WP_CEREBRAL_ORGANIC_ACIDURIAS_INCLUDING_DISEASES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 IDH2 Isocitrate dehydrogenase [NADP], mitochondrial [1] -0.64[2] -0.80[3] -0.61[4] -0.83[5] -1.75[6] -0.10[7]
2 MDH2 Malate dehydrogenase, mitochondrial [8] 0.30[9] 0.00[10] 0.22[11] 0.44[12] 0.28[13] -0.26[14]
3 GCDH Glutaryl-CoA dehydrogenase, mitochondrial [15] -1.71[16] -0.71[17] -0.42[18] -2.77[19] -1.20[20] -0.57[21]
4 ALDH7A1 Alpha-aminoadipic semialdehyde dehydrogenase [22] 2.05[23] 2.17[24] 1.71[25] 1.93[26] 2.70[27] 0.50[28]
5 ADHFE1 Hydroxyacid-oxoacid transhydrogenase, mitochondrial [29] -5.52[30] -8.45[31] -1.14[32] -3.22[33] -3.43[34] 0.82[35]
6 D2HGDH D-2-hydroxyglutarate dehydrogenase, mitochondrial [36] 1.93[37] 2.72[38] -0.30[39] 1.72[40] 0.76[41] 0.49[42]
7 L2HGDH L-2-hydroxyglutarate dehydrogenase, mitochondrial [43] 0.79[44] 1.99[45] 2.62[46] 2.65[47] 3.14[48] 3.22[49]
[1]
ref_hepatocyte IDH2
Mean 157
Standard deviation 1.1e+02
Values 30 2.4e+02 2.6e+02 2e+02 52
[2]
HepG2 IDH2
Mean 85
Standard deviation 1.2
Values 84 86
[3]
HepG2.C3A IDH2
Mean 59.2
Standard deviation 12
Values 51 68
[4]
HuH.7 IDH2
Mean 77.5
Standard deviation 6.5
Values 79 70 83
[5]
SNU475 IDH2
Mean 40.8
Standard deviation 22
Values 26 56
[6]
THLE IDH2
Mean 18.2
Standard deviation 1.2
Values 17 19
[7]
liver IDH2
Mean 181
Standard deviation 68
Values 1.4e+02 1.1e+02 2.1e+02 2.6e+02
[8]
ref_hepatocyte MDH2
Mean 104
Standard deviation 75
Values 77 1.3e+02 2.2e+02 38 53
[9]
HepG2 MDH2
Mean 107
Standard deviation 16
Values 96 1.2e+02
[10]
HepG2.C3A MDH2
Mean 67.7
Standard deviation 5.8
Values 64 72
[11]
HuH.7 MDH2
Mean 91.1
Standard deviation 31
Values 98 57 1.2e+02
[12]
SNU475 MDH2
Mean 64.7
Standard deviation 14
Values 55 74
[13]
THLE MDH2
Mean 49
Standard deviation 8.8
Values 43 55
[14]
liver MDH2
Mean 107
Standard deviation 92
Values 29 26 1.7e+02 2e+02
[15]
ref_hepatocyte GCDH
Mean 35.5
Standard deviation 31
Values 4.7 82 49 27 14
[16]
HepG2 GCDH
Mean 9.16
Standard deviation 0.58
Values 9.6 8.7
[17]
HepG2.C3A GCDH
Mean 14.3
Standard deviation 0.91
Values 14 15
[18]
HuH.7 GCDH
Mean 20
Standard deviation 9.2
Values 27 9.5 23
[19]
SNU475 GCDH
Mean 2.41
Standard deviation 0.62
Values 2 2.8
[20]
THLE GCDH
Mean 6.01
Standard deviation 1
Values 5.3 6.7
[21]
liver GCDH
Mean 29.4
Standard deviation 20
Values 16 11 56 34
[22]
ref_hepatocyte ALDH7A1
Mean 17.3
Standard deviation 15
Values 1 39 16 24 6.2
[23]
HepG2 ALDH7A1
Mean 60.1
Standard deviation 16
Values 72 49
[24]
HepG2.C3A ALDH7A1
Mean 51.1
Standard deviation 14
Values 61 41
[25]
HuH.7 ALDH7A1
Mean 42.6
Standard deviation 10
Values 49 31 48
[26]
SNU475 ALDH7A1
Mean 30.3
Standard deviation 10
Values 23 38
[27]
THLE ALDH7A1
Mean 43.7
Standard deviation 3.2
Values 41 46
[28]
liver ALDH7A1
Mean 30
Standard deviation 18
Values 14 17 50 40
[29]
ref_hepatocyte ADHFE1
Mean 10.7
Standard deviation 15
Values 1.6 36 15 0.12 0.8
[30]
HepG2 ADHFE1
Mean 0.196
Standard deviation 0.023
Values 0.18 0.21
[31]
HepG2.C3A ADHFE1
Mean 0.0199
Standard deviation 0.013
Values 0.011 0.029
[32]
HuH.7 ADHFE1
Mean 3.65
Standard deviation 0.82
Values 3.7 4.4 2.8
[33]
SNU475 ADHFE1
Mean 0.529
Standard deviation 0.27
Values 0.34 0.72
[34]
THLE ADHFE1
Mean 0.386
Standard deviation 0.13
Values 0.48 0.29
[35]
liver ADHFE1
Mean 23.1
Standard deviation 19
Values 5.2 8.7 43 36
[36]
ref_hepatocyte D2HGDH
Mean 4.09
Standard deviation 2.1
Values 1.9 6.3 6.3 2.2 3.8
[37]
HepG2 D2HGDH
Mean 13.1
Standard deviation 1.2
Values 14 12
[38]
HepG2.C3A D2HGDH
Mean 17.7
Standard deviation 5.9
Values 14 22
[39]
HuH.7 D2HGDH
Mean 2.51
Standard deviation 0.83
Values 3.4 1.7 2.4
[40]
SNU475 D2HGDH
Mean 6.21
Standard deviation 3.9
Values 3.4 9
[41]
THLE D2HGDH
Mean 2.7
Standard deviation 0.067
Values 2.7 2.7
[42]
liver D2HGDH
Mean 7.07
Standard deviation 3.8
Values 12 8.8 4 3.8
[43]
ref_hepatocyte L2HGDH
Mean 2.59
Standard deviation 1
Values 1.6 3.5 2.4 1.6 3.8
[44]
HepG2 L2HGDH
Mean 3.77
Standard deviation 0.97
Values 4.5 3.1
[45]
HepG2.C3A L2HGDH
Mean 6.76
Standard deviation 1
Values 7.5 6
[46]
HuH.7 L2HGDH
Mean 12
Standard deviation 1.4
Values 12 11 14
[47]
SNU475 L2HGDH
Mean 7.48
Standard deviation 0.089
Values 7.5 7.4
[48]
THLE L2HGDH
Mean 8.88
Standard deviation 0.1
Values 8.8 9
[49]
liver L2HGDH
Mean 29.7
Standard deviation 24
Values 47 54 9 9.1