WP_ENDOCHONDRAL_OSSIFICATION_WITH_SKELETAL_DYSPLASIAS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CALM2 | Calmodulin-2 | [1] | -1.53[2] | -1.06[3] | -1.91[4] | -1.81[5] | -1.00[6] | -1.67[7] |
2 | HMGCS1 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | [8] | -3.83[9] | -0.99[10] | 1.03[11] | -4.34[12] | -4.08[13] | -0.20[14] |
3 | IGF2 | Insulin-like growth factor II | [15] | -2.99[16] | -1.28[17] | -3.43[18] | -13.48[19] | -11.08[20] | -6.97[21] |
4 | SLC38A2 | Sodium-coupled neutral amino acid transporter 2 | [22] | 0.91[23] | 2.15[24] | 0.24[25] | 0.06[26] | 1.12[27] | 1.50[28] |
5 | AKT1 | RAC-alpha serine/threonine-protein kinase | [29] | 0.06[30] | -0.57[31] | -1.02[32] | -0.11[33] | 0.42[34] | -0.20[35] |
6 | CALM1 | Calmodulin-1 | [36] | 0.06[37] | -0.30[38] | 0.78[39] | 1.53[40] | 1.31[41] | 1.66[42] |
7 | SPP1 | Osteopontin | [43] | 3.15[44] | 1.53[45] | -6.35[46] | 1.84[47] | -5.72[48] | -1.04[49] |
8 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [50] | -0.10[51] | -1.41[52] | 0.33[53] | 2.47[54] | 0.71[55] | 0.99[56] |
9 | IGF1 | Insulin-like growth factor I | [57] | -8.44[58] | -9.77[59] | -7.36[60] | -1.59[61] | -8.92[62] | 0.96[63] |
10 | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | [64] | -0.29[65] | -6.08[66] | -8.34[67] | -4.59[68] | -6.02[69] | 0.84[70] |
11 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | [71] | -0.19[72] | -0.75[73] | -0.13[74] | -0.52[75] | 0.57[76] | -0.74[77] |
12 | VEGFA | Vascular endothelial growth factor A | [78] | 1.20[79] | 2.14[80] | 1.37[81] | 0.38[82] | 1.60[83] | 0.82[84] |
13 | CAB39 | Calcium-binding protein 39 | [85] | -0.51[86] | -0.53[87] | 0.48[88] | 0.16[89] | 0.88[90] | 0.11[91] |
14 | GHR | Growth hormone receptor | [92] | -7.77[93] | -9.27[94] | -2.76[95] | -8.14[96] | -1.73[97] | 1.68[98] |
15 | SERPINH1 | Serpin H1 | [99] | 2.08[100] | 1.29[101] | 1.12[102] | 3.57[103] | 3.34[104] | -0.33[105] |
16 | TIMP3 | Metalloproteinase inhibitor 3 | [106] | 0.75[107] | 0.18[108] | 1.80[109] | -4.23[110] | -2.79[111] | 1.93[112] |
17 | FGFR3 | Fibroblast growth factor receptor 3 | [113] | 2.71[114] | 2.23[115] | 3.18[116] | -3.35[117] | -1.49[118] | 0.49[119] |
18 | SOX9 | Transcription factor SOX-9 | [120] | 2.34[121] | 2.08[122] | 2.55[123] | -0.99[124] | -1.23[125] | -3.09[126] |
19 | ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 | 0.98[127] | 1.64[128] | 2.23[129] | -0.27[130] | -2.03[131] | 2.93[132] | |
20 | FGF2 | Fibroblast growth factor 2 | [133] | -6.71[134] | -6.85[135] | -2.07[136] | 0.88[137] | 2.97[138] | -1.62[139] |
21 | STAT5B | Signal transducer and activator of transcription 5B | [140] | 1.34[141] | 0.57[142] | 1.90[143] | 1.50[144] | 1.14[145] | 1.67[146] |
22 | TGFB2 | Transforming growth factor beta-2 | [147] | -4.31[148] | -7.24[149] | -0.81[150] | 3.40[151] | 2.51[152] | -2.73[153] |
23 | IFT88 | Intraflagellar transport protein 88 homolog | [154] | -1.00[155] | 0.23[156] | 0.41[157] | 0.14[158] | 0.08[159] | 1.32[160] |
24 | BMPR1A | Bone morphogenetic protein receptor type-1A | [161] | 1.28[162] | 1.53[163] | 0.82[164] | 1.20[165] | 1.97[166] | 1.22[167] |
25 | TGFB1 | Transforming growth factor beta-1 | [168] | 3.45[169] | 2.02[170] | -0.10[171] | 3.78[172] | 3.52[173] | -1.19[174] |
26 | ADAMTS1 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | [175] | -3.20[176] | -7.45[177] | 1.71[178] | -1.37[179] | 2.60[180] | 2.19[181] |
27 | THRA | Thyroid hormone receptor alpha | [182] | 1.09[183] | -0.43[184] | 1.54[185] | 2.77[186] | 2.32[187] | 0.59[188] |
28 | PLAU | Urokinase-type plasminogen activator | [189] | 0.25[190] | -4.27[191] | -2.49[192] | 2.27[193] | 0.80[194] | -1.95[195] |
29 | KIF3A | Kinesin-like protein KIF3A | [196] | 0.62[197] | 1.26[198] | 0.81[199] | 2.07[200] | 2.31[201] | 0.42[202] |
30 | FGFR1 | Fibroblast growth factor receptor 1 | [203] | 4.56[204] | 2.48[205] | 4.75[206] | 5.00[207] | 4.78[208] | 1.70[209] |
31 | MMP9 | Matrix metalloproteinase-9 | [210] | -2.74[211] | -4.18[212] | -5.96[213] | -1.49[214] | -3.54[215] | -0.10[216] |
32 | IGF1R | Insulin-like growth factor 1 receptor | [217] | 4.72[218] | 3.64[219] | 2.93[220] | 4.42[221] | 4.47[222] | 2.13[223] |
33 | BMP6 | Bone morphogenetic protein 6 | [224] | 0.13[225] | -2.98[226] | -3.44[227] | -0.83[228] | -1.57[229] | 1.62[230] |
34 | SOX5 | Transcription factor SOX-5 | [231] | 1.90[232] | 1.73[233] | 3.04[234] | -2.08[235] | -1.69[236] | 4.22[237] |
35 | HDAC4 | Histone deacetylase 4 | [238] | 3.44[239] | 2.89[240] | 3.28[241] | 2.64[242] | 3.47[243] | 3.43[244] |
36 | MGP | Matrix Gla protein | [245] | -8.09[246] | [247] | -2.61[248] | 4.52[249] | 0.40[250] | 2.66[251] |
37 | ADAMTS4 | A disintegrin and metalloproteinase with thrombospondin motifs 4 | [252] | 2.81[253] | 2.79[254] | -1.78[255] | -0.98[256] | 0.83[257] | 1.85[258] |
38 | CDKN1C | Cyclin-dependent kinase inhibitor 1C | [259] | [260] | -5.67[261] | 1.65[262] | 1.11[263] | 0.99[264] | 1.50[265] |
39 | SOX6 | Transcription factor SOX-6 | [266] | -0.08[267] | 4.10[268] | 5.18[269] | -1.95[270] | -0.38[271] | 4.81[272] |
40 | PTCH1 | Protein patched homolog 1 | [273] | 2.61[274] | 2.46[275] | 4.45[276] | 3.27[277] | 3.12[278] | 2.89[279] |
41 | BMP7 | Bone morphogenetic protein 7 | [280] | -1.51[281] | -1.10[282] | -0.65[283] | -0.69[284] | -0.57[285] | -1.11[286] |
42 | IHH | Indian hedgehog protein | [287] | 1.03[288] | -1.31[289] | 5.13[290] | -4.35[291] | -4.71[292] | 0.14[293] |
43 | RUNX3 | Runt-related transcription factor 3 | [294] | 0.74[295] | -0.63[296] | 2.98[297] | 3.51[298] | -1.17[299] | 1.41[300] |
44 | SCIN | Adseverin | [301] | -3.79[302] | -3.79[303] | 2.37[304] | 2.27[305] | -1.42[306] | -1.03[307] |
45 | MEF2C | Myocyte-specific enhancer factor 2C | [308] | -3.13[309] | -2.40[310] | 3.19[311] | 5.56[312] | 2.05[313] | 5.33[314] |
46 | PLAT | Tissue-type plasminogen activator | [315] | 1.69[316] | 1.90[317] | -0.35[318] | 4.75[319] | 5.50[320] | 3.60[321] |
47 | COL2A1 | Collagen alpha-1(II) chain | [322] | 0.56[323] | 2.95[324] | 6.04[325] | -2.41[326] | -2.17[327] | [328] |
48 | CHST11 | Carbohydrate sulfotransferase 11 | [329] | 0.59[330] | -4.57[331] | 2.67[332] | 4.11[333] | 6.89[334] | 4.05[335] |
49 | PTHLH | Parathyroid hormone-related protein | [336] | 1.87[337] | 1.01[338] | -2.93[339] | 4.45[340] | 2.20[341] | [342] |
50 | DDR2 | Discoidin domain-containing receptor 2 | [343] | -0.86[344] | 3.27[345] | 2.28[346] | 8.40[347] | 8.25[348] | 5.24[349] |
51 | FRZB | Secreted frizzled-related protein 3 | [350] | -1.92[351] | 0.34[352] | 1.72[353] | 1.43[354] | 1.18[355] | 3.04[356] |
52 | RUNX2 | Runt-related transcription factor 2 | [357] | -0.87[358] | -1.62[359] | 4.07[360] | 7.07[361] | 9.53[362] | 3.67[363] |
53 | PTH1R | Parathyroid hormone/parathyroid hormone-related peptide receptor | -0.40[364] | [365] | -0.05[366] | -1.11[367] | 2.09[368] | 8.27[369] | |
54 | GLI3 | Transcriptional activator GLI3 | [370] | -1.25[371] | [372] | -0.06[373] | 8.88[374] | 7.75[375] | 4.20[376] |
55 | FGF18 | Fibroblast growth factor 18 | [377] | 1.76[378] | -2.75[379] | 0.04[380] | 0.56[381] | 1.66[382] | 0.63[383] |
56 | ADAMTS5 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | [384] | [385] | [386] | 3.23[387] | 3.51[388] | 10.56[389] | 9.99[390] |
57 | CST5 | Cystatin-D | [391] | [392] | [393] | [394] | [395] | [396] | [397] |
58 | MMP13 | Collagenase 3 | [398] | [399] | [400] | [401] | [402] | [403] | [404] |
59 | NKX3-2 | Homeobox protein Nkx-3.2 | [405] | [406] | [407] | [408] | [409] | [410] | [411] |
60 | MIR6073 | [412] | [413] | [414] | [415] | [416] | [417] | [418] | |
61 | ACAN | Aggrecan core protein | [419] | [420] | [421] | [422] | [423] | [424] | [425] |
62 | CTSV | Cathepsin L2 | [426] | [427] | [428] | [429] | [430] | [431] | [432] |
63 | GH1 | Somatotropin | [433] | [434] | [435] | [436] | [437] | [438] | [439] |
64 | COL10A1 | Collagen alpha-1(X) chain | [440] | [441] | [442] | [443] | [444] | [445] | [446] |
65 | PTH | Parathyroid hormone | [447] | [448] | [449] | [450] | [451] | [452] | [453] |