WP_ENDOPLASMIC_RETICULUM_STRESS_RESPONSE_IN_CORONAVIRUS_INFECTION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | HSPA5 | 78 kDa glucose-regulated protein | [1] | 0.07[2] | -0.16[3] | -1.05[4] | -0.60[5] | -0.38[6] | -0.15[7] |
2 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | [8] | -0.64[9] | 0.15[10] | -0.08[11] | -2.32[12] | -0.75[13] | -2.03[14] |
3 | XBP1 | X-box-binding protein 1 | [15] | -1.02[16] | -1.05[17] | 0.49[18] | -2.19[19] | -2.34[20] | 0.56[21] |
4 | PPP1R14B | Protein phosphatase 1 regulatory subunit 14B | [22] | -0.93[23] | -1.47[24] | -2.13[25] | -0.99[26] | -1.36[27] | -3.47[28] |
5 | PPP1R15A | Protein phosphatase 1 regulatory subunit 15A | [29] | -1.23[30] | -2.48[31] | -2.11[32] | -1.51[33] | -0.43[34] | -3.43[35] |
6 | PPP1CA | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | [36] | 0.50[37] | -0.08[38] | 1.00[39] | 2.24[40] | -0.03[41] | -0.77[42] |
7 | PPP1R1A | Protein phosphatase 1 regulatory subunit 1A | [43] | -9.33[44] | [45] | -9.08[46] | -11.73[47] | -12.26[48] | 0.00[49] |
8 | PPP1CB | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | [50] | 0.28[51] | 0.55[52] | 0.50[53] | 1.47[54] | 1.41[55] | 0.68[56] |
9 | PPP1CC | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | 1.20[57] | 1.69[58] | 1.77[59] | 0.94[60] | 1.17[61] | -0.89[62] | |
10 | DDIT3 | DNA damage-inducible transcript 3 protein | [63] | -1.46[64] | -0.99[65] | -1.30[66] | -1.40[67] | -0.39[68] | -2.00[69] |
11 | PPP1R7 | Protein phosphatase 1 regulatory subunit 7 | [70] | -0.32[71] | -0.85[72] | -1.25[73] | -0.85[74] | -0.29[75] | -1.26[76] |
12 | EIF2AK1 | Eukaryotic translation initiation factor 2-alpha kinase 1 | [77] | 1.88[78] | 1.81[79] | 1.65[80] | 1.11[81] | 1.37[82] | 0.89[83] |
13 | PPP1R3C | Protein phosphatase 1 regulatory subunit 3C | [84] | -0.63[85] | -1.80[86] | -1.57[87] | -1.37[88] | -2.07[89] | 0.92[90] |
14 | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1 | [91] | 0.80[92] | 0.43[93] | 0.03[94] | 1.31[95] | 1.90[96] | 0.59[97] |
15 | PPP1R11 | Protein phosphatase 1 regulatory subunit 11 | [98] | 0.45[99] | -0.44[100] | -0.94[101] | 1.05[102] | 0.21[103] | -0.49[104] |
16 | MBTPS1 | Membrane-bound transcription factor site-1 protease | [105] | 2.11[106] | 1.62[107] | 1.47[108] | 2.09[109] | 2.28[110] | 1.50[111] |
17 | PPP1R16A | Protein phosphatase 1 regulatory subunit 16A | [112] | -0.01[113] | 0.76[114] | 0.09[115] | -0.12[116] | -0.92[117] | 0.69[118] |
18 | PPP1R8 | Nuclear inhibitor of protein phosphatase 1 | [119] | 1.15[120] | 0.92[121] | 0.62[122] | 1.47[123] | 1.49[124] | -0.98[125] |
19 | PPP1R12C | Protein phosphatase 1 regulatory subunit 12C | [126] | 0.58[127] | 0.76[128] | 0.61[129] | 0.75[130] | 1.57[131] | -0.83[132] |
20 | PPP1R15B | Protein phosphatase 1 regulatory subunit 15B | [133] | 0.72[134] | 0.77[135] | 1.71[136] | 2.13[137] | 1.80[138] | 2.17[139] |
21 | MAP1LC3 | Microtubule-associated proteins 1A/1B light chain 3A | [140] | -8.51[141] | -10.27[142] | -9.77[143] | -2.53[144] | -0.46[145] | -0.75[146] |
22 | MAPK8 | Mitogen-activated protein kinase 8 | [147] | -0.92[148] | 0.19[149] | -1.08[150] | -0.20[151] | -0.21[152] | -0.33[153] |
23 | PPP1R2 | Protein phosphatase inhibitor 2 | [154] | 1.43[155] | 1.22[156] | 0.94[157] | 0.84[158] | 1.53[159] | 0.45[160] |
24 | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase | [161] | 0.21[162] | -0.14[163] | -2.25[164] | 1.72[165] | 1.36[166] | 0.97[167] |
25 | PPP1R3B | Protein phosphatase 1 regulatory subunit 3B | [168] | -2.10[169] | -3.07[170] | 1.00[171] | -0.62[172] | -0.43[173] | 3.86[174] |
26 | PPP1R10 | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | [175] | 1.89[176] | 0.99[177] | 1.16[178] | 1.64[179] | 1.90[180] | 1.25[181] |
27 | ATF6 | Cyclic AMP-dependent transcription factor ATF-6 alpha | [182] | 2.27[183] | 2.00[184] | 1.46[185] | 3.16[186] | 3.39[187] | 2.88[188] |
28 | PPP1R12A | Protein phosphatase 1 regulatory subunit 12A | [189] | 0.68[190] | 2.11[191] | 1.70[192] | 3.44[193] | 2.48[194] | 1.93[195] |
29 | PPP1R9B | Neurabin-2 | [196] | 2.37[197] | 1.42[198] | 2.02[199] | 2.37[200] | 2.72[201] | -0.54[202] |
30 | EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3 | [203] | 1.06[204] | 1.58[205] | 1.62[206] | 0.90[207] | 1.55[208] | 1.94[209] |
31 | MBTPS2 | Membrane-bound transcription factor site-2 protease | [210] | 1.47[211] | 1.52[212] | 2.17[213] | 2.80[214] | 2.83[215] | 1.74[216] |
32 | PPP1R1C | Protein phosphatase 1 regulatory subunit 1C | [217] | -2.04[218] | 0.58[219] | -0.40[220] | -3.82[221] | -3.79[222] | 0.03[223] |
33 | PPP1R13B | Apoptosis-stimulating of p53 protein 1 | [224] | 2.07[225] | 1.06[226] | 0.01[227] | 1.65[228] | 1.64[229] | 1.17[230] |
34 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | [231] | 0.35[232] | 0.63[233] | 0.48[234] | -0.27[235] | 1.19[236] | 2.35[237] |
35 | PPP1R12B | Protein phosphatase 1 regulatory subunit 12B | [238] | 2.61[239] | 3.16[240] | 3.42[241] | 4.72[242] | 3.74[243] | 4.77[244] |
36 | PPP1R3G | Protein phosphatase 1 regulatory subunit 3G | [245] | 0.67[246] | 1.46[247] | 0.64[248] | 0.13[249] | -1.48[250] | -0.92[251] |
37 | PPP1R14C | Protein phosphatase 1 regulatory subunit 14C | [252] | -4.91[253] | -5.28[254] | 2.52[255] | -3.11[256] | -1.11[257] | -6.33[258] |
38 | PPP1R14A | Protein phosphatase 1 regulatory subunit 14A | [259] | -4.98[260] | -6.26[261] | 2.18[262] | 0.82[263] | -2.72[264] | 1.79[265] |
39 | PPP1R9A | Neurabin-1 | [266] | 3.85[267] | 4.91[268] | 3.98[269] | 3.89[270] | -1.09[271] | 3.01[272] |
40 | PPP1R3D | Protein phosphatase 1 regulatory subunit 3D | [273] | 1.97[274] | 1.80[275] | 2.26[276] | 3.55[277] | 2.35[278] | 0.54[279] |
41 | PPP1R3F | Protein phosphatase 1 regulatory subunit 3F | [280] | -0.52[281] | -0.52[282] | 0.40[283] | 3.26[284] | 1.68[285] | 1.25[286] |
42 | BCL2 | Apoptosis regulator Bcl-2 | [287] | -2.33[288] | 2.77[289] | -4.77[290] | 2.48[291] | 2.32[292] | 3.42[293] |
43 | PPP1R16B | Protein phosphatase 1 regulatory inhibitor subunit 16B | [294] | -1.55[295] | -5.09[296] | -0.76[297] | -3.94[298] | -1.41[299] | 5.12[300] |
44 | PPP1R1B | Protein phosphatase 1 regulatory subunit 1B | [301] | -1.06[302] | -2.23[303] | -6.32[304] | -2.65[305] | 1.35[306] | -2.10[307] |
45 | PPP1R3E | Protein phosphatase 1 regulatory subunit 3E | [308] | [309] | [310] | [311] | [312] | [313] | [314] |
46 | PPP1R3A | Protein phosphatase 1 regulatory subunit 3A | [315] | [316] | [317] | [318] | [319] | [320] | [321] |
47 | PPP1R14D | Protein phosphatase 1 regulatory subunit 14D | [322] | [323] | [324] | [325] | [326] | [327] | [328] |