WP_ENDOMETRIAL_CANCER | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta | [1] | -4.73[2] | -5.07[3] | -4.08[4] | -4.01[5] | -3.05[6] | -2.25[7] |
2 | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha | [8] | -3.03[9] | -3.69[10] | -3.72[11] | -3.98[12] | -2.27[13] | -3.10[14] |
3 | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma | [15] | -10.48[16] | [17] | -8.75[18] | -7.83[19] | -7.78[20] | -1.81[21] |
4 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | [22] | 0.28[23] | -0.69[24] | -3.60[25] | -1.98[26] | 0.55[27] | -1.92[28] |
5 | FOS | Proto-oncogene c-Fos | [29] | -6.57[30] | -4.89[31] | -5.78[32] | -6.16[33] | -5.11[34] | -1.39[35] |
6 | AKT1 | RAC-alpha serine/threonine-protein kinase | [36] | -0.48[37] | -0.29[38] | -1.59[39] | -0.05[40] | -0.04[41] | -0.33[42] |
7 | CTNNB1 | Catenin beta-1 | [43] | 1.06[44] | 0.97[45] | 1.64[46] | 0.76[47] | 0.97[48] | 1.02[49] |
8 | ILK | Integrin-linked protein kinase | [50] | -1.36[51] | -1.00[52] | -1.30[53] | -0.45[54] | -1.36[55] | -1.54[56] |
9 | CTNNA1 | Catenin alpha-1 | [57] | 0.89[58] | 0.80[59] | 0.12[60] | 1.36[61] | 0.97[62] | 0.54[63] |
10 | MYC | Myc proto-oncogene protein | [64] | -0.13[65] | -0.05[66] | -2.30[67] | -2.79[68] | -0.43[69] | -2.08[70] |
11 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [71] | -1.49[72] | -1.40[73] | -1.04[74] | -0.54[75] | -0.05[76] | -1.28[77] |
12 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [78] | -0.51[79] | -0.41[80] | 0.24[81] | -0.84[82] | -0.37[83] | -1.79[84] |
13 | BAX | Apoptosis regulator BAX | [85] | -0.23[86] | -0.60[87] | -1.29[88] | -1.60[89] | -1.23[90] | -4.04[91] |
14 | CCND1 | G1/S-specific cyclin-D1 | [92] | 2.49[93] | 0.41[94] | 1.02[95] | 1.88[96] | 0.39[97] | 0.97[98] |
15 | GRB2 | Growth factor receptor-bound protein 2 | [99] | 0.64[100] | 0.89[101] | 0.79[102] | 0.56[103] | 0.45[104] | 0.21[105] |
16 | BAD | Bcl2-associated agonist of cell death | [106] | -2.23[107] | -1.68[108] | -2.85[109] | -1.06[110] | -0.68[111] | -1.51[112] |
17 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [113] | -0.62[114] | 0.20[115] | 1.25[116] | -0.18[117] | 0.66[118] | 1.01[119] |
18 | NRAS | GTPase NRas | [120] | 0.07[121] | 0.92[122] | 1.11[123] | 1.00[124] | 0.55[125] | -0.34[126] |
19 | ARAF | Serine/threonine-protein kinase A-Raf | [127] | -1.02[128] | -0.90[129] | -0.85[130] | -0.09[131] | -0.08[132] | 0.79[133] |
20 | CDH1 | Cadherin-1 | [134] | 0.56[135] | 1.46[136] | 1.77[137] | -3.16[138] | -7.44[139] | 1.48[140] |
21 | HRAS | GTPase HRas | [141] | -1.57[142] | -1.85[143] | -2.87[144] | -0.94[145] | -1.18[146] | -2.75[147] |
22 | MAPK1 | Mitogen-activated protein kinase 1 | [148] | 1.15[149] | 1.71[150] | 1.31[151] | 1.85[152] | 1.48[153] | 1.69[154] |
23 | AKT2 | RAC-beta serine/threonine-protein kinase | [155] | 0.40[156] | 1.10[157] | 1.00[158] | 0.86[159] | 0.63[160] | 1.05[161] |
24 | KRAS | GTPase KRas | [162] | -1.08[163] | -0.67[164] | 0.70[165] | 0.81[166] | 0.45[167] | 0.59[168] |
25 | FGFR3 | Fibroblast growth factor receptor 3 | [169] | 2.17[170] | 2.50[171] | 2.61[172] | -3.29[173] | -1.96[174] | 0.36[175] |
26 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [176] | -1.03[177] | -0.49[178] | 0.38[179] | 2.07[180] | 1.55[181] | 2.92[182] |
27 | SOS1 | Son of sevenless homolog 1 | [183] | -0.66[184] | 1.29[185] | 0.58[186] | 0.85[187] | 0.06[188] | 0.45[189] |
28 | ELK1 | ETS domain-containing protein Elk-1 | [190] | -0.88[191] | -2.59[192] | -0.39[193] | 0.28[194] | 0.85[195] | -0.25[196] |
29 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protei | -1.10[197] | 0.71[198] | 0.69[199] | -0.56[200] | 0.67[201] | 2.39[202] | |
30 | DDB2 | DNA damage-binding protein 2 | [203] | 0.52[204] | 0.46[205] | -1.07[206] | -1.60[207] | -1.04[208] | -1.61[209] |
31 | ERBB2 | Receptor tyrosine-protein kinase erbB-2 | [210] | 1.81[211] | 1.05[212] | 2.00[213] | 1.26[214] | 0.85[215] | 0.07[216] |
32 | BAK1 | Bcl-2 homologous antagonist/killer | [217] | 0.33[218] | 0.30[219] | 0.04[220] | 1.19[221] | 0.65[222] | -1.87[223] |
33 | EGFR | Epidermal growth factor receptor | [224] | -1.26[225] | -1.21[226] | 1.45[227] | 0.44[228] | 1.04[229] | 2.57[230] |
34 | TP53 | Cellular tumor antigen p53 | [231] | 1.08[232] | 1.06[233] | 1.60[234] | 1.30[235] | 0.94[236] | -0.13[237] |
35 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [238] | 1.31[239] | 1.96[240] | 2.34[241] | 0.71[242] | 1.25[243] | -0.38[244] |
36 | AXIN1 | Axin-1 | [245] | 0.79[246] | 1.53[247] | -0.26[248] | -8.69[249] | 0.14[250] | -0.74[251] |
37 | MAPK3 | Mitogen-activated protein kinase 3 | [252] | 1.29[253] | 1.76[254] | 1.57[255] | 0.43[256] | 0.43[257] | -1.13[258] |
38 | GSK3B | Glycogen synthase kinase-3 beta | [259] | 0.71[260] | 0.76[261] | 1.11[262] | 1.82[263] | 1.63[264] | 1.08[265] |
39 | FGF2 | Fibroblast growth factor 2 | [266] | -7.25[267] | -6.57[268] | -2.64[269] | 0.94[270] | 2.50[271] | -1.75[272] |
40 | AXIN2 | Axin-2 | [273] | 2.91[274] | 0.93[275] | -3.34[276] | -1.09[277] | -1.48[278] | -2.43[279] |
41 | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 | [280] | 1.77[281] | 3.38[282] | 1.87[283] | 1.44[284] | 1.82[285] | 2.42[286] |
42 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 0.65[287] | 1.58[288] | 1.52[289] | 1.05[290] | 1.19[291] | 1.07[292] | |
43 | FOXO3 | Forkhead box protein O3 | [293] | -0.11[294] | 0.40[295] | 0.82[296] | 0.41[297] | 1.62[298] | 2.25[299] |
44 | CASP9 | Caspase-9 | [300] | -0.40[301] | 0.98[302] | -0.13[303] | 0.25[304] | -0.45[305] | -0.62[306] |
45 | SOS2 | Son of sevenless homolog 2 | [307] | -0.59[308] | 0.96[309] | -0.03[310] | 1.69[311] | 1.54[312] | 1.76[313] |
46 | TCF7L2 | Transcription factor 7-like 2 | [314] | 0.31[315] | 1.49[316] | 1.47[317] | 0.70[318] | 0.66[319] | 1.64[320] |
47 | POLK | DNA polymerase kappa | [321] | -1.40[322] | 0.49[323] | 0.52[324] | 1.83[325] | 1.55[326] | 2.01[327] |
48 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -0.94[328] | 1.12[329] | 1.08[330] | 1.13[331] | 1.32[332] | 1.83[333] | |
49 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 1.33[334] | 2.83[335] | -1.20[336] | 0.28[337] | 1.03[338] | 0.21[339] | |
50 | TCF7L1 | Transcription factor 7-like 1 | [340] | -3.61[341] | -1.39[342] | 0.59[343] | -1.82[344] | -1.71[345] | 0.21[346] |
51 | TCF7 | Transcription factor 7 | [347] | 1.88[348] | 0.95[349] | -0.21[350] | 0.17[351] | -0.16[352] | -0.45[353] |
52 | FGFR2 | Fibroblast growth factor receptor 2 | [354] | -3.07[355] | -1.44[356] | 2.28[357] | 1.46[358] | -3.40[359] | 3.34[360] |
53 | APC | Adenomatous polyposis coli protein | [361] | 0.01[362] | 2.10[363] | 1.72[364] | 2.23[365] | 2.85[366] | 3.65[367] |
54 | BRAF | Serine/threonine-protein kinase B-raf | [368] | -0.31[369] | -0.16[370] | 1.65[371] | 0.75[372] | 0.42[373] | 1.77[374] |
55 | FGFR1 | Fibroblast growth factor receptor 1 | [375] | 4.02[376] | 2.75[377] | 4.18[378] | 5.06[379] | 4.31[380] | 1.58[381] |
56 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [382] | 1.16[383] | 1.59[384] | 2.22[385] | 3.17[386] | 2.17[387] | 2.59[388] |
57 | AKT3 | RAC-gamma serine/threonine-protein kinase | [389] | -2.40[390] | -4.54[391] | -4.07[392] | 5.85[393] | 4.78[394] | 3.52[395] |
58 | FGF1 | Fibroblast growth factor 1 | [396] | -3.33[397] | -2.11[398] | -6.80[399] | 0.59[400] | 2.15[401] | -0.04[402] |
59 | CTNNA3 | Catenin alpha-3 | [403] | -5.78[404] | [405] | [406] | -5.26[407] | -4.66[408] | 2.94[409] |
60 | LEF1 | Lymphoid enhancer-binding factor 1 | [410] | 2.09[411] | -4.41[412] | 3.28[413] | 1.09[414] | -0.64[415] | 1.00[416] |
61 | APC2 | Adenomatous polyposis coli protein 2 | [417] | 3.05[418] | 3.49[419] | 3.28[420] | 2.87[421] | 2.88[422] | 4.33[423] |
62 | CTNNA2 | Catenin alpha-2 | [424] | 0.24[425] | -2.29[426] | -3.64[427] | [428] | -2.95[429] | -0.32[430] |
63 | EGF | Pro-epidermal growth factor | [431] | 1.41[432] | 3.62[433] | 7.01[434] | 9.03[435] | 6.43[436] | 1.49[437] |