[89]
SNU475 LPL
Mean 0.525
Standard deviation 0.3
Values 0.74 0.31
[90]
THLE LPL
Mean 0.0473
Standard deviation 0.0083
Values 0.041 0.053
[91]
liver LPL
Mean 0.233
Standard deviation 0.16
Values 0.44 0.057 0.28 0.15
[92]
ref_hepatocyte MIR6886
Missing
[93]
HepG2 MIR6886
Missing
[94]
HepG2.C3A MIR6886
Missing
[95]
HuH.7 MIR6886
Missing
[96]
SNU475 MIR6886
Missing
[97]
THLE MIR6886
Missing
[98]
liver MIR6886
Missing