WP_CANNABINOID_RECEPTOR_SIGNALING | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CYP2C9 | Cytochrome P450 2C9 | [1] | [2] | -15.11[3] | -8.14[4] | -14.33[5] | -13.35[6] | 0.19[7] |
2 | CYP3A4 | Cytochrome P450 3A4 | [8] | -10.07[9] | -10.31[10] | -11.95[11] | -14.64[12] | -12.93[13] | -0.09[14] |
3 | PRKAR1A | cAMP-dependent protein kinase type I-alpha regulatory subunit | [15] | 1.75[16] | 1.76[17] | 1.98[18] | 1.79[19] | 1.85[20] | -0.23[21] |
4 | CYP1A1 | Cytochrome P450 1A1 | [22] | -2.79[23] | -4.49[24] | -0.76[25] | -3.61[26] | -3.98[27] | -6.62[28] |
5 | CYP2C19 | Cytochrome P450 2C19 | [29] | [30] | [31] | -5.28[32] | -12.01[33] | -11.66[34] | 0.75[35] |
6 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | [36] | 1.51[37] | 1.22[38] | 1.29[39] | 1.41[40] | 2.17[41] | -1.61[42] |
7 | MAPK1 | Mitogen-activated protein kinase 1 | [43] | 3.39[44] | 3.41[45] | 3.31[46] | 3.72[47] | 3.54[48] | 0.95[49] |
8 | MAPK14 | Mitogen-activated protein kinase 14 | [50] | 3.15[51] | 3.11[52] | 2.75[53] | 3.56[54] | 3.20[55] | 0.46[56] |
9 | MAPK8 | Mitogen-activated protein kinase 8 | [57] | 0.23[58] | 1.53[59] | 0.47[60] | 0.97[61] | 1.00[62] | -1.34[63] |
10 | FAAH | Fatty-acid amide hydrolase 1 | [64] | -0.62[65] | 0.45[66] | -2.00[67] | -1.34[68] | -4.33[69] | -0.37[70] |
11 | PRKAR1B | cAMP-dependent protein kinase type I-beta regulatory subunit | [71] | 2.65[72] | 1.99[73] | 0.27[74] | -2.22[75] | 0.74[76] | -1.00[77] |
12 | DAGLB | Sn1-specific diacylglycerol lipase beta | [78] | 1.14[79] | 0.19[80] | 0.85[81] | 1.23[82] | 1.80[83] | -1.30[84] |
13 | MAPK13 | Mitogen-activated protein kinase 13 | [85] | 4.02[86] | 4.31[87] | 1.70[88] | -0.01[89] | 1.68[90] | -2.54[91] |
14 | AHR | Aryl hydrocarbon receptor | [92] | 2.80[93] | 2.98[94] | 4.07[95] | 2.42[96] | 3.50[97] | 1.77[98] |
15 | MAPK9 | Mitogen-activated protein kinase 9 | [99] | 2.90[100] | 3.02[101] | 3.15[102] | 3.59[103] | 3.22[104] | -0.32[105] |
16 | MAPK3 | Mitogen-activated protein kinase 3 | [106] | 3.53[107] | 3.46[108] | 3.57[109] | 2.30[110] | 2.49[111] | -1.87[112] |
17 | PRKACB | cAMP-dependent protein kinase catalytic subunit beta | [113] | 0.84[114] | 1.51[115] | 2.86[116] | 4.11[117] | 3.14[118] | 0.88[119] |
18 | NAPEPLD | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | [120] | 1.24[121] | 2.17[122] | 3.15[123] | 2.77[124] | 1.30[125] | 1.24[126] |
19 | ADORA2A | Adenosine receptor A2a | [127] | 1.10[128] | 1.45[129] | 3.24[130] | 1.27[131] | -0.36[132] | 0.37[133] |
20 | ADCY1 | Adenylate cyclase type 1 | [134] | 0.84[135] | -1.14[136] | -1.27[137] | -0.23[138] | -0.08[139] | 4.17[140] |
21 | MAPK12 | Mitogen-activated protein kinase 12 | [141] | 4.50[142] | 4.05[143] | 5.23[144] | 3.36[145] | 4.78[146] | -1.73[147] |
22 | ADCY7 | Adenylate cyclase type 7 | [148] | 5.19[149] | 4.70[150] | 3.72[151] | 5.18[152] | 4.83[153] | 2.10[154] |
23 | MAPK11 | Mitogen-activated protein kinase 11 | [155] | 1.50[156] | 1.29[157] | 0.47[158] | 2.23[159] | 4.40[160] | -0.66[161] |
24 | DAGLA | Sn1-specific diacylglycerol lipase alpha | [162] | 6.37[163] | 5.53[164] | 5.27[165] | 5.46[166] | 6.17[167] | 0.37[168] |
25 | PRKAR2B | cAMP-dependent protein kinase type II-beta regulatory subunit | [169] | -0.66[170] | 1.05[171] | 5.40[172] | 6.96[173] | 5.65[174] | 2.49[175] |
26 | CNR2 | Cannabinoid receptor 2 | [176] | [177] | [178] | 0.38[179] | [180] | 2.11[181] | 1.12[182] |
27 | MAPK10 | Mitogen-activated protein kinase 10 | [183] | 0.19[184] | [185] | [186] | 10.78[187] | 6.69[188] | 6.42[189] |
28 | CNR1 | Cannabinoid receptor 1 | [190] | [191] | [192] | [193] | [194] | [195] | [196] |
29 | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma | [197] | [198] | [199] | [200] | [201] | [202] | [203] |