WP_FACTORS_AND_PATHWAYS_AFFECTING_INSULINLIKE_GROWTH_FACTOR_IGF1AKT_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ITGB1 Integrin beta-1 [1] -0.01[2] -0.12[3] -0.03[4] 0.14[5] 0.62[6] -0.37[7]
2 AKT1 RAC-alpha serine/threonine-protein kinase [8] -0.17[9] -0.53[10] -1.65[11] -1.37[12] -0.95[13] -0.77[14]
3 ILK Integrin-linked protein kinase [15] -1.05[16] -1.24[17] -1.35[18] -1.77[19] -2.26[20] -1.98[21]
4 TNFRSF1A Tumor necrosis factor receptor superfamily member 1A [22] -0.72[23] -1.31[24] -1.05[25] -0.96[26] -0.37[27] -0.45[28]
5 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 [29] -0.26[30] -0.64[31] -0.45[32] -1.24[33] -0.66[34] -0.71[35]
6 IGF1 Insulin-like growth factor I [36] -8.67[37] -9.74[38] -7.99[39] -2.86[40] -10.29[41] 0.39[42]
7 AKT1S1 Proline-rich AKT1 substrate 1 [43] -0.71[44] -1.00[45] -0.68[46] -2.07[47] -1.05[48] -1.72[49]
8 EIF4E Eukaryotic translation initiation factor 4E [50] -0.11[51] 0.59[52] -0.08[53] -1.59[54] -0.17[55] -0.36[56]
9 JKAMP JNK1/MAPK8-associated membrane protein [57] -0.73[58] -0.31[59] -0.86[60] -1.02[61] -0.76[62] -0.78[63]
10 EIF2B2 Translation initiation factor eIF-2B subunit beta [64] -0.34[65] -0.55[66] -1.60[67] -1.65[68] -1.25[69] -1.51[70]
11 MLST8 Target of rapamycin complex subunit LST8 [71] -0.42[72] -0.23[73] 0.11[74] -2.30[75] -1.55[76] -1.09[77]
12 WASL Neural Wiskott-Aldrich syndrome protein [78] -0.73[79] 0.21[80] 0.57[81] -0.22[82] -0.66[83] 0.60[84]
13 MAP1LC3A Microtubule-associated proteins 1A/1B light chain 3A [85] -9.28[86] -10.87[87] -10.27[88] -4.56[89] -2.21[90] -1.47[91]
14 PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN -0.78[92] 0.47[93] 0.64[94] -1.89[95] -0.24[96] 1.95[97]
15 NFKB1 Nuclear factor NF-kappa-B p105 subunit [98] 0.42[99] -0.03[100] -0.28[101] -1.57[102] -0.26[103] -0.08[104]
16 SMAD3 Mothers against decapentaplegic homolog 3 [105] 1.68[106] 0.95[107] 1.14[108] 0.48[109] 1.76[110] -0.31[111]
17 PRKAB1 5'-AMP-activated protein kinase subunit beta-1 [112] 0.46[113] 0.86[114] -0.02[115] -1.39[116] -0.88[117] -0.53[118]
18 GSK3B Glycogen synthase kinase-3 beta [119] 1.02[120] 0.52[121] 1.06[122] 0.49[123] 0.72[124] 0.64[125]
19 MTOR Serine/threonine-protein kinase mTOR [126] 2.29[127] 3.17[128] 2.70[129] 1.36[130] 1.84[131] 2.92[132]
20 RPS6KB1 Ribosomal protein S6 kinase beta-1 [133] [134] [135] [136] [137] [138] [139]
21 IRS1 Insulin receptor substrate 1 [140] 1.84[141] 1.16[142] 2.55[143] 0.39[144] 0.36[145] 1.59[146]
22 DEPTOR DEP domain-containing mTOR-interacting protein [147] -3.57[148] -2.51[149] 1.50[150] -5.57[151] -2.53[152] 0.33[153]
23 SMAD2 Mothers against decapentaplegic homolog 2 [154] 1.77[155] 1.90[156] 1.36[157] 1.06[158] 1.65[159] 2.04[160]
24 PLD1 Phospholipase D1 [161] 2.17[162] 2.75[163] 3.21[164] -0.28[165] 0.72[166] 1.53[167]
25 RPTOR Regulatory-associated protein of mTOR [168] 2.84[169] 1.94[170] 2.00[171] 0.53[172] 1.16[173] 1.81[174]
26 PPARGC1A Peroxisome proliferator-activated receptor gamma coactivator 1-alpha -1.33[175] 1.42[176] -9.39[177] -0.56[178] -3.46[179] 2.91[180]
27 PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 2.12[181] 2.70[182] 2.28[183] 1.29[184] -0.08[185] 1.54[186]
28 RICTOR Rapamycin-insensitive companion of mTOR [187] 0.48[188] 2.43[189] 3.07[190] 1.04[191] 1.64[192] 2.99[193]
29 TNFSF9 Tumor necrosis factor ligand superfamily member 9 [194] -0.34[195] -0.74[196] -0.03[197] -0.95[198] -1.56[199] -6.02[200]
30 IGF1R Insulin-like growth factor 1 receptor [201] 4.50[202] 3.67[203] 2.31[204] 3.15[205] 3.10[206] 1.56[207]
31 ACVR2B Activin receptor type-2B [208] 2.03[209] 3.30[210] 4.08[211] -0.23[212] -0.03[213] 2.64[214]
32 FBXO32 F-box only protein 32 [215] -0.80[216] -1.60[217] -0.40[218] 5.33[219] 5.08[220] 1.42[221]
33 IGFBP5 Insulin-like growth factor-binding protein 5 [222] 1.40[223] -2.40[224] 0.59[225] 9.98[226] 2.67[227] 7.21[228]
34 PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [229] [230] [231] 0.02[232] -4.47[233] 3.57[234]
35 NEB Nebulin [235] 1.99[236] 2.89[237] 4.38[238] 2.92[239] -0.56[240] 6.13[241]
36 MSTN Growth/differentiation factor 8 [242] [243] [244] [245] [246] [247] [248]
37 TRIM63 E3 ubiquitin-protein ligase TRIM63 [249] [250] [251] [252] [253] [254] [255]
[1]
ref_hepatocyte ITGB1
Mean 128
Standard deviation 1e+02
Values 1.4e+02 51 58 91 3e+02
[2]
HepG2 ITGB1
Mean 333
Standard deviation 10
Values 3.3e+02 3.4e+02
[3]
HepG2.C3A ITGB1
Mean 301
Standard deviation 47
Values 3.3e+02 2.7e+02
[4]
HuH.7 ITGB1
Mean 317
Standard deviation 16
Values 3e+02 3.3e+02 3.3e+02
[5]
SNU475 ITGB1
Mean 648
Standard deviation 88
Values 5.9e+02 7.1e+02
[6]
THLE ITGB1
Mean 768
Standard deviation 1.5e+02
Values 6.6e+02 8.8e+02
[7]
liver ITGB1
Mean 204
Standard deviation 85
Values 1.6e+02 3.2e+02 1.2e+02 2.1e+02
[8]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 19 32 31 55 50
[9]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 86 89
[10]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 68 65
[11]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 35 23 33
[12]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 57 76
[13]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[14]
liver AKT1
Mean 45.1
Standard deviation 25
Values 79 48 34 20
[15]
ref_hepatocyte ILK
Mean 34.8
Standard deviation 22
Values 65 18 22 19 51
[16]
HepG2 ILK
Mean 44.1
Standard deviation 5.5
Values 48 40
[17]
HepG2.C3A ILK
Mean 37.7
Standard deviation 0.69
Values 37 38
[18]
HuH.7 ILK
Mean 34.3
Standard deviation 5.9
Values 40 29 34
[19]
SNU475 ILK
Mean 46.7
Standard deviation 5.1
Values 43 50
[20]
THLE ILK
Mean 28.3
Standard deviation 5.4
Values 24 32
[21]
liver ILK
Mean 18
Standard deviation 7.1
Values 13 12 20 27
[22]
ref_hepatocyte TNFRSF1A
Mean 30.7
Standard deviation 20
Values 24 48 55 11 15
[23]
HepG2 TNFRSF1A
Mean 49
Standard deviation 6
Values 45 53
[24]
HepG2.C3A TNFRSF1A
Mean 31.7
Standard deviation 8.2
Values 26 37
[25]
HuH.7 TNFRSF1A
Mean 37.3
Standard deviation 0.38
Values 37 37 38
[26]
SNU475 TNFRSF1A
Mean 72.7
Standard deviation 0.99
Values 72 73
[27]
THLE TNFRSF1A
Mean 92.5
Standard deviation 20
Values 78 1.1e+02
[28]
liver TNFRSF1A
Mean 46.1
Standard deviation 22
Values 33 26 51 74
[29]
ref_hepatocyte MAPKAP1
Mean 18.9
Standard deviation 8.4
Values 18 13 16 14 33
[30]
HepG2 MAPKAP1
Mean 41.3
Standard deviation 6.5
Values 46 37
[31]
HepG2.C3A MAPKAP1
Mean 31
Standard deviation 5.4
Values 35 27
[32]
HuH.7 MAPKAP1
Mean 34.6
Standard deviation 7.1
Values 40 26 38
[33]
SNU475 MAPKAP1
Mean 36.6
Standard deviation 8.3
Values 31 43
[34]
THLE MAPKAP1
Mean 46.7
Standard deviation 15
Values 36 57
[35]
liver MAPKAP1
Mean 23.6
Standard deviation 2.7
Values 25 26 23 20
[36]
ref_hepatocyte IGF1
Mean 17.2
Standard deviation 16
Values 5 39 24 0 18
[37]
HepG2 IGF1
Mean 0.111
Standard deviation 0.0052
Values 0.11 0.11
[38]
HepG2.C3A IGF1
Mean 0.0516
Standard deviation 0.018
Values 0.064 0.039
[39]
HuH.7 IGF1
Mean 0.171
Standard deviation 0.058
Values 0.19 0.22 0.11
[40]
SNU475 IGF1
Mean 10.9
Standard deviation 5.6
Values 6.9 15
[41]
THLE IGF1
Mean 0.0535
Standard deviation 0.008
Values 0.059 0.048
[42]
liver IGF1
Mean 46.3
Standard deviation 31
Values 39 24 92 31
[43]
ref_hepatocyte AKT1S1
Mean 16.3
Standard deviation 7.1
Values 22 16 25 9.3 9.6
[44]
HepG2 AKT1S1
Mean 26.1
Standard deviation 2.4
Values 28 24
[45]
HepG2.C3A AKT1S1
Mean 20.9
Standard deviation 0.11
Values 21 21
[46]
HuH.7 AKT1S1
Mean 25.6
Standard deviation 5
Values 27 20 30
[47]
SNU475 AKT1S1
Mean 17.8
Standard deviation 0.54
Values 17 18
[48]
THLE AKT1S1
Mean 30.7
Standard deviation 8
Values 25 36
[49]
liver AKT1S1
Mean 10.2
Standard deviation 7
Values 4.2 4.3 14 18
[50]
ref_hepatocyte EIF4E
Mean 15
Standard deviation 8.3
Values 13 10 7.1 17 28
[51]
HepG2 EIF4E
Mean 36.5
Standard deviation 7.8
Values 42 31
[52]
HepG2.C3A EIF4E
Mean 57.7
Standard deviation 21
Values 72 43
[53]
HuH.7 EIF4E
Mean 35.6
Standard deviation 9.2
Values 41 25 41
[54]
SNU475 EIF4E
Mean 22.8
Standard deviation 0.41
Values 22 23
[55]
THLE EIF4E
Mean 52.1
Standard deviation 2.8
Values 50 54
[56]
liver EIF4E
Mean 24
Standard deviation 12
Values 12 16 33 36
[57]
ref_hepatocyte JKAMP
Mean 12.1
Standard deviation 7.7
Values 8.1 5.2 7.1 17 23
[58]
HepG2 JKAMP
Mean 19.2
Standard deviation 6.4
Values 24 15
[59]
HepG2.C3A JKAMP
Mean 25.1
Standard deviation 8.7
Values 31 19
[60]
HuH.7 JKAMP
Mean 16.8
Standard deviation 1.4
Values 18 16 16
[61]
SNU475 JKAMP
Mean 27.5
Standard deviation 3.6
Values 25 30
[62]
THLE JKAMP
Mean 28
Standard deviation 0.21
Values 28 28
[63]
liver JKAMP
Mean 14.5
Standard deviation 3.8
Values 10 12 18 17
[64]
ref_hepatocyte EIF2B2
Mean 10
Standard deviation 6.4
Values 20 5.8 12 3.9 8.6
[65]
HepG2 EIF2B2
Mean 20.8
Standard deviation 0.41
Values 20 21
[66]
HepG2.C3A EIF2B2
Mean 17.6
Standard deviation 1.4
Values 19 17
[67]
HuH.7 EIF2B2
Mean 8.34
Standard deviation 1.6
Values 9.5 6.6 9
[68]
SNU475 EIF2B2
Mean 14.7
Standard deviation 1.7
Values 16 14
[69]
THLE EIF2B2
Mean 16.4
Standard deviation 0.082
Values 16 16
[70]
liver EIF2B2
Mean 7.22
Standard deviation 2.9
Values 4 6.2 7.8 11
[71]
ref_hepatocyte MLST8
Mean 10
Standard deviation 3.8
Values 14 10 14 7 5.5
[72]
HepG2 MLST8
Mean 19.6
Standard deviation 1.4
Values 19 21
[73]
HepG2.C3A MLST8
Mean 22
Standard deviation 3.6
Values 19 24
[74]
HuH.7 MLST8
Mean 27.2
Standard deviation 3.6
Values 30 23 28
[75]
SNU475 MLST8
Mean 9.36
Standard deviation 0.84
Values 8.8 9.9
[76]
THLE MLST8
Mean 13.3
Standard deviation 1.9
Values 12 15
[77]
liver MLST8
Mean 9.64
Standard deviation 7.6
Values 3.8 2.5 17 15
[78]
ref_hepatocyte WASL
Mean 8.59
Standard deviation 2.4
Values 6.2 8.7 6.4 12 10
[79]
HepG2 WASL
Mean 13.6
Standard deviation 3.9
Values 16 11
[80]
HepG2.C3A WASL
Mean 25.4
Standard deviation 2.9
Values 23 28
[81]
HuH.7 WASL
Mean 32.2
Standard deviation 9.3
Values 25 43 28
[82]
SNU475 WASL
Mean 33.9
Standard deviation 2.2
Values 32 35
[83]
THLE WASL
Mean 21.2
Standard deviation 0.65
Values 21 22
[84]
liver WASL
Mean 26.7
Standard deviation 9.5
Values 19 19 39 30
[85]
ref_hepatocyte MAP1LC3A
Mean 7.47
Standard deviation 7.7
Values 6.6 20 6.7 0.12 3.6
[86]
HepG2 MAP1LC3A
Mean 0.0315
Standard deviation 0.004
Values 0.034 0.029
[87]
HepG2.C3A MAP1LC3A
Mean 0.0102
Standard deviation 0.00071
Values 0.011 0.0097
[88]
HuH.7 MAP1LC3A
Mean 0.0152
Standard deviation 0.017
Values 0 0.013 0.033
[89]
SNU475 MAP1LC3A
Mean 1.45
Standard deviation 0.48
Values 1.1 1.8
[90]
THLE MAP1LC3A
Mean 6.29
Standard deviation 0.45
Values 6.6 6
[91]
liver MAP1LC3A
Mean 5.54
Standard deviation 6.3
Values 0.61 0.49 14 7.4
[92]
ref_hepatocyte PTEN
Mean 6.57
Standard deviation 2.4
Values 5.2 11 7 4.2 5.9
[93]
HepG2 PTEN
Mean 9.98
Standard deviation 2.3
Values 12 8.4
[94]
HepG2.C3A PTEN
Mean 23.3
Standard deviation 3.3
Values 21 26
[95]
HuH.7 PTEN
Mean 25.7
Standard deviation 12
Values 19 39 19
[96]
SNU475 PTEN
Mean 8.16
Standard deviation 1.8
Values 6.9 9.4
[97]
THLE PTEN
Mean 21.8
Standard deviation 0.98
Values 22 21
[98]
liver PTEN
Mean 52
Standard deviation 9.3
Values 53 55 61 39
[99]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[100]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[101]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[102]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[103]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[104]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[105]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[106]
ref_hepatocyte SMAD3
Mean 5.99
Standard deviation 4.6
Values 13 2.2 1.9 4.8 8.4
[107]
HepG2 SMAD3
Mean 50.4
Standard deviation 14
Values 40 60
[108]
HepG2.C3A SMAD3
Mean 29.5
Standard deviation 11
Values 22 37
[109]
HuH.7 SMAD3
Mean 33.2
Standard deviation 6.9
Values 28 41 31
[110]
SNU475 SMAD3
Mean 38.2
Standard deviation 2.7
Values 36 40
[111]
THLE SMAD3
Mean 78.9
Standard deviation 8.4
Values 73 85
[112]
liver SMAD3
Mean 9.85
Standard deviation 3
Values 13 7.4 12 7.1
[113]
ref_hepatocyte PRKAB1
Mean 4.81
Standard deviation 1.6
Values 4.2 6.9 5.3 2.5 5.1
[114]
HepG2 PRKAB1
Mean 17.4
Standard deviation 1
Values 17 18
[115]
HepG2.C3A PRKAB1
Mean 22.4
Standard deviation 1.5
Values 21 23
[116]
HuH.7 PRKAB1
Mean 11.9
Standard deviation 0.19
Values 12 12 12
[117]
SNU475 PRKAB1
Mean 8.43
Standard deviation 1.5
Values 7.4 9.5
[118]
THLE PRKAB1
Mean 10.2
Standard deviation 0.44
Values 9.9 10
[119]
liver PRKAB1
Mean 6.83
Standard deviation 3.2
Values 4 4.5 7.9 11
[120]
ref_hepatocyte GSK3B
Mean 4.16
Standard deviation 1.7
Values 4.9 2.1 2.7 5.2 5.9
[121]
HepG2 GSK3B
Mean 22.1
Standard deviation 6
Values 26 18
[122]
HepG2.C3A GSK3B
Mean 15.3
Standard deviation 2.3
Values 17 14
[123]
HuH.7 GSK3B
Mean 21.8
Standard deviation 5.6
Values 15 26 24
[124]
SNU475 GSK3B
Mean 26.9
Standard deviation 2.6
Values 25 29
[125]
THLE GSK3B
Mean 26.7
Standard deviation 2.9
Values 25 29
[126]
liver GSK3B
Mean 13.2
Standard deviation 3.2
Values 16 15 14 8.6
[127]
ref_hepatocyte MTOR
Mean 3.34
Standard deviation 0.62
Values 4.3 3.2 3.5 2.6 3.1
[128]
HepG2 MTOR
Mean 42.7
Standard deviation 6.3
Values 47 38
[129]
HepG2.C3A MTOR
Mean 76.8
Standard deviation 17
Values 65 89
[130]
HuH.7 MTOR
Mean 54.5
Standard deviation 17
Values 41 50 73
[131]
SNU475 MTOR
Mean 39.4
Standard deviation 0.66
Values 40 39
[132]
THLE MTOR
Mean 46.6
Standard deviation 4.9
Values 43 50
[133]
liver MTOR
Mean 51.8
Standard deviation 18
Values 62 72 34 39
[134]
ref_hepatocyte RPS6KB1
Mean 3.19
Standard deviation 1.6
Values 1.9 2.1 2 5.1 4.9
[135]
HepG2 RPS6KB1
Missing
[136]
HepG2.C3A RPS6KB1
Missing
[137]
HuH.7 RPS6KB1
Missing
[138]
SNU475 RPS6KB1
Missing
[139]
THLE RPS6KB1
Missing
[140]
liver RPS6KB1
Missing
[141]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 2.7 4.7 2.1 4.3 1.5
[142]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 23 35
[143]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 13 22
[144]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 37 48 49
[145]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 22 15
[146]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[147]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 22 18 23 12
[148]
ref_hepatocyte DEPTOR
Mean 2.92
Standard deviation 3
Values 0.49 7.7 4.3 0.98 1.2
[149]
HepG2 DEPTOR
Mean 0.646
Standard deviation 0.42
Values 0.35 0.94
[150]
HepG2.C3A DEPTOR
Mean 1.31
Standard deviation 0.32
Values 1.1 1.5
[151]
HuH.7 DEPTOR
Mean 20.7
Standard deviation 13
Values 12 35 15
[152]
SNU475 DEPTOR
Mean 0.282
Standard deviation 0.12
Values 0.2 0.37
[153]
THLE DEPTOR
Mean 1.97
Standard deviation 0.12
Values 2.1 1.9
[154]
liver DEPTOR
Mean 7.51
Standard deviation 1.7
Values 6.9 7.2 9.9 6
[155]
ref_hepatocyte SMAD2
Mean 2.54
Standard deviation 1.2
Values 1.9 1.6 1.9 4.5 2.8
[156]
HepG2 SMAD2
Mean 22.7
Standard deviation 2.3
Values 24 21
[157]
HepG2.C3A SMAD2
Mean 24.2
Standard deviation 1.1
Values 23 25
[158]
HuH.7 SMAD2
Mean 16.4
Standard deviation 1.6
Values 15 18 17
[159]
SNU475 SMAD2
Mean 24.3
Standard deviation 3.3
Values 22 27
[160]
THLE SMAD2
Mean 31
Standard deviation 0.65
Values 31 32
[161]
liver SMAD2
Mean 21.4
Standard deviation 6.7
Values 25 29 17 15
[162]
ref_hepatocyte PLD1
Mean 2.16
Standard deviation 1.3
Values 0.51 3.9 2.2 2.7 1.5
[163]
HepG2 PLD1
Mean 25.5
Standard deviation 3.1
Values 28 23
[164]
HepG2.C3A PLD1
Mean 37.3
Standard deviation 8.3
Values 31 43
[165]
HuH.7 PLD1
Mean 50.2
Standard deviation 9.4
Values 40 59 52
[166]
SNU475 PLD1
Mean 8.19
Standard deviation 1.4
Values 7.2 9.2
[167]
THLE PLD1
Mean 13.9
Standard deviation 1.2
Values 13 15
[168]
liver PLD1
Mean 12.8
Standard deviation 4.4
Values 17 15 12 7.2
[169]
ref_hepatocyte RPTOR
Mean 1.96
Standard deviation 0.72
Values 2.6 1.2 1.1 2.5 2.4
[170]
HepG2 RPTOR
Mean 36.8
Standard deviation 1
Values 38 36
[171]
HepG2.C3A RPTOR
Mean 19.3
Standard deviation 0.98
Values 19 20
[172]
HuH.7 RPTOR
Mean 19.8
Standard deviation 7.4
Values 17 14 28
[173]
SNU475 RPTOR
Mean 13
Standard deviation 0.49
Values 13 13
[174]
THLE RPTOR
Mean 17.1
Standard deviation 3.1
Values 15 19
[175]
liver RPTOR
Mean 14.1
Standard deviation 7.6
Values 21 20 7.5 7.6
[176]
ref_hepatocyte PPARGC1A
Mean 1.87
Standard deviation 1.7
Values 0.25 1.6 3.2 4 0.26
[177]
HepG2 PPARGC1A
Mean 1.94
Standard deviation 0.37
Values 2.2 1.7
[178]
HepG2.C3A PPARGC1A
Mean 12.8
Standard deviation 3.6
Values 10 15
[179]
HuH.7 PPARGC1A
Mean 0.00701
Standard deviation 0.0065
Values 0 0.013 0.0082
[180]
SNU475 PPARGC1A
Mean 5.83
Standard deviation 1.4
Values 4.9 6.8
[181]
THLE PPARGC1A
Mean 0.662
Standard deviation 0.1
Values 0.73 0.59
[182]
liver PPARGC1A
Mean 28.7
Standard deviation 18
Values 26 54 20 15
[183]
ref_hepatocyte PDK1
Mean 1.82
Standard deviation 1.1
Values 0.89 2.1 1.1 3.7 1.3
[184]
HepG2 PDK1
Mean 20.7
Standard deviation 5.2
Values 24 17
[185]
HepG2.C3A PDK1
Mean 30.3
Standard deviation 3.9
Values 33 28
[186]
HuH.7 PDK1
Mean 22.3
Standard deviation 0.9
Values 21 22 23
[187]
SNU475 PDK1
Mean 20.4
Standard deviation 4.6
Values 17 24
[188]
THLE PDK1
Mean 6.71
Standard deviation 0.29
Values 6.5 6.9
[189]
liver PDK1
Mean 10.8
Standard deviation 3
Values 7.1 12 10 14
[190]
ref_hepatocyte RICTOR
Mean 1.67
Standard deviation 0.88
Values 2.6 1 0.49 2.2 2.1
[191]
HepG2 RICTOR
Mean 6.11
Standard deviation 1
Values 6.8 5.4
[192]
HepG2.C3A RICTOR
Mean 23
Standard deviation 1
Values 24 22
[193]
HuH.7 RICTOR
Mean 35.2
Standard deviation 17
Values 21 54 31
[194]
SNU475 RICTOR
Mean 15.7
Standard deviation 0.97
Values 15 16
[195]
THLE RICTOR
Mean 20.3
Standard deviation 7.9
Values 26 15
[196]
liver RICTOR
Mean 27.1
Standard deviation 8.5
Values 33 35 24 17
[197]
ref_hepatocyte TNFSF9
Mean 0.836
Standard deviation 1.4
Values 0 0.041 0.17 3.3 0.71
[198]
HepG2 TNFSF9
Mean 1.73
Standard deviation 1.5
Values 0.66 2.8
[199]
HepG2.C3A TNFSF9
Mean 1.28
Standard deviation 0.21
Values 1.1 1.4
[200]
HuH.7 TNFSF9
Mean 2.06
Standard deviation 0.37
Values 2 2.5 1.7
[201]
SNU475 TNFSF9
Mean 1.99
Standard deviation 0.6
Values 2.4 1.6
[202]
THLE TNFSF9
Mean 1.11
Standard deviation 0.19
Values 0.97 1.2
[203]
liver TNFSF9
Mean 0.0263
Standard deviation 0.023
Values 0.04 0.014 0 0.051
[204]
ref_hepatocyte IGF1R
Mean 0.745
Standard deviation 1.4
Values 0.29 0.065 0.043 3.3 0.021
[205]
HepG2 IGF1R
Mean 44
Standard deviation 16
Values 33 55
[206]
HepG2.C3A IGF1R
Mean 24.3
Standard deviation 6.5
Values 20 29
[207]
HuH.7 IGF1R
Mean 9.29
Standard deviation 2.1
Values 8.8 7.5 12
[208]
SNU475 IGF1R
Mean 30.3
Standard deviation 1.7
Values 29 32
[209]
THLE IGF1R
Mean 24.8
Standard deviation 4.5
Values 22 28
[210]
liver IGF1R
Mean 4.51
Standard deviation 2.6
Values 7.6 5.8 2.4 2.2
[211]
ref_hepatocyte ACVR2B
Mean 0.673
Standard deviation 0.59
Values 0.36 0.62 0.37 1.7 0.32
[212]
HepG2 ACVR2B
Mean 7.22
Standard deviation 2
Values 5.8 8.6
[213]
HepG2.C3A ACVR2B
Mean 16.9
Standard deviation 7.7
Values 12 22
[214]
HuH.7 ACVR2B
Mean 28.7
Standard deviation 6.3
Values 21 33 32
[215]
SNU475 ACVR2B
Mean 2.64
Standard deviation 0.036
Values 2.7 2.6
[216]
THLE ACVR2B
Mean 2.58
Standard deviation 0.1
Values 2.5 2.6
[217]
liver ACVR2B
Mean 8.61
Standard deviation 5.5
Values 15 11 4.7 3.4
[218]
ref_hepatocyte FBXO32
Mean 0.348
Standard deviation 0.38
Values 1 0.3 0.24 0 0.2
[219]
HepG2 FBXO32
Mean 0.524
Standard deviation 0.18
Values 0.39 0.65
[220]
HepG2.C3A FBXO32
Mean 0.294
Standard deviation 0.052
Values 0.26 0.33
[221]
HuH.7 FBXO32
Mean 0.661
Standard deviation 0.59
Values 0.27 1.3 0.38
[222]
SNU475 FBXO32
Mean 64
Standard deviation 36
Values 39 89
[223]
THLE FBXO32
Mean 45.8
Standard deviation 3.7
Values 43 48
[224]
liver FBXO32
Mean 1.91
Standard deviation 0.69
Values 1.8 1.1 2.7 2
[225]
ref_hepatocyte IGFBP5
Mean 0.107
Standard deviation 0.14
Values 0 0.28 0.24 0 0.018
[226]
HepG2 IGFBP5
Mean 0.738
Standard deviation 0.82
Values 0.16 1.3
[227]
HepG2.C3A IGFBP5
Mean 0.0521
Standard deviation 0.032
Values 0.075 0.029
[228]
HuH.7 IGFBP5
Mean 0.407
Standard deviation 0.31
Values 0.047 0.58 0.59
[229]
SNU475 IGFBP5
Mean 498
Standard deviation 4e+02
Values 2.1e+02 7.8e+02
[230]
THLE IGFBP5
Mean 2.66
Standard deviation 0.089
Values 2.6 2.7
[231]
liver IGFBP5
Mean 32.5
Standard deviation 22
Values 59 16 41 14
[232]
ref_hepatocyte PIK3CG
Mean 0.0637
Standard deviation 0.13
Values 0 0.29 0.026 0 0
[233]
HepG2 PIK3CG
Mean 0
Standard deviation 0
Values 0 0
[234]
HepG2.C3A PIK3CG
Mean 0
Standard deviation 0
Values 0 0
[235]
HuH.7 PIK3CG
Mean 0
Standard deviation 0
Values 0 0 0
[236]
SNU475 PIK3CG
Mean 0.296
Standard deviation 0.1
Values 0.37 0.22
[237]
THLE PIK3CG
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[238]
liver PIK3CG
Mean 1.55
Standard deviation 0.43
Values 1.6 1.9 0.94 1.7
[239]
ref_hepatocyte NEB
Mean 0.0436
Standard deviation 0.069
Values 0.03 0.024 0.16 0 0
[240]
HepG2 NEB
Mean 0.453
Standard deviation 0.0085
Values 0.46 0.45
[241]
HepG2.C3A NEB
Mean 0.828
Standard deviation 0.35
Values 1.1 0.58
[242]
HuH.7 NEB
Mean 2.29
Standard deviation 1
Values 1.3 3.3 2.2
[243]
SNU475 NEB
Mean 1.51
Standard deviation 0.22
Values 1.4 1.7
[244]
THLE NEB
Mean 0.115
Standard deviation 0.08
Values 0.17 0.059
[245]
liver NEB
Mean 6.26
Standard deviation 4
Values 9.1 5.2 9.7 1.1
[246]
ref_hepatocyte MSTN
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[247]
HepG2 MSTN
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[248]
HepG2.C3A MSTN
Mean 0.0292
Standard deviation 0.041
Values 0 0.058
[249]
HuH.7 MSTN
Mean 0.00625
Standard deviation 0.011
Values 0.019 0 0
[250]
SNU475 MSTN
Mean 0.0125
Standard deviation 0.011
Values 0.02 0.0046
[251]
THLE MSTN
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[252]
liver MSTN
Mean 0.0804
Standard deviation 0.14
Values 0.04 0 0.28 0
[253]
ref_hepatocyte TRIM63
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[254]
HepG2 TRIM63
Mean 0
Standard deviation 0
Values 0 0
[255]
HepG2.C3A TRIM63
Mean 0
Standard deviation 0
Values 0 0
[256]
HuH.7 TRIM63
Mean 0
Standard deviation 0
Values 0 0 0
[257]
SNU475 TRIM63
Mean 0.0203
Standard deviation 0.029
Values 0.041 0
[258]
THLE TRIM63
Mean 0.0139
Standard deviation 0.0029
Values 0.012 0.016
[259]
liver TRIM63
Mean 0.0194
Standard deviation 0.013
Values 0 0.029 0.024 0.026