WP_COVID19_ADVERSE_OUTCOME_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AGT Angiotensinogen [1] 0.08[2] 0.11[3] 0.09[4] -0.49[5] -8.60[6] 0.10[7]
2 CCL2 C-C motif chemokine 2 [8] -11.49[9] [10] -10.27[11] 2.00[12] 1.13[13] -5.44[14]
3 TMPRSS2 Transmembrane protease serine 2 [15] -0.30[16] -6.36[17] -3.41[18] -4.14[19] -5.41[20] -1.85[21]
4 CCL3 C-C motif chemokine 3 [22] [23] [24] [25] -2.07[26] [27] -6.17[28]
5 IL1B Interleukin-1 beta [29] -6.79[30] -7.58[31] -1.69[32] 2.53[33] 5.08[34] -6.95[35]
6 CSF3 Granulocyte colony-stimulating factor [36] -0.27[37] -4.80[38] -3.64[39] -0.82[40] 7.53[41] -9.17[42]
7 CXCL10 C-X-C motif chemokine 10 [43] -7.24[44] -5.86[45] 0.83[46] 4.56[47] -6.07[48] -4.13[49]
8 IL6 Interleukin-6 [50] -6.54[51] [52] -2.28[53] 5.27[54] 4.74[55] [56]
9 IL7 Interleukin-7 [57] -0.75[58] -0.20[59] -4.24[60] 0.32[61] 0.91[62] -0.45[63]
10 IL10 Interleukin-10 [64] 0.03[65] -1.14[66] 0.61[67] 4.14[68] 0.63[69] -3.34[70]
11 ACE2 Angiotensin-converting enzyme 2 [71] 1.59[72] 2.01[73] 2.61[74] -0.89[75] -3.34[76] -1.83[77]
12 IL2RA Interleukin-2 receptor subunit alpha [78] [79] -4.61[80] [81] 1.52[82] -3.43[83] -1.22[84]
13 TNF Tumor necrosis factor [85] 3.00[86] -0.05[87] -3.08[88] 3.90[89] -2.37[90] -3.64[91]
14 CXCL8 Interleukin-8 [92] [93] [94] [95] [96] [97] [98]
15 IL2 Interleukin-2 [99] [100] [101] [102] [103] [104] [105]
[1]
ref_hepatocyte AGT
Mean 439
Standard deviation 4.5e+02
Values 77 7e+02 1.1e+03 3.3e+02 6.7
[2]
HepG2 AGT
Mean 273
Standard deviation 17
Values 2.9e+02 2.6e+02
[3]
HepG2.C3A AGT
Mean 471
Standard deviation 99
Values 4e+02 5.4e+02
[4]
HuH.7 AGT
Mean 150
Standard deviation 28
Values 1.4e+02 1.8e+02 1.3e+02
[5]
SNU475 AGT
Mean 8.25
Standard deviation 2.2
Values 9.8 6.7
[6]
THLE AGT
Mean 0.276
Standard deviation 0.11
Values 0.35 0.2
[7]
liver AGT
Mean 2.25e+03
Standard deviation 2.3e+03
Values 6.1e+02 6.9e+02 5.5e+03 2.2e+03
[8]
ref_hepatocyte CCL2
Mean 10.5
Standard deviation 21
Values 47 0.22 2.1 0 2.9
[9]
HepG2 CCL2
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[10]
HepG2.C3A CCL2
Mean 0
Standard deviation 0
Values 0 0
[11]
HuH.7 CCL2
Mean 0.00273
Standard deviation 0.0047
Values 0 0 0.0082
[12]
SNU475 CCL2
Mean 1.11
Standard deviation 0.87
Values 1.7 0.49
[13]
THLE CCL2
Mean 5.56
Standard deviation 0.79
Values 5 6.1
[14]
liver CCL2
Mean 1.15
Standard deviation 1.1
Values 0.4 0.19 2.6 1.4
[15]
ref_hepatocyte TMPRSS2
Mean 9.87
Standard deviation 16
Values 39 2.3 5.7 0.7 1.8
[16]
HepG2 TMPRSS2
Mean 4.74
Standard deviation 2.3
Values 6.4 3.1
[17]
HepG2.C3A TMPRSS2
Mean 0.12
Standard deviation 0.064
Values 0.075 0.17
[18]
HuH.7 TMPRSS2
Mean 0.299
Standard deviation 0.14
Values 0.42 0.15 0.32
[19]
SNU475 TMPRSS2
Mean 0.0148
Standard deviation 0.0078
Values 0.02 0.0093
[20]
THLE TMPRSS2
Mean 0.0565
Standard deviation 0.012
Values 0.065 0.048
[21]
liver TMPRSS2
Mean 13.1
Standard deviation 5.1
Values 17 15 5.8 14
[22]
ref_hepatocyte CCL3
Mean 6.04
Standard deviation 8.1
Values 20 3.5 7.1 0 0
[23]
HepG2 CCL3
Mean 0
Standard deviation 0
Values 0 0
[24]
HepG2.C3A CCL3
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 CCL3
Mean 0
Standard deviation 0
Values 0 0 0
[26]
SNU475 CCL3
Mean 0.038
Standard deviation 0.025
Values 0.02 0.056
[27]
THLE CCL3
Mean 0
Standard deviation 0
Values 0 0
[28]
liver CCL3
Mean 0.402
Standard deviation 0.41
Values 0.15 0.086 0.4 0.98
[29]
ref_hepatocyte IL1B
Mean 3.09
Standard deviation 5.4
Values 13 0.76 2 0 0.08
[30]
HepG2 IL1B
Mean 0.0165
Standard deviation 0.017
Values 0.0043 0.029
[31]
HepG2.C3A IL1B
Mean 0.0161
Standard deviation 0.023
Values 0.032 0
[32]
HuH.7 IL1B
Mean 0.309
Standard deviation 0.06
Values 0.3 0.37 0.25
[33]
SNU475 IL1B
Mean 0.472
Standard deviation 0.21
Values 0.62 0.32
[34]
THLE IL1B
Mean 25.4
Standard deviation 8.5
Values 31 19
[35]
liver IL1B
Mean 0.12
Standard deviation 0.051
Values 0.17 0.11 0.14 0.051
[36]
ref_hepatocyte CSF3
Mean 1.66
Standard deviation 3.7
Values 8.3 0 0 0 0
[37]
HepG2 CSF3
Mean 0.813
Standard deviation 0.63
Values 0.36 1.3
[38]
HepG2.C3A CSF3
Mean 0.0593
Standard deviation 0.054
Values 0.021 0.097
[39]
HuH.7 CSF3
Mean 0.0429
Standard deviation 0.021
Values 0.037 0.026 0.066
[40]
SNU475 CSF3
Mean 0.0247
Standard deviation 0.015
Values 0.035 0.014
[41]
THLE CSF3
Mean 74.8
Standard deviation 28
Values 95 55
[42]
liver CSF3
Mean 0.0138
Standard deviation 0.016
Values 0.026 0.029 0 0
[43]
ref_hepatocyte CXCL10
Mean 1.47
Standard deviation 1.4
Values 1 3.6 0.71 0 2
[44]
HepG2 CXCL10
Mean 0.00573
Standard deviation 0.0081
Values 0 0.011
[45]
HepG2.C3A CXCL10
Mean 0.0253
Standard deviation 0.0055
Values 0.021 0.029
[46]
HuH.7 CXCL10
Mean 0.841
Standard deviation 0.64
Values 0.49 1.6 0.45
[47]
SNU475 CXCL10
Mean 0.916
Standard deviation 0.53
Values 0.54 1.3
[48]
THLE CXCL10
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[49]
liver CXCL10
Mean 0.401
Standard deviation 0.27
Values 0.16 0.2 0.71 0.54
[50]
ref_hepatocyte IL6
Mean 1.35
Standard deviation 2.5
Values 5.9 0.28 0.6 0 0
[51]
HepG2 IL6
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[52]
HepG2.C3A IL6
Mean 0
Standard deviation 0
Values 0 0
[53]
HuH.7 IL6
Mean 0.0895
Standard deviation 0.012
Values 0.1 0.083 0.082
[54]
SNU475 IL6
Mean 1.37
Standard deviation 1.7
Values 2.6 0.15
[55]
THLE IL6
Mean 8.81
Standard deviation 1.5
Values 7.7 9.9
[56]
liver IL6
Mean 0
Standard deviation 0
Values 0 0 0 0
[57]
ref_hepatocyte IL7
Mean 1.1
Standard deviation 0.7
Values 1.1 2.2 1.1 1 0.18
[58]
HepG2 IL7
Mean 0.386
Standard deviation 0.18
Values 0.51 0.26
[59]
HepG2.C3A IL7
Mean 0.954
Standard deviation 0.44
Values 1.3 0.64
[60]
HuH.7 IL7
Mean 0.0187
Standard deviation 0.017
Values 0.0094 0.039 0.0082
[61]
SNU475 IL7
Mean 0.0363
Standard deviation 0.0011
Values 0.035 0.037
[62]
THLE IL7
Mean 0.502
Standard deviation 0.13
Values 0.41 0.6
[63]
liver IL7
Mean 3.86
Standard deviation 1.5
Values 5.3 2.8 4.9 2.4
[64]
ref_hepatocyte IL10
Mean 0.495
Standard deviation 0.35
Values 0.95 0.36 0.6 0 0.57
[65]
HepG2 IL10
Mean 0.299
Standard deviation 0.17
Values 0.18 0.42
[66]
HepG2.C3A IL10
Mean 0.224
Standard deviation 0.14
Values 0.32 0.13
[67]
HuH.7 IL10
Mean 0.243
Standard deviation 0.091
Values 0.16 0.34 0.23
[68]
SNU475 IL10
Mean 0.23
Standard deviation 0.0042
Values 0.23 0.23
[69]
THLE IL10
Mean 0.187
Standard deviation 0.022
Values 0.17 0.2
[70]
liver IL10
Mean 0.233
Standard deviation 0.024
Values 0.25 0.21 0.21 0.26
[71]
ref_hepatocyte ACE2
Mean 0.357
Standard deviation 0.39
Values 0 0.41 0.21 0.17 1
[72]
HepG2 ACE2
Mean 0.635
Standard deviation 0.46
Values 0.96 0.31
[73]
HepG2.C3A ACE2
Mean 1.43
Standard deviation 0.89
Values 2.1 0.81
[74]
HuH.7 ACE2
Mean 0.702
Standard deviation 0.38
Values 0.47 1.1 0.5
[75]
SNU475 ACE2
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[76]
THLE ACE2
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[77]
liver ACE2
Mean 0.481
Standard deviation 0.28
Values 0.34 0.9 0.4 0.28
[78]
ref_hepatocyte IL2RA
Mean 0.131
Standard deviation 0.1
Values 0.19 0.057 0 0.15 0.26
[79]
HepG2 IL2RA
Mean 0
Standard deviation 0
Values 0 0
[80]
HepG2.C3A IL2RA
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[81]
HuH.7 IL2RA
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 IL2RA
Mean 0.00992
Standard deviation 0.0075
Values 0.015 0.0046
[83]
THLE IL2RA
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[84]
liver IL2RA
Mean 0.27
Standard deviation 0.33
Values 0.75 0.2 0.024 0.1
[85]
ref_hepatocyte TNF
Mean 0.113
Standard deviation 0.17
Values 0 0.39 0.17 0 0
[86]
HepG2 TNF
Mean 0.533
Standard deviation 0.44
Values 0.22 0.84
[87]
HepG2.C3A TNF
Mean 0.108
Standard deviation 0.029
Values 0.13 0.087
[88]
HuH.7 TNF
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[89]
SNU475 TNF
Mean 0.0443
Standard deviation 0.023
Values 0.061 0.028
[90]
THLE TNF
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[91]
liver TNF
Mean 0.0431
Standard deviation 0.06
Values 0.13 0.014 0 0.026
[92]
ref_hepatocyte CXCL8
Missing
[93]
HepG2 CXCL8
Missing
[94]
HepG2.C3A CXCL8
Missing
[95]
HuH.7 CXCL8
Missing
[96]
SNU475 CXCL8
Missing
[97]
THLE CXCL8
Missing
[98]
liver CXCL8
Missing
[99]
ref_hepatocyte IL2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 IL2
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A IL2
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 IL2
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 IL2
Mean 0.00464
Standard deviation 0.0066
Values 0 0.0093
[104]
THLE IL2
Mean 0
Standard deviation 0
Values 0 0
[105]
liver IL2
Mean 0.00918
Standard deviation 0.011
Values 0.013 0 0.024 0