WP_CHOLESTEROL_METABOLISM_WITH_BLOCH_AND_KANDUTSCHRUSSELL_PATHWAYS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HMGCS2 Hydroxymethylglutaryl-CoA synthase, mitochondrial [1] -12.00[2] -11.14[3] -4.60[4] -8.41[5] -12.80[6] 0.14[7]
2 SCD Acyl-CoA desaturase [8] 0.80[9] 1.15[10] 1.55[11] -0.80[12] -1.70[13] -0.19[14]
3 EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase [15] -2.88[16] -2.36[17] -1.93[18] -2.57[19] -1.84[20] -2.08[21]
4 ACSL1 Long-chain-fatty-acid--CoA ligase 1 [22] -0.60[23] -4.54[24] -4.30[25] -2.78[26] 0.41[27] 1.57[28]
5 FDPS Farnesyl pyrophosphate synthase [29] -1.54[30] -1.39[31] -1.48[32] -0.77[33] -0.86[34] -2.29[35]
6 DHCR24 Delta(24)-sterol reductase [36] 0.87[37] 0.28[38] 0.24[39] -0.42[40] 0.38[41] 0.85[42]
7 CYP27A1 Sterol 26-hydroxylase, mitochondrial [43] -0.65[44] -1.34[45] -4.81[46] -2.38[47] -3.91[48] -0.60[49]
8 HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic [50] -2.38[51] -0.62[52] 0.39[53] -2.11[54] -2.33[55] -0.93[56]
9 MSMO1 Methylsterol monooxygenase 1 [57] -2.14[58] -0.61[59] -0.63[60] -2.05[61] -1.22[62] -0.17[63]
10 FDFT1 Squalene synthase [64] -0.33[65] 0.14[66] -0.68[67] -1.59[68] -0.51[69] -1.64[70]
11 ACAT2 Acetyl-CoA acetyltransferase, cytosolic [71] -0.72[72] -0.17[73] -1.04[74] -1.43[75] -0.88[76] -1.42[77]
12 CYP51A1 Lanosterol 14-alpha demethylase [78] -1.28[79] -0.36[80] -0.81[81] -0.25[82] -0.57[83] 0.12[84]
13 ELOVL5 Elongation of very long chain fatty acids protein 5 [85] 0.09[86] -1.26[87] -0.82[88] 1.90[89] 1.36[90] -1.67[91]
14 IDI1 Isopentenyl-diphosphate Delta-isomerase 1 [92] -1.42[93] 0.59[94] -1.21[95] 0.61[96] -0.58[97] -0.37[98]
15 ACOT2 Acyl-coenzyme A thioesterase 2, mitochondrial [99] -1.19[100] -1.62[101] -4.65[102] -2.00[103] -1.69[104] -1.17[105]
16 SQLE Squalene monooxygenase [106] -0.44[107] 0.67[108] 0.02[109] 0.03[110] -0.53[111] -1.00[112]
17 DHCR7 7-dehydrocholesterol reductase [113] 0.42[114] 0.67[115] 0.54[116] -0.46[117] -0.20[118] 0.43[119]
18 SREBF1 Sterol regulatory element-binding protein 1 [120] 0.66[121] -0.54[122] -0.37[123] 0.64[124] 0.84[125] -0.20[126]
19 TM7SF2 Delta(14)-sterol reductase [127] 0.02[128] -0.54[129] -1.27[130] -0.37[131] -2.15[132] -0.65[133]
20 PMVK Phosphomevalonate kinase [134] -1.11[135] -2.51[136] -1.67[137] 0.13[138] -0.10[139] -2.86[140]
21 FADS2 Fatty acid desaturase 2 [141] -0.08[142] -0.10[143] 1.77[144] 2.50[145] 0.04[146] -1.09[147]
22 MVD Diphosphomevalonate decarboxylase [148] 0.18[149] 1.18[150] -0.01[151] -0.22[152] -0.18[153] -1.13[154]
23 NSDHL Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating [155] -0.39[156] -0.90[157] -1.88[158] 0.40[159] -0.14[160] -1.35[161]
24 ACSL3 Long-chain-fatty-acid--CoA ligase 3 [162] 1.53[163] 2.19[164] 0.99[165] 2.39[166] 1.91[167] 0.03[168]
25 FADS1 Fatty acid desaturase 1 [169] 1.80[170] 1.42[171] 2.38[172] 2.69[173] 2.46[174] 0.46[175]
26 FASN Fatty acid synthase [176] 3.83[177] 2.99[178] 3.17[179] 2.91[180] 2.97[181] 1.82[182]
27 LSS Lanosterol synthase [183] 0.79[184] 1.41[185] -0.02[186] 1.29[187] 0.90[188] 0.37[189]
28 HSD17B7 3-keto-steroid reductase [190] -1.79[191] -1.42[192] -1.77[193] -1.21[194] -1.55[195] -1.47[196]
29 HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase [197] 0.87[198] 2.15[199] 2.03[200] 1.87[201] 1.58[202] 0.68[203]
30 NR1H3 Oxysterols receptor LXR-alpha [204] -0.24[205] -0.69[206] -0.15[207] -0.56[208] -1.88[209] -1.00[210]
31 MVK Mevalonate kinase [211] -0.88[212] 0.00[213] -0.93[214] -1.04[215] -1.23[216] -0.45[217]
32 NR1H2 Oxysterols receptor LXR-beta [218] 0.75[219] -0.85[220] -0.87[221] 1.93[222] 2.31[223] -0.67[224]
33 ELOVL2 Elongation of very long chain fatty acids protein 2 [225] 1.42[226] 1.76[227] 0.08[228] 0.31[229] -1.71[230] -0.51[231]
34 LBR Lamin-B receptor [232] 2.17[233] 1.40[234] 1.87[235] 3.51[236] 2.58[237] 0.09[238]
35 SREBF2 Sterol regulatory element-binding protein 2 [239] 2.69[240] 2.06[241] 2.87[242] 1.84[243] 2.15[244] 0.79[245]
36 ACSL4 Long-chain-fatty-acid--CoA ligase 4 [246] 4.15[247] 4.40[248] 4.31[249] 3.72[250] 4.58[251] 0.27[252]
37 ABCA1 ATP-binding cassette sub-family A member 1 [253] 3.10[254] 2.53[255] 1.92[256] 3.39[257] 3.98[258] 4.53[259]
38 SOAT1 Sterol O-acyltransferase 1 [260] 2.45[261] 1.52[262] 1.91[263] 5.08[264] 4.72[265] 0.97[266]
39 GGPS1 Geranylgeranyl pyrophosphate synthase [267] 1.64[268] 1.42[269] 1.00[270] 3.78[271] 2.17[272] -0.34[273]
40 SOAT2 Sterol O-acyltransferase 2 [274] 2.76[275] 3.76[276] 2.04[277] -4.11[278] -4.64[279] -2.03[280]
41 ABCG1 ATP-binding cassette sub-family G member 1 [281] 0.42[282] -7.01[283] -1.71[284] -3.31[285] 1.81[286] 1.23[287]
42 MYLIP E3 ubiquitin-protein ligase MYLIP [288] 3.42[289] 1.69[290] 2.23[291] 4.22[292] 3.80[293] 1.34[294]
43 ELOVL4 Elongation of very long chain fatty acids protein 4 [295] 0.21[296] [297] -2.78[298] 3.37[299] 6.34[300] -1.53[301]
44 CYP46A1 Cholesterol 24-hydroxylase [302] -2.36[303] -2.50[304] -3.90[305] -0.38[306] 0.84[307] 1.56[308]
45 ELOVL3 Elongation of very long chain fatty acids protein 3 [309] 4.57[310] 2.49[311] 2.32[312] 2.25[313] 6.24[314] [315]
46 CH25H Cholesterol 25-hydroxylase [316] -1.70[317] [318] -3.21[319] 10.40[320] 3.91[321] 2.41[322]
47 MIR1908 [323] [324] [325] [326] [327] [328] [329]
48 SC5D Lathosterol oxidase [330] [331] [332] [333] [334] [335] [336]
[1]
ref_hepatocyte HMGCS2
Mean 222
Standard deviation 3.3e+02
Values 3.3 7.2e+02 3.8e+02 1.4 0.38
[2]
HepG2 HMGCS2
Mean 0.0443
Standard deviation 0.046
Values 0.077 0.011
[3]
HepG2.C3A HMGCS2
Mean 0.2
Standard deviation 0.1
Values 0.13 0.27
[4]
HuH.7 HMGCS2
Mean 23.3
Standard deviation 9.9
Values 17 35 18
[5]
SNU475 HMGCS2
Mean 0.265
Standard deviation 0.27
Values 0.071 0.46
[6]
THLE HMGCS2
Mean 0.0139
Standard deviation 0.0029
Values 0.012 0.016
[7]
liver HMGCS2
Mean 562
Standard deviation 3.1e+02
Values 3.5e+02 2.7e+02 9.5e+02 6.9e+02
[8]
ref_hepatocyte SCD
Mean 184
Standard deviation 1.7e+02
Values 35 3.1e+02 1.3e+02 4.1e+02 33
[9]
HepG2 SCD
Mean 263
Standard deviation 44
Values 2.9e+02 2.3e+02
[10]
HepG2.C3A SCD
Mean 832
Standard deviation 2.9e+02
Values 6.3e+02 1e+03
[11]
HuH.7 SCD
Mean 1.37e+03
Standard deviation 3.6e+02
Values 1e+03 1.7e+03 1.4e+03
[12]
SNU475 SCD
Mean 42.8
Standard deviation 2.4
Values 41 45
[13]
THLE SCD
Mean 25.4
Standard deviation 2.3
Values 24 27
[14]
liver SCD
Mean 369
Standard deviation 2.8e+02
Values 1.4e+02 5.6e+02 1.1e+02 6.7e+02
[15]
ref_hepatocyte EBP
Mean 181
Standard deviation 65
Values 1e+02 1.9e+02 1.5e+02 1.8e+02 2.8e+02
[16]
HepG2 EBP
Mean 20.1
Standard deviation 4.7
Values 23 17
[17]
HepG2.C3A EBP
Mean 71.4
Standard deviation 13
Values 63 80
[18]
HuH.7 EBP
Mean 120
Standard deviation 17
Values 1.4e+02 1.1e+02 1.1e+02
[19]
SNU475 EBP
Mean 12.4
Standard deviation 1.5
Values 13 11
[20]
THLE EBP
Mean 22.6
Standard deviation 3.6
Values 20 25
[21]
liver EBP
Mean 97.6
Standard deviation 78
Values 37 24 1.8e+02 1.5e+02
[22]
ref_hepatocyte ACSL1
Mean 173
Standard deviation 2.2e+02
Values 13 5e+02 3.2e+02 17 17
[23]
HepG2 ACSL1
Mean 93.9
Standard deviation 14
Values 84 1e+02
[24]
HepG2.C3A ACSL1
Mean 15.2
Standard deviation 4.9
Values 12 19
[25]
HuH.7 ACSL1
Mean 22.4
Standard deviation 13
Values 14 38 15
[26]
SNU475 ACSL1
Mean 10.3
Standard deviation 0.5
Values 11 9.9
[27]
THLE ACSL1
Mean 103
Standard deviation 35
Values 1.3e+02 78
[28]
liver ACSL1
Mean 1.18e+03
Standard deviation 2.6e+02
Values 1.6e+03 1.1e+03 9.5e+02 1.1e+03
[29]
ref_hepatocyte FDPS
Mean 168
Standard deviation 1.2e+02
Values 65 1.3e+02 1e+02 1.8e+02 3.6e+02
[30]
HepG2 FDPS
Mean 47.3
Standard deviation 9.8
Values 54 40
[31]
HepG2.C3A FDPS
Mean 130
Standard deviation 36
Values 1e+02 1.5e+02
[32]
HuH.7 FDPS
Mean 153
Standard deviation 26
Values 1.8e+02 1.3e+02 1.4e+02
[33]
SNU475 FDPS
Mean 40
Standard deviation 13
Values 31 49
[34]
THLE FDPS
Mean 41.3
Standard deviation 7.5
Values 36 47
[35]
liver FDPS
Mean 78.7
Standard deviation 39
Values 50 54 76 1.3e+02
[36]
ref_hepatocyte DHCR24
Mean 160
Standard deviation 83
Values 44 2.6e+02 2e+02 1.8e+02 1.1e+02
[37]
HepG2 DHCR24
Mean 239
Standard deviation 90
Values 3e+02 1.8e+02
[38]
HepG2.C3A DHCR24
Mean 395
Standard deviation 1.3e+02
Values 3e+02 4.9e+02
[39]
HuH.7 DHCR24
Mean 482
Standard deviation 1.1e+02
Values 3.7e+02 5.9e+02 4.9e+02
[40]
SNU475 DHCR24
Mean 48.6
Standard deviation 27
Values 29 68
[41]
THLE DHCR24
Mean 93.2
Standard deviation 28
Values 73 1.1e+02
[42]
liver DHCR24
Mean 661
Standard deviation 1.8e+02
Values 5.3e+02 6.7e+02 5.4e+02 9.1e+02
[43]
ref_hepatocyte CYP27A1
Mean 135
Standard deviation 1.6e+02
Values 18 3.7e+02 2.1e+02 62 8
[44]
HepG2 CYP27A1
Mean 70.5
Standard deviation 16
Values 82 59
[45]
HepG2.C3A CYP27A1
Mean 108
Standard deviation 25
Values 90 1.3e+02
[46]
HuH.7 CYP27A1
Mean 12.2
Standard deviation 7.3
Values 8.9 21 7.2
[47]
SNU475 CYP27A1
Mean 10.5
Standard deviation 1.6
Values 9.4 12
[48]
THLE CYP27A1
Mean 4.01
Standard deviation 0.91
Values 4.7 3.4
[49]
liver CYP27A1
Mean 204
Standard deviation 1e+02
Values 1.1e+02 1.2e+02 3.3e+02 2.5e+02
[50]
ref_hepatocyte HMGCS1
Mean 128
Standard deviation 1e+02
Values 58 72 32 2.5e+02 2.3e+02
[51]
HepG2 HMGCS1
Mean 20.3
Standard deviation 12
Values 28 12
[52]
HepG2.C3A HMGCS1
Mean 170
Standard deviation 81
Values 1.1e+02 2.3e+02
[53]
HuH.7 HMGCS1
Mean 427
Standard deviation 1.7e+02
Values 3.3e+02 6.2e+02 3.3e+02
[54]
SNU475 HMGCS1
Mean 12.1
Standard deviation 4.1
Values 9.2 15
[55]
THLE HMGCS1
Mean 11.4
Standard deviation 0.78
Values 11 12
[56]
liver HMGCS1
Mean 154
Standard deviation 63
Values 2.2e+02 1.9e+02 79 1.3e+02
[57]
ref_hepatocyte MSMO1
Mean 108
Standard deviation 90
Values 21 2.6e+02 1e+02 88 72
[58]
HepG2 MSMO1
Mean 20.1
Standard deviation 11
Values 28 12
[59]
HepG2.C3A MSMO1
Mean 144
Standard deviation 56
Values 1e+02 1.8e+02
[60]
HuH.7 MSMO1
Mean 177
Standard deviation 63
Values 1.6e+02 2.5e+02 1.3e+02
[61]
SNU475 MSMO1
Mean 10.6
Standard deviation 4
Values 7.8 13
[62]
THLE MSMO1
Mean 20.7
Standard deviation 3.4
Values 18 23
[63]
liver MSMO1
Mean 219
Standard deviation 94
Values 1.7e+02 1.9e+02 1.6e+02 3.6e+02
[64]
ref_hepatocyte FDFT1
Mean 87.4
Standard deviation 77
Values 41 38 48 2.2e+02 91
[65]
HepG2 FDFT1
Mean 56.9
Standard deviation 24
Values 74 40
[66]
HepG2.C3A FDFT1
Mean 196
Standard deviation 63
Values 1.5e+02 2.4e+02
[67]
HuH.7 FDFT1
Mean 138
Standard deviation 16
Values 1.6e+02 1.3e+02 1.3e+02
[68]
SNU475 FDFT1
Mean 11.8
Standard deviation 4
Values 9 15
[69]
THLE FDFT1
Mean 27.4
Standard deviation 0.93
Values 27 28
[70]
liver FDFT1
Mean 64.1
Standard deviation 23
Values 52 45 62 98
[71]
ref_hepatocyte ACAT2
Mean 68.2
Standard deviation 50
Values 17 76 49 1.5e+02 51
[72]
HepG2 ACAT2
Mean 33.9
Standard deviation 23
Values 50 18
[73]
HepG2.C3A ACAT2
Mean 123
Standard deviation 6.4
Values 1.2e+02 1.3e+02
[74]
HuH.7 ACAT2
Mean 84.1
Standard deviation 10
Values 95 76 82
[75]
SNU475 ACAT2
Mean 10.3
Standard deviation 0.34
Values 10 11
[76]
THLE ACAT2
Mean 16.6
Standard deviation 3.1
Values 14 19
[77]
liver ACAT2
Mean 58.5
Standard deviation 28
Values 39 47 48 1e+02
[78]
ref_hepatocyte CYP51A1
Mean 63
Standard deviation 38
Values 38 46 27 1.2e+02 88
[79]
HepG2 CYP51A1
Mean 21.2
Standard deviation 5.5
Values 25 17
[80]
HepG2.C3A CYP51A1
Mean 99.9
Standard deviation 49
Values 66 1.3e+02
[81]
HuH.7 CYP51A1
Mean 91.5
Standard deviation 23
Values 78 1.2e+02 79
[82]
SNU475 CYP51A1
Mean 21.5
Standard deviation 2.5
Values 20 23
[83]
THLE CYP51A1
Mean 19
Standard deviation 1.2
Values 18 20
[84]
liver CYP51A1
Mean 156
Standard deviation 52
Values 1.5e+02 1.8e+02 89 2.1e+02
[85]
ref_hepatocyte ELOVL5
Mean 56.8
Standard deviation 44
Values 33 24 23 1.2e+02 80
[86]
HepG2 ELOVL5
Mean 49.5
Standard deviation 3.3
Values 47 52
[87]
HepG2.C3A ELOVL5
Mean 48.2
Standard deviation 12
Values 40 56
[88]
HuH.7 ELOVL5
Mean 81.7
Standard deviation 21
Values 61 1e+02 81
[89]
SNU475 ELOVL5
Mean 86.1
Standard deviation 20
Values 72 1e+02
[90]
THLE ELOVL5
Mean 65.5
Standard deviation 8
Values 60 71
[91]
liver ELOVL5
Mean 40.8
Standard deviation 18
Values 30 37 29 68
[92]
ref_hepatocyte IDI1
Mean 49.3
Standard deviation 26
Values 14 62 33 79 59
[93]
HepG2 IDI1
Mean 15.1
Standard deviation 12
Values 23 6.9
[94]
HepG2.C3A IDI1
Mean 151
Standard deviation 3.5
Values 1.5e+02 1.5e+02
[95]
HuH.7 IDI1
Mean 54.3
Standard deviation 7.2
Values 59 58 46
[96]
SNU475 IDI1
Mean 30.7
Standard deviation 8.7
Values 24 37
[97]
THLE IDI1
Mean 14.8
Standard deviation 3.6
Values 12 17
[98]
liver IDI1
Mean 87.2
Standard deviation 46
Values 55 57 84 1.5e+02
[99]
ref_hepatocyte ACOT2
Mean 36.1
Standard deviation 30
Values 13 48 80 34 5.9
[100]
HepG2 ACOT2
Mean 13
Standard deviation 0.42
Values 13 13
[101]
HepG2.C3A ACOT2
Mean 23.9
Standard deviation 6.7
Values 19 29
[102]
HuH.7 ACOT2
Mean 3.66
Standard deviation 0.25
Values 3.9 3.7 3.4
[103]
SNU475 ACOT2
Mean 3.66
Standard deviation 0.54
Values 3.3 4
[104]
THLE ACOT2
Mean 5.01
Standard deviation 1.6
Values 3.9 6.1
[105]
liver ACOT2
Mean 36.7
Standard deviation 14
Values 35 22 55 35
[106]
ref_hepatocyte SQLE
Mean 34.4
Standard deviation 33
Values 17 9.9 12 86 47
[107]
HepG2 SQLE
Mean 20.7
Standard deviation 9.1
Values 27 14
[108]
HepG2.C3A SQLE
Mean 111
Standard deviation 44
Values 80 1.4e+02
[109]
HuH.7 SQLE
Mean 88.5
Standard deviation 14
Values 75 1e+02 88
[110]
SNU475 SQLE
Mean 14.3
Standard deviation 3.6
Values 12 17
[111]
THLE SQLE
Mean 10.7
Standard deviation 4.6
Values 7.4 14
[112]
liver SQLE
Mean 39.4
Standard deviation 14
Values 49 28 27 54
[113]
ref_hepatocyte DHCR7
Mean 31.8
Standard deviation 19
Values 23 59 43 21 13
[114]
HepG2 DHCR7
Mean 34.7
Standard deviation 11
Values 43 27
[115]
HepG2.C3A DHCR7
Mean 103
Standard deviation 68
Values 54 1.5e+02
[116]
HuH.7 DHCR7
Mean 117
Standard deviation 29
Values 90 1.5e+02 1.1e+02
[117]
SNU475 DHCR7
Mean 9.4
Standard deviation 1.9
Values 8 11
[118]
THLE DHCR7
Mean 12.4
Standard deviation 3.1
Values 10 15
[119]
liver DHCR7
Mean 98.2
Standard deviation 72
Values 68 50 69 2.1e+02
[120]
ref_hepatocyte SREBF1
Mean 27.4
Standard deviation 36
Values 6.5 85 42 1.8 1.2
[121]
HepG2 SREBF1
Mean 35.4
Standard deviation 8.8
Values 29 42
[122]
HepG2.C3A SREBF1
Mean 38.3
Standard deviation 21
Values 24 53
[123]
HuH.7 SREBF1
Mean 53.8
Standard deviation 3.4
Values 56 55 50
[124]
SNU475 SREBF1
Mean 17.3
Standard deviation 4.1
Values 14 20
[125]
THLE SREBF1
Mean 21.9
Standard deviation 0.74
Values 21 22
[126]
liver SREBF1
Mean 54.7
Standard deviation 14
Values 35 59 58 67
[127]
ref_hepatocyte TM7SF2
Mean 22.9
Standard deviation 25
Values 0.92 62 26 24 1.4
[128]
HepG2 TM7SF2
Mean 19
Standard deviation 5.7
Values 23 15
[129]
HepG2.C3A TM7SF2
Mean 32
Standard deviation 9.1
Values 26 38
[130]
HuH.7 TM7SF2
Mean 24.2
Standard deviation 0.33
Values 24 24 25
[131]
SNU475 TM7SF2
Mean 7.18
Standard deviation 2.2
Values 5.6 8.8
[132]
THLE TM7SF2
Mean 2.32
Standard deviation 0.45
Values 2.6 2
[133]
liver TM7SF2
Mean 33.4
Standard deviation 23
Values 16 24 27 67
[134]
ref_hepatocyte PMVK
Mean 22.4
Standard deviation 12
Values 20 34 33 3.4 22
[135]
HepG2 PMVK
Mean 8.49
Standard deviation 1
Values 7.8 9.2
[136]
HepG2.C3A PMVK
Mean 7.97
Standard deviation 0.74
Values 7.4 8.5
[137]
HuH.7 PMVK
Mean 17.9
Standard deviation 3.9
Values 22 14 18
[138]
SNU475 PMVK
Mean 9.92
Standard deviation 2.1
Values 8.5 11
[139]
THLE PMVK
Mean 9.34
Standard deviation 1.8
Values 8 11
[140]
liver PMVK
Mean 7.06
Standard deviation 5.2
Values 3.4 2.4 13 9
[141]
ref_hepatocyte FADS2
Mean 21
Standard deviation 10
Values 24 36 21 8.2 16
[142]
HepG2 FADS2
Mean 16.3
Standard deviation 4.9
Values 20 13
[143]
HepG2.C3A FADS2
Mean 39.8
Standard deviation 12
Values 31 49
[144]
HuH.7 FADS2
Mean 181
Standard deviation 24
Values 1.6e+02 1.7e+02 2.1e+02
[145]
SNU475 FADS2
Mean 48.4
Standard deviation 26
Values 30 67
[146]
THLE FADS2
Mean 9.67
Standard deviation 2.5
Values 7.9 11
[147]
liver FADS2
Mean 22.5
Standard deviation 17
Values 31 41 3.1 15
[148]
ref_hepatocyte MVD
Mean 20.1
Standard deviation 9.1
Values 15 24 17 34 10
[149]
HepG2 MVD
Mean 18.7
Standard deviation 5.5
Values 23 15
[150]
HepG2.C3A MVD
Mean 92.8
Standard deviation 59
Values 51 1.3e+02
[151]
HuH.7 MVD
Mean 50.8
Standard deviation 5.1
Values 56 45 51
[152]
SNU475 MVD
Mean 7
Standard deviation 2.5
Values 5.2 8.8
[153]
THLE MVD
Mean 7.96
Standard deviation 0.012
Values 8 8
[154]
liver MVD
Mean 21.1
Standard deviation 12
Values 19 14 12 39
[155]
ref_hepatocyte NSDHL
Mean 19.7
Standard deviation 8
Values 12 24 31 14 17
[156]
HepG2 NSDHL
Mean 12.3
Standard deviation 4.3
Values 15 9.2
[157]
HepG2.C3A NSDHL
Mean 21.5
Standard deviation 0.63
Values 21 22
[158]
HuH.7 NSDHL
Mean 13.6
Standard deviation 1.6
Values 15 12 14
[159]
SNU475 NSDHL
Mean 10.5
Standard deviation 1
Values 9.8 11
[160]
THLE NSDHL
Mean 8.01
Standard deviation 1.5
Values 6.9 9.1
[161]
liver NSDHL
Mean 17.7
Standard deviation 6.5
Values 15 11 18 26
[162]
ref_hepatocyte ACSL3
Mean 17.7
Standard deviation 9.8
Values 21 12 10 33 11
[163]
HepG2 ACSL3
Mean 41.8
Standard deviation 11
Values 49 34
[164]
HepG2.C3A ACSL3
Mean 164
Standard deviation 67
Values 1.2e+02 2.1e+02
[165]
HuH.7 ACSL3
Mean 89.4
Standard deviation 16
Values 74 1.1e+02 89
[166]
SNU475 ACSL3
Mean 37.6
Standard deviation 1.8
Values 39 36
[167]
THLE ACSL3
Mean 29.6
Standard deviation 1.5
Values 29 31
[168]
liver ACSL3
Mean 41.4
Standard deviation 11
Values 37 50 28 50
[169]
ref_hepatocyte FADS1
Mean 17.1
Standard deviation 5.7
Values 22 10 11 21 20
[170]
HepG2 FADS1
Mean 48.8
Standard deviation 2.8
Values 47 51
[171]
HepG2.C3A FADS1
Mean 92.7
Standard deviation 11
Values 85 1e+02
[172]
HuH.7 FADS1
Mean 225
Standard deviation 35
Values 1.9e+02 2.5e+02 2.4e+02
[173]
SNU475 FADS1
Mean 44.8
Standard deviation 3.1
Values 43 47
[174]
THLE FADS1
Mean 42.2
Standard deviation 8
Values 37 48
[175]
liver FADS1
Mean 53.9
Standard deviation 20
Values 53 60 27 75
[176]
ref_hepatocyte FASN
Mean 16.9
Standard deviation 11
Values 11 22 17 31 3.5
[177]
HepG2 FASN
Mean 197
Standard deviation 11
Values 2e+02 1.9e+02
[178]
HepG2.C3A FASN
Mean 273
Standard deviation 1.4e+02
Values 1.7e+02 3.7e+02
[179]
HuH.7 FASN
Mean 387
Standard deviation 1.1e+02
Values 2.9e+02 3.8e+02 5e+02
[180]
SNU475 FASN
Mean 51.5
Standard deviation 12
Values 43 60
[181]
THLE FASN
Mean 59
Standard deviation 19
Values 46 72
[182]
liver FASN
Mean 136
Standard deviation 1e+02
Values 2.8e+02 1.2e+02 92 54
[183]
ref_hepatocyte LSS
Mean 16.9
Standard deviation 8
Values 11 14 12 31 16
[184]
HepG2 LSS
Mean 23.9
Standard deviation 12
Values 32 15
[185]
HepG2.C3A LSS
Mean 91.2
Standard deviation 46
Values 59 1.2e+02
[186]
HuH.7 LSS
Mean 42.1
Standard deviation 4.8
Values 39 48 40
[187]
SNU475 LSS
Mean 16.7
Standard deviation 8.9
Values 10 23
[188]
THLE LSS
Mean 14.1
Standard deviation 4.1
Values 11 17
[189]
liver LSS
Mean 49.9
Standard deviation 22
Values 83 44 39 34
[190]
ref_hepatocyte HSD17B7
Mean 14.9
Standard deviation 12
Values 4 12 35 14 8.9
[191]
HepG2 HSD17B7
Mean 3.52
Standard deviation 0.97
Values 4.2 2.8
[192]
HepG2.C3A HSD17B7
Mean 11.3
Standard deviation 3.5
Values 8.9 14
[193]
HuH.7 HSD17B7
Mean 11.1
Standard deviation 1.6
Values 11 13 9.5
[194]
SNU475 HSD17B7
Mean 2.62
Standard deviation 1.2
Values 1.7 3.5
[195]
THLE HSD17B7
Mean 2.28
Standard deviation 0.47
Values 1.9 2.6
[196]
liver HSD17B7
Mean 12.3
Standard deviation 4.1
Values 15 6.2 15 13
[197]
ref_hepatocyte HMGCR
Mean 14.8
Standard deviation 13
Values 9.1 9.8 5.9 37 12
[198]
HepG2 HMGCR
Mean 22.2
Standard deviation 14
Values 32 12
[199]
HepG2.C3A HMGCR
Mean 133
Standard deviation 31
Values 1.1e+02 1.5e+02
[200]
HuH.7 HMGCR
Mean 154
Standard deviation 61
Values 1.1e+02 2.2e+02 1.3e+02
[201]
SNU475 HMGCR
Mean 22
Standard deviation 2.5
Values 20 24
[202]
THLE HMGCR
Mean 19.8
Standard deviation 3.5
Values 17 22
[203]
liver HMGCR
Mean 54.5
Standard deviation 28
Values 81 71 20 46
[204]
ref_hepatocyte NR1H3
Mean 14.8
Standard deviation 10
Values 6.4 29 22 6.4 9.6
[205]
HepG2 NR1H3
Mean 10.3
Standard deviation 0.1
Values 10 10
[206]
HepG2.C3A NR1H3
Mean 18.6
Standard deviation 4.7
Values 15 22
[207]
HuH.7 NR1H3
Mean 33.8
Standard deviation 2.7
Values 35 36 31
[208]
SNU475 NR1H3
Mean 4.08
Standard deviation 1.1
Values 4.8 3.3
[209]
THLE NR1H3
Mean 1.8
Standard deviation 0.21
Values 1.7 1.9
[210]
liver NR1H3
Mean 16.9
Standard deviation 7.5
Values 9.7 12 25 21
[211]
ref_hepatocyte MVK
Mean 14.5
Standard deviation 7.2
Values 7.9 24 20 12 8.7
[212]
HepG2 MVK
Mean 6.45
Standard deviation 1.7
Values 7.6 5.3
[213]
HepG2.C3A MVK
Mean 29.6
Standard deviation 8.4
Values 24 36
[214]
HuH.7 MVK
Mean 19.4
Standard deviation 2
Values 22 18 19
[215]
SNU475 MVK
Mean 2.86
Standard deviation 0.47
Values 2.5 3.2
[216]
THLE MVK
Mean 2.76
Standard deviation 0.64
Values 2.3 3.2
[217]
liver MVK
Mean 24.4
Standard deviation 13
Values 16 11 36 35
[218]
ref_hepatocyte NR1H2
Mean 12.9
Standard deviation 7.5
Values 19 14 20 2.8 8
[219]
HepG2 NR1H2
Mean 17.7
Standard deviation 3.5
Values 15 20
[220]
HepG2.C3A NR1H2
Mean 14.5
Standard deviation 1.7
Values 13 16
[221]
HuH.7 NR1H2
Mean 17.9
Standard deviation 2.7
Values 20 15 19
[222]
SNU475 NR1H2
Mean 19.9
Standard deviation 0.35
Values 20 20
[223]
THLE NR1H2
Mean 28.5
Standard deviation 1.7
Values 27 30
[224]
liver NR1H2
Mean 18.5
Standard deviation 8.5
Values 11 11 27 25
[225]
ref_hepatocyte ELOVL2
Mean 11.4
Standard deviation 14
Values 0.76 10 3.6 36 6.9
[226]
HepG2 ELOVL2
Mean 25.1
Standard deviation 4.4
Values 28 22
[227]
HepG2.C3A ELOVL2
Mean 78.4
Standard deviation 3.4
Values 81 76
[228]
HuH.7 ELOVL2
Mean 30.6
Standard deviation 8.3
Values 24 40 28
[229]
SNU475 ELOVL2
Mean 5.74
Standard deviation 0.25
Values 5.6 5.9
[230]
THLE ELOVL2
Mean 1.56
Standard deviation 0.62
Values 2 1.1
[231]
liver ELOVL2
Mean 18.3
Standard deviation 11
Values 24 7.1 32 11
[232]
ref_hepatocyte LBR
Mean 10.7
Standard deviation 5.2
Values 7.4 8.2 5.9 18 14
[233]
HepG2 LBR
Mean 39.5
Standard deviation 2.4
Values 41 38
[234]
HepG2.C3A LBR
Mean 57.7
Standard deviation 9.9
Values 65 51
[235]
HuH.7 LBR
Mean 99.9
Standard deviation 21
Values 1e+02 78 1.2e+02
[236]
SNU475 LBR
Mean 49.8
Standard deviation 4.3
Values 47 53
[237]
THLE LBR
Mean 28.8
Standard deviation 2.8
Values 27 31
[238]
liver LBR
Mean 26.2
Standard deviation 6.9
Values 18 28 24 35
[239]
ref_hepatocyte SREBF2
Mean 9.95
Standard deviation 4.6
Values 17 11 9.9 5 6.7
[240]
HepG2 SREBF2
Mean 52.8
Standard deviation 5.8
Values 49 57
[241]
HepG2.C3A SREBF2
Mean 84.4
Standard deviation 47
Values 51 1.2e+02
[242]
HuH.7 SREBF2
Mean 184
Standard deviation 38
Values 1.4e+02 2.2e+02 1.9e+02
[243]
SNU475 SREBF2
Mean 14.5
Standard deviation 9
Values 8.1 21
[244]
THLE SREBF2
Mean 19.8
Standard deviation 7.5
Values 14 25
[245]
liver SREBF2
Mean 39.3
Standard deviation 16
Values 59 46 23 30
[246]
ref_hepatocyte ACSL4
Mean 8.43
Standard deviation 12
Values 4.9 1.3 2.5 30 3.6
[247]
HepG2 ACSL4
Mean 122
Standard deviation 39
Values 1.5e+02 95
[248]
HepG2.C3A ACSL4
Mean 362
Standard deviation 36
Values 3.4e+02 3.9e+02
[249]
HuH.7 ACSL4
Mean 426
Standard deviation 72
Values 3.5e+02 4.5e+02 4.8e+02
[250]
SNU475 ACSL4
Mean 45.3
Standard deviation 4
Values 48 42
[251]
THLE ACSL4
Mean 90.2
Standard deviation 2.5
Values 92 88
[252]
liver ACSL4
Mean 23.4
Standard deviation 10
Values 28 34 11 20
[253]
ref_hepatocyte ABCA1
Mean 4.97
Standard deviation 4
Values 0.95 10 5.2 7.4 1.1
[254]
HepG2 ABCA1
Mean 34.8
Standard deviation 18
Values 48 22
[255]
HepG2.C3A ABCA1
Mean 58.2
Standard deviation 2.3
Values 60 57
[256]
HuH.7 ABCA1
Mean 47.7
Standard deviation 23
Values 26 73 44
[257]
SNU475 ABCA1
Mean 21.2
Standard deviation 3.5
Values 24 19
[258]
THLE ABCA1
Mean 35.1
Standard deviation 5.6
Values 39 31
[259]
liver ABCA1
Mean 262
Standard deviation 1.4e+02
Values 4.4e+02 2.8e+02 2.1e+02 1.2e+02
[260]
ref_hepatocyte SOAT1
Mean 4.02
Standard deviation 3.9
Values 0.73 2.8 2.5 11 3.3
[261]
HepG2 SOAT1
Mean 18
Standard deviation 7.3
Values 23 13
[262]
HepG2.C3A SOAT1
Mean 23.4
Standard deviation 4.3
Values 26 20
[263]
HuH.7 SOAT1
Mean 38.5
Standard deviation 5
Values 36 36 44
[264]
SNU475 SOAT1
Mean 55.4
Standard deviation 0.022
Values 55 55
[265]
THLE SOAT1
Mean 47.6
Standard deviation 11
Values 40 56
[266]
liver SOAT1
Mean 18.1
Standard deviation 2.1
Values 18 21 17 16
[267]
ref_hepatocyte GGPS1
Mean 3.62
Standard deviation 1.6
Values 2.9 3.2 3.1 6.4 2.5
[268]
HepG2 GGPS1
Mean 9.28
Standard deviation 2.3
Values 11 7.6
[269]
HepG2.C3A GGPS1
Mean 19.7
Standard deviation 0.38
Values 19 20
[270]
HuH.7 GGPS1
Mean 18.5
Standard deviation 0.7
Values 19 18 18
[271]
SNU475 GGPS1
Mean 20.3
Standard deviation 4.3
Values 17 23
[272]
THLE GGPS1
Mean 7.32
Standard deviation 0.42
Values 7.6 7
[273]
liver GGPS1
Mean 6.56
Standard deviation 3.2
Values 3.3 4.6 10 8.2
[274]
ref_hepatocyte SOAT2
Mean 1.25
Standard deviation 1.8
Values 0.4 1.1 0.34 4.4 0
[275]
HepG2 SOAT2
Mean 6.93
Standard deviation 0.014
Values 6.9 6.9
[276]
HepG2.C3A SOAT2
Mean 34.3
Standard deviation 14
Values 25 44
[277]
HuH.7 SOAT2
Mean 13
Standard deviation 2.2
Values 13 15 11
[278]
SNU475 SOAT2
Mean 0.0293
Standard deviation 0.0087
Values 0.035 0.023
[279]
THLE SOAT2
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[280]
liver SOAT2
Mean 0.7
Standard deviation 0.61
Values 0.56 0.29 1.6 0.36
[281]
ref_hepatocyte ABCG1
Mean 0.617
Standard deviation 0.67
Values 0.5 1.1 1.5 0 0
[282]
HepG2 ABCG1
Mean 0.677
Standard deviation 0.72
Values 0.17 1.2
[283]
HepG2.C3A ABCG1
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[284]
HuH.7 ABCG1
Mean 0.48
Standard deviation 0.39
Values 0.26 0.93 0.25
[285]
SNU475 ABCG1
Mean 0.0253
Standard deviation 0.036
Values 0.051 0
[286]
THLE ABCG1
Mean 0.966
Standard deviation 0.3
Values 1.2 0.76
[287]
liver ABCG1
Mean 3.31
Standard deviation 1.2
Values 3.9 4.6 1.9 2.8
[288]
ref_hepatocyte MYLIP
Mean 0.452
Standard deviation 0.49
Values 0 0.37 0.59 1.2 0.078
[289]
HepG2 MYLIP
Mean 3.97
Standard deviation 0.79
Values 3.4 4.5
[290]
HepG2.C3A MYLIP
Mean 2.96
Standard deviation 0.36
Values 2.7 3.2
[291]
HuH.7 MYLIP
Mean 5.4
Standard deviation 0.39
Values 5.1 5.8 5.3
[292]
SNU475 MYLIP
Mean 3.43
Standard deviation 0.94
Values 4.1 2.8
[293]
THLE MYLIP
Mean 2.83
Standard deviation 0.44
Values 3.1 2.5
[294]
liver MYLIP
Mean 2.62
Standard deviation 0.45
Values 2.9 2.8 2.8 2
[295]
ref_hepatocyte ELOVL4
Mean 0.0947
Standard deviation 0.15
Values 0.36 0.081 0 0 0.036
[296]
HepG2 ELOVL4
Mean 0.0895
Standard deviation 0.036
Values 0.064 0.11
[297]
HepG2.C3A ELOVL4
Mean 0
Standard deviation 0
Values 0 0
[298]
HuH.7 ELOVL4
Mean 0.0351
Standard deviation 0.018
Values 0.037 0.051 0.016
[299]
SNU475 ELOVL4
Mean 0.398
Standard deviation 0.18
Values 0.52 0.27
[300]
THLE ELOVL4
Mean 3.43
Standard deviation 0.48
Values 3.1 3.8
[301]
liver ELOVL4
Mean 0.0751
Standard deviation 0.08
Values 0.026 0 0.094 0.18
[302]
ref_hepatocyte CYP46A1
Mean 0.0447
Standard deviation 0.068
Values 0 0.15 0.069 0 0
[303]
HepG2 CYP46A1
Mean 0.00716
Standard deviation 0.002
Values 0.0086 0.0057
[304]
HepG2.C3A CYP46A1
Mean 0.0161
Standard deviation 0.023
Values 0.032 0
[305]
HuH.7 CYP46A1
Mean 0.00761
Standard deviation 0.0083
Values 0 0.0064 0.016
[306]
SNU475 CYP46A1
Mean 0.0139
Standard deviation 0.02
Values 0 0.028
[307]
THLE CYP46A1
Mean 0.0358
Standard deviation 0.017
Values 0.024 0.048
[308]
liver CYP46A1
Mean 0.303
Standard deviation 0.093
Values 0.3 0.17 0.38 0.36
[309]
ref_hepatocyte ELOVL3
Mean 0.0431
Standard deviation 0.096
Values 0 0 0.22 0 0
[310]
HepG2 ELOVL3
Mean 0.839
Standard deviation 0.046
Values 0.81 0.87
[311]
HepG2.C3A ELOVL3
Mean 0.494
Standard deviation 0.12
Values 0.58 0.41
[312]
HuH.7 ELOVL3
Mean 0.547
Standard deviation 0.3
Values 0.87 0.28 0.49
[313]
SNU475 ELOVL3
Mean 0.0834
Standard deviation 0.033
Values 0.11 0.06
[314]
THLE ELOVL3
Mean 1.46
Standard deviation 0.1
Values 1.5 1.4
[315]
liver ELOVL3
Mean 0
Standard deviation 0
Values 0 0 0 0
[316]
ref_hepatocyte CH25H
Mean 0.0114
Standard deviation 0.025
Values 0 0.057 0 0 0
[317]
HepG2 CH25H
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[318]
HepG2.C3A CH25H
Mean 0
Standard deviation 0
Values 0 0
[319]
HuH.7 CH25H
Mean 0.00312
Standard deviation 0.0054
Values 0.0094 0 0
[320]
SNU475 CH25H
Mean 6.24
Standard deviation 0.89
Values 6.9 5.6
[321]
THLE CH25H
Mean 0.0766
Standard deviation 0.05
Values 0.041 0.11
[322]
liver CH25H
Mean 0.138
Standard deviation 0.14
Values 0.026 0.014 0.28 0.23
[323]
ref_hepatocyte MIR1908
Missing
[324]
HepG2 MIR1908
Mean 0
Standard deviation 0
Values 0 0
[325]
HepG2.C3A MIR1908
Mean 0
Standard deviation 0
Values 0 0
[326]
HuH.7 MIR1908
Mean 0.0191
Standard deviation 0.008
Values 0.028 0.013 0.016
[327]
SNU475 MIR1908
Mean 0
Standard deviation 0
Values 0 0
[328]
THLE MIR1908
Mean 0
Standard deviation 0
Values 0 0
[329]
liver MIR1908
Mean 0
Standard deviation 0
Values 0 0 0 0
[330]
ref_hepatocyte SC5D
Missing
[331]
HepG2 SC5D
Missing
[332]
HepG2.C3A SC5D
Missing
[333]
HuH.7 SC5D
Missing
[334]
SNU475 SC5D
Missing
[335]
THLE SC5D
Missing
[336]
liver SC5D
Missing