WP_BIOTIN_METABOLISM_INCLUDING_IEMS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PCCB Propionyl-CoA carboxylase beta chain, mitochondrial [1] -0.64[2] -0.86[3] -2.59[4] -0.71[5] -0.28[6] -1.71[7]
2 PC Pyruvate carboxylase, mitochondrial [8] -0.59[9] -0.53[10] 0.21[11] -0.35[12] -2.41[13] 0.55[14]
3 MCCC2 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial [15] 0.81[16] 0.62[17] 0.41[18] 0.14[19] 0.67[20] -0.78[21]
4 PCCA Propionyl-CoA carboxylase alpha chain, mitochondrial [22] -0.89[23] -0.94[24] -1.57[25] -2.22[26] -1.73[27] -0.46[28]
5 MCCC1 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial [29] -0.92[30] -1.03[31] -0.52[32] -1.19[33] -0.45[34] -1.08[35]
6 BTD Biotinidase [36] -0.67[37] -0.51[38] -1.46[39] -1.11[40] -0.11[41] -0.67[42]
7 ACACB Acetyl-CoA carboxylase 2 [43] -0.19[44] 0.64[45] 0.31[46] -0.54[47] 0.16[48] 2.59[49]
8 ACACA Acetyl-CoA carboxylase 1 [50] 3.13[51] 3.33[52] 3.79[53] 3.81[54] 3.40[55] 1.76[56]
9 HLCS Biotin--protein ligase [57] 1.65[58] 1.75[59] 0.74[60] 2.63[61] 2.75[62] 0.83[63]
[1]
ref_hepatocyte PCCB
Mean 41.7
Standard deviation 29
Values 17 79 67 18 27
[2]
HepG2 PCCB
Mean 37
Standard deviation 6.8
Values 42 32
[3]
HepG2.C3A PCCB
Mean 31.3
Standard deviation 3.5
Values 34 29
[4]
HuH.7 PCCB
Mean 12.3
Standard deviation 1.8
Values 13 10 13
[5]
SNU475 PCCB
Mean 20
Standard deviation 5
Values 16 24
[6]
THLE PCCB
Mean 22.8
Standard deviation 3.3
Values 20 25
[7]
liver PCCB
Mean 54.9
Standard deviation 21
Values 34 46 55 84
[8]
ref_hepatocyte PC
Mean 39.5
Standard deviation 46
Values 3.9 93 87 8 5.6
[9]
HepG2 PC
Mean 36.2
Standard deviation 7.4
Values 31 41
[10]
HepG2.C3A PC
Mean 37.2
Standard deviation 8
Values 32 43
[11]
HuH.7 PC
Mean 81.4
Standard deviation 7.4
Values 77 77 90
[12]
SNU475 PC
Mean 24.3
Standard deviation 13
Values 15 33
[13]
THLE PC
Mean 4.93
Standard deviation 0.64
Values 4.5 5.4
[14]
liver PC
Mean 248
Standard deviation 63
Values 2.4e+02 2.7e+02 1.7e+02 3.2e+02
[15]
ref_hepatocyte MCCC2
Mean 24.7
Standard deviation 9.8
Values 11 38 27 22 26
[16]
HepG2 MCCC2
Mean 60.1
Standard deviation 16
Values 71 49
[17]
HepG2.C3A MCCC2
Mean 51.8
Standard deviation 17
Values 64 40
[18]
HuH.7 MCCC2
Mean 58.3
Standard deviation 19
Values 63 37 74
[19]
SNU475 MCCC2
Mean 21.4
Standard deviation 2.4
Values 20 23
[20]
THLE MCCC2
Mean 26.1
Standard deviation 3.3
Values 24 28
[21]
liver MCCC2
Mean 62.1
Standard deviation 26
Values 36 46 72 94
[22]
ref_hepatocyte PCCA
Mean 17.2
Standard deviation 15
Values 3.5 29 37 9.9 6.1
[23]
HepG2 PCCA
Mean 12.9
Standard deviation 1.6
Values 14 12
[24]
HepG2.C3A PCCA
Mean 12.2
Standard deviation 0.74
Values 12 13
[25]
HuH.7 PCCA
Mean 10.3
Standard deviation 0.27
Values 10 11 10
[26]
SNU475 PCCA
Mean 2.91
Standard deviation 0.067
Values 2.9 3
[27]
THLE PCCA
Mean 3.46
Standard deviation 0.45
Values 3.1 3.8
[28]
liver PCCA
Mean 53.8
Standard deviation 7.3
Values 47 58 49 62
[29]
ref_hepatocyte MCCC1
Mean 13.4
Standard deviation 8.4
Values 4.4 22 21 5.1 14
[30]
HepG2 MCCC1
Mean 9.8
Standard deviation 2
Values 11 8.4
[31]
HepG2.C3A MCCC1
Mean 8.89
Standard deviation 0.017
Values 8.9 8.9
[32]
HuH.7 MCCC1
Mean 16.5
Standard deviation 1.3
Values 18 15 16
[33]
SNU475 MCCC1
Mean 4.59
Standard deviation 1.2
Values 3.7 5.4
[34]
THLE MCCC1
Mean 6.51
Standard deviation 0.64
Values 6.1 7
[35]
liver MCCC1
Mean 27.2
Standard deviation 5.9
Values 20 28 27 34
[36]
ref_hepatocyte BTD
Mean 8.84
Standard deviation 10
Values 1.1 24 15 2.1 1.8
[37]
HepG2 BTD
Mean 7.7
Standard deviation 0.5
Values 8.1 7.4
[38]
HepG2.C3A BTD
Mean 8.4
Standard deviation 0.021
Values 8.4 8.4
[39]
HuH.7 BTD
Mean 5.74
Standard deviation 0.4
Values 5.5 6.2 5.5
[40]
SNU475 BTD
Mean 3.22
Standard deviation 0.56
Values 2.8 3.6
[41]
THLE BTD
Mean 5.46
Standard deviation 0.75
Values 4.9 6
[42]
liver BTD
Mean 23.9
Standard deviation 2
Values 21 24 23 26
[43]
ref_hepatocyte ACACB
Mean 5.46
Standard deviation 5.5
Values 1.1 13 9.6 1.7 1.8
[44]
HepG2 ACACB
Mean 6.6
Standard deviation 0.54
Values 7 6.2
[45]
HepG2.C3A ACACB
Mean 11.5
Standard deviation 0.088
Values 12 11
[46]
HuH.7 ACACB
Mean 12.1
Standard deviation 1.9
Values 9.8 13 13
[47]
SNU475 ACACB
Mean 2.94
Standard deviation 0.034
Values 2.9 3
[48]
THLE ACACB
Mean 4.04
Standard deviation 0.24
Values 4.2 3.9
[49]
liver ACACB
Mean 141
Standard deviation 89
Values 2.6e+02 1.6e+02 90 59
[50]
ref_hepatocyte ACACA
Mean 3.02
Standard deviation 0.95
Values 1.7 2.7 3.2 4.3 3.2
[51]
HepG2 ACACA
Mean 36.5
Standard deviation 4.8
Values 40 33
[52]
HepG2.C3A ACACA
Mean 41.2
Standard deviation 13
Values 32 50
[53]
HuH.7 ACACA
Mean 74.7
Standard deviation 16
Values 57 78 89
[54]
SNU475 ACACA
Mean 33.2
Standard deviation 14
Values 23 43
[55]
THLE ACACA
Mean 21.2
Standard deviation 5
Values 18 25
[56]
liver ACACA
Mean 44
Standard deviation 21
Values 50 70 21 35
[57]
ref_hepatocyte HLCS
Mean 2.02
Standard deviation 0.54
Values 1.9 2.9 2 1.6 1.6
[58]
HepG2 HLCS
Mean 8.73
Standard deviation 0.85
Values 9.3 8.1
[59]
HepG2.C3A HLCS
Mean 9.23
Standard deviation 0.52
Values 9.6 8.9
[60]
HuH.7 HLCS
Mean 5.98
Standard deviation 0.68
Values 5.4 5.8 6.7
[61]
SNU475 HLCS
Mean 9.79
Standard deviation 2.9
Values 7.7 12
[62]
THLE HLCS
Mean 9.03
Standard deviation 1.3
Values 8.1 9.9
[63]
liver HLCS
Mean 15.4
Standard deviation 3.7
Values 14 20 12 16