WP_ANGIOTENSIN_II_RECEPTOR_TYPE_1_PATHWAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | AGT | Angiotensinogen | [1] | -1.10[2] | -0.41[3] | -1.58[4] | -6.26[5] | -11.66[6] | 0.31[7] |
2 | F12 | Coagulation factor XII | [8] | -6.50[9] | -4.27[10] | -3.61[11] | -13.29[12] | -8.96[13] | -1.95[14] |
3 | JUND | Transcription factor jun-D | [15] | 0.04[16] | -0.28[17] | -0.05[18] | -2.99[19] | -2.34[20] | -4.40[21] |
4 | HIF1A | Hypoxia-inducible factor 1-alpha | [22] | 0.58[23] | -0.03[24] | 1.20[25] | 2.64[26] | 2.68[27] | -2.35[28] |
5 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | [29] | 1.18[30] | 1.34[31] | 1.72[32] | 1.24[33] | 1.53[34] | -0.28[35] |
6 | IL6ST | Interleukin-6 receptor subunit beta | [36] | 0.99[37] | 1.97[38] | 1.92[39] | 2.08[40] | 2.91[41] | 2.24[42] |
7 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [43] | 0.67[44] | 0.80[45] | 2.50[46] | 0.16[47] | 0.69[48] | -0.44[49] |
8 | RRAS | Ras-related protein R-Ras | [50] | -0.75[51] | -2.01[52] | -1.01[53] | 0.06[54] | -0.26[55] | -3.73[56] |
9 | TGFBR2 | TGF-beta receptor type-2 | [57] | 3.55[58] | 2.74[59] | 2.83[60] | 1.41[61] | 2.79[62] | -0.04[63] |
10 | MAPK1 | Mitogen-activated protein kinase 1 | [64] | 2.44[65] | 2.31[66] | 2.56[67] | 2.20[68] | 1.51[69] | 0.24[70] |
11 | AGTR1 | Type-1 angiotensin II receptor | [71] | -6.62[72] | -5.06[73] | 0.88[74] | -0.92[75] | -5.66[76] | -0.11[77] |
12 | SMAD3 | Mothers against decapentaplegic homolog 3 | [78] | 2.66[79] | 1.79[80] | 2.44[81] | 2.15[82] | 2.69[83] | -1.33[84] |
13 | TGFBR1 | TGF-beta receptor type-1 | [85] | 1.06[86] | 1.02[87] | 0.94[88] | 0.69[89] | 1.46[90] | -0.21[91] |
14 | ACTA2 | Actin, aortic smooth muscle | [92] | 2.85[93] | 2.11[94] | -3.74[95] | 5.40[96] | 0.90[97] | 1.46[98] |
15 | SP1 | Transcription factor Sp1 | [99] | 2.55[100] | 2.52[101] | 4.01[102] | 3.02[103] | 2.37[104] | 0.61[105] |
16 | SMAD4 | Mothers against decapentaplegic homolog 4 | [106] | 2.13[107] | 2.48[108] | 2.87[109] | 2.26[110] | 2.29[111] | 1.25[112] |
17 | TGFB1 | Transforming growth factor beta-1 | [113] | 4.21[114] | 2.89[115] | 0.57[116] | 4.19[117] | 3.08[118] | -2.77[119] |
18 | IL11RA | Interleukin-11 receptor subunit alpha | [120] | -1.24[121] | 0.77[122] | -0.20[123] | -1.19[124] | -1.64[125] | -0.38[126] |
19 | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 | [127] | 1.02[128] | -2.46[129] | 2.82[130] | 1.36[131] | -3.01[132] | -3.16[133] |
20 | COL1A1 | Collagen alpha-1(I) chain | [134] | 5.47[135] | -2.31[136] | -0.07[137] | 7.35[138] | 8.56[139] | 4.81[140] |
21 | COL1A2 | Collagen alpha-2(I) chain | [141] | -5.42[142] | -5.62[143] | -2.70[144] | 5.32[145] | 5.03[146] | 4.88[147] |
22 | ACE2 | Angiotensin-converting enzyme 2 | [148] | 0.42[149] | 1.49[150] | 0.94[151] | -6.67[152] | -6.41[153] | -1.62[154] |
23 | NOX4 | NADPH oxidase 4 | [155] | -2.50[156] | 0.00[157] | 0.62[158] | -2.24[159] | -1.35[160] | 0.56[161] |
24 | IL11 | Interleukin-11 | [162] | 7.22[163] | 3.31[164] | 1.23[165] | 3.53[166] | 3.12[167] | -3.18[168] |
25 | PDGFD | Platelet-derived growth factor D | [169] | 3.10[170] | -1.98[171] | -3.75[172] | 3.18[173] | 4.40[174] | 4.53[175] |
26 | RACK1 | Receptor of activated protein C kinase 1 | [176] | [177] | [178] | [179] | [180] | [181] | [182] |
27 | MAS1 | Proto-oncogene Mas | [183] | [184] | [185] | [186] | [187] | [188] | [189] |
28 | CCN2 | [190] | [191] | [192] | [193] | [194] | [195] | [196] |