WP_ATR_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RPA1 Replication protein A 70 kDa DNA-binding subunit [1] 0.31[2] -0.30[3] -0.35[4] 0.04[5] -0.04[6] -0.96[7]
2 TOPBP1 DNA topoisomerase 2-binding protein 1 [8] 0.02[9] 0.70[10] 0.53[11] 0.32[12] 0.62[13] -0.08[14]
3 HUS1 Checkpoint protein HUS1 [15] -1.72[16] -1.79[17] -1.58[18] -1.92[19] -2.22[20] 0.41[21]
4 CHEK1 Serine/threonine-protein kinase Chk1 [22] 0.53[23] 0.55[24] -0.21[25] 0.34[26] 0.47[27] -2.99[28]
5 RAD1 Cell cycle checkpoint protein RAD1 [29] 0.36[30] 0.69[31] 0.90[32] 0.00[33] 0.78[34] -0.06[35]
6 RAD9A Cell cycle checkpoint control protein RAD9A [36] -0.93[37] -1.00[38] 0.49[39] 0.52[40] -1.76[41] -1.14[42]
7 ATRIP ATR-interacting protein [43] -0.76[44] -0.86[45] -0.31[46] -2.15[47] -1.18[48] -1.13[49]
8 ATR Serine/threonine-protein kinase ATR [50] 0.09[51] 0.74[52] 0.50[53] 0.72[54] 0.58[55] 2.58[56]
9 RAD9B Cell cycle checkpoint control protein RAD9B [57] -4.33[58] -1.48[59] -2.50[60] -1.38[61] -2.14[62] -1.75[63]
[1]
ref_hepatocyte RPA1
Mean 8.25
Standard deviation 3.9
Values 5.5 6.7 5.3 9.2 15
[2]
HepG2 RPA1
Mean 45.3
Standard deviation 8.3
Values 51 39
[3]
HepG2.C3A RPA1
Mean 33.6
Standard deviation 11
Values 41 26
[4]
HuH.7 RPA1
Mean 39
Standard deviation 14
Values 48 23 47
[5]
SNU475 RPA1
Mean 54.6
Standard deviation 1
Values 54 55
[6]
THLE RPA1
Mean 62.1
Standard deviation 11
Values 54 70
[7]
liver RPA1
Mean 11.7
Standard deviation 1.8
Values 9.5 12 12 14
[8]
ref_hepatocyte TOPBP1
Mean 3.37
Standard deviation 2.5
Values 2.5 1.1 1.1 5.6 6.5
[9]
HepG2 TOPBP1
Mean 15.1
Standard deviation 7.9
Values 21 9.6
[10]
HepG2.C3A TOPBP1
Mean 27.6
Standard deviation 14
Values 37 18
[11]
HuH.7 TOPBP1
Mean 29.5
Standard deviation 9.5
Values 33 19 37
[12]
SNU475 TOPBP1
Mean 27.1
Standard deviation 3.9
Values 30 24
[13]
THLE TOPBP1
Mean 40.2
Standard deviation 1.7
Values 41 39
[14]
liver TOPBP1
Mean 8.82
Standard deviation 4
Values 9.8 14 5.3 6.1
[15]
ref_hepatocyte HUS1
Mean 3.03
Standard deviation 1.3
Values 2 4.3 4 1.3 3.5
[16]
HepG2 HUS1
Mean 4.07
Standard deviation 1.2
Values 4.9 3.2
[17]
HepG2.C3A HUS1
Mean 4.39
Standard deviation 0.9
Values 5 3.8
[18]
HuH.7 HUS1
Mean 6.13
Standard deviation 0.51
Values 5.6 6.3 6.5
[19]
SNU475 HUS1
Mean 5.15
Standard deviation 0.24
Values 5.3 5
[20]
THLE HUS1
Mean 5.04
Standard deviation 0.88
Values 4.4 5.7
[21]
liver HUS1
Mean 11.1
Standard deviation 2.6
Values 13 8.2 13 9.7
[22]
ref_hepatocyte CHEK1
Mean 2.44
Standard deviation 1.9
Values 1.9 0.99 0.69 3.2 5.4
[23]
HepG2 CHEK1
Mean 15.6
Standard deviation 7.2
Values 21 11
[24]
HepG2.C3A CHEK1
Mean 17.9
Standard deviation 12
Values 26 9.6
[25]
HuH.7 CHEK1
Mean 12.7
Standard deviation 5.1
Values 16 6.8 15
[26]
SNU475 CHEK1
Mean 19.9
Standard deviation 4.6
Values 23 17
[27]
THLE CHEK1
Mean 26.2
Standard deviation 4.4
Values 23 29
[28]
liver CHEK1
Mean 0.851
Standard deviation 0.2
Values 0.64 1 0.73 1
[29]
ref_hepatocyte RAD1
Mean 1.96
Standard deviation 0.26
Values 2.2 1.5 1.9 2.2 2
[30]
HepG2 RAD1
Mean 11.2
Standard deviation 2.3
Values 13 9.5
[31]
HepG2.C3A RAD1
Mean 15.9
Standard deviation 6.5
Values 20 11
[32]
HuH.7 RAD1
Mean 22.1
Standard deviation 5.4
Values 23 16 27
[33]
SNU475 RAD1
Mean 12.6
Standard deviation 1.7
Values 14 11
[34]
THLE RAD1
Mean 26.1
Standard deviation 1.3
Values 27 25
[35]
liver RAD1
Mean 5.22
Standard deviation 0.96
Values 5 4.2 5.2 6.5
[36]
ref_hepatocyte RAD9A
Mean 1.87
Standard deviation 0.75
Values 0.94 1.9 3 2 1.5
[37]
HepG2 RAD9A
Mean 4.33
Standard deviation 0.024
Values 4.3 4.3
[38]
HepG2.C3A RAD9A
Mean 4.7
Standard deviation 0.12
Values 4.8 4.6
[39]
HuH.7 RAD9A
Mean 15.8
Standard deviation 6.3
Values 22 9.4 16
[40]
SNU475 RAD9A
Mean 17.3
Standard deviation 3.3
Values 20 15
[41]
THLE RAD9A
Mean 4.29
Standard deviation 0.62
Values 4.7 3.8
[42]
liver RAD9A
Mean 2.36
Standard deviation 1.1
Values 1.8 1.1 3.3 3.2
[43]
ref_hepatocyte ATRIP
Mean 1.54
Standard deviation 0.36
Values 2 1.1 1.4 1.6 1.6
[44]
HepG2 ATRIP
Mean 4.04
Standard deviation 0.45
Values 4.4 3.7
[45]
HepG2.C3A ATRIP
Mean 4.26
Standard deviation 1.1
Values 5.1 3.5
[46]
HuH.7 ATRIP
Mean 7.5
Standard deviation 2.3
Values 9.2 4.8 8.5
[47]
SNU475 ATRIP
Mean 2.23
Standard deviation 0.45
Values 2.5 1.9
[48]
THLE ATRIP
Mean 5.29
Standard deviation 1.3
Values 4.4 6.2
[49]
liver ATRIP
Mean 1.96
Standard deviation 0.19
Values 2.2 2.1 1.9 1.7
[50]
ref_hepatocyte ATR
Mean 1.48
Standard deviation 0.93
Values 0.87 0.82 1.1 1.5 3.1
[51]
HepG2 ATR
Mean 6.99
Standard deviation 2.6
Values 8.9 5.1
[52]
HepG2.C3A ATR
Mean 12.4
Standard deviation 3
Values 15 10
[53]
HuH.7 ATR
Mean 12.6
Standard deviation 3.2
Values 11 10 16
[54]
SNU475 ATR
Mean 15.7
Standard deviation 0.082
Values 16 16
[55]
THLE ATR
Mean 17.2
Standard deviation 1.5
Values 18 16
[56]
liver ATR
Mean 24.7
Standard deviation 14
Values 28 43 13 15
[57]
ref_hepatocyte RAD9B
Mean 0.157
Standard deviation 0.11
Values 0.082 0.041 0.22 0.31 0.12
[58]
HepG2 RAD9B
Mean 0.0344
Standard deviation 4.6e-05
Values 0.034 0.034
[59]
HepG2.C3A RAD9B
Mean 0.282
Standard deviation 0.11
Values 0.2 0.36
[60]
HuH.7 RAD9B
Mean 0.167
Standard deviation 0.048
Values 0.11 0.19 0.2
[61]
SNU475 RAD9B
Mean 0.388
Standard deviation 0.14
Values 0.29 0.49
[62]
THLE RAD9B
Mean 0.275
Standard deviation 0.013
Values 0.28 0.27
[63]
liver RAD9B
Mean 0.129
Standard deviation 0.052
Values 0.16 0.19 0.094 0.077