WP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CEBPB CCAAT/enhancer-binding protein beta [1] -1.60[2] -2.33[3] -2.80[4] -0.59[5] 0.07[6] -1.96[7]
2 CEBPA CCAAT/enhancer-binding protein alpha [8] -0.09[9] -1.39[10] 0.33[11] -6.20[12] -6.82[13] -0.32[14]
3 CEBPG CCAAT/enhancer-binding protein gamma [15] -0.36[16] -0.11[17] 0.53[18] -0.71[19] -0.08[20] 0.47[21]
4 MPZL2 Myelin protein zero-like protein 2 [22] -0.04[23] 2.10[24] 0.64[25] -5.08[26] -6.28[27] -0.84[28]
5 BMP2 Bone morphogenetic protein 2 [29] -5.40[30] -8.63[31] -0.04[32] -1.06[33] -1.09[34] -2.47[35]
6 SMAD1 Mothers against decapentaplegic homolog 1 [36] -1.47[37] -1.32[38] -1.52[39] 0.10[40] 0.38[41] 0.34[42]
7 PPARG Peroxisome proliferator-activated receptor gamma [43] -0.51[44] 1.00[45] 1.01[46] 1.67[47] 1.36[48] -0.67[49]
8 SMAD5 Mothers against decapentaplegic homolog 5 [50] 1.40[51] 2.00[52] 1.29[53] 3.47[54] 3.23[55] 2.67[56]
9 PPARGC1A Peroxisome proliferator-activated receptor gamma coactivator 1-alpha -1.51[57] 1.27[58] -10.00[59] 1.59[60] -1.99[61] 3.15[62]
10 BMP4 Bone morphogenetic protein 4 [63] 4.06[64] 3.19[65] -0.38[66] 2.83[67] 0.41[68] -1.47[69]
11 PLAC8 Placenta-specific gene 8 protein [70] 2.50[71] 2.57[72] 1.29[73] -0.05[74] 0.61[75] 0.71[76]
12 ZIC1 Zinc finger protein ZIC 1 [77] -5.75[78] -4.83[79] 2.59[80] -1.87[81] -4.16[82] -0.75[83]
13 SMAD9 Mothers against decapentaplegic homolog 9 [84] 3.56[85] 3.15[86] 1.91[87] 3.02[88] 4.26[89] 2.59[90]
14 BMP7 Bone morphogenetic protein 7 [91] -1.91[92] -1.21[93] -1.88[94] 0.19[95] -0.48[96] -1.44[97]
15 PPARGC1B Peroxisome proliferator-activated receptor gamma coactivator 1-beta 1.94[98] -2.08[99] 3.19[100] 3.49[101] 3.58[102] 4.65[103]
16 HOXC9 Homeobox protein Hox-C9 [104] 0.43[105] [106] 1.62[107] 4.08[108] 0.22[109] -6.18[110]
17 ADIPOQ Adiponectin [111] -1.94[112] -1.84[113] -2.57[114] -0.04[115] -1.32[116] -1.04[117]
18 ZNF423 Zinc finger protein 423 [118] 1.17[119] -4.43[120] -0.23[121] 2.27[122] -2.18[123] 3.19[124]
19 LEP Leptin [125] -1.75[126] -0.87[127] -1.91[128] -0.03[129] -1.63[130] 2.02[131]
20 PRDM16 PR domain zinc finger protein 16 [132] 2.70[133] -0.42[134] 6.60[135] 1.20[136] 0.36[137] 3.11[138]
21 HOXC8 Homeobox protein Hox-C8 [139] -0.40[140] -0.38[141] 4.54[142] 8.43[143] 5.92[144] -1.26[145]
22 EBF3 Transcription factor COE3 [146] [147] [148] [149] [150] [151] [152]
23 SLC7A10 Asc-type amino acid transporter 1 [153] [154] [155] [156] [157] [158] [159]
24 CIDEA Cell death activator CIDE-A [160] [161] [162] [163] [164] [165] [166]
25 HSPB7 Heat shock protein beta-7 [167] [168] [169] [170] [171] [172] [173]
[1]
ref_hepatocyte CEBPB
Mean 37.2
Standard deviation 25
Values 24 62 65 9 26
[2]
HepG2 CEBPB
Mean 36.4
Standard deviation 26
Values 18 55
[3]
HepG2.C3A CEBPB
Mean 20.9
Standard deviation 13
Values 12 30
[4]
HuH.7 CEBPB
Mean 20.5
Standard deviation 6.4
Values 23 25 13
[5]
SNU475 CEBPB
Mean 25.6
Standard deviation 11
Values 33 18
[6]
THLE CEBPB
Mean 55
Standard deviation 10
Values 48 62
[7]
liver CEBPB
Mean 16.5
Standard deviation 5.6
Values 22 16 18 9.1
[8]
ref_hepatocyte CEBPA
Mean 35.2
Standard deviation 31
Values 15 84 44 26 6.8
[9]
HepG2 CEBPA
Mean 98.2
Standard deviation 28
Values 78 1.2e+02
[10]
HepG2.C3A CEBPA
Mean 37.9
Standard deviation 7
Values 43 33
[11]
HuH.7 CEBPA
Mean 170
Standard deviation 21
Values 1.9e+02 1.7e+02 1.5e+02
[12]
SNU475 CEBPA
Mean 0.497
Standard deviation 0.0072
Values 0.5 0.49
[13]
THLE CEBPA
Mean 0.44
Standard deviation 0.15
Values 0.54 0.34
[14]
liver CEBPA
Mean 48.7
Standard deviation 19
Values 47 47 73 28
[15]
ref_hepatocyte CEBPG
Mean 16.1
Standard deviation 5.6
Values 15 7.1 21 21 16
[16]
HepG2 CEBPG
Mean 37.3
Standard deviation 8.2
Values 31 43
[17]
HepG2.C3A CEBPG
Mean 42.2
Standard deviation 12
Values 34 51
[18]
HuH.7 CEBPG
Mean 89.7
Standard deviation 16
Values 86 1.1e+02 76
[19]
SNU475 CEBPG
Mean 10.2
Standard deviation 1.8
Values 12 8.9
[20]
THLE CEBPG
Mean 21.5
Standard deviation 4.1
Values 24 19
[21]
liver CEBPG
Mean 38.8
Standard deviation 13
Values 29 28 57 41
[22]
ref_hepatocyte MPZL2
Mean 7.2
Standard deviation 6.8
Values 3 3.8 2.7 19 7.8
[23]
HepG2 MPZL2
Mean 20.8
Standard deviation 6.9
Values 26 16
[24]
HepG2.C3A MPZL2
Mean 87.4
Standard deviation 5.1
Values 84 91
[25]
HuH.7 MPZL2
Mean 43
Standard deviation 4.9
Values 41 49 40
[26]
SNU475 MPZL2
Mean 0.22
Standard deviation 0.069
Values 0.27 0.17
[27]
THLE MPZL2
Mean 0.13
Standard deviation 0.034
Values 0.15 0.11
[28]
liver MPZL2
Mean 6.96
Standard deviation 1.4
Values 6 5.6 8.5 7.7
[29]
ref_hepatocyte BMP2
Mean 5.74
Standard deviation 7.8
Values 11 0.28 0.49 0 17
[30]
HepG2 BMP2
Mean 0.401
Standard deviation 0.033
Values 0.42 0.38
[31]
HepG2.C3A BMP2
Mean 0.0409
Standard deviation 0.0028
Values 0.043 0.039
[32]
HuH.7 BMP2
Mean 21.5
Standard deviation 8.1
Values 17 31 17
[33]
SNU475 BMP2
Mean 2.85
Standard deviation 0.2
Values 2.7 3
[34]
THLE BMP2
Mean 3.79
Standard deviation 1.9
Values 2.4 5.2
[35]
liver BMP2
Mean 1.79
Standard deviation 0.56
Values 2.4 2.1 1.4 1.3
[36]
ref_hepatocyte SMAD1
Mean 5.73
Standard deviation 2
Values 6.7 7.5 7 2.8 4.6
[37]
HepG2 SMAD1
Mean 6.12
Standard deviation 1.6
Values 7.2 5
[38]
HepG2.C3A SMAD1
Mean 6.51
Standard deviation 0.83
Values 7.1 5.9
[39]
HuH.7 SMAD1
Mean 7.65
Standard deviation 2.8
Values 5.8 11 6.3
[40]
SNU475 SMAD1
Mean 6.35
Standard deviation 0.026
Values 6.3 6.4
[41]
THLE SMAD1
Mean 10.5
Standard deviation 1.5
Values 9.5 12
[42]
liver SMAD1
Mean 12.6
Standard deviation 5.3
Values 11 7.6 20 12
[43]
ref_hepatocyte PPARG
Mean 3.66
Standard deviation 0.37
Values 3.1 3.9 3.6 3.6 4.1
[44]
HepG2 PPARG
Mean 7.61
Standard deviation 0.54
Values 7.2 8
[45]
HepG2.C3A PPARG
Mean 20.7
Standard deviation 6.8
Values 16 26
[46]
HuH.7 PPARG
Mean 28.4
Standard deviation 6.2
Values 26 35 24
[47]
SNU475 PPARG
Mean 12.1
Standard deviation 2.4
Values 14 10
[48]
THLE PPARG
Mean 13.2
Standard deviation 1.2
Values 12 14
[49]
liver PPARG
Mean 4
Standard deviation 1.3
Values 2.5 4 3.8 5.7
[50]
ref_hepatocyte SMAD5
Mean 3.04
Standard deviation 1.1
Values 3.2 2.8 1.4 4.6 3.1
[51]
HepG2 SMAD5
Mean 23.8
Standard deviation 10
Values 31 16
[52]
HepG2.C3A SMAD5
Mean 34.5
Standard deviation 0.77
Values 34 35
[53]
HuH.7 SMAD5
Mean 28.5
Standard deviation 4.7
Values 24 33 28
[54]
SNU475 SMAD5
Mean 35
Standard deviation 2.7
Values 37 33
[55]
THLE SMAD5
Mean 40.3
Standard deviation 4
Values 43 37
[56]
liver SMAD5
Mean 33.5
Standard deviation 7
Values 42 35 31 26
[57]
ref_hepatocyte PPARGC1A
Mean 1.87
Standard deviation 1.7
Values 0.25 1.6 3.2 4 0.26
[58]
HepG2 PPARGC1A
Mean 1.94
Standard deviation 0.37
Values 2.2 1.7
[59]
HepG2.C3A PPARGC1A
Mean 12.8
Standard deviation 3.6
Values 10 15
[60]
HuH.7 PPARGC1A
Mean 0.00701
Standard deviation 0.0065
Values 0 0.013 0.0082
[61]
SNU475 PPARGC1A
Mean 5.83
Standard deviation 1.4
Values 4.9 6.8
[62]
THLE PPARGC1A
Mean 0.662
Standard deviation 0.1
Values 0.73 0.59
[63]
liver PPARGC1A
Mean 28.7
Standard deviation 18
Values 26 54 20 15
[64]
ref_hepatocyte BMP4
Mean 1.73
Standard deviation 3
Values 0 0.61 0.57 7.1 0.41
[65]
HepG2 BMP4
Mean 85.8
Standard deviation 17
Values 74 98
[66]
HepG2.C3A BMP4
Mean 44.8
Standard deviation 2.6
Values 43 47
[67]
HuH.7 BMP4
Mean 5.11
Standard deviation 0.75
Values 5.7 4.3 5.3
[68]
SNU475 BMP4
Mean 12.8
Standard deviation 5.7
Values 8.7 17
[69]
THLE BMP4
Mean 3.25
Standard deviation 0.32
Values 3 3.5
[70]
liver BMP4
Mean 1.08
Standard deviation 0.61
Values 0.65 0.47 1.6 1.6
[71]
ref_hepatocyte PLAC8
Mean 1.54
Standard deviation 1.2
Values 0.13 3.1 1.9 2.1 0.47
[72]
HepG2 PLAC8
Mean 26
Standard deviation 3.6
Values 23 29
[73]
HepG2.C3A PLAC8
Mean 25.9
Standard deviation 12
Values 34 18
[74]
HuH.7 PLAC8
Mean 14.5
Standard deviation 7.1
Values 20 6.6 17
[75]
SNU475 PLAC8
Mean 1.55
Standard deviation 0.38
Values 1.3 1.8
[76]
THLE PLAC8
Mean 3.33
Standard deviation 0.83
Values 3.9 2.7
[77]
liver PLAC8
Mean 4.36
Standard deviation 1.7
Values 2.5 3.4 5.8 5.8
[78]
ref_hepatocyte ZIC1
Mean 0.26
Standard deviation 0.24
Values 0.47 0.45 0.38 0 0
[79]
HepG2 ZIC1
Mean 0.0143
Standard deviation 0.004
Values 0.017 0.011
[80]
HepG2.C3A ZIC1
Mean 0.0258
Standard deviation 0.009
Values 0.032 0.019
[81]
HuH.7 ZIC1
Mean 5.98
Standard deviation 0.66
Values 6.7 5.5 5.7
[82]
SNU475 ZIC1
Mean 0.0739
Standard deviation 0.039
Values 0.1 0.046
[83]
THLE ZIC1
Mean 0.0204
Standard deviation 0.021
Values 0.035 0.0053
[84]
liver ZIC1
Mean 0.268
Standard deviation 0.39
Values 0.026 0.84 0 0.21
[85]
ref_hepatocyte SMAD9
Mean 0.23
Standard deviation 0.4
Values 0.11 0.081 0.026 0.93 0
[86]
HepG2 SMAD9
Mean 8.02
Standard deviation 1.2
Values 8.9 7.2
[87]
HepG2.C3A SMAD9
Mean 5.77
Standard deviation 0.67
Values 5.3 6.3
[88]
HuH.7 SMAD9
Mean 3.33
Standard deviation 1.9
Values 3.1 1.5 5.4
[89]
SNU475 SMAD9
Mean 1.93
Standard deviation 0.41
Values 1.6 2.2
[90]
THLE SMAD9
Mean 6.19
Standard deviation 0.49
Values 6.5 5.8
[91]
liver SMAD9
Mean 2.4
Standard deviation 0.36
Values 2.2 2.9 2 2.5
[92]
ref_hepatocyte BMP7
Mean 0.206
Standard deviation 0.045
Values 0.19 0.27 0.15 0.22 0.21
[93]
HepG2 BMP7
Mean 0.162
Standard deviation 0.019
Values 0.18 0.15
[94]
HepG2.C3A BMP7
Mean 0.253
Standard deviation 0.055
Values 0.21 0.29
[95]
HuH.7 BMP7
Mean 0.214
Standard deviation 0.051
Values 0.24 0.24 0.16
[96]
SNU475 BMP7
Mean 0.243
Standard deviation 0.036
Values 0.27 0.22
[97]
THLE BMP7
Mean 0.209
Standard deviation 0.039
Values 0.24 0.18
[98]
liver BMP7
Mean 0.131
Standard deviation 0.088
Values 0.16 0.24 0.047 0.077
[99]
ref_hepatocyte PPARGC1B
Mean 0.16
Standard deviation 0.12
Values 0.17 0.11 0.1 0.056 0.35
[100]
HepG2 PPARGC1B
Mean 1.82
Standard deviation 0.5
Values 1.5 2.2
[101]
HepG2.C3A PPARGC1B
Mean 0.107
Standard deviation 0.00023
Values 0.11 0.11
[102]
HuH.7 PPARGC1B
Mean 5.61
Standard deviation 1.8
Values 4.5 4.6 7.7
[103]
SNU475 PPARGC1B
Mean 1.86
Standard deviation 0.018
Values 1.9 1.9
[104]
THLE PPARGC1B
Mean 2.7
Standard deviation 0.41
Values 2.4 3
[105]
liver PPARGC1B
Mean 6.98
Standard deviation 1.2
Values 5.7 8.6 6.9 6.7
[106]
ref_hepatocyte HOXC9
Mean 0.138
Standard deviation 0.31
Values 0 0 0 0.69 0
[107]
HepG2 HOXC9
Mean 0.553
Standard deviation 0.061
Values 0.6 0.51
[108]
HepG2.C3A HOXC9
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 HOXC9
Mean 1.63
Standard deviation 0.18
Values 1.7 1.8 1.4
[110]
SNU475 HOXC9
Mean 2.42
Standard deviation 0.012
Values 2.4 2.4
[111]
THLE HOXC9
Mean 0.227
Standard deviation 0.0052
Values 0.23 0.22
[112]
liver HOXC9
Mean 0.00331
Standard deviation 0.0066
Values 0.013 0 0 0
[113]
ref_hepatocyte ADIPOQ
Mean 0.0714
Standard deviation 0.076
Values 0.073 0.041 0.2 0.045 0
[114]
HepG2 ADIPOQ
Mean 0.0551
Standard deviation 0.011
Values 0.047 0.063
[115]
HepG2.C3A ADIPOQ
Mean 0.0565
Standard deviation 0.011
Values 0.064 0.049
[116]
HuH.7 ADIPOQ
Mean 0.0463
Standard deviation 0.036
Values 0.075 0.0064 0.057
[117]
SNU475 ADIPOQ
Mean 0.0718
Standard deviation 0.049
Values 0.11 0.037
[118]
THLE ADIPOQ
Mean 0.0402
Standard deviation 0.027
Values 0.059 0.021
[119]
liver ADIPOQ
Mean 0.0603
Standard deviation 0.041
Values 0.093 0.071 0 0.077
[120]
ref_hepatocyte ZNF423
Mean 0.037
Standard deviation 0.036
Values 0.043 0.081 0.06 0 0
[121]
HepG2 ZNF423
Mean 0.247
Standard deviation 0.04
Values 0.22 0.28
[122]
HepG2.C3A ZNF423
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[123]
HuH.7 ZNF423
Mean 0.121
Standard deviation 0.036
Values 0.084 0.12 0.16
[124]
SNU475 ZNF423
Mean 0.185
Standard deviation 0.025
Values 0.2 0.17
[125]
THLE ZNF423
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[126]
liver ZNF423
Mean 0.584
Standard deviation 0.15
Values 0.77 0.64 0.52 0.41
[127]
ref_hepatocyte LEP
Mean 0.0195
Standard deviation 0.035
Values 0.016 0.081 0 0 0
[128]
HepG2 LEP
Mean 0.0172
Standard deviation 2.3e-05
Values 0.017 0.017
[129]
HepG2.C3A LEP
Mean 0.0302
Standard deviation 0.012
Values 0.021 0.039
[130]
HuH.7 LEP
Mean 0.0199
Standard deviation 0.0091
Values 0.0094 0.026 0.025
[131]
SNU475 LEP
Mean 0.0198
Standard deviation 0.015
Values 0.03 0.0093
[132]
THLE LEP
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[133]
liver LEP
Mean 0.137
Standard deviation 0.14
Values 0.25 0.27 0 0.026
[134]
ref_hepatocyte PRDM16
Mean 0.014
Standard deviation 0.016
Values 0 0 0.017 0.04 0.013
[135]
HepG2 PRDM16
Mean 0.27
Standard deviation 0.097
Values 0.2 0.34
[136]
HepG2.C3A PRDM16
Mean 0.0297
Standard deviation 0.027
Values 0.011 0.049
[137]
HuH.7 PRDM16
Mean 5.23
Standard deviation 0.95
Values 4.3 5.2 6.2
[138]
SNU475 PRDM16
Mean 0.0333
Standard deviation 0.018
Values 0.02 0.046
[139]
THLE PRDM16
Mean 0.0254
Standard deviation 0.0059
Values 0.03 0.021
[140]
liver PRDM16
Mean 0.21
Standard deviation 0.11
Values 0.28 0.13 0.33 0.1
[141]
ref_hepatocyte HOXC8
Mean 0.00984
Standard deviation 0.022
Values 0 0 0 0 0.049
[142]
HepG2 HOXC8
Mean 0.0222
Standard deviation 0.001
Values 0.021 0.023
[143]
HepG2.C3A HOXC8
Mean 0.0215
Standard deviation 0.03
Values 0.043 0
[144]
HuH.7 HOXC8
Mean 0.876
Standard deviation 0.097
Values 0.8 0.85 0.98
[145]
SNU475 HOXC8
Mean 3.53
Standard deviation 0.51
Values 3.9 3.2
[146]
THLE HOXC8
Mean 0.839
Standard deviation 0.2
Values 0.98 0.7
[147]
liver HOXC8
Mean 0.00713
Standard deviation 0.014
Values 0 0.029 0 0
[148]
ref_hepatocyte EBF3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 EBF3
Mean 0.0186
Standard deviation 0.014
Values 0.0086 0.029
[150]
HepG2.C3A EBF3
Mean 0.0447
Standard deviation 0.033
Values 0.021 0.068
[151]
HuH.7 EBF3
Mean 0.514
Standard deviation 0.17
Values 0.39 0.71 0.44
[152]
SNU475 EBF3
Mean 0.0373
Standard deviation 0.046
Values 0.0051 0.07
[153]
THLE EBF3
Mean 0.00828
Standard deviation 0.0033
Values 0.0059 0.011
[154]
liver EBF3
Mean 0.214
Standard deviation 0.27
Values 0.6 0.071 0.19 0
[155]
ref_hepatocyte SLC7A10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[156]
HepG2 SLC7A10
Mean 0.104
Standard deviation 0.032
Values 0.082 0.13
[157]
HepG2.C3A SLC7A10
Mean 0.217
Standard deviation 0.064
Values 0.17 0.26
[158]
HuH.7 SLC7A10
Mean 9.27
Standard deviation 1.1
Values 11 8.4 8.9
[159]
SNU475 SLC7A10
Mean 0.476
Standard deviation 0.26
Values 0.29 0.66
[160]
THLE SLC7A10
Mean 0.0497
Standard deviation 0.055
Values 0.089 0.011
[161]
liver SLC7A10
Mean 0.0165
Standard deviation 0.033
Values 0.066 0 0 0
[162]
ref_hepatocyte CIDEA
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 CIDEA
Mean 0.0637
Standard deviation 0.072
Values 0.013 0.11
[164]
HepG2.C3A CIDEA
Mean 0
Standard deviation 0
Values 0 0
[165]
HuH.7 CIDEA
Mean 0
Standard deviation 0
Values 0 0 0
[166]
SNU475 CIDEA
Mean 0.0101
Standard deviation 0.014
Values 0.02 0
[167]
THLE CIDEA
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[168]
liver CIDEA
Mean 0
Standard deviation 0
Values 0 0 0 0
[169]
ref_hepatocyte HSPB7
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[170]
HepG2 HSPB7
Mean 0.599
Standard deviation 0.32
Values 0.37 0.83
[171]
HepG2.C3A HSPB7
Mean 0.0565
Standard deviation 0.011
Values 0.064 0.049
[172]
HuH.7 HSPB7
Mean 0.0387
Standard deviation 0.042
Values 0 0.083 0.033
[173]
SNU475 HSPB7
Mean 0.701
Standard deviation 0.041
Values 0.73 0.67
[174]
THLE HSPB7
Mean 6.87
Standard deviation 3.9
Values 4.1 9.6
[175]
liver HSPB7
Mean 0.243
Standard deviation 0.19
Values 0.25 0.043 0.19 0.49