WP_FAMILIAL_HYPERLIPIDEMIA_TYPE_2 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APOA2 Apolipoprotein A-II [1] -0.98[2] -0.93[3] -0.99[4] -4.71[5] -5.21[6] -1.62[7]
2 APOA1 Apolipoprotein A-I [8] -0.97[9] -0.68[10] -2.35[11] -5.22[12] -6.11[13] -0.64[14]
3 APOB Apolipoprotein B-100 [15] 5.22[16] 4.99[17] 5.14[18] 1.40[19] 0.73[20] 5.37[21]
4 LCAT Phosphatidylcholine-sterol acyltransferase [22] -0.75[23] 0.39[24] -2.14[25] 2.28[26] 3.15[27] 0.02[28]
5 LIPC Hepatic triacylglycerol lipase [29] 1.09[30] 0.21[31] 3.17[32] -0.55[33] -1.83[34] 0.19[35]
6 EPHX2 Bifunctional epoxide hydrolase 2 [36] -0.01[37] 0.80[38] 3.21[39] 2.98[40] 2.48[41] 1.45[42]
7 APOA4 Apolipoprotein A-IV [43] 0.62[44] 1.38[45] -3.65[46] -3.84[47] -6.01[48] 1.80[49]
8 LDLR Low-density lipoprotein receptor [50] 3.46[51] 3.31[52] 5.28[53] 7.94[54] 8.41[55] 1.74[56]
9 GHR Growth hormone receptor [57] -4.48[58] -6.58[59] 0.28[60] 0.75[61] 5.92[62] 2.15[63]
10 USF1 Upstream stimulatory factor 1 [64] 2.17[65] 1.48[66] 3.37[67] 8.57[68] 7.65[69] -0.23[70]
11 PCSK9 Proprotein convertase subtilisin/kexin type 9 [71] 0.32[72] 4.41[73] 6.73[74] 2.85[75] 1.70[76] 1.77[77]
12 LDLRAP1 Low density lipoprotein receptor adapter protein 1 [78] 3.08[79] 2.52[80] 2.55[81] 9.36[82] 8.65[83] 1.29[84]
13 PLTP Phospholipid transfer protein [85] 4.78[86] 3.62[87] 5.98[88] 5.43[89] 9.47[90] 2.13[91]
14 CETP Cholesteryl ester transfer protein [92] 2.35[93] 1.98[94] -5.49[95] 8.94[96] 2.29[97] 0.31[98]
15 LPL Lipoprotein lipase [99] [100] [101] -4.17[102] 9.41[103] 5.04[104] 0.27[105]
16 GPIHBP1 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 [106] -0.01[107] [108] 5.58[109] 4.89[110] 5.67[111]
17 MIR6886 [112] [113] [114] [115] [116] [117] [118]
[1]
ref_hepatocyte APOA2
Mean 7.33e+03
Standard deviation 9.4e+03
Values 1.6e+03 2e+04 1.5e+04 2.3e+02 92
[2]
HepG2 APOA2
Mean 848
Standard deviation 2.9e+02
Values 1.1e+03 6.5e+02
[3]
HepG2.C3A APOA2
Mean 1.56e+03
Standard deviation 1.1e+02
Values 1.5e+03 1.6e+03
[4]
HuH.7 APOA2
Mean 738
Standard deviation 1.6e+02
Values 9.2e+02 6.4e+02 6.5e+02
[5]
SNU475 APOA2
Mean 1.12
Standard deviation 0.32
Values 1.4 0.9
[6]
THLE APOA2
Mean 1.48
Standard deviation 0.8
Values 2 0.91
[7]
liver APOA2
Mean 2.39e+03
Standard deviation 2.6e+03
Values 1.8e+02 2.2e+02 5.4e+03 3.7e+03
[8]
ref_hepatocyte APOA1
Mean 5.54e+03
Standard deviation 5.9e+03
Values 9e+02 1.5e+04 7.3e+03 4.7e+03 1.6e+02
[9]
HepG2 APOA1
Mean 647
Standard deviation 1.1e+02
Values 7.2e+02 5.7e+02
[10]
HepG2.C3A APOA1
Mean 1.4e+03
Standard deviation 4.2e+02
Values 1.1e+03 1.7e+03
[11]
HuH.7 APOA1
Mean 217
Standard deviation 31
Values 2.3e+02 2.4e+02 1.8e+02
[12]
SNU475 APOA1
Mean 0.596
Standard deviation 0.16
Values 0.71 0.48
[13]
THLE APOA1
Mean 0.598
Standard deviation 0.26
Values 0.78 0.41
[14]
liver APOA1
Mean 3.55e+03
Standard deviation 3.2e+03
Values 7.4e+02 8.6e+02 6.9e+03 5.7e+03
[15]
ref_hepatocyte APOB
Mean 165
Standard deviation 1.5e+02
Values 8.3 3.4e+02 2.2e+02 2.4e+02 15
[16]
HepG2 APOB
Mean 1.41e+03
Standard deviation 6.5e+02
Values 1.9e+03 9.5e+02
[17]
HepG2.C3A APOB
Mean 2.13e+03
Standard deviation 5.8e+02
Values 2.5e+03 1.7e+03
[18]
HuH.7 APOB
Mean 1.16e+03
Standard deviation 4.8e+02
Values 6.1e+02 1.5e+03 1.4e+03
[19]
SNU475 APOB
Mean 1.75
Standard deviation 0.12
Values 1.8 1.7
[20]
THLE APOB
Mean 2.04
Standard deviation 0.96
Values 2.7 1.4
[21]
liver APOB
Mean 6.85e+03
Standard deviation 4.5e+03
Values 8.5e+03 1.2e+04 2.9e+03 3.6e+03
[22]
ref_hepatocyte LCAT
Mean 41.5
Standard deviation 53
Values 9.2 1.2e+02 72 6 0.26
[23]
HepG2 LCAT
Mean 5.64
Standard deviation 1.4
Values 6.6 4.7
[24]
HepG2.C3A LCAT
Mean 22.1
Standard deviation 4.3
Values 19 25
[25]
HuH.7 LCAT
Mean 1.88
Standard deviation 0.21
Values 1.8 2.1 1.7
[26]
SNU475 LCAT
Mean 0.81
Standard deviation 0.048
Values 0.78 0.84
[27]
THLE LCAT
Mean 2.75
Standard deviation 1.3
Values 3.7 1.8
[28]
liver LCAT
Mean 42
Standard deviation 38
Values 18 8.9 94 46
[29]
ref_hepatocyte LIPC
Mean 37.4
Standard deviation 43
Values 4 1.1e+02 52 16 9.2
[30]
HepG2 LIPC
Mean 18.2
Standard deviation 4
Values 21 15
[31]
HepG2.C3A LIPC
Mean 17.6
Standard deviation 9.2
Values 11 24
[32]
HuH.7 LIPC
Mean 67.2
Standard deviation 17
Values 61 86 55
[33]
SNU475 LIPC
Mean 0.103
Standard deviation 0.027
Values 0.12 0.083
[34]
THLE LIPC
Mean 0.0784
Standard deviation 0.002
Values 0.077 0.08
[35]
liver LIPC
Mean 42.7
Standard deviation 5.7
Values 36 44 40 50
[36]
ref_hepatocyte EPHX2
Mean 31.5
Standard deviation 40
Values 2.2 93 51 6.6 5.1
[37]
HepG2 EPHX2
Mean 7.16
Standard deviation 2
Values 8.5 5.8
[38]
HepG2.C3A EPHX2
Mean 22.2
Standard deviation 4
Values 19 25
[39]
HuH.7 EPHX2
Mean 58
Standard deviation 2.7
Values 61 55 58
[40]
SNU475 EPHX2
Mean 0.995
Standard deviation 0.55
Values 0.61 1.4
[41]
THLE EPHX2
Mean 1.31
Standard deviation 0.13
Values 1.4 1.2
[42]
liver EPHX2
Mean 85.8
Standard deviation 57
Values 40 42 1.6e+02 1e+02
[43]
ref_hepatocyte APOA4
Mean 25.6
Standard deviation 28
Values 28 8.8 74 11 5.3
[44]
HepG2 APOA4
Mean 9
Standard deviation 5.6
Values 5 13
[45]
HepG2.C3A APOA4
Mean 27
Standard deviation 5.6
Values 23 31
[46]
HuH.7 APOA4
Mean 0.405
Standard deviation 0.074
Values 0.41 0.47 0.33
[47]
SNU475 APOA4
Mean 0.00717
Standard deviation 0.003
Values 0.0051 0.0093
[48]
THLE APOA4
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[49]
liver APOA4
Mean 89
Standard deviation 1.1e+02
Values 44 21 2.5e+02 39
[50]
ref_hepatocyte LDLR
Mean 13.7
Standard deviation 8.6
Values 27 4.3 16 7.7 14
[51]
HepG2 LDLR
Mean 34.6
Standard deviation 16
Values 23 46
[52]
HepG2.C3A LDLR
Mean 55.1
Standard deviation 38
Values 29 82
[53]
HuH.7 LDLR
Mean 106
Standard deviation 31
Values 78 1.4e+02 1e+02
[54]
SNU475 LDLR
Mean 13.5
Standard deviation 6.6
Values 8.9 18
[55]
THLE LDLR
Mean 34.7
Standard deviation 13
Values 25 44
[56]
liver LDLR
Mean 45.8
Standard deviation 27
Values 84 24 45 30
[57]
ref_hepatocyte GHR
Mean 11.8
Standard deviation 18
Values 1.4 44 11 0.44 2.3
[58]
HepG2 GHR
Mean 0.121
Standard deviation 0.032
Values 0.099 0.14
[59]
HepG2.C3A GHR
Mean 0.0501
Standard deviation 0.025
Values 0.032 0.068
[60]
HuH.7 GHR
Mean 2.85
Standard deviation 1.7
Values 1.8 4.8 1.9
[61]
SNU475 GHR
Mean 0.0798
Standard deviation 0.0053
Values 0.076 0.083
[62]
THLE GHR
Mean 5.34
Standard deviation 2.3
Values 7 3.7
[63]
liver GHR
Mean 52.3
Standard deviation 30
Values 94 41 53 22
[64]
ref_hepatocyte USF1
Mean 10.9
Standard deviation 5.8
Values 19 11 14 3.8 7.6
[65]
HepG2 USF1
Mean 11.2
Standard deviation 2.6
Values 13 9.4
[66]
HepG2.C3A USF1
Mean 12.4
Standard deviation 1.8
Values 14 11
[67]
HuH.7 USF1
Mean 22.4
Standard deviation 5.5
Values 28 18 21
[68]
SNU475 USF1
Mean 16.6
Standard deviation 0.23
Values 17 16
[69]
THLE USF1
Mean 16.4
Standard deviation 0.18
Values 16 17
[70]
liver USF1
Mean 9.31
Standard deviation 1.5
Values 9.8 11 9.8 7.2
[71]
ref_hepatocyte PCSK9
Mean 9.97
Standard deviation 5.7
Values 9.8 15 16 5.6 3.3
[72]
HepG2 PCSK9
Mean 2.85
Standard deviation 1.6
Values 4 1.7
[73]
HepG2.C3A PCSK9
Mean 86.2
Standard deviation 65
Values 40 1.3e+02
[74]
HuH.7 PCSK9
Mean 210
Standard deviation 31
Values 2e+02 2.4e+02 1.8e+02
[75]
SNU475 PCSK9
Mean 0.289
Standard deviation 0.022
Values 0.3 0.27
[76]
THLE PCSK9
Mean 0.242
Standard deviation 0.1
Values 0.31 0.17
[77]
liver PCSK9
Mean 34
Standard deviation 15
Values 52 39 18 27
[78]
ref_hepatocyte LDLRAP1
Mean 4.65
Standard deviation 2.5
Values 3.9 5.7 8.1 1.3 4.3
[79]
HepG2 LDLRAP1
Mean 8.97
Standard deviation 0.22
Values 9.1 8.8
[80]
HepG2.C3A LDLRAP1
Mean 10.9
Standard deviation 0.36
Values 11 11
[81]
HuH.7 LDLRAP1
Mean 5.41
Standard deviation 0.72
Values 5.5 4.6 6.1
[82]
SNU475 LDLRAP1
Mean 12.3
Standard deviation 0.53
Values 13 12
[83]
THLE LDLRAP1
Mean 13.9
Standard deviation 0.87
Values 13 15
[84]
liver LDLRAP1
Mean 11.4
Standard deviation 4.1
Values 10 6.2 15 14
[85]
ref_hepatocyte PLTP
Mean 3.71
Standard deviation 2
Values 4.1 5.1 5.3 3.6 0.39
[86]
HepG2 PLTP
Mean 23.2
Standard deviation 9.5
Values 17 30
[87]
HepG2.C3A PLTP
Mean 18.5
Standard deviation 5
Values 15 22
[88]
HuH.7 PLTP
Mean 46.5
Standard deviation 9.6
Values 46 37 57
[89]
SNU475 PLTP
Mean 0.639
Standard deviation 0.45
Values 0.96 0.32
[90]
THLE PLTP
Mean 19.7
Standard deviation 1.5
Values 21 19
[91]
liver PLTP
Mean 16.2
Standard deviation 5.3
Values 21 8.7 17 19
[92]
ref_hepatocyte CETP
Mean 1.89
Standard deviation 2.7
Values 0 6.1 3.2 0.14 0
[93]
HepG2 CETP
Mean 2.21
Standard deviation 1.2
Values 1.4 3.1
[94]
HepG2.C3A CETP
Mean 3.02
Standard deviation 1.9
Values 1.7 4.4
[95]
HuH.7 CETP
Mean 0.00839
Standard deviation 0.0095
Values 0.019 0.0064 0
[96]
SNU475 CETP
Mean 3.72
Standard deviation 1.8
Values 5 2.4
[97]
THLE CETP
Mean 0.0692
Standard deviation 0.023
Values 0.053 0.085
[98]
liver CETP
Mean 2.35
Standard deviation 1.5
Values 0.85 1.4 2.9 4.2
[99]
ref_hepatocyte LPL
Mean 0.193
Standard deviation 0.37
Values 0.86 0 0.043 0 0.065
[100]
HepG2 LPL
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A LPL
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 LPL
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[103]
SNU475 LPL
Mean 0.525
Standard deviation 0.3
Values 0.74 0.31
[104]
THLE LPL
Mean 0.0473
Standard deviation 0.0083
Values 0.041 0.053
[105]
liver LPL
Mean 0.233
Standard deviation 0.16
Values 0.44 0.057 0.28 0.15
[106]
ref_hepatocyte GPIHBP1
Mean 0.0121
Standard deviation 0.027
Values 0 0 0.06 0 0
[107]
HepG2 GPIHBP1
Mean 0
Standard deviation 0
Values 0 0
[108]
HepG2.C3A GPIHBP1
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[109]
HuH.7 GPIHBP1
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 GPIHBP1
Mean 0.00232
Standard deviation 0.0033
Values 0 0.0046
[111]
THLE GPIHBP1
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[112]
liver GPIHBP1
Mean 0.614
Standard deviation 0.21
Values 0.5 0.6 0.92 0.44
[113]
ref_hepatocyte MIR6886
Missing
[114]
HepG2 MIR6886
Missing
[115]
HepG2.C3A MIR6886
Missing
[116]
HuH.7 MIR6886
Missing
[117]
SNU475 MIR6886
Missing
[118]
THLE MIR6886
Missing
[119]
liver MIR6886
Missing