WP_CHOLESTEROL_BIOSYNTHESIS_WITH_SKELETAL_DYSPLASIAS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase [1] -2.82[2] -2.02[3] -1.57[4] -2.26[5] -1.66[6] -2.07[7]
2 DHCR24 Delta(24)-sterol reductase [8] 0.92[9] 0.62[10] 0.60[11] -0.11[12] 0.56[13] 0.86[14]
3 CYP51A1 Lanosterol 14-alpha demethylase [15] -1.22[16] -0.02[17] -0.45[18] 0.06[19] -0.39[20] 0.13[21]
4 DHCR7 7-dehydrocholesterol reductase [22] 0.47[23] 1.01[24] 0.90[25] -0.14[26] -0.02[27] 0.45[28]
5 NSDHL Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating [29] -0.34[30] -0.56[31] -1.53[32] 0.71[33] 0.04[34] -1.34[35]
6 LBR Lamin-B receptor [36] 2.22[37] 1.74[38] 2.23[39] 3.83[40] 2.76[41] 0.11[42]
7 SC5D Lathosterol oxidase [43] [44] [45] [46] [47] [48] [49]
[1]
ref_hepatocyte EBP
Mean 181
Standard deviation 65
Values 1e+02 1.9e+02 1.5e+02 1.8e+02 2.8e+02
[2]
HepG2 EBP
Mean 20.1
Standard deviation 4.7
Values 23 17
[3]
HepG2.C3A EBP
Mean 71.4
Standard deviation 13
Values 63 80
[4]
HuH.7 EBP
Mean 120
Standard deviation 17
Values 1.4e+02 1.1e+02 1.1e+02
[5]
SNU475 EBP
Mean 12.4
Standard deviation 1.5
Values 13 11
[6]
THLE EBP
Mean 22.6
Standard deviation 3.6
Values 20 25
[7]
liver EBP
Mean 97.6
Standard deviation 78
Values 37 24 1.8e+02 1.5e+02
[8]
ref_hepatocyte DHCR24
Mean 160
Standard deviation 83
Values 44 2.6e+02 2e+02 1.8e+02 1.1e+02
[9]
HepG2 DHCR24
Mean 239
Standard deviation 90
Values 3e+02 1.8e+02
[10]
HepG2.C3A DHCR24
Mean 395
Standard deviation 1.3e+02
Values 3e+02 4.9e+02
[11]
HuH.7 DHCR24
Mean 482
Standard deviation 1.1e+02
Values 3.7e+02 5.9e+02 4.9e+02
[12]
SNU475 DHCR24
Mean 48.6
Standard deviation 27
Values 29 68
[13]
THLE DHCR24
Mean 93.2
Standard deviation 28
Values 73 1.1e+02
[14]
liver DHCR24
Mean 661
Standard deviation 1.8e+02
Values 5.3e+02 6.7e+02 5.4e+02 9.1e+02
[15]
ref_hepatocyte CYP51A1
Mean 63
Standard deviation 38
Values 38 46 27 1.2e+02 88
[16]
HepG2 CYP51A1
Mean 21.2
Standard deviation 5.5
Values 25 17
[17]
HepG2.C3A CYP51A1
Mean 99.9
Standard deviation 49
Values 66 1.3e+02
[18]
HuH.7 CYP51A1
Mean 91.5
Standard deviation 23
Values 78 1.2e+02 79
[19]
SNU475 CYP51A1
Mean 21.5
Standard deviation 2.5
Values 20 23
[20]
THLE CYP51A1
Mean 19
Standard deviation 1.2
Values 18 20
[21]
liver CYP51A1
Mean 156
Standard deviation 52
Values 1.5e+02 1.8e+02 89 2.1e+02
[22]
ref_hepatocyte DHCR7
Mean 31.8
Standard deviation 19
Values 23 59 43 21 13
[23]
HepG2 DHCR7
Mean 34.7
Standard deviation 11
Values 43 27
[24]
HepG2.C3A DHCR7
Mean 103
Standard deviation 68
Values 54 1.5e+02
[25]
HuH.7 DHCR7
Mean 117
Standard deviation 29
Values 90 1.5e+02 1.1e+02
[26]
SNU475 DHCR7
Mean 9.4
Standard deviation 1.9
Values 8 11
[27]
THLE DHCR7
Mean 12.4
Standard deviation 3.1
Values 10 15
[28]
liver DHCR7
Mean 98.2
Standard deviation 72
Values 68 50 69 2.1e+02
[29]
ref_hepatocyte NSDHL
Mean 19.7
Standard deviation 8
Values 12 24 31 14 17
[30]
HepG2 NSDHL
Mean 12.3
Standard deviation 4.3
Values 15 9.2
[31]
HepG2.C3A NSDHL
Mean 21.5
Standard deviation 0.63
Values 21 22
[32]
HuH.7 NSDHL
Mean 13.6
Standard deviation 1.6
Values 15 12 14
[33]
SNU475 NSDHL
Mean 10.5
Standard deviation 1
Values 9.8 11
[34]
THLE NSDHL
Mean 8.01
Standard deviation 1.5
Values 6.9 9.1
[35]
liver NSDHL
Mean 17.7
Standard deviation 6.5
Values 15 11 18 26
[36]
ref_hepatocyte LBR
Mean 10.7
Standard deviation 5.2
Values 7.4 8.2 5.9 18 14
[37]
HepG2 LBR
Mean 39.5
Standard deviation 2.4
Values 41 38
[38]
HepG2.C3A LBR
Mean 57.7
Standard deviation 9.9
Values 65 51
[39]
HuH.7 LBR
Mean 99.9
Standard deviation 21
Values 1e+02 78 1.2e+02
[40]
SNU475 LBR
Mean 49.8
Standard deviation 4.3
Values 47 53
[41]
THLE LBR
Mean 28.8
Standard deviation 2.8
Values 27 31
[42]
liver LBR
Mean 26.2
Standard deviation 6.9
Values 18 28 24 35
[43]
ref_hepatocyte SC5D
Missing
[44]
HepG2 SC5D
Missing
[45]
HepG2.C3A SC5D
Missing
[46]
HuH.7 SC5D
Missing
[47]
SNU475 SC5D
Missing
[48]
THLE SC5D
Missing
[49]
liver SC5D
Missing