WP_ESTROGEN_RECEPTOR_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PCK1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] [1] -7.74[2] -3.84[3] -11.09[4] [5] -15.55[6] 0.00[7]
2 CYP1A2 Cytochrome P450 1A2 [8] -9.60[9] -8.67[10] -8.89[11] -7.99[12] -9.31[13] -2.71[14]
3 CYP1A1 Cytochrome P450 1A1 [15] -3.15[16] -5.10[17] -1.01[18] -3.39[19] -4.84[20] -6.86[21]
4 JUN Transcription factor AP-1 [22] 0.82[23] -1.08[24] -0.38[25] 0.39[26] 0.06[27] -2.87[28]
5 STAT3 Signal transducer and activator of transcription 3 [29] 1.86[30] 0.00[31] 1.18[32] 2.33[33] 0.71[34] 1.35[35]
6 NR0B2 Nuclear receptor subfamily 0 group B member 2 [36] 0.89[37] 1.80[38] -4.47[39] -7.48[40] -8.63[41] -1.12[42]
7 GPAM Glycerol-3-phosphate acyltransferase 1, mitochondrial [43] 2.23[44] 3.34[45] 2.52[46] -1.22[47] 2.02[48] 1.61[49]
8 ACOX1 Peroxisomal acyl-coenzyme A oxidase 1 [50] 2.24[51] 2.31[52] 2.24[53] 1.66[54] 0.42[55] 2.02[56]
9 PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial -4.94[57] -7.57[58] -4.17[59] -0.23[60] 3.65[61] 1.55[62]
10 PPARA Peroxisome proliferator-activated receptor alpha [63] 1.99[64] 2.60[65] 3.89[66] 2.13[67] 0.39[68] 3.09[69]
11 SP1 Transcription factor Sp1 [70] 3.13[71] 3.01[72] 4.51[73] 4.76[74] 3.55[75] 1.09[76]
12 CYP1B1 Cytochrome P450 1B1 [77] -5.73[78] -5.53[79] -0.99[80] 3.60[81] 5.30[82] -0.05[83]
13 ESR1 Estrogen receptor [84] -5.99[85] [86] -4.40[87] -2.08[88] -5.24[89] 1.34[90]
[1]
ref_hepatocyte PCK1
Mean 142
Standard deviation 1.9e+02
Values 5.3 2.4e+02 4.4e+02 30 0.041
[2]
HepG2 PCK1
Mean 0.593
Standard deviation 0.35
Values 0.34 0.84
[3]
HepG2.C3A PCK1
Mean 10.1
Standard deviation 5.7
Values 6 14
[4]
HuH.7 PCK1
Mean 0.0471
Standard deviation 0.082
Values 0 0.14 0
[5]
SNU475 PCK1
Mean 0
Standard deviation 0
Values 0 0
[6]
THLE PCK1
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[7]
liver PCK1
Mean 420
Standard deviation 94
Values 3.2e+02 4.8e+02 3.7e+02 5.2e+02
[8]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.97 3e+02 71 0.4 18
[9]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.13 0.052
[10]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.15 0.24
[11]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.15 0.1 0.11
[12]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.2 0.07
[13]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[14]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 19 12 55 58
[15]
ref_hepatocyte CYP1A1
Mean 43.8
Standard deviation 36
Values 0.06 82 17 77 43
[16]
HepG2 CYP1A1
Mean 4.39
Standard deviation 2.6
Values 2.6 6.2
[17]
HepG2.C3A CYP1A1
Mean 1.3
Standard deviation 0.1
Values 1.2 1.4
[18]
HuH.7 CYP1A1
Mean 15.8
Standard deviation 1.4
Values 17 17 14
[19]
SNU475 CYP1A1
Mean 1.8
Standard deviation 1.8
Values 3.1 0.49
[20]
THLE CYP1A1
Mean 1.38
Standard deviation 0.04
Values 1.4 1.4
[21]
liver CYP1A1
Mean 1.12
Standard deviation 0.58
Values 1.8 0.47 1.2 0.92
[22]
ref_hepatocyte JUN
Mean 42.9
Standard deviation 25
Values 66 20 73 26 30
[23]
HepG2 JUN
Mean 67.5
Standard deviation 36
Values 42 93
[24]
HepG2.C3A JUN
Mean 20.6
Standard deviation 11
Values 13 28
[25]
HuH.7 JUN
Mean 23.9
Standard deviation 19
Values 14 46 11
[26]
SNU475 JUN
Mean 24.2
Standard deviation 4.1
Values 27 21
[27]
THLE JUN
Mean 40.2
Standard deviation 4.7
Values 37 44
[28]
liver JUN
Mean 17.4
Standard deviation 8.4
Values 12 24 25 8.4
[29]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 18 36 46 26 25
[30]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 1e+02 90
[31]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 27 34
[32]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 35 65 47
[33]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 57 74
[34]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[35]
liver STAT3
Mean 227
Standard deviation 42
Values 2e+02 2.3e+02 1.9e+02 2.8e+02
[36]
ref_hepatocyte NR0B2
Mean 23.4
Standard deviation 25
Values 16 44 55 0.37 1.2
[37]
HepG2 NR0B2
Mean 38.6
Standard deviation 7.8
Values 44 33
[38]
HepG2.C3A NR0B2
Mean 83
Standard deviation 18
Values 71 95
[39]
HuH.7 NR0B2
Mean 0.766
Standard deviation 0.29
Values 1 0.82 0.45
[40]
SNU475 NR0B2
Mean 0.0568
Standard deviation 0.034
Values 0.081 0.032
[41]
THLE NR0B2
Mean 0.0532
Standard deviation 3.6e-05
Values 0.053 0.053
[42]
liver NR0B2
Mean 32
Standard deviation 38
Values 3.3 5 86 34
[43]
ref_hepatocyte GPAM
Mean 15.2
Standard deviation 15
Values 5.1 42 14 9.5 5.2
[44]
HepG2 GPAM
Mean 63.3
Standard deviation 9.1
Values 57 70
[45]
HepG2.C3A GPAM
Mean 157
Standard deviation 16
Values 1.5e+02 1.7e+02
[46]
HuH.7 GPAM
Mean 63
Standard deviation 14
Values 51 78 59
[47]
SNU475 GPAM
Mean 2.82
Standard deviation 1.7
Values 4 1.6
[48]
THLE GPAM
Mean 55.7
Standard deviation 16
Values 45 67
[49]
liver GPAM
Mean 138
Standard deviation 82
Values 1.3e+02 1.1e+02 2.5e+02 59
[50]
ref_hepatocyte ACOX1
Mean 11.2
Standard deviation 8.5
Values 2.3 23 11 15 4.5
[51]
HepG2 ACOX1
Mean 46.9
Standard deviation 9
Values 53 41
[52]
HepG2.C3A ACOX1
Mean 56.3
Standard deviation 2.2
Values 55 58
[53]
HuH.7 ACOX1
Mean 38.2
Standard deviation 5
Values 38 33 43
[54]
SNU475 ACOX1
Mean 15.2
Standard deviation 4.1
Values 12 18
[55]
THLE ACOX1
Mean 13.4
Standard deviation 1.8
Values 12 15
[56]
liver ACOX1
Mean 134
Standard deviation 77
Values 2.2e+02 1.8e+02 63 75
[57]
ref_hepatocyte PDK4
Mean 6.64
Standard deviation 8
Values 0.83 20 8.4 0.25 3.9
[58]
HepG2 PDK4
Mean 0.192
Standard deviation 0.14
Values 0.29 0.092
[59]
HepG2.C3A PDK4
Mean 0.0355
Standard deviation 0.0047
Values 0.032 0.039
[60]
HuH.7 PDK4
Mean 0.267
Standard deviation 0.054
Values 0.21 0.28 0.31
[61]
SNU475 PDK4
Mean 2.44
Standard deviation 0.53
Values 2.1 2.8
[62]
THLE PDK4
Mean 75.1
Standard deviation 8.3
Values 81 69
[63]
liver PDK4
Mean 57.6
Standard deviation 22
Values 72 35 82 42
[64]
ref_hepatocyte PPARA
Mean 3.95
Standard deviation 2.1
Values 1.6 6.2 5.5 4.6 1.9
[65]
HepG2 PPARA
Mean 13.9
Standard deviation 0.43
Values 14 14
[66]
HepG2.C3A PPARA
Mean 24.4
Standard deviation 5.6
Values 20 28
[67]
HuH.7 PPARA
Mean 42.3
Standard deviation 18
Values 25 60 42
[68]
SNU475 PPARA
Mean 7.44
Standard deviation 1.6
Values 6.3 8.5
[69]
THLE PPARA
Mean 4.68
Standard deviation 0.38
Values 4.9 4.4
[70]
liver PPARA
Mean 99.6
Standard deviation 24
Values 79 1.3e+02 88 97
[71]
ref_hepatocyte SP1
Mean 3.57
Standard deviation 0.42
Values 4.3 3.6 3.5 3.2 3.3
[72]
HepG2 SP1
Mean 27.8
Standard deviation 1
Values 29 27
[73]
HepG2.C3A SP1
Mean 29.3
Standard deviation 0.25
Values 29 29
[74]
HuH.7 SP1
Mean 58.8
Standard deviation 12
Values 46 59 71
[75]
SNU475 SP1
Mean 41.7
Standard deviation 2.6
Values 40 44
[76]
THLE SP1
Mean 37.5
Standard deviation 7.4
Values 32 43
[77]
liver SP1
Mean 22.6
Standard deviation 13
Values 36 31 14 9.1
[78]
ref_hepatocyte CYP1B1
Mean 2.62
Standard deviation 3.2
Values 0.92 1.4 2.7 0.024 8
[79]
HepG2 CYP1B1
Mean 0.0437
Standard deviation 0.019
Values 0.03 0.057
[80]
HepG2.C3A CYP1B1
Mean 0.0575
Standard deviation 0.04
Values 0.086 0.029
[81]
HuH.7 CYP1B1
Mean 0.95
Standard deviation 0.082
Values 0.95 1 0.87
[82]
SNU475 CYP1B1
Mean 13.6
Standard deviation 3.1
Values 11 16
[83]
THLE CYP1B1
Mean 93
Standard deviation 14
Values 1e+02 83
[84]
liver CYP1B1
Mean 7.5
Standard deviation 1.4
Values 6.2 7.4 6.9 9.5
[85]
ref_hepatocyte ESR1
Mean 1.54
Standard deviation 2.3
Values 0 5.3 2.2 0 0.17
[86]
HepG2 ESR1
Mean 0.0215
Standard deviation 0.018
Values 0.0086 0.034
[87]
HepG2.C3A ESR1
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 ESR1
Mean 0.0525
Standard deviation 0.047
Values 0.019 0.032 0.11
[89]
SNU475 ESR1
Mean 0.157
Standard deviation 0.14
Values 0.25 0.06
[90]
THLE ESR1
Mean 0.0367
Standard deviation 0.0067
Values 0.041 0.032
[91]
liver ESR1
Mean 11.5
Standard deviation 7
Values 22 11 7.2 6.1