WP_ENVELOPE_PROTEINS_AND_THEIR_POTENTIAL_ROLES_IN_EDMD_PHYSIOPATHOLOGY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CFL1 | Cofilin-1 | [1] | -0.32[2] | -1.18[3] | -1.35[4] | -0.86[5] | -0.68[6] | -0.97[7] |
2 | RHOA | Transforming protein RhoA | [8] | -1.00[9] | -1.33[10] | -1.26[11] | -1.62[12] | -1.05[13] | -1.35[14] |
3 | BANF1 | Barrier-to-autointegration factor | [15] | -2.07[16] | -1.80[17] | -2.39[18] | -2.29[19] | -2.31[20] | -2.84[21] |
4 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [22] | -0.98[23] | -1.15[24] | -0.72[25] | -0.94[26] | -0.32[27] | -1.22[28] |
5 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [29] | 0.00[30] | -0.16[31] | 0.56[32] | -1.24[33] | -0.64[34] | -1.73[35] |
6 | GRB2 | Growth factor receptor-bound protein 2 | [36] | 1.14[37] | 1.14[38] | 1.11[39] | 0.16[40] | 0.19[41] | 0.27[42] |
7 | EMD | Emerin | [43] | -1.14[44] | -1.03[45] | -1.46[46] | -0.82[47] | -0.71[48] | -2.08[49] |
8 | NRAS | GTPase NRas | [50] | 0.57[51] | 1.17[52] | 1.43[53] | 0.60[54] | 0.29[55] | -0.28[56] |
9 | KIF5B | Kinesin-1 heavy chain | [57] | 0.35[58] | 2.50[59] | 2.10[60] | 2.46[61] | 1.65[62] | 1.30[63] |
10 | SUN1 | SUN domain-containing protein 1 | [64] | 0.34[65] | 0.13[66] | 0.99[67] | -0.34[68] | 0.50[69] | 0.47[70] |
11 | HRAS | GTPase HRas | [71] | -1.06[72] | -1.60[73] | -2.55[74] | -1.34[75] | -1.44[76] | -2.69[77] |
12 | MAPK1 | Mitogen-activated protein kinase 1 | [78] | 1.65[79] | 1.96[80] | 1.63[81] | 1.45[82] | 1.22[83] | 1.75[84] |
13 | LBR | Lamin-B receptor | [85] | 0.68[86] | 1.56[87] | 2.26[88] | 0.94[89] | 0.10[90] | 0.76[91] |
14 | TMPO | Lamina-associated polypeptide 2, isoform alpha | [92] | 0.90[93] | 1.83[94] | 1.95[95] | 1.76[96] | 1.77[97] | 0.77[98] |
15 | KRAS | GTPase KRas | [99] | -0.57[100] | -0.43[101] | 1.02[102] | 0.41[103] | 0.18[104] | 0.65[105] |
16 | TMEM43 | Transmembrane protein 43 | [106] | 1.17[107] | 1.33[108] | 0.82[109] | -0.06[110] | 0.84[111] | 0.09[112] |
17 | YY1AP1 | YY1-associated protein 1 | [113] | -0.20[114] | -0.24[115] | 0.34[116] | 0.38[117] | 0.00[118] | 0.12[119] |
18 | SOS1 | Son of sevenless homolog 1 | [120] | -0.16[121] | 1.54[122] | 0.89[123] | 0.45[124] | -0.20[125] | 0.51[126] |
19 | SRF | Serum response factor | [127] | 1.41[128] | 1.13[129] | 0.25[130] | 1.14[131] | 0.34[132] | -0.81[133] |
20 | SMAD3 | Mothers against decapentaplegic homolog 3 | [134] | 1.88[135] | 1.43[136] | 1.51[137] | 1.40[138] | 2.40[139] | 0.18[140] |
21 | PLEC | Plectin | [141] | 3.34[142] | 1.10[143] | 2.35[144] | 4.28[145] | 4.04[146] | 3.97[147] |
22 | SYNE2 | Nesprin-2 | [148] | -1.72[149] | 0.43[150] | 0.90[151] | 0.17[152] | 0.22[153] | 3.83[154] |
23 | MAPK3 | Mitogen-activated protein kinase 3 | [155] | 1.79[156] | 2.00[157] | 1.89[158] | 0.03[159] | 0.16[160] | -1.07[161] |
24 | SMAD4 | Mothers against decapentaplegic homolog 4 | [162] | 1.34[163] | 2.13[164] | 1.95[165] | 1.51[166] | 2.00[167] | 2.76[168] |
25 | TGFB2 | Transforming growth factor beta-2 | [169] | -4.35[170] | -6.71[171] | -1.06[172] | 3.06[173] | 1.78[174] | -2.80[175] |
26 | ADCY9 | Adenylate cyclase type 9 | [176] | 2.56[177] | 1.92[178] | 2.19[179] | 0.56[180] | 0.22[181] | 2.38[182] |
27 | SOS2 | Son of sevenless homolog 2 | [183] | -0.08[184] | 1.21[185] | 0.29[186] | 1.29[187] | 1.27[188] | 1.81[189] |
28 | SMAD2 | Mothers against decapentaplegic homolog 2 | [190] | 1.96[191] | 2.39[192] | 1.73[193] | 1.99[194] | 2.29[195] | 2.54[196] |
29 | LEMD3 | Inner nuclear membrane protein Man1 | [197] | 0.84[198] | 1.99[199] | 1.78[200] | 0.82[201] | 1.42[202] | 1.43[203] |
30 | TGFB1 | Transforming growth factor beta-1 | [204] | 3.42[205] | 2.54[206] | -0.36[207] | 3.44[208] | 2.79[209] | -1.26[210] |
31 | ADCY6 | Adenylate cyclase type 6 | [211] | 1.99[212] | 2.62[213] | 2.43[214] | 2.11[215] | 2.90[216] | 2.61[217] |
32 | TGFB3 | Transforming growth factor beta-3 | [218] | -1.60[219] | -2.31[220] | -2.70[221] | -0.23[222] | -1.17[223] | 0.43[224] |
33 | ADCY1 | Adenylate cyclase type 1 | [225] | -0.89[226] | -2.60[227] | -2.95[228] | -2.50[229] | -2.41[230] | 4.97[231] |
34 | MAP3K9 | Mitogen-activated protein kinase kinase kinase 9 | [232] | 2.16[233] | 1.85[234] | 1.52[235] | 2.18[236] | 0.52[237] | 1.66[238] |
35 | SYNE1 | Nesprin-1 | [239] | 2.39[240] | 3.22[241] | 2.82[242] | 3.06[243] | 3.11[244] | 6.20[245] |
36 | ADCY7 | Adenylate cyclase type 7 | [246] | 3.46[247] | 3.24[248] | 2.05[249] | 2.91[250] | 2.50[251] | 2.89[252] |
37 | ADCY10 | Adenylate cyclase type 10 | [253] | -2.26[254] | -2.97[255] | 3.02[256] | -1.35[257] | -4.03[258] | 2.74[259] |
38 | ADCY3 | Adenylate cyclase type 3 | [260] | 1.40[261] | 0.32[262] | 3.50[263] | 4.34[264] | 5.99[265] | 3.49[266] |
39 | ADCY2 | Adenylate cyclase type 2 | [267] | -5.44[268] | -3.34[269] | -4.75[270] | -3.13[271] | -4.13[272] | -4.15[273] |
40 | ADCY5 | Adenylate cyclase type 5 | [274] | 0.10[275] | 1.26[276] | 2.14[277] | 0.25[278] | 1.49[279] | 6.35[280] |
41 | ADCY4 | Adenylate cyclase type 4 | [281] | 0.03[282] | -0.87[283] | 1.62[284] | [285] | [286] | 8.34[287] |
42 | CCN2 | [288] | [289] | [290] | [291] | [292] | [293] | [294] | |
43 | SYNE3 | Nesprin-3 | [295] | [296] | [297] | [298] | [299] | [300] | [301] |
44 | TAFAZZIN | [302] | [303] | [304] | [305] | [306] | [307] | [308] | |
45 | SYNE4 | Nesprin-4 | [309] | [310] | [311] | [312] | [313] | [314] | [315] |
46 | ADCY8 | Adenylate cyclase type 8 | [316] | [317] | [318] | [319] | [320] | [321] | [322] |