WP_BIOGENIC_AMINE_SYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PAH Phenylalanine-4-hydroxylase [1] -0.48[2] -0.17[3] -0.21[4] -6.37[5] -8.05[6] -0.08[7]
2 COMT Catechol O-methyltransferase [8] 1.19[9] 0.78[10] -1.35[11] 2.25[12] 0.58[13] -0.30[14]
3 MAOA Amine oxidase [flavin-containing] A [15] -1.38[16] -1.60[17] 0.70[18] -0.66[19] 2.80[20] 0.84[21]
4 DDC Aromatic-L-amino-acid decarboxylase [22] -0.26[23] -0.06[24] 1.37[25] -3.21[26] -5.98[27] -0.50[28]
5 ACHE Acetylcholinesterase [29] -0.27[30] -3.59[31] -0.54[32] -1.17[33] -2.27[34] -5.11[35]
6 ASMT Acetylserotonin O-methyltransferase [36] [37] [38] [39] [40] [41] [42]
7 DBH Dopamine beta-hydroxylase [43] 2.15[44] 3.20[45] 2.02[46] -2.50[47] 0.00[48] 4.34[49]
8 HDC Histidine decarboxylase [50] -3.56[51] -4.15[52] -3.96[53] 1.33[54] [55] 0.89[56]
9 GAD1 Glutamate decarboxylase 1 [57] 2.64[58] 1.95[59] 5.34[60] 2.72[61] 2.17[62] -4.46[63]
10 TH Tyrosine 3-monooxygenase [64] 3.19[65] [66] [67] [68] -1.69[69] 0.89[70]
11 AANAT Serotonin N-acetyltransferase [71] 1.17[72] 2.71[73] 2.78[74] 5.36[75] 3.13[76] 0.47[77]
12 GAD2 Glutamate decarboxylase 2 [78] [79] [80] [81] [82] [83] [84]
13 CHAT Choline O-acetyltransferase [85] [86] [87] [88] 5.94[89] [90] [91]
14 PNMT Phenylethanolamine N-methyltransferase [92] [93] [94] [95] [96] [97] [98]
15 MIR4761 [99] [100] [101] [102] [103] [104] [105]
16 TPH1 Tryptophan 5-hydroxylase 1 [106] [107] [108] [109] [110] [111] [112]
[1]
ref_hepatocyte PAH
Mean 136
Standard deviation 1.9e+02
Values 6.3 4.6e+02 1.6e+02 42 11
[2]
HepG2 PAH
Mean 61
Standard deviation 30
Values 82 40
[3]
HepG2.C3A PAH
Mean 135
Standard deviation 6.2
Values 1.4e+02 1.3e+02
[4]
HuH.7 PAH
Mean 123
Standard deviation 14
Values 1.4e+02 1.1e+02 1.2e+02
[5]
SNU475 PAH
Mean 0.19
Standard deviation 0.12
Values 0.28 0.1
[6]
THLE PAH
Mean 0.219
Standard deviation 0.17
Values 0.34 0.096
[7]
liver PAH
Mean 289
Standard deviation 1.2e+02
Values 1.5e+02 2.7e+02 4.3e+02 3.1e+02
[8]
ref_hepatocyte COMT
Mean 41.6
Standard deviation 29
Values 14 83 61 24 25
[9]
HepG2 COMT
Mean 59.3
Standard deviation 6.8
Values 55 64
[10]
HepG2.C3A COMT
Mean 80
Standard deviation 0.37
Values 80 80
[11]
HuH.7 COMT
Mean 17.1
Standard deviation 2.6
Values 19 18 14
[12]
SNU475 COMT
Mean 22.9
Standard deviation 4.5
Values 20 26
[13]
THLE COMT
Mean 26.6
Standard deviation 0.81
Values 26 27
[14]
liver COMT
Mean 76.3
Standard deviation 82
Values 20 20 1.9e+02 71
[15]
ref_hepatocyte MAOA
Mean 22.1
Standard deviation 16
Values 8.6 41 34 3.4 23
[16]
HepG2 MAOA
Mean 5.32
Standard deviation 0.22
Values 5.2 5.5
[17]
HepG2.C3A MAOA
Mean 8.16
Standard deviation 2.3
Values 6.5 9.8
[18]
HuH.7 MAOA
Mean 37.5
Standard deviation 10
Values 28 49 36
[19]
SNU475 MAOA
Mean 1.62
Standard deviation 0.75
Values 2.1 1.1
[20]
THLE MAOA
Mean 66.1
Standard deviation 1.4
Values 67 65
[21]
liver MAOA
Mean 88.9
Standard deviation 19
Values 65 90 1.1e+02 88
[22]
ref_hepatocyte DDC
Mean 16.2
Standard deviation 7.9
Values 3.1 24 19 20 15
[23]
HepG2 DDC
Mean 8.45
Standard deviation 3.2
Values 11 6.2
[24]
HepG2.C3A DDC
Mean 17.3
Standard deviation 4.6
Values 21 14
[25]
HuH.7 DDC
Mean 43.9
Standard deviation 9.4
Values 53 34 45
[26]
SNU475 DDC
Mean 0.201
Standard deviation 0.063
Values 0.16 0.25
[27]
THLE DDC
Mean 0.11
Standard deviation 0.087
Values 0.17 0.048
[28]
liver DDC
Mean 25.7
Standard deviation 11
Values 28 15 41 19
[29]
ref_hepatocyte ACHE
Mean 1.58
Standard deviation 1.8
Values 4.5 0.4 0.71 0.21 2.1
[30]
HepG2 ACHE
Mean 0.818
Standard deviation 0.67
Values 0.35 1.3
[31]
HepG2.C3A ACHE
Mean 0.146
Standard deviation 0.055
Values 0.11 0.18
[32]
HuH.7 ACHE
Mean 1.14
Standard deviation 0.67
Values 0.76 1.9 0.74
[33]
SNU475 ACHE
Mean 0.0812
Standard deviation 0.036
Values 0.056 0.11
[34]
THLE ACHE
Mean 0.14
Standard deviation 0.065
Values 0.095 0.19
[35]
liver ACHE
Mean 0.102
Standard deviation 0.031
Values 0.066 0.1 0.14 0.1
[36]
ref_hepatocyte ASMT
Mean 0.657
Standard deviation 0.74
Values 0 0.88 1.8 0.29 0.27
[37]
HepG2 ASMT
Missing
[38]
HepG2.C3A ASMT
Missing
[39]
HuH.7 ASMT
Missing
[40]
SNU475 ASMT
Missing
[41]
THLE ASMT
Missing
[42]
liver ASMT
Missing
[43]
ref_hepatocyte DBH
Mean 0.238
Standard deviation 0.38
Values 0 0.88 0.31 0 0
[44]
HepG2 DBH
Mean 0.659
Standard deviation 0.37
Values 0.92 0.4
[45]
HepG2.C3A DBH
Mean 2.44
Standard deviation 0.22
Values 2.3 2.6
[46]
HuH.7 DBH
Mean 1.01
Standard deviation 0.5
Values 0.53 1.5 0.98
[47]
SNU475 DBH
Mean 0.00485
Standard deviation 0.0003
Values 0.0051 0.0046
[48]
THLE DBH
Mean 0.102
Standard deviation 0.031
Values 0.12 0.08
[49]
liver DBH
Mean 10.8
Standard deviation 6.3
Values 12 7.6 4.7 19
[50]
ref_hepatocyte HDC
Mean 0.162
Standard deviation 0.24
Values 0 0.28 0.53 0 0
[51]
HepG2 HDC
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[52]
HepG2.C3A HDC
Mean 0.0102
Standard deviation 0.00071
Values 0.011 0.0097
[53]
HuH.7 HDC
Mean 0.0109
Standard deviation 0.019
Values 0 0 0.033
[54]
SNU475 HDC
Mean 0.0473
Standard deviation 0.041
Values 0.076 0.019
[55]
THLE HDC
Mean 0
Standard deviation 0
Values 0 0
[56]
liver HDC
Mean 0.675
Standard deviation 0.64
Values 0.46 0.6 0.071 1.6
[57]
ref_hepatocyte GAD1
Mean 0.132
Standard deviation 0.29
Values 0 0 0 0 0.66
[58]
HepG2 GAD1
Mean 0.511
Standard deviation 0.23
Values 0.35 0.67
[59]
HepG2.C3A GAD1
Mean 0.567
Standard deviation 0.17
Values 0.69 0.45
[60]
HuH.7 GAD1
Mean 5.59
Standard deviation 0.85
Values 5.4 6.5 4.9
[61]
SNU475 GAD1
Mean 0.101
Standard deviation 0.044
Values 0.13 0.07
[62]
THLE GAD1
Mean 0.253
Standard deviation 0.1
Values 0.33 0.18
[63]
liver GAD1
Mean 0.0135
Standard deviation 0.019
Values 0.04 0.014 0 0
[64]
ref_hepatocyte TH
Mean 0.0869
Standard deviation 0.15
Values 0.35 0.089 0 0 0
[65]
HepG2 TH
Mean 0.495
Standard deviation 0.24
Values 0.33 0.66
[66]
HepG2.C3A TH
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 TH
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 TH
Mean 0
Standard deviation 0
Values 0 0
[69]
THLE TH
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[70]
liver TH
Mean 0.362
Standard deviation 0.4
Values 0.95 0.23 0.16 0.1
[71]
ref_hepatocyte AANAT
Mean 0.00813
Standard deviation 0.018
Values 0 0.041 0 0 0
[72]
HepG2 AANAT
Mean 0.0115
Standard deviation 0.016
Values 0 0.023
[73]
HepG2.C3A AANAT
Mean 0.0593
Standard deviation 0.054
Values 0.021 0.097
[74]
HuH.7 AANAT
Mean 0.0585
Standard deviation 0.03
Values 0.084 0.026 0.066
[75]
SNU475 AANAT
Mean 0.0386
Standard deviation 0.0044
Values 0.035 0.042
[76]
THLE AANAT
Mean 0.0305
Standard deviation 0.0096
Values 0.024 0.037
[77]
liver AANAT
Mean 0.0253
Standard deviation 0.021
Values 0.026 0 0.024 0.051
[78]
ref_hepatocyte GAD2
Mean 0.0065
Standard deviation 0.015
Values 0 0.033 0 0 0
[79]
HepG2 GAD2
Missing
[80]
HepG2.C3A GAD2
Missing
[81]
HuH.7 GAD2
Missing
[82]
SNU475 GAD2
Missing
[83]
THLE GAD2
Missing
[84]
liver GAD2
Missing
[85]
ref_hepatocyte CHAT
Mean 0.0065
Standard deviation 0.015
Values 0 0.033 0 0 0
[86]
HepG2 CHAT
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A CHAT
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 CHAT
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 CHAT
Mean 0.0464
Standard deviation 0.066
Values 0 0.093
[90]
THLE CHAT
Mean 0
Standard deviation 0
Values 0 0
[91]
liver CHAT
Mean 0
Standard deviation 0
Values 0 0 0 0
[92]
ref_hepatocyte PNMT
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 PNMT
Mean 0.115
Standard deviation 0.096
Values 0.047 0.18
[94]
HepG2.C3A PNMT
Mean 0.0107
Standard deviation 0.015
Values 0.021 0
[95]
HuH.7 PNMT
Mean 0.00975
Standard deviation 0.0086
Values 0 0.013 0.016
[96]
SNU475 PNMT
Mean 0.0652
Standard deviation 0.0062
Values 0.061 0.07
[97]
THLE PNMT
Mean 0.089
Standard deviation 0.058
Values 0.13 0.048
[98]
liver PNMT
Mean 0.0565
Standard deviation 0.034
Values 0.026 0.029 0.094 0.077
[99]
ref_hepatocyte MIR4761
Missing
[100]
HepG2 MIR4761
Missing
[101]
HepG2.C3A MIR4761
Missing
[102]
HuH.7 MIR4761
Missing
[103]
SNU475 MIR4761
Missing
[104]
THLE MIR4761
Missing
[105]
liver MIR4761
Missing
[106]
ref_hepatocyte TPH1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[107]
HepG2 TPH1
Mean 0.0701
Standard deviation 0.01
Values 0.077 0.063
[108]
HepG2.C3A TPH1
Mean 0.269
Standard deviation 0.11
Values 0.34 0.19
[109]
HuH.7 TPH1
Mean 0.0367
Standard deviation 0.025
Values 0.019 0.026 0.066
[110]
SNU475 TPH1
Mean 0.0361
Standard deviation 0.008
Values 0.03 0.042
[111]
THLE TPH1
Mean 0.0911
Standard deviation 0.039
Values 0.12 0.064
[112]
liver TPH1
Mean 0.0508
Standard deviation 0.037
Values 0.066 0.086 0 0.051