WP_APOPTOSIS_MODULATION_BY_HSP70 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HSPA1A Heat shock 70 kDa protein 1A [1] -4.14[2] -3.88[3] -4.91[4] -3.76[5] -5.04[6] -4.44[7]
2 AIFM1 Apoptosis-inducing factor 1, mitochondrial [8] 0.26[9] -0.14[10] 1.06[11] -0.42[12] -0.61[13] 1.15[14]
3 TNFRSF1A Tumor necrosis factor receptor superfamily member 1A [15] 0.97[16] 0.44[17] 0.81[18] 1.53[19] 1.88[20] 1.39[21]
4 CYCS Cytochrome c [22] 2.77[23] 2.90[24] 3.05[25] 2.50[26] 3.07[27] 2.63[28]
5 CASP3 Caspase-3 [29] 1.57[30] 2.18[31] -0.29[32] 0.27[33] 1.43[34] 0.51[35]
6 BID BH3-interacting domain death agonist [36] 1.17[37] 1.20[38] 0.90[39] 0.88[40] 0.51[41] 1.49[42]
7 FAS Tumor necrosis factor receptor superfamily member 6 [43] -0.16[44] 0.55[45] -7.38[46] -0.58[47] 0.11[48] -0.41[49]
8 CASP7 Caspase-7 [50] 1.13[51] 0.69[52] 1.21[53] 0.27[54] 0.64[55] 0.83[56]
9 FADD FAS-associated death domain protein [57] 1.48[58] 0.70[59] 1.50[60] 3.10[61] 1.08[62] -0.46[63]
10 CASP8 Caspase-8 [64] 1.46[65] 1.96[66] 1.21[67] 1.08[68] 0.51[69] -0.11[70]
11 CASP6 Caspase-6 [71] 0.17[72] 0.31[73] 0.75[74] 0.21[75] 0.06[76] 0.43[77]
12 NFKB1 Nuclear factor NF-kappa-B p105 subunit [78] 2.11[79] 1.72[80] 1.58[81] 0.92[82] 2.00[83] 1.76[84]
13 RIPK1 Receptor-interacting serine/threonine-protein kinase 1 [85] 1.73[86] 1.82[87] 1.58[88] 2.24[89] 1.94[90] 2.80[91]
14 CASP9 Caspase-9 [92] 1.59[93] 2.48[94] 1.68[95] 1.41[96] 0.90[97] 0.78[98]
15 CASP2 Caspase-2 [99] 3.14[100] 2.70[101] 3.58[102] 3.04[103] 3.64[104] 2.90[105]
16 APAF1 Apoptotic protease-activating factor 1 [106] 3.10[107] 3.45[108] 3.78[109] 3.79[110] 3.06[111] 2.80[112]
17 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 [113] 4.09[114] 3.73[115] 3.54[116] 3.49[117] 2.54[118] 4.11[119]
18 FASLG Tumor necrosis factor ligand superfamily member 6 [120] -2.37[121] -0.57[122] -4.47[123] [124] [125] 1.90[126]
19 MAPK10 Mitogen-activated protein kinase 10 [127] -0.05[128] [129] [130] 10.07[131] 5.98[132] 8.56[133]
[1]
ref_hepatocyte HSPA1A
Mean 298
Standard deviation 3.4e+02
Values 8.8e+02 2.5e+02 2.5e+02 54 62
[2]
HepG2 HSPA1A
Mean 13.7
Standard deviation 1.6
Values 13 15
[3]
HepG2.C3A HSPA1A
Mean 15.4
Standard deviation 6.8
Values 11 20
[4]
HuH.7 HSPA1A
Mean 6.88
Standard deviation 5.3
Values 3.7 13 4
[5]
SNU475 HSPA1A
Mean 18
Standard deviation 1.8
Values 19 17
[6]
THLE HSPA1A
Mean 7.41
Standard deviation 0.57
Values 7 7.8
[7]
liver HSPA1A
Mean 7.87
Standard deviation 3.2
Values 5.8 4.7 9.7 11
[8]
ref_hepatocyte AIFM1
Mean 38.8
Standard deviation 20
Values 11 58 57 42 26
[9]
HepG2 AIFM1
Mean 37.9
Standard deviation 11
Values 46 30
[10]
HepG2.C3A AIFM1
Mean 26.8
Standard deviation 3.1
Values 29 25
[11]
HuH.7 AIFM1
Mean 56.2
Standard deviation 19
Values 71 35 63
[12]
SNU475 AIFM1
Mean 23.8
Standard deviation 2.3
Values 22 25
[13]
THLE AIFM1
Mean 20.8
Standard deviation 3.6
Values 18 23
[14]
liver AIFM1
Mean 49.2
Standard deviation 27
Values 24 29 65 79
[15]
ref_hepatocyte TNFRSF1A
Mean 30.7
Standard deviation 20
Values 24 48 55 11 15
[16]
HepG2 TNFRSF1A
Mean 49
Standard deviation 6
Values 45 53
[17]
HepG2.C3A TNFRSF1A
Mean 31.7
Standard deviation 8.2
Values 26 37
[18]
HuH.7 TNFRSF1A
Mean 37.3
Standard deviation 0.38
Values 37 37 38
[19]
SNU475 TNFRSF1A
Mean 72.7
Standard deviation 0.99
Values 72 73
[20]
THLE TNFRSF1A
Mean 92.5
Standard deviation 20
Values 78 1.1e+02
[21]
liver TNFRSF1A
Mean 46.1
Standard deviation 22
Values 33 26 51 74
[22]
ref_hepatocyte CYCS
Mean 14.3
Standard deviation 4.3
Values 7.5 14 15 16 19
[23]
HepG2 CYCS
Mean 79.8
Standard deviation 18
Values 93 67
[24]
HepG2.C3A CYCS
Mean 81.4
Standard deviation 39
Values 1.1e+02 54
[25]
HuH.7 CYCS
Mean 82.3
Standard deviation 19
Values 94 60 93
[26]
SNU475 CYCS
Mean 66.3
Standard deviation 0.99
Values 67 66
[27]
THLE CYCS
Mean 98.4
Standard deviation 7.6
Values 93 1e+02
[28]
liver CYCS
Mean 50.8
Standard deviation 34
Values 19 30 59 95
[29]
ref_hepatocyte CASP3
Mean 12.5
Standard deviation 12
Values 6.8 5.1 4.9 33 13
[30]
HepG2 CASP3
Mean 30.3
Standard deviation 8.2
Values 36 25
[31]
HepG2.C3A CASP3
Mean 43.1
Standard deviation 22
Values 59 27
[32]
HuH.7 CASP3
Mean 7.08
Standard deviation 1
Values 7.8 7.5 5.9
[33]
SNU475 CASP3
Mean 12.3
Standard deviation 0.36
Values 12 13
[34]
THLE CASP3
Mean 27.6
Standard deviation 0.68
Values 27 28
[35]
liver CASP3
Mean 10.2
Standard deviation 4.2
Values 6.1 9 9.5 16
[36]
ref_hepatocyte BID
Mean 12.3
Standard deviation 4.8
Values 17 12 15 4.5 12
[37]
HepG2 BID
Mean 22.5
Standard deviation 0.74
Values 23 22
[38]
HepG2.C3A BID
Mean 21.5
Standard deviation 4.7
Values 25 18
[39]
HuH.7 BID
Mean 15.9
Standard deviation 4.6
Values 21 12 15
[40]
SNU475 BID
Mean 18.5
Standard deviation 1.4
Values 17 19
[41]
THLE BID
Mean 14.3
Standard deviation 1.7
Values 13 15
[42]
liver BID
Mean 19.7
Standard deviation 11
Values 10 9.4 30 29
[43]
ref_hepatocyte FAS
Mean 10.9
Standard deviation 10
Values 13 3.1 5 5.6 28
[44]
HepG2 FAS
Mean 7.93
Standard deviation 5
Values 11 4.4
[45]
HepG2.C3A FAS
Mean 12.1
Standard deviation 8.5
Values 18 6.1
[46]
HuH.7 FAS
Mean 0.0451
Standard deviation 0.028
Values 0.075 0.019 0.041
[47]
SNU475 FAS
Mean 5.96
Standard deviation 1.8
Values 7.2 4.7
[48]
THLE FAS
Mean 9.58
Standard deviation 1.5
Values 11 8.5
[49]
liver FAS
Mean 4.68
Standard deviation 1.2
Values 3.7 4.1 6.4 4.5
[50]
ref_hepatocyte CASP7
Mean 10
Standard deviation 4.1
Values 15 6 7.6 7.8 14
[51]
HepG2 CASP7
Mean 17.9
Standard deviation 4
Values 21 15
[52]
HepG2.C3A CASP7
Mean 12.4
Standard deviation 4
Values 15 9.5
[53]
HuH.7 CASP7
Mean 16.1
Standard deviation 1.8
Values 18 15 15
[54]
SNU475 CASP7
Mean 9.89
Standard deviation 0.26
Values 9.7 10
[55]
THLE CASP7
Mean 12.8
Standard deviation 0.29
Values 13 13
[56]
liver CASP7
Mean 10.2
Standard deviation 3.1
Values 10 6.6 14 9.7
[57]
ref_hepatocyte FADD
Mean 9.28
Standard deviation 6.6
Values 20 5.1 6.3 3.8 12
[58]
HepG2 FADD
Mean 21.1
Standard deviation 4.6
Values 18 24
[59]
HepG2.C3A FADD
Mean 11.5
Standard deviation 1.6
Values 13 10
[60]
HuH.7 FADD
Mean 18.2
Standard deviation 3.2
Values 22 16 16
[61]
SNU475 FADD
Mean 65.1
Standard deviation 11
Values 58 73
[62]
THLE FADD
Mean 16
Standard deviation 3.5
Values 14 19
[63]
liver FADD
Mean 3.86
Standard deviation 1.3
Values 5.1 4.9 2.5 3
[64]
ref_hepatocyte CASP8
Mean 8.88
Standard deviation 6.8
Values 8.9 2.8 1.9 18 13
[65]
HepG2 CASP8
Mean 19.9
Standard deviation 3.1
Values 18 22
[66]
HepG2.C3A CASP8
Mean 26.3
Standard deviation 13
Values 35 17
[67]
HuH.7 CASP8
Mean 14.2
Standard deviation 3.6
Values 18 11 14
[68]
SNU475 CASP8
Mean 15.4
Standard deviation 0.7
Values 15 16
[69]
THLE CASP8
Mean 10.3
Standard deviation 0.97
Values 9.6 11
[70]
liver CASP8
Mean 4.72
Standard deviation 0.87
Values 5 5.2 3.4 5.3
[71]
ref_hepatocyte CASP6
Mean 8.44
Standard deviation 1.3
Values 7.9 8.2 7 8.6 10
[72]
HepG2 CASP6
Mean 7.74
Standard deviation 2.2
Values 9.3 6.2
[73]
HepG2.C3A CASP6
Mean 7.97
Standard deviation 4.4
Values 11 4.9
[74]
HuH.7 CASP6
Mean 9.83
Standard deviation 3.2
Values 13 6.4 10
[75]
SNU475 CASP6
Mean 8.02
Standard deviation 2.2
Values 6.5 9.5
[76]
THLE CASP6
Mean 7.17
Standard deviation 0.61
Values 6.7 7.6
[77]
liver CASP6
Mean 6.51
Standard deviation 3
Values 3.8 4 9.1 9.2
[78]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[79]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[80]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[81]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[82]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[83]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[84]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[85]
ref_hepatocyte RIPK1
Mean 4.28
Standard deviation 0.89
Values 3.1 4.8 5.4 3.7 4.4
[86]
HepG2 RIPK1
Mean 11.5
Standard deviation 4
Values 14 8.7
[87]
HepG2.C3A RIPK1
Mean 11.5
Standard deviation 0.53
Values 12 11
[88]
HuH.7 RIPK1
Mean 8.85
Standard deviation 0.42
Values 8.8 9.3 8.4
[89]
SNU475 RIPK1
Mean 16.6
Standard deviation 2.9
Values 15 19
[90]
THLE RIPK1
Mean 13.4
Standard deviation 1
Values 13 14
[91]
liver RIPK1
Mean 17
Standard deviation 5.1
Values 22 21 12 13
[92]
ref_hepatocyte CASP9
Mean 2.59
Standard deviation 1
Values 2 4.4 2.7 1.9 1.9
[93]
HepG2 CASP9
Mean 6.38
Standard deviation 0.81
Values 7 5.8
[94]
HepG2.C3A CASP9
Mean 11.1
Standard deviation 0.21
Values 11 11
[95]
HuH.7 CASP9
Mean 5.76
Standard deviation 1.5
Values 6.6 4.1 6.7
[96]
SNU475 CASP9
Mean 5.65
Standard deviation 0.92
Values 5 6.3
[97]
THLE CASP9
Mean 3.94
Standard deviation 0.43
Values 3.6 4.2
[98]
liver CASP9
Mean 2.54
Standard deviation 1.2
Values 1.6 1.9 2.4 4.2
[99]
ref_hepatocyte CASP2
Mean 1.49
Standard deviation 0.81
Values 1.5 1.1 0.94 2.9 1
[100]
HepG2 CASP2
Mean 10.7
Standard deviation 1.9
Values 12 9.4
[101]
HepG2.C3A CASP2
Mean 7.41
Standard deviation 0.75
Values 7.9 6.9
[102]
HuH.7 CASP2
Mean 12.4
Standard deviation 4.7
Values 15 6.9 15
[103]
SNU475 CASP2
Mean 10
Standard deviation 0.13
Values 10 9.9
[104]
THLE CASP2
Mean 15.2
Standard deviation 2.5
Values 13 17
[105]
liver CASP2
Mean 6.36
Standard deviation 2.4
Values 3.8 5.2 7.2 9.2
[106]
ref_hepatocyte APAF1
Mean 1.36
Standard deviation 0.48
Values 1.2 1.1 0.79 1.9 1.8
[107]
HepG2 APAF1
Mean 9.46
Standard deviation 4.9
Values 13 6
[108]
HepG2.C3A APAF1
Mean 11.3
Standard deviation 2.5
Values 13 9.5
[109]
HuH.7 APAF1
Mean 12.9
Standard deviation 2.1
Values 12 12 15
[110]
SNU475 APAF1
Mean 15.4
Standard deviation 1.9
Values 14 17
[111]
THLE APAF1
Mean 9.25
Standard deviation 1.4
Values 8.2 10
[112]
liver APAF1
Mean 5.4
Standard deviation 3.4
Values 8.2 8.5 2.4 2.5
[113]
ref_hepatocyte MAP3K1
Mean 1.15
Standard deviation 0.91
Values 1.1 0.9 0.47 2.7 0.56
[114]
HepG2 MAP3K1
Mean 16
Standard deviation 5.2
Values 20 12
[115]
HepG2.C3A MAP3K1
Mean 11.7
Standard deviation 2.9
Values 14 9.6
[116]
HuH.7 MAP3K1
Mean 9.28
Standard deviation 2.5
Values 6.5 11 10
[117]
SNU475 MAP3K1
Mean 10.6
Standard deviation 2.4
Values 8.9 12
[118]
THLE MAP3K1
Mean 5.47
Standard deviation 0.12
Values 5.5 5.4
[119]
liver MAP3K1
Mean 11.4
Standard deviation 4.8
Values 14 17 7.7 7
[120]
ref_hepatocyte FASLG
Mean 0.0683
Standard deviation 0.15
Values 0 0.34 0 0 0
[121]
HepG2 FASLG
Mean 0.0107
Standard deviation 0.0091
Values 0.0043 0.017
[122]
HepG2.C3A FASLG
Mean 0.035
Standard deviation 0.019
Values 0.021 0.049
[123]
HuH.7 FASLG
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[124]
SNU475 FASLG
Mean 0
Standard deviation 0
Values 0 0
[125]
THLE FASLG
Mean 0
Standard deviation 0
Values 0 0
[126]
liver FASLG
Mean 0.145
Standard deviation 0.073
Values 0.15 0.043 0.19 0.21
[127]
ref_hepatocyte MAPK10
Mean 0.00272
Standard deviation 0.0061
Values 0.014 0 0 0 0
[128]
HepG2 MAPK10
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[129]
HepG2.C3A MAPK10
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 MAPK10
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 MAPK10
Mean 2.4
Standard deviation 0.56
Values 2 2.8
[132]
THLE MAPK10
Mean 0.14
Standard deviation 0.07
Values 0.19 0.09
[133]
liver MAPK10
Mean 0.586
Standard deviation 0.14
Values 0.49 0.8 0.52 0.54