WP_CANONICAL_AND_NONCANONICAL_TGFB_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TGFBR2 TGF-beta receptor type-2 [1] 0.55[2] 0.40[3] 0.23[4] -1.40[5] 0.09[6] 0.08[7]
2 MAPK14 Mitogen-activated protein kinase 14 [8] -0.79[9] -0.34[10] -0.59[11] -0.78[12] -1.53[13] -0.14[14]
3 MAPK8 Mitogen-activated protein kinase 8 [15] -3.71[16] -1.92[17] -2.87[18] -3.36[19] -3.73[20] -1.93[21]
4 SMAD3 Mothers against decapentaplegic homolog 3 [22] -0.34[23] -0.56[24] -0.15[25] -0.66[26] -0.01[27] -1.21[28]
5 BMP1 Bone morphogenetic protein 1 [29] -1.53[30] -2.65[31] -3.14[32] -0.35[33] -1.16[34] -0.50[35]
6 TGFBR1 TGF-beta receptor type-1 [36] -1.94[37] -1.33[38] -1.65[39] -2.12[40] -1.24[41] -0.09[42]
7 MAPK9 Mitogen-activated protein kinase 9 [43] -1.04[44] -0.44[45] -0.19[46] -0.75[47] -1.52[48] -0.91[49]
8 SMAD4 Mothers against decapentaplegic homolog 4 [50] -0.87[51] 0.13[52] 0.28[53] -0.55[54] -0.41[55] 1.37[56]
9 BMPR1A Bone morphogenetic protein receptor type-1A [57] -0.96[58] 0.06[59] -1.09[60] -1.21[61] -1.17[62] -0.25[63]
10 SMAD2 Mothers against decapentaplegic homolog 2 [64] -0.25[65] 0.39[66] 0.07[67] -0.08[68] -0.11[69] 1.15[70]
11 TGFB1 Transforming growth factor beta-1 [71] 1.21[72] 0.54[73] -2.02[74] 1.38[75] 0.38[76] -2.65[77]
12 LOXL4 Lysyl oxidase homolog 4 [78] 2.66[79] 1.10[80] -4.18[81] -2.37[82] -4.01[83] -2.02[84]
13 BMPR2 Bone morphogenetic protein receptor type-2 [85] 0.92[86] 0.33[87] 1.19[88] 1.67[89] 0.78[90] 2.88[91]
14 GREM1 Gremlin-1 [92] -4.45[93] -5.94[94] -4.19[95] 5.37[96] 1.35[97] -0.96[98]
15 LOXL2 Lysyl oxidase homolog 2 [99] 4.14[100] -1.82[101] -0.30[102] 4.98[103] 5.57[104] 2.09[105]
16 LOX Protein-lysine 6-oxidase [106] 5.54[107] 6.43[108] 7.25[109] 2.79[110] 6.65[111] 2.11[112]
17 LOXL1 Lysyl oxidase homolog 1 [113] -0.60[114] -3.09[115] -1.28[116] 4.58[117] 2.90[118] -1.43[119]
[1]
ref_hepatocyte TGFBR2
Mean 11.1
Standard deviation 9.7
Values 6.4 3.5 4.2 26 15
[2]
HepG2 TGFBR2
Mean 172
Standard deviation 10
Values 1.8e+02 1.7e+02
[3]
HepG2.C3A TGFBR2
Mean 106
Standard deviation 5.8
Values 1e+02 1.1e+02
[4]
HuH.7 TGFBR2
Mean 80.1
Standard deviation 11
Values 77 71 92
[5]
SNU475 TGFBR2
Mean 42.5
Standard deviation 18
Values 55 29
[6]
THLE TGFBR2
Mean 157
Standard deviation 23
Values 1.4e+02 1.7e+02
[7]
liver TGFBR2
Mean 44.6
Standard deviation 11
Values 57 51 31 40
[8]
ref_hepatocyte MAPK14
Mean 8.71
Standard deviation 2
Values 7.2 8.3 7.5 12 8.5
[9]
HepG2 MAPK14
Mean 53.4
Standard deviation 8.7
Values 60 47
[10]
HepG2.C3A MAPK14
Mean 49.9
Standard deviation 0.11
Values 50 50
[11]
HuH.7 MAPK14
Mean 35.7
Standard deviation 1.3
Values 34 36 37
[12]
SNU475 MAPK14
Mean 51.3
Standard deviation 0.4
Values 51 52
[13]
THLE MAPK14
Mean 40
Standard deviation 3.6
Values 37 43
[14]
liver MAPK14
Mean 30.1
Standard deviation 8.3
Values 37 38 24 22
[15]
ref_hepatocyte MAPK8
Mean 7.1
Standard deviation 4.4
Values 15 4.7 3.8 6.5 5.6
[16]
HepG2 MAPK8
Mean 5.76
Standard deviation 1
Values 6.5 5.1
[17]
HepG2.C3A MAPK8
Mean 13.6
Standard deviation 4
Values 17 11
[18]
HuH.7 MAPK8
Mean 5.99
Standard deviation 0.68
Values 5.2 6.2 6.5
[19]
SNU475 MAPK8
Mean 6.98
Standard deviation 0.5
Values 6.6 7.3
[20]
THLE MAPK8
Mean 7.08
Standard deviation 1
Values 6.4 7.8
[21]
liver MAPK8
Mean 7.08
Standard deviation 1
Values 7.6 7.8 7.3 5.6
[22]
ref_hepatocyte SMAD3
Mean 5.99
Standard deviation 4.6
Values 13 2.2 1.9 4.8 8.4
[23]
HepG2 SMAD3
Mean 50.4
Standard deviation 14
Values 40 60
[24]
HepG2.C3A SMAD3
Mean 29.5
Standard deviation 11
Values 22 37
[25]
HuH.7 SMAD3
Mean 33.2
Standard deviation 6.9
Values 28 41 31
[26]
SNU475 SMAD3
Mean 38.2
Standard deviation 2.7
Values 36 40
[27]
THLE SMAD3
Mean 78.9
Standard deviation 8.4
Values 73 85
[28]
liver SMAD3
Mean 9.85
Standard deviation 3
Values 13 7.4 12 7.1
[29]
ref_hepatocyte BMP1
Mean 4.74
Standard deviation 2
Values 4.8 3.8 3.4 3.6 8.1
[30]
HepG2 BMP1
Mean 17.4
Standard deviation 1.6
Values 16 19
[31]
HepG2.C3A BMP1
Mean 5.5
Standard deviation 0.036
Values 5.5 5.5
[32]
HuH.7 BMP1
Mean 3.31
Standard deviation 0.52
Values 3.4 2.7 3.7
[33]
SNU475 BMP1
Mean 37.7
Standard deviation 14
Values 28 47
[34]
THLE BMP1
Mean 28.1
Standard deviation 4
Values 31 25
[35]
liver BMP1
Mean 12.8
Standard deviation 3.2
Values 17 11 12 10
[36]
ref_hepatocyte TGFBR1
Mean 4.72
Standard deviation 3.6
Values 3.6 3.1 1.8 4.2 11
[37]
HepG2 TGFBR1
Mean 13.1
Standard deviation 3.3
Values 15 11
[38]
HepG2.C3A TGFBR1
Mean 13.6
Standard deviation 0.22
Values 14 13
[39]
HuH.7 TGFBR1
Mean 9.25
Standard deviation 2.6
Values 7.2 12 8.3
[40]
SNU475 TGFBR1
Mean 11
Standard deviation 1.8
Values 12 9.7
[41]
THLE TGFBR1
Mean 26.5
Standard deviation 5.3
Values 30 23
[42]
liver TGFBR1
Mean 16.9
Standard deviation 7.4
Values 20 25 8.6 13
[43]
ref_hepatocyte MAPK9
Mean 4.45
Standard deviation 2.7
Values 1.4 3.3 3.7 8.6 5.3
[44]
HepG2 MAPK9
Mean 23
Standard deviation 4.4
Values 26 20
[45]
HepG2.C3A MAPK9
Mean 24
Standard deviation 3.3
Values 26 22
[46]
HuH.7 MAPK9
Mean 24
Standard deviation 2.9
Values 25 21 26
[47]
SNU475 MAPK9
Mean 26.8
Standard deviation 2.4
Values 25 29
[48]
THLE MAPK9
Mean 20.6
Standard deviation 0.2
Values 21 21
[49]
liver MAPK9
Mean 9.01
Standard deviation 3.1
Values 11 12 7.1 5.7
[50]
ref_hepatocyte SMAD4
Mean 3.16
Standard deviation 0.71
Values 4.2 3.4 2.4 2.9 2.8
[51]
HepG2 SMAD4
Mean 18.3
Standard deviation 3.2
Values 21 16
[52]
HepG2.C3A SMAD4
Mean 25.2
Standard deviation 3
Values 23 27
[53]
HuH.7 SMAD4
Mean 23.6
Standard deviation 3.4
Values 20 27 24
[54]
SNU475 SMAD4
Mean 21.8
Standard deviation 2.7
Values 20 24
[55]
THLE SMAD4
Mean 31.4
Standard deviation 1.4
Values 30 32
[56]
liver SMAD4
Mean 31
Standard deviation 13
Values 44 40 23 16
[57]
ref_hepatocyte BMPR1A
Mean 2.74
Standard deviation 2.9
Values 1.1 1.3 1.1 7.9 2.3
[58]
HepG2 BMPR1A
Mean 14.9
Standard deviation 3.9
Values 18 12
[59]
HepG2.C3A BMPR1A
Mean 20.7
Standard deviation 6.3
Values 25 16
[60]
HuH.7 BMPR1A
Mean 7.89
Standard deviation 1.6
Values 6.1 9.2 8.3
[61]
SNU475 BMPR1A
Mean 12
Standard deviation 2.6
Values 10 14
[62]
THLE BMPR1A
Mean 16.1
Standard deviation 2.3
Values 15 18
[63]
liver BMPR1A
Mean 8.77
Standard deviation 4.5
Values 13 12 5.4 4.4
[64]
ref_hepatocyte SMAD2
Mean 2.54
Standard deviation 1.2
Values 1.9 1.6 1.9 4.5 2.8
[65]
HepG2 SMAD2
Mean 22.7
Standard deviation 2.3
Values 24 21
[66]
HepG2.C3A SMAD2
Mean 24.2
Standard deviation 1.1
Values 23 25
[67]
HuH.7 SMAD2
Mean 16.4
Standard deviation 1.6
Values 15 18 17
[68]
SNU475 SMAD2
Mean 24.3
Standard deviation 3.3
Values 22 27
[69]
THLE SMAD2
Mean 31
Standard deviation 0.65
Values 31 32
[70]
liver SMAD2
Mean 21.4
Standard deviation 6.7
Values 25 29 17 15
[71]
ref_hepatocyte TGFB1
Mean 2.22
Standard deviation 1.8
Values 0.92 2.3 1.3 5.3 1.3
[72]
HepG2 TGFB1
Mean 54.4
Standard deviation 32
Values 32 77
[73]
HepG2.C3A TGFB1
Mean 23.6
Standard deviation 8.3
Values 18 29
[74]
HuH.7 TGFB1
Mean 3.37
Standard deviation 1.4
Values 3.7 1.8 4.5
[75]
SNU475 TGFB1
Mean 58.3
Standard deviation 7.8
Values 53 64
[76]
THLE TGFB1
Mean 38.3
Standard deviation 9.8
Values 31 45
[77]
liver TGFB1
Mean 1.34
Standard deviation 0.71
Values 2.3 1.4 1.1 0.62
[78]
ref_hepatocyte LOXL4
Mean 1.19
Standard deviation 0.88
Values 1.5 0.11 2.5 0.8 1
[79]
HepG2 LOXL4
Mean 79.7
Standard deviation 34
Values 56 1e+02
[80]
HepG2.C3A LOXL4
Mean 18.6
Standard deviation 6.7
Values 14 23
[81]
HuH.7 LOXL4
Mean 0.403
Standard deviation 0.33
Values 0.19 0.78 0.24
[82]
SNU475 LOXL4
Mean 2.33
Standard deviation 0.63
Values 1.9 2.8
[83]
THLE LOXL4
Mean 0.975
Standard deviation 0.16
Values 1.1 0.86
[84]
liver LOXL4
Mean 1.11
Standard deviation 0.35
Values 1.2 1.5 0.66 1.1
[85]
ref_hepatocyte BMPR2
Mean 1.09
Standard deviation 0.28
Values 0.88 1.4 1.2 1.2 0.73
[86]
HepG2 BMPR2
Mean 21.8
Standard deviation 5.9
Values 26 18
[87]
HepG2.C3A BMPR2
Mean 9.92
Standard deviation 0.63
Values 10 9.5
[88]
HuH.7 BMPR2
Mean 15.2
Standard deviation 4.2
Values 11 16 19
[89]
SNU475 BMPR2
Mean 35.1
Standard deviation 7.7
Values 30 41
[90]
THLE BMPR2
Mean 24.7
Standard deviation 0.28
Values 25 25
[91]
liver BMPR2
Mean 30.3
Standard deviation 5.5
Values 33 36 29 24
[92]
ref_hepatocyte GREM1
Mean 0.352
Standard deviation 0.29
Values 0.74 0.15 0.54 0 0.33
[93]
HepG2 GREM1
Mean 0.171
Standard deviation 0.09
Values 0.11 0.23
[94]
HepG2.C3A GREM1
Mean 0.0419
Standard deviation 0.032
Values 0.064 0.019
[95]
HuH.7 GREM1
Mean 0.119
Standard deviation 0.092
Values 0.019 0.2 0.14
[96]
SNU475 GREM1
Mean 147
Standard deviation 51
Values 1.1e+02 1.8e+02
[97]
THLE GREM1
Mean 11.9
Standard deviation 0.99
Values 11 13
[98]
liver GREM1
Mean 0.687
Standard deviation 0.75
Values 1.4 0 1.3 0.077
[99]
ref_hepatocyte LOXL2
Mean 0.188
Standard deviation 0.13
Values 0.24 0.25 0.1 0.34 0
[100]
HepG2 LOXL2
Mean 35.2
Standard deviation 37
Values 9.2 61
[101]
HepG2.C3A LOXL2
Mean 0.387
Standard deviation 0.016
Values 0.38 0.4
[102]
HuH.7 LOXL2
Mean 0.939
Standard deviation 0.13
Values 0.8 0.99 1
[103]
SNU475 LOXL2
Mean 59.9
Standard deviation 8.1
Values 54 66
[104]
THLE LOXL2
Mean 118
Standard deviation 9.5
Values 1.3e+02 1.1e+02
[105]
liver LOXL2
Mean 3.04
Standard deviation 1.7
Values 2 4 1.2 5
[106]
ref_hepatocyte LOX
Mean 0.12
Standard deviation 0.14
Values 0 0.19 0.095 0.32 0
[107]
HepG2 LOX
Mean 59.4
Standard deviation 46
Values 27 92
[108]
HepG2.C3A LOX
Mean 75.2
Standard deviation 24
Values 58 92
[109]
HuH.7 LOX
Mean 113
Standard deviation 11
Values 1e+02 1.1e+02 1.2e+02
[110]
SNU475 LOX
Mean 8.37
Standard deviation 4.8
Values 12 5
[111]
THLE LOX
Mean 159
Standard deviation 17
Values 1.5e+02 1.7e+02
[112]
liver LOX
Mean 1.98
Standard deviation 1.1
Values 1 2.7 1 3.2
[113]
ref_hepatocyte LOXL1
Mean 0.116
Standard deviation 0.2
Values 0.46 0.065 0 0.052 0
[114]
HepG2 LOXL1
Mean 0.81
Standard deviation 0.1
Values 0.74 0.88
[115]
HepG2.C3A LOXL1
Mean 0.0989
Standard deviation 0.057
Values 0.14 0.058
[116]
HuH.7 LOXL1
Mean 0.293
Standard deviation 0.15
Values 0.28 0.45 0.15
[117]
SNU475 LOXL1
Mean 28.1
Standard deviation 18
Values 16 41
[118]
THLE LOXL1
Mean 11.4
Standard deviation 2.8
Values 9.5 13
[119]
liver LOXL1
Mean 0.163
Standard deviation 0.12
Values 0.32 0.19 0.047 0.1