WP_DEGRADATION_PATHWAY_OF_SPHINGOLIPIDS_INCLUDING_DISEASES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 NEU1 Sialidase-1 [1] 0.21[2] -0.01[3] -1.12[4] -1.00[5] -1.40[6] -1.22[7]
2 HEXB Beta-hexosaminidase subunit beta [8] -0.94[9] -0.94[10] -0.14[11] -0.29[12] 0.20[13] 0.07[14]
3 GLB1 Beta-galactosidase [15] -0.05[16] -0.03[17] 1.25[18] -0.06[19] 0.44[20] 0.50[21]
4 HEXA Beta-hexosaminidase subunit alpha [22] 0.73[23] 0.45[24] 0.38[25] 1.32[26] 0.95[27] 0.63[28]
5 NEU4 Sialidase-4 [29] 0.09[30] 1.42[31] -7.98[32] -5.20[33] -8.26[34] 0.23[35]
6 GLA Alpha-galactosidase A [36] -0.78[37] -1.04[38] 0.35[39] 0.65[40] 0.17[41] -1.17[42]
7 GM2A Ganglioside GM2 activator [43] 0.35[44] -0.11[45] 0.22[46] 0.44[47] 0.82[48] 0.13[49]
8 ARSA Arylsulfatase A [50] 0.15[51] -0.04[52] 0.60[53] 0.58[54] -0.17[55] 1.10[56]
9 NEU3 Sialidase-3 [57] 2.24[58] 1.93[59] 1.75[60] 2.46[61] 2.31[62] 2.87[63]
10 NEU2 Sialidase-2 [64] [65] [66] [67] [68] [69] [70]
[1]
ref_hepatocyte NEU1
Mean 37.6
Standard deviation 42
Values 16 19 24 1.1e+02 16
[2]
HepG2 NEU1
Mean 157
Standard deviation 34
Values 1.8e+02 1.3e+02
[3]
HepG2.C3A NEU1
Mean 91.4
Standard deviation 4.1
Values 94 89
[4]
HuH.7 NEU1
Mean 34.6
Standard deviation 13
Values 32 49 24
[5]
SNU475 NEU1
Mean 25.2
Standard deviation 0.97
Values 25 26
[6]
THLE NEU1
Mean 26.2
Standard deviation 7.6
Values 21 32
[7]
liver NEU1
Mean 17.6
Standard deviation 6.7
Values 12 12 25 21
[8]
ref_hepatocyte HEXB
Mean 33.9
Standard deviation 11
Values 16 38 44 39 33
[9]
HepG2 HEXB
Mean 64.1
Standard deviation 5.9
Values 60 68
[10]
HepG2.C3A HEXB
Mean 43.4
Standard deviation 2.1
Values 42 45
[11]
HuH.7 HEXB
Mean 61.5
Standard deviation 15
Values 61 77 46
[12]
SNU475 HEXB
Mean 37.4
Standard deviation 0.5
Values 38 37
[13]
THLE HEXB
Mean 71.3
Standard deviation 17
Values 59 83
[14]
liver HEXB
Mean 39
Standard deviation 15
Values 22 34 42 57
[15]
ref_hepatocyte GLB1
Mean 15.3
Standard deviation 5.7
Values 8.6 18 18 22 9.9
[16]
HepG2 GLB1
Mean 53.1
Standard deviation 4.7
Values 50 56
[17]
HepG2.C3A GLB1
Mean 36.7
Standard deviation 8.2
Values 31 42
[18]
HuH.7 GLB1
Mean 72.4
Standard deviation 9.9
Values 75 81 62
[19]
SNU475 GLB1
Mean 19.7
Standard deviation 1.4
Values 21 19
[20]
THLE GLB1
Mean 38.2
Standard deviation 4.9
Values 35 42
[21]
liver GLB1
Mean 23.6
Standard deviation 8.2
Values 16 20 23 35
[22]
ref_hepatocyte HEXA
Mean 15.3
Standard deviation 8.5
Values 6.1 24 25 11 11
[23]
HepG2 HEXA
Mean 91.6
Standard deviation 1.4
Values 91 93
[24]
HepG2.C3A HEXA
Mean 51.3
Standard deviation 2.1
Values 50 53
[25]
HuH.7 HEXA
Mean 39.8
Standard deviation 6.4
Values 47 35 37
[26]
SNU475 HEXA
Mean 51.2
Standard deviation 9
Values 45 58
[27]
THLE HEXA
Mean 54.1
Standard deviation 9.1
Values 48 61
[28]
liver HEXA
Mean 25.8
Standard deviation 15
Values 12 17 28 46
[29]
ref_hepatocyte NEU4
Mean 9.26
Standard deviation 7.7
Values 1.6 10 15 18 1.2
[30]
HepG2 NEU4
Mean 35.6
Standard deviation 16
Values 47 24
[31]
HepG2.C3A NEU4
Mean 60.8
Standard deviation 15
Values 50 71
[32]
HuH.7 NEU4
Mean 0.0735
Standard deviation 0.036
Values 0.037 0.11 0.074
[33]
SNU475 NEU4
Mean 0.338
Standard deviation 0.027
Values 0.32 0.36
[34]
THLE NEU4
Mean 0.0553
Standard deviation 0.056
Values 0.095 0.016
[35]
liver NEU4
Mean 11.8
Standard deviation 4.7
Values 17 8.3 14 7.5
[36]
ref_hepatocyte GLA
Mean 9.06
Standard deviation 4.8
Values 7.9 3.7 16 5.9 12
[37]
HepG2 GLA
Mean 19.1
Standard deviation 1.1
Values 20 18
[38]
HepG2.C3A GLA
Mean 10.8
Standard deviation 4.5
Values 14 7.6
[39]
HuH.7 GLA
Mean 23.1
Standard deviation 7.4
Values 31 17 22
[40]
SNU475 GLA
Mean 19.1
Standard deviation 7.5
Values 24 14
[41]
THLE GLA
Mean 18.7
Standard deviation 1.1
Values 18 19
[42]
liver GLA
Mean 4.39
Standard deviation 1.9
Values 2.4 3.8 4.5 6.9
[43]
ref_hepatocyte GM2A
Mean 7.5
Standard deviation 4.8
Values 1.5 7.5 5 15 8.9
[44]
HepG2 GM2A
Mean 34.4
Standard deviation 5.9
Values 39 30
[45]
HepG2.C3A GM2A
Mean 17
Standard deviation 3
Values 19 15
[46]
HuH.7 GM2A
Mean 17.4
Standard deviation 1.2
Values 16 18 18
[47]
SNU475 GM2A
Mean 13.6
Standard deviation 3.6
Values 11 16
[48]
THLE GM2A
Mean 24.2
Standard deviation 3.2
Values 22 26
[49]
liver GM2A
Mean 8.95
Standard deviation 1.6
Values 8.7 9.3 6.9 11
[50]
ref_hepatocyte ARSA
Mean 4.57
Standard deviation 3.9
Values 1.1 11 6.3 3 2
[51]
HepG2 ARSA
Mean 18.3
Standard deviation 1.7
Values 17 19
[52]
HepG2.C3A ARSA
Mean 10.9
Standard deviation 3.9
Values 8.2 14
[53]
HuH.7 ARSA
Mean 13.8
Standard deviation 0.71
Values 14 13 14
[54]
SNU475 ARSA
Mean 9.16
Standard deviation 3.8
Values 6.5 12
[55]
THLE ARSA
Mean 7.43
Standard deviation 0.15
Values 7.3 7.5
[56]
liver ARSA
Mean 10.7
Standard deviation 8.6
Values 5.3 3.6 23 11
[57]
ref_hepatocyte NEU3
Mean 0.388
Standard deviation 0.39
Values 0.13 0.18 0.052 0.6 0.98
[58]
HepG2 NEU3
Mean 6.6
Standard deviation 2.3
Values 8.2 5
[59]
HepG2.C3A NEU3
Mean 3.64
Standard deviation 1.5
Values 4.7 2.6
[60]
HuH.7 NEU3
Mean 2.6
Standard deviation 1.2
Values 2 1.8 4
[61]
SNU475 NEU3
Mean 2.87
Standard deviation 0.21
Values 2.7 3
[62]
THLE NEU3
Mean 3.52
Standard deviation 0.5
Values 3.2 3.9
[63]
liver NEU3
Mean 3.09
Standard deviation 2.5
Values 5.4 5.2 0.99 0.85
[64]
ref_hepatocyte NEU2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 NEU2
Missing
[66]
HepG2.C3A NEU2
Missing
[67]
HuH.7 NEU2
Missing
[68]
SNU475 NEU2
Missing
[69]
THLE NEU2
Missing
[70]
liver NEU2
Missing