WP_AUTOPHAGY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | BECN1 | Beclin-1 | [1] | -1.16[2] | -1.76[3] | -1.91[4] | -1.66[5] | -1.81[6] | -1.70[7] |
2 | ATG3 | Ubiquitin-like-conjugating enzyme ATG3 | [8] | -2.65[9] | -2.50[10] | -2.05[11] | -1.95[12] | -1.39[13] | -1.80[14] |
3 | MAP1LC3 | Microtubule-associated proteins 1A/1B light chain 3B | [15] | 0.40[16] | -0.26[17] | -1.59[18] | -0.16[19] | 0.33[20] | -1.20[21] |
4 | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 | [22] | -1.74[23] | -1.59[24] | -1.57[25] | -0.66[26] | -1.07[27] | -2.29[28] |
5 | AKT1S1 | Proline-rich AKT1 substrate 1 | [29] | -0.79[30] | -1.32[31] | -1.07[32] | -1.06[33] | -0.57[34] | -1.83[35] |
6 | PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2 | [36] | -4.38[37] | -9.86[38] | -3.53[39] | -2.05[40] | -2.04[41] | -1.12[42] |
7 | ATG16L1 | Autophagy-related protein 16-1 | [43] | -0.28[44] | -0.63[45] | -1.45[46] | -0.65[47] | -1.27[48] | -1.26[49] |
8 | MLST8 | Target of rapamycin complex subunit LST8 | [50] | -0.50[51] | -0.55[52] | -0.28[53] | -1.29[54] | -1.06[55] | -1.21[56] |
9 | WIPI2 | WD repeat domain phosphoinositide-interacting protein 2 | [57] | 0.31[58] | 0.05[59] | 0.06[60] | -0.22[61] | 0.54[62] | 0.18[63] |
10 | PRKAA1 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | [64] | -0.41[65] | 0.49[66] | 1.91[67] | 1.15[68] | 1.30[69] | 1.42[70] |
11 | PRKAB2 | 5'-AMP-activated protein kinase subunit beta-2 | [71] | 0.56[72] | 1.36[73] | 1.38[74] | 0.71[75] | -0.44[76] | 0.77[77] |
12 | ATG9A | Autophagy-related protein 9A | [78] | 1.36[79] | 0.91[80] | 0.28[81] | 1.06[82] | 1.06[83] | 0.98[84] |
13 | ATG5 | Autophagy protein 5 | [85] | -0.54[86] | 0.10[87] | -0.34[88] | 0.47[89] | 0.09[90] | 0.20[91] |
14 | ATG13 | Autophagy-related protein 13 | [92] | 1.72[93] | 1.30[94] | 1.44[95] | -0.18[96] | 0.79[97] | 1.20[98] |
15 | PRKAB1 | 5'-AMP-activated protein kinase subunit beta-1 | [99] | 0.39[100] | 0.54[101] | -0.41[102] | -0.38[103] | -0.39[104] | -0.64[105] |
16 | ATG12 | Ubiquitin-like protein ATG12 | [106] | 0.11[107] | 0.62[108] | 0.45[109] | 1.15[110] | 0.80[111] | 0.79[112] |
17 | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | [113] | 0.06[114] | 0.30[115] | -0.71[116] | 0.49[117] | 0.58[118] | -0.01[119] |
18 | MTOR | Serine/threonine-protein kinase mTOR | [120] | 2.21[121] | 2.84[122] | 2.31[123] | 2.37[124] | 2.33[125] | 2.81[126] |
19 | RB1CC1 | RB1-inducible coiled-coil protein 1 | [127] | -0.04[128] | 2.38[129] | 1.28[130] | 2.02[131] | 1.42[132] | 2.22[133] |
20 | ULK1 | Serine/threonine-protein kinase ULK1 | [134] | 0.99[135] | 0.88[136] | 1.99[137] | 1.66[138] | 0.89[139] | 1.25[140] |
21 | DEPTOR | DEP domain-containing mTOR-interacting protein | [141] | -3.64[142] | -2.84[143] | 1.11[144] | -4.56[145] | -2.04[146] | 0.21[147] |
22 | ATG14 | Beclin 1-associated autophagy-related key regulator | [148] | 0.40[149] | 0.57[150] | 0.59[151] | 1.15[152] | 0.79[153] | 0.10[154] |
23 | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7 | [155] | 0.67[156] | -0.20[157] | 0.43[158] | 0.37[159] | 1.10[160] | 1.12[161] |
24 | RPTOR | Regulatory-associated protein of mTOR | [162] | 2.76[163] | 1.61[164] | 1.62[165] | 1.54[166] | 1.65[167] | 1.69[168] |
25 | PIK3R4 | Phosphoinositide 3-kinase regulatory subunit 4 | [169] | 0.84[170] | 0.52[171] | 1.39[172] | 1.35[173] | 1.70[174] | 2.23[175] |
26 | AMBRA1 | Activating molecule in BECN1-regulated autophagy protein 1 | [176] | 2.10[177] | 1.30[178] | 2.13[179] | 0.03[180] | 0.78[181] | 1.17[182] |
27 | UVRAG | UV radiation resistance-associated gene protein | [183] | 1.19[184] | 0.95[185] | 0.25[186] | 0.95[187] | 1.38[188] | 1.35[189] |
28 | PRKAA2 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | [190] | 2.71[191] | 2.77[192] | 2.70[193] | 2.73[194] | 0.65[195] | 1.21[196] |
29 | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3 | [197] | -2.06[198] | [199] | -2.87[200] | -1.33[201] | [202] | 2.48[203] |
30 | ATG101 | Autophagy-related protein 101 | [204] | [205] | [206] | [207] | [208] | [209] | [210] |