WP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 [1] -2.44[2] -4.17[3] -2.11[4] -0.41[5] -0.84[6] -0.75[7]
2 GNAQ Guanine nucleotide-binding protein G(q) subunit alpha [8] -0.72[9] -0.73[10] -0.30[11] -0.04[12] 0.37[13] -0.14[14]
3 PLCB1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [15] 2.00[16] 2.83[17] 2.18[18] -0.85[19] -0.16[20] 0.91[21]
4 CCK Cholecystokinin [22] -8.73[23] [24] [25] -6.67[26] -5.96[27] -7.31[28]
5 CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 [29] -9.26[30] [31] -6.66[32] -5.27[33] -3.97[34] -0.67[35]
6 TRPC1 Short transient receptor potential channel 1 [36] 1.28[37] 1.81[38] 1.91[39] 1.42[40] 1.63[41] -1.64[42]
7 ITPR1 Inositol 1,4,5-trisphosphate receptor type 1 [43] 2.34[44] 1.44[45] 2.51[46] 1.23[47] 2.29[48] 3.07[49]
8 DAGLA Sn1-specific diacylglycerol lipase alpha [50] 3.90[51] 2.38[52] 1.97[53] 1.96[54] 2.69[55] -0.39[56]
9 RYR1 Ryanodine receptor 1 [57] 0.69[58] -4.16[59] -2.04[60] 1.78[61] 0.59[62] 3.32[63]
10 RYR3 Ryanodine receptor 3 [64] 3.18[65] 3.44[66] 1.21[67] 4.46[68] 3.54[69] 5.18[70]
11 RYR2 Ryanodine receptor 2 [71] 2.05[72] -0.98[73] 1.41[74] 3.23[75] 1.11[76] 7.33[77]
12 CCKBR Gastrin/cholecystokinin type B receptor [78] [79] [80] [81] [82] [83] [84]
13 CNR1 Cannabinoid receptor 1 [85] [86] [87] [88] [89] [90] [91]
[1]
ref_hepatocyte GNAI1
Mean 6.48
Standard deviation 1.5
Values 6.3 6 4.7 6.5 8.9
[2]
HepG2 GNAI1
Mean 4.56
Standard deviation 1
Values 3.9 5.3
[3]
HepG2.C3A GNAI1
Mean 2.12
Standard deviation 0.54
Values 2.5 1.7
[4]
HuH.7 GNAI1
Mean 8.95
Standard deviation 1.2
Values 10 7.6 9.3
[5]
SNU475 GNAI1
Mean 27.6
Standard deviation 3.4
Values 25 30
[6]
THLE GNAI1
Mean 20
Standard deviation 0.41
Values 20 20
[7]
liver GNAI1
Mean 16.4
Standard deviation 11
Values 9 8.4 32 17
[8]
ref_hepatocyte GNAQ
Mean 1.88
Standard deviation 1
Values 3.6 1.1 1.1 1.6 2
[9]
HepG2 GNAQ
Mean 4.36
Standard deviation 1.2
Values 5.2 3.5
[10]
HepG2.C3A GNAQ
Mean 6.67
Standard deviation 0.93
Values 7.3 6
[11]
HuH.7 GNAQ
Mean 9.12
Standard deviation 3.7
Values 4.8 11 11
[12]
SNU475 GNAQ
Mean 10.4
Standard deviation 1.4
Values 9.4 11
[13]
THLE GNAQ
Mean 13.5
Standard deviation 3.4
Values 11 16
[14]
liver GNAQ
Mean 7.23
Standard deviation 3.8
Values 9.6 11 5.1 3
[15]
ref_hepatocyte PLCB1
Mean 0.993
Standard deviation 1.3
Values 0.37 0.52 0.15 3.2 0.71
[16]
HepG2 PLCB1
Mean 15.2
Standard deviation 2.6
Values 17 13
[17]
HepG2.C3A PLCB1
Mean 41.8
Standard deviation 4.5
Values 39 45
[18]
HuH.7 PLCB1
Mean 26.9
Standard deviation 8.9
Values 19 36 26
[19]
SNU475 PLCB1
Mean 3.13
Standard deviation 0.39
Values 2.9 3.4
[20]
THLE PLCB1
Mean 4.93
Standard deviation 0.69
Values 5.4 4.4
[21]
liver PLCB1
Mean 7.93
Standard deviation 2.5
Values 6 11 8.6 6
[22]
ref_hepatocyte CCK
Mean 0.95
Standard deviation 2.1
Values 4.8 0 0 0 0
[23]
HepG2 CCK
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[24]
HepG2.C3A CCK
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 CCK
Mean 0
Standard deviation 0
Values 0 0 0
[26]
SNU475 CCK
Mean 0.0528
Standard deviation 0.062
Values 0.096 0.0093
[27]
THLE CCK
Mean 0.0846
Standard deviation 0.014
Values 0.095 0.074
[28]
liver CCK
Mean 0.0255
Standard deviation 0.022
Values 0.053 0 0.024 0.026
[29]
ref_hepatocyte CD38
Mean 0.801
Standard deviation 1.1
Values 0 2.4 1.5 0 0.08
[30]
HepG2 CD38
Mean 0.00501
Standard deviation 0.001
Values 0.0043 0.0057
[31]
HepG2.C3A CD38
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 CD38
Mean 0.0471
Standard deviation 0.038
Values 0.019 0.09 0.033
[33]
SNU475 CD38
Mean 0.118
Standard deviation 0.1
Values 0.046 0.19
[34]
THLE CD38
Mean 0.283
Standard deviation 0.15
Values 0.39 0.18
[35]
liver CD38
Mean 2.14
Standard deviation 0.61
Values 1.6 2.2 1.8 3
[36]
ref_hepatocyte TRPC1
Mean 0.42
Standard deviation 0.89
Values 0 0 0 2 0.088
[37]
HepG2 TRPC1
Mean 3.91
Standard deviation 0.98
Values 4.6 3.2
[38]
HepG2.C3A TRPC1
Mean 8.7
Standard deviation 1.4
Values 7.7 9.7
[39]
HuH.7 TRPC1
Mean 9.44
Standard deviation 3.8
Values 7.2 14 7.3
[40]
SNU475 TRPC1
Mean 6.37
Standard deviation 2
Values 4.9 7.8
[41]
THLE TRPC1
Mean 7.24
Standard deviation 1.2
Values 8.1 6.4
[42]
liver TRPC1
Mean 0.573
Standard deviation 0.33
Values 1.1 0.5 0.38 0.36
[43]
ref_hepatocyte ITPR1
Mean 0.398
Standard deviation 0.44
Values 0.1 0.25 0.2 1.2 0.25
[44]
HepG2 ITPR1
Mean 7.73
Standard deviation 1.3
Values 6.8 8.7
[45]
HepG2.C3A ITPR1
Mean 6.36
Standard deviation 0.83
Values 5.8 7
[46]
HuH.7 ITPR1
Mean 13.6
Standard deviation 3.5
Values 9.6 16 15
[47]
SNU475 ITPR1
Mean 5.27
Standard deviation 3.4
Values 7.7 2.8
[48]
THLE ITPR1
Mean 10.8
Standard deviation 2.1
Values 12 9.3
[49]
liver ITPR1
Mean 14.2
Standard deviation 12
Values 29 20 4.3 3.8
[50]
ref_hepatocyte DAGLA
Mean 0.182
Standard deviation 0.32
Values 0.073 0.065 0 0.75 0.021
[51]
HepG2 DAGLA
Mean 10.4
Standard deviation 1.4
Values 9.4 11
[52]
HepG2.C3A DAGLA
Mean 5.58
Standard deviation 0.43
Values 5.3 5.9
[53]
HuH.7 DAGLA
Mean 4.26
Standard deviation 1
Values 3.1 5 4.6
[54]
SNU475 DAGLA
Mean 4.01
Standard deviation 1.2
Values 3.1 4.9
[55]
THLE DAGLA
Mean 6.53
Standard deviation 0.77
Values 6 7.1
[56]
liver DAGLA
Mean 0.593
Standard deviation 0.38
Values 1.1 0.73 0.35 0.23
[57]
ref_hepatocyte RYR1
Mean 0.0147
Standard deviation 0.017
Values 0.033 0.033 0.0086 0 0
[58]
HepG2 RYR1
Mean 0.0909
Standard deviation 0.074
Values 0.039 0.14
[59]
HepG2.C3A RYR1
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[60]
HuH.7 RYR1
Mean 0.0214
Standard deviation 0.015
Values 0.0094 0.039 0.016
[61]
SNU475 RYR1
Mean 0.287
Standard deviation 0.12
Values 0.37 0.2
[62]
THLE RYR1
Mean 0.123
Standard deviation 0.074
Values 0.071 0.18
[63]
liver RYR1
Mean 0.627
Standard deviation 0.6
Values 1.2 1.1 0.14 0.077
[64]
ref_hepatocyte RYR3
Mean 0.00335
Standard deviation 0.0046
Values 0 0.0081 0.0086 0 0
[65]
HepG2 RYR3
Mean 0.117
Standard deviation 0.035
Values 0.14 0.092
[66]
HepG2.C3A RYR3
Mean 0.214
Standard deviation 0.014
Values 0.2 0.22
[67]
HuH.7 RYR3
Mean 0.0462
Standard deviation 0.026
Values 0.019 0.071 0.049
[68]
SNU475 RYR3
Mean 0.418
Standard deviation 0.018
Values 0.41 0.43
[69]
THLE RYR3
Mean 0.216
Standard deviation 0.012
Values 0.22 0.21
[70]
liver RYR3
Mean 0.516
Standard deviation 0.31
Values 0.93 0.6 0.28 0.26
[71]
ref_hepatocyte RYR2
Mean 0.00163
Standard deviation 0.0036
Values 0 0.0081 0 0 0
[72]
HepG2 RYR2
Mean 0.0258
Standard deviation 0.036
Values 0 0.052
[73]
HepG2.C3A RYR2
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[74]
HuH.7 RYR2
Mean 0.0258
Standard deviation 0.025
Values 0.028 0 0.049
[75]
SNU475 RYR2
Mean 0.0863
Standard deviation 0.05
Values 0.12 0.051
[76]
THLE RYR2
Mean 0.0195
Standard deviation 0.0025
Values 0.018 0.021
[77]
liver RYR2
Mean 1.11
Standard deviation 1
Values 2.1 1.9 0.28 0.21
[78]
ref_hepatocyte CCKBR
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 CCKBR
Missing
[80]
HepG2.C3A CCKBR
Missing
[81]
HuH.7 CCKBR
Missing
[82]
SNU475 CCKBR
Missing
[83]
THLE CCKBR
Missing
[84]
liver CCKBR
Missing
[85]
ref_hepatocyte CNR1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 CNR1
Mean 0.0315
Standard deviation 0.045
Values 0 0.063
[87]
HepG2.C3A CNR1
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[88]
HuH.7 CNR1
Mean 0.00487
Standard deviation 0.0043
Values 0 0.0064 0.0082
[89]
SNU475 CNR1
Mean 10.9
Standard deviation 7.2
Values 5.8 16
[90]
THLE CNR1
Mean 3.54
Standard deviation 1.8
Values 4.8 2.3
[91]
liver CNR1
Mean 0.247
Standard deviation 0.23
Values 0.6 0.17 0.094 0.13