WP_CONGENITAL_GENERALIZED_LIPODYSTROPHY_CGL Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [1] -2.28[2] -1.94[3] -1.99[4] -3.48[5] -2.98[6] -0.65[7]
2 DGAT2 Diacylglycerol O-acyltransferase 2 [8] -0.45[9] -1.34[10] -2.54[11] -4.95[12] -3.62[13] 0.03[14]
3 HIF1A Hypoxia-inducible factor 1-alpha [15] 0.06[16] -0.29[17] 0.21[18] 1.86[19] 2.23[20] -1.26[21]
4 CAV1 Caveolin-1 [22] -6.62[23] -9.46[24] -3.49[25] 0.95[26] -0.41[27] -2.45[28]
5 GRB2 Growth factor receptor-bound protein 2 [29] 1.41[30] 1.23[31] 1.05[32] 0.13[33] 0.03[34] -0.16[35]
6 AKT2 RAC-beta serine/threonine-protein kinase [36] 1.18[37] 1.43[38] 1.26[39] 0.43[40] 0.21[41] 0.67[42]
7 BSCL2 Seipin [43] -5.31[44] -4.61[45] -5.79[46] -5.44[47] -4.47[48] -4.70[49]
8 LPIN2 Phosphatidate phosphatase LPIN2 [50] 1.34[51] 1.95[52] 2.30[53] 0.34[54] -0.15[55] 2.17[56]
9 LPIN1 Phosphatidate phosphatase LPIN1 [57] -1.37[58] 0.44[59] -0.94[60] 0.09[61] -0.85[62] 0.99[63]
10 DGAT1 Diacylglycerol O-acyltransferase 1 [64] 1.53[65] 1.34[66] 1.53[67] -0.76[68] -0.91[69] -0.26[70]
11 IRS1 Insulin receptor substrate 1 [71] 2.31[72] 1.73[73] 2.86[74] 1.28[75] 0.85[76] 1.66[77]
12 FYN Tyrosine-protein kinase Fyn [78] 1.16[79] -7.46[80] 0.80[81] 1.04[82] 2.56[83] 0.51[84]
13 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -0.16[85] 1.46[86] 1.34[87] 0.70[88] 0.90[89] 1.46[90]
14 LPIN3 Phosphatidate phosphatase LPIN3 [91] 1.79[92] 2.79[93] 0.60[94] 0.98[95] 0.56[96] 3.21[97]
15 ITGB4 Integrin beta-4 [98] 5.93[99] 5.98[100] 2.13[101] 3.74[102] 1.58[103] 2.35[104]
16 INS Insulin [105] [106] [107] [108] [109] [110] [111]
17 CAVIN1 Caveolae-associated protein 1 [112] [113] [114] [115] [116] [117] [118]
18 GPAT3 Glycerol-3-phosphate acyltransferase 3 [119] [120] [121] [122] [123] [124] [125]
19 MIR6848 [126] [127] [128] [129] [130] [131] [132]
[1]
ref_hepatocyte AGPAT2
Mean 66.5
Standard deviation 62
Values 34 1.5e+02 1.2e+02 6.9 27
[2]
HepG2 AGPAT2
Mean 26
Standard deviation 11
Values 18 34
[3]
HepG2.C3A AGPAT2
Mean 29.8
Standard deviation 11
Values 22 37
[4]
HuH.7 AGPAT2
Mean 34
Standard deviation 6
Values 33 40 28
[5]
SNU475 AGPAT2
Mean 14.8
Standard deviation 0.28
Values 15 15
[6]
THLE AGPAT2
Mean 23.5
Standard deviation 5.8
Values 19 28
[7]
liver AGPAT2
Mean 82.3
Standard deviation 53
Values 53 26 1.5e+02 1e+02
[8]
ref_hepatocyte DGAT2
Mean 37.5
Standard deviation 34
Values 30 92 44 8 14
[9]
HepG2 DGAT2
Mean 52.1
Standard deviation 17
Values 64 40
[10]
HepG2.C3A DGAT2
Mean 25.5
Standard deviation 7.2
Values 31 20
[11]
HuH.7 DGAT2
Mean 13.1
Standard deviation 1.5
Values 12 15 12
[12]
SNU475 DGAT2
Mean 3
Standard deviation 1.1
Values 3.8 2.2
[13]
THLE DGAT2
Mean 8.53
Standard deviation 0.85
Values 7.9 9.1
[14]
liver DGAT2
Mean 74.5
Standard deviation 63
Values 65 23 1.6e+02 45
[15]
ref_hepatocyte HIF1A
Mean 26.5
Standard deviation 22
Values 30 5.8 8.1 27 61
[16]
HepG2 HIF1A
Mean 52.5
Standard deviation 22
Values 68 37
[17]
HepG2.C3A HIF1A
Mean 37.2
Standard deviation 10
Values 44 30
[18]
HuH.7 HIF1A
Mean 62
Standard deviation 17
Values 49 55 81
[19]
SNU475 HIF1A
Mean 237
Standard deviation 65
Values 1.9e+02 2.8e+02
[20]
THLE HIF1A
Mean 346
Standard deviation 60
Values 3.9e+02 3e+02
[21]
liver HIF1A
Mean 21.5
Standard deviation 8.5
Values 31 25 12 18
[22]
ref_hepatocyte CAV1
Mean 22.6
Standard deviation 36
Values 28 0.99 0.35 0 84
[23]
HepG2 CAV1
Mean 0.438
Standard deviation 0.44
Values 0.12 0.75
[24]
HepG2.C3A CAV1
Mean 0.055
Standard deviation 0.032
Values 0.032 0.078
[25]
HuH.7 CAV1
Mean 4.08
Standard deviation 1.9
Values 2.5 6.2 3.5
[26]
SNU475 CAV1
Mean 108
Standard deviation 15
Values 98 1.2e+02
[27]
THLE CAV1
Mean 47.4
Standard deviation 15
Values 37 58
[28]
liver CAV1
Mean 8.05
Standard deviation 2.9
Values 4.7 8.2 7.6 12
[29]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 20 17 14 27 26
[30]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1.1e+02 1e+02
[31]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[32]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 93 78 89
[33]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 57 55
[34]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[35]
liver GRB2
Mean 36.1
Standard deviation 16
Values 22 22 50 50
[36]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 11 14 13 7.2 8.4
[37]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 43 48
[38]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 43 55
[39]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 55 41 59
[40]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 31 39
[41]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[42]
liver AKT2
Mean 33
Standard deviation 9.4
Values 45 36 24 27
[43]
ref_hepatocyte BSCL2
Mean 10.4
Standard deviation 9.4
Values 7.9 20 21 1.1 2.4
[44]
HepG2 BSCL2
Mean 0.5
Standard deviation 0.015
Values 0.49 0.51
[45]
HepG2.C3A BSCL2
Mean 0.733
Standard deviation 0.19
Values 0.6 0.87
[46]
HuH.7 BSCL2
Mean 0.381
Standard deviation 0.13
Values 0.25 0.37 0.52
[47]
SNU475 BSCL2
Mean 0.594
Standard deviation 0.14
Values 0.5 0.69
[48]
THLE BSCL2
Mean 1.3
Standard deviation 0.27
Values 1.1 1.5
[49]
liver BSCL2
Mean 0.78
Standard deviation 0.59
Values 0.24 0.31 1.4 1.2
[50]
ref_hepatocyte LPIN2
Mean 9.55
Standard deviation 6.4
Values 6.4 20 10 4.3 6.3
[51]
HepG2 LPIN2
Mean 45.8
Standard deviation 12
Values 54 38
[52]
HepG2.C3A LPIN2
Mean 63.3
Standard deviation 20
Values 49 78
[53]
HuH.7 LPIN2
Mean 95
Standard deviation 11
Values 87 90 1.1e+02
[54]
SNU475 LPIN2
Mean 29.9
Standard deviation 6.8
Values 25 35
[55]
THLE LPIN2
Mean 23.9
Standard deviation 3
Values 22 26
[56]
liver LPIN2
Mean 84.1
Standard deviation 27
Values 1.2e+02 87 72 56
[57]
ref_hepatocyte LPIN1
Mean 6.88
Standard deviation 3.4
Values 12 5.9 7.4 3.3 5.5
[58]
HepG2 LPIN1
Mean 5.07
Standard deviation 1.3
Values 6 4.1
[59]
HepG2.C3A LPIN1
Mean 16
Standard deviation 7.5
Values 11 21
[60]
HuH.7 LPIN1
Mean 7.3
Standard deviation 3.1
Values 5.6 11 5.5
[61]
SNU475 LPIN1
Mean 18.1
Standard deviation 4.5
Values 15 21
[62]
THLE LPIN1
Mean 10.6
Standard deviation 1.8
Values 9.3 12
[63]
liver LPIN1
Mean 26.6
Standard deviation 4.2
Values 23 31 23 30
[64]
ref_hepatocyte DGAT1
Mean 6.41
Standard deviation 5.1
Values 0.65 9.5 10 11 1.1
[65]
HepG2 DGAT1
Mean 35.1
Standard deviation 15
Values 46 25
[66]
HepG2.C3A DGAT1
Mean 27.7
Standard deviation 5.1
Values 24 31
[67]
HuH.7 DGAT1
Mean 37.4
Standard deviation 7
Values 43 30 39
[68]
SNU475 DGAT1
Mean 9.37
Standard deviation 0.38
Values 9.6 9.1
[69]
THLE DGAT1
Mean 9.47
Standard deviation 1.3
Values 10 8.5
[70]
liver DGAT1
Mean 10.5
Standard deviation 4.6
Values 6.4 6.7 16 13
[71]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 2.7 4.7 2.1 4.3 1.5
[72]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 23 35
[73]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 13 22
[74]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 37 48 49
[75]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 22 15
[76]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[77]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 22 18 23 12
[78]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 0.23 5.5 2.6 2.2 0.039
[79]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 8.4 9.4
[80]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.021 0.019
[81]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.5 4.8 8.9
[82]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 8.9 12
[83]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[84]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 5 4.4 8.9 5.1
[85]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 0.94 1.2 2.3 2.6
[86]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 4.3 2.1
[87]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 9.6 8
[88]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 7 12 10
[89]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 6.8 8.1
[90]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[91]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 13 15 6.1 6
[92]
ref_hepatocyte LPIN3
Mean 1.56
Standard deviation 0.32
Values 1.7 1.5 1.8 1.8 1
[93]
HepG2 LPIN3
Mean 10.2
Standard deviation 0.35
Values 10 10
[94]
HepG2.C3A LPIN3
Mean 18.5
Standard deviation 4.3
Values 15 22
[95]
HuH.7 LPIN3
Mean 4.79
Standard deviation 1.8
Values 4.6 6.7 3.1
[96]
SNU475 LPIN3
Mean 7.59
Standard deviation 4.2
Values 4.6 11
[97]
THLE LPIN3
Mean 6.41
Standard deviation 1.1
Values 7.2 5.6
[98]
liver LPIN3
Mean 28.1
Standard deviation 23
Values 11 9.4 58 34
[99]
ref_hepatocyte ITGB4
Mean 0.1
Standard deviation 0.079
Values 0 0.11 0.17 0.18 0.039
[100]
HepG2 ITGB4
Mean 11.6
Standard deviation 4.7
Values 8.3 15
[101]
HepG2.C3A ITGB4
Mean 10.9
Standard deviation 2.2
Values 9.3 12
[102]
HuH.7 ITGB4
Mean 0.893
Standard deviation 0.17
Values 0.69 0.98 1
[103]
SNU475 ITGB4
Mean 3.3
Standard deviation 2.3
Values 1.7 4.9
[104]
THLE ITGB4
Mean 0.838
Standard deviation 0.17
Values 0.96 0.72
[105]
liver ITGB4
Mean 0.998
Standard deviation 0.38
Values 1.4 0.96 1.1 0.51
[106]
ref_hepatocyte INS
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[107]
HepG2 INS
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[108]
HepG2.C3A INS
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 INS
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 INS
Mean 0
Standard deviation 0
Values 0 0
[111]
THLE INS
Mean 0
Standard deviation 0
Values 0 0
[112]
liver INS
Mean 0.0838
Standard deviation 0.13
Values 0.28 0.057 0 0
[113]
ref_hepatocyte CAVIN1
Missing
[114]
HepG2 CAVIN1
Missing
[115]
HepG2.C3A CAVIN1
Missing
[116]
HuH.7 CAVIN1
Missing
[117]
SNU475 CAVIN1
Missing
[118]
THLE CAVIN1
Missing
[119]
liver CAVIN1
Missing
[120]
ref_hepatocyte GPAT3
Missing
[121]
HepG2 GPAT3
Missing
[122]
HepG2.C3A GPAT3
Missing
[123]
HuH.7 GPAT3
Missing
[124]
SNU475 GPAT3
Missing
[125]
THLE GPAT3
Missing
[126]
liver GPAT3
Missing
[127]
ref_hepatocyte MIR6848
Missing
[128]
HepG2 MIR6848
Missing
[129]
HepG2.C3A MIR6848
Missing
[130]
HuH.7 MIR6848
Missing
[131]
SNU475 MIR6848
Missing
[132]
THLE MIR6848
Missing
[133]
liver MIR6848
Missing