WP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isofor | 0.23[1] | -0.55[2] | -0.76[3] | 0.05[4] | -0.79[5] | -0.67[6] | |
2 | PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | -0.29[7] | -0.80[8] | -1.58[9] | -0.42[10] | -0.47[11] | -0.92[12] | |
3 | PPP2CB | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | -0.96[13] | -1.90[14] | -1.97[15] | -1.62[16] | -1.88[17] | -1.80[18] | |
4 | RAD21 | Double-strand-break repair protein rad21 homolog | [19] | -0.13[20] | 0.66[21] | 0.61[22] | 0.90[23] | 0.36[24] | -0.44[25] |
5 | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | -1.69[26] | -1.40[27] | -0.82[28] | -1.41[29] | -2.70[30] | -0.18[31] | |
6 | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isofor | -0.87[32] | -0.60[33] | -1.04[34] | -0.22[35] | -0.57[36] | -1.01[37] | |
7 | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform | -0.12[38] | -1.24[39] | -0.97[40] | -0.89[41] | -1.27[42] | 2.12[43] | |
8 | SMC3 | Structural maintenance of chromosomes protein 3 | [44] | -1.74[45] | 0.31[46] | 0.64[47] | -0.75[48] | -0.48[49] | -0.76[50] |
9 | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform | 0.68[51] | -0.16[52] | -0.74[53] | 0.13[54] | -0.15[55] | -1.08[56] | |
10 | PDS5A | Sister chromatid cohesion protein PDS5 homolog A | [57] | 0.31[58] | 0.57[59] | 0.61[60] | 0.29[61] | 0.82[62] | 1.38[63] |
11 | HDAC8 | Histone deacetylase 8 | [64] | -1.54[65] | -2.35[66] | -2.21[67] | -1.93[68] | -1.86[69] | -1.17[70] |
12 | CDK1 | Cyclin-dependent kinase 1 | [71] | 0.69[72] | 2.14[73] | 0.74[74] | 1.11[75] | 1.77[76] | -3.28[77] |
13 | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isofor | -0.45[78] | -0.88[79] | -1.49[80] | -0.30[81] | -0.67[82] | -0.62[83] | |
14 | AURKB | Aurora kinase B | [84] | 0.02[85] | -0.22[86] | 0.66[87] | -0.82[88] | -0.44[89] | -4.17[90] |
15 | STAG2 | Cohesin subunit SA-2 | [91] | -0.28[92] | 1.12[93] | 2.00[94] | 1.37[95] | 0.70[96] | 1.14[97] |
16 | PLK1 | Serine/threonine-protein kinase PLK1 | [98] | 1.92[99] | 1.06[100] | 0.78[101] | 0.08[102] | 0.96[103] | -3.45[104] |
17 | SMC1A | Structural maintenance of chromosomes protein 1A | [105] | 1.53[106] | 0.80[107] | 1.66[108] | 1.85[109] | 2.54[110] | 1.63[111] |
18 | ESCO1 | N-acetyltransferase ESCO1 | [112] | -1.66[113] | 0.04[114] | -0.01[115] | -0.94[116] | -1.59[117] | -0.19[118] |
19 | CDCA5 | Sororin | [119] | 1.10[120] | 0.47[121] | -0.01[122] | 0.09[123] | 0.56[124] | -3.76[125] |
20 | PTTG1 | Securin | [126] | 0.93[127] | 0.99[128] | 1.45[129] | 0.26[130] | 1.39[131] | -2.89[132] |
21 | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform | 0.21[133] | -0.63[134] | -1.42[135] | -0.87[136] | 0.13[137] | -0.72[138] | |
22 | NIPBL | Nipped-B-like protein | [139] | 0.35[140] | 1.78[141] | 2.20[142] | 1.54[143] | 1.50[144] | 2.69[145] |
23 | MAU2 | MAU2 chromatid cohesion factor homolog | [146] | 1.54[147] | 1.15[148] | 2.23[149] | 0.13[150] | 1.06[151] | 1.29[152] |
24 | PDS5B | Sister chromatid cohesion protein PDS5 homolog B | [153] | 0.55[154] | 1.21[155] | 1.36[156] | 0.97[157] | 0.80[158] | 1.76[159] |
25 | ESCO2 | N-acetyltransferase ESCO2 | [160] | 0.26[161] | 0.92[162] | 0.19[163] | 0.37[164] | 0.45[165] | -2.21[166] |
26 | STAG3 | Cohesin subunit SA-3 | [167] | -3.18[168] | -3.46[169] | -4.47[170] | -3.98[171] | -4.71[172] | -0.82[173] |
27 | APC | Adenomatous polyposis coli protein | [174] | 0.00[175] | 1.07[176] | 0.77[177] | 1.06[178] | 1.54[179] | 2.92[180] |
28 | ESPL1 | Separin | [181] | 3.36[182] | 3.11[183] | 2.93[184] | 3.33[185] | 3.20[186] | 1.36[187] |
29 | REC8 | Meiotic recombination protein REC8 homolog | [188] | -0.01[189] | -0.18[190] | -0.12[191] | -0.40[192] | 3.87[193] | 0.66[194] |
30 | SGO2 | Shugoshin 2 | [195] | [196] | [197] | [198] | [199] | [200] | [201] |
31 | PTPA | Serine/threonine-protein phosphatase 2A activator | [202] | [203] | [204] | [205] | [206] | [207] | [208] |
32 | WAPL | Wings apart-like protein homolog | [209] | [210] | [211] | [212] | [213] | [214] | [215] |
33 | SGO1 | Shugoshin 1 | [216] | [217] | [218] | [219] | [220] | [221] | [222] |
34 | MIR3610 | [223] | [224] | [225] | [226] | [227] | [228] | [229] | |
35 | SMC1B | Structural maintenance of chromosomes protein 1B | [230] | [231] | [232] | [233] | [234] | [235] | [236] |