WP_BONE_MORPHOGENIC_PROTEIN_BMP_SIGNALING_AND_REGULATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TOB1 Protein Tob1 [1] -1.38[2] -0.88[3] -1.46[4] -1.96[5] -2.67[6] -0.02[7]
2 TOB2 Protein Tob2 [8] 0.60[9] 0.25[10] 0.64[11] -0.08[12] -0.59[13] -0.54[14]
3 BMP2 Bone morphogenetic protein 2 [15] -5.28[16] -8.40[17] 0.30[18] -2.46[19] -2.17[20] -3.68[21]
4 SMAD1 Mothers against decapentaplegic homolog 1 [22] -1.35[23] -1.08[24] -1.19[25] -1.30[26] -0.70[27] -0.87[28]
5 SMURF1 E3 ubiquitin-protein ligase SMURF1 [29] 1.14[30] 0.59[31] 1.11[32] 0.64[33] 0.57[34] -0.11[35]
6 SMAD4 Mothers against decapentaplegic homolog 4 [36] 1.09[37] 1.73[38] 1.30[39] 1.34[40] 1.75[41] 1.29[42]
7 BMPR1A Bone morphogenetic protein receptor type-1A [43] 1.00[44] 1.66[45] -0.07[46] 0.68[47] 0.99[48] -0.32[49]
8 SMAD6 Mothers against decapentaplegic homolog 6 [50] 1.11[51] -0.62[52] -0.59[53] 0.88[54] -0.63[55] -0.64[56]
9 BMPR2 Bone morphogenetic protein receptor type-2 [57] 2.89[58] 1.93[59] 2.21[60] 3.56[61] 2.94[62] 2.80[63]
10 RUNX2 Runt-related transcription factor 2 [64] -1.15[65] -1.49[66] 3.18[67] 6.55[68] 8.55[69] 2.13[70]
11 BMPR1B Bone morphogenetic protein receptor type-1B [71] -1.31[72] -2.13[73] 3.12[74] 5.20[75] 1.89[76] 5.06[77]
12 NOG Noggin [78] [79] [80] [81] [82] [83] [84]
[1]
ref_hepatocyte TOB1
Mean 21.8
Standard deviation 7.8
Values 17 33 18 27 15
[2]
HepG2 TOB1
Mean 22.9
Standard deviation 1.5
Values 22 24
[3]
HepG2.C3A TOB1
Mean 28.5
Standard deviation 2.6
Values 27 30
[4]
HuH.7 TOB1
Mean 24
Standard deviation 2.8
Values 27 22 23
[5]
SNU475 TOB1
Mean 15.3
Standard deviation 0.35
Values 15 16
[6]
THLE TOB1
Mean 10.2
Standard deviation 1.2
Values 9.3 11
[7]
liver TOB1
Mean 86.2
Standard deviation 83
Values 12 18 1.4e+02 1.7e+02
[8]
ref_hepatocyte TOB2
Mean 6.26
Standard deviation 3.9
Values 7.4 3.8 2.9 13 4.7
[9]
HepG2 TOB2
Mean 25.9
Standard deviation 3.5
Values 28 23
[10]
HepG2.C3A TOB2
Mean 17.9
Standard deviation 2.9
Values 16 20
[11]
HuH.7 TOB2
Mean 29.6
Standard deviation 4.1
Values 30 25 33
[12]
SNU475 TOB2
Mean 16.3
Standard deviation 2.6
Values 14 18
[13]
THLE TOB2
Mean 12.4
Standard deviation 3.7
Values 9.8 15
[14]
liver TOB2
Mean 17.3
Standard deviation 4.3
Values 16 12 22 20
[15]
ref_hepatocyte BMP2
Mean 5.74
Standard deviation 7.8
Values 11 0.28 0.49 0 17
[16]
HepG2 BMP2
Mean 0.401
Standard deviation 0.033
Values 0.42 0.38
[17]
HepG2.C3A BMP2
Mean 0.0409
Standard deviation 0.0028
Values 0.043 0.039
[18]
HuH.7 BMP2
Mean 21.5
Standard deviation 8.1
Values 17 31 17
[19]
SNU475 BMP2
Mean 2.85
Standard deviation 0.2
Values 2.7 3
[20]
THLE BMP2
Mean 3.79
Standard deviation 1.9
Values 2.4 5.2
[21]
liver BMP2
Mean 1.79
Standard deviation 0.56
Values 2.4 2.1 1.4 1.3
[22]
ref_hepatocyte SMAD1
Mean 5.73
Standard deviation 2
Values 6.7 7.5 7 2.8 4.6
[23]
HepG2 SMAD1
Mean 6.12
Standard deviation 1.6
Values 7.2 5
[24]
HepG2.C3A SMAD1
Mean 6.51
Standard deviation 0.83
Values 7.1 5.9
[25]
HuH.7 SMAD1
Mean 7.65
Standard deviation 2.8
Values 5.8 11 6.3
[26]
SNU475 SMAD1
Mean 6.35
Standard deviation 0.026
Values 6.3 6.4
[27]
THLE SMAD1
Mean 10.5
Standard deviation 1.5
Values 9.5 12
[28]
liver SMAD1
Mean 12.6
Standard deviation 5.3
Values 11 7.6 20 12
[29]
ref_hepatocyte SMURF1
Mean 3.55
Standard deviation 2.6
Values 7.2 0.92 1.5 3 5.1
[30]
HepG2 SMURF1
Mean 21.3
Standard deviation 3.9
Values 19 24
[31]
HepG2.C3A SMURF1
Mean 12.9
Standard deviation 1.5
Values 12 14
[32]
HuH.7 SMURF1
Mean 23.3
Standard deviation 5.2
Values 18 29 23
[33]
SNU475 SMURF1
Mean 15.1
Standard deviation 1.3
Values 16 14
[34]
THLE SMURF1
Mean 15.7
Standard deviation 2.1
Values 14 17
[35]
liver SMURF1
Mean 13.2
Standard deviation 6
Values 19 18 7.3 8.8
[36]
ref_hepatocyte SMAD4
Mean 3.16
Standard deviation 0.71
Values 4.2 3.4 2.4 2.9 2.8
[37]
HepG2 SMAD4
Mean 18.3
Standard deviation 3.2
Values 21 16
[38]
HepG2.C3A SMAD4
Mean 25.2
Standard deviation 3
Values 23 27
[39]
HuH.7 SMAD4
Mean 23.6
Standard deviation 3.4
Values 20 27 24
[40]
SNU475 SMAD4
Mean 21.8
Standard deviation 2.7
Values 20 24
[41]
THLE SMAD4
Mean 31.4
Standard deviation 1.4
Values 30 32
[42]
liver SMAD4
Mean 31
Standard deviation 13
Values 44 40 23 16
[43]
ref_hepatocyte BMPR1A
Mean 2.74
Standard deviation 2.9
Values 1.1 1.3 1.1 7.9 2.3
[44]
HepG2 BMPR1A
Mean 14.9
Standard deviation 3.9
Values 18 12
[45]
HepG2.C3A BMPR1A
Mean 20.7
Standard deviation 6.3
Values 25 16
[46]
HuH.7 BMPR1A
Mean 7.89
Standard deviation 1.6
Values 6.1 9.2 8.3
[47]
SNU475 BMPR1A
Mean 12
Standard deviation 2.6
Values 10 14
[48]
THLE BMPR1A
Mean 16.1
Standard deviation 2.3
Values 15 18
[49]
liver BMPR1A
Mean 8.77
Standard deviation 4.5
Values 13 12 5.4 4.4
[50]
ref_hepatocyte SMAD6
Mean 1.52
Standard deviation 0.99
Values 2.1 2.7 1.7 0.24 0.85
[51]
HepG2 SMAD6
Mean 8.95
Standard deviation 4.8
Values 5.6 12
[52]
HepG2.C3A SMAD6
Mean 2.39
Standard deviation 0.87
Values 1.8 3
[53]
HuH.7 SMAD6
Mean 3.06
Standard deviation 0.32
Values 3.3 3.2 2.7
[54]
SNU475 SMAD6
Mean 7.65
Standard deviation 0.7
Values 7.2 8.1
[55]
THLE SMAD6
Mean 2.93
Standard deviation 0.37
Values 2.7 3.2
[56]
liver SMAD6
Mean 3.92
Standard deviation 2.9
Values 4.7 7.7 1.7 1.6
[57]
ref_hepatocyte BMPR2
Mean 1.09
Standard deviation 0.28
Values 0.88 1.4 1.2 1.2 0.73
[58]
HepG2 BMPR2
Mean 21.8
Standard deviation 5.9
Values 26 18
[59]
HepG2.C3A BMPR2
Mean 9.92
Standard deviation 0.63
Values 10 9.5
[60]
HuH.7 BMPR2
Mean 15.2
Standard deviation 4.2
Values 11 16 19
[61]
SNU475 BMPR2
Mean 35.1
Standard deviation 7.7
Values 30 41
[62]
THLE BMPR2
Mean 24.7
Standard deviation 0.28
Values 25 25
[63]
liver BMPR2
Mean 30.3
Standard deviation 5.5
Values 33 36 29 24
[64]
ref_hepatocyte RUNX2
Mean 0.0228
Standard deviation 0.051
Values 0 0.11 0 0 0
[65]
HepG2 RUNX2
Mean 0.0279
Standard deviation 0.033
Values 0.0043 0.052
[66]
HepG2.C3A RUNX2
Mean 0.0194
Standard deviation 0.027
Values 0 0.039
[67]
HuH.7 RUNX2
Mean 0.624
Standard deviation 0.22
Values 0.46 0.87 0.54
[68]
SNU475 RUNX2
Mean 5.82
Standard deviation 3.1
Values 8 3.6
[69]
THLE RUNX2
Mean 25.4
Standard deviation 0.45
Values 26 25
[70]
liver RUNX2
Mean 0.398
Standard deviation 0.22
Values 0.4 0.29 0.71 0.21
[71]
ref_hepatocyte BMPR1B
Mean 0.00978
Standard deviation 0.022
Values 0.049 0 0 0 0
[72]
HepG2 BMPR1B
Mean 0.0107
Standard deviation 0.0091
Values 0.0043 0.017
[73]
HepG2.C3A BMPR1B
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[74]
HuH.7 BMPR1B
Mean 0.258
Standard deviation 0.092
Values 0.23 0.36 0.18
[75]
SNU475 BMPR1B
Mean 0.986
Standard deviation 0.082
Values 1 0.93
[76]
THLE BMPR1B
Mean 0.107
Standard deviation 0.051
Values 0.071 0.14
[77]
liver BMPR1B
Mean 1.31
Standard deviation 0.41
Values 0.77 1.4 1.3 1.7
[78]
ref_hepatocyte NOG
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 NOG
Mean 0.0501
Standard deviation 0.059
Values 0.0086 0.092
[80]
HepG2.C3A NOG
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 NOG
Mean 0.00487
Standard deviation 0.0043
Values 0 0.0064 0.0082
[82]
SNU475 NOG
Mean 2.05
Standard deviation 1.7
Values 0.85 3.3
[83]
THLE NOG
Mean 0.0402
Standard deviation 0.027
Values 0.059 0.021
[84]
liver NOG
Mean 0.286
Standard deviation 0.053
Values 0.24 0.24 0.33 0.33