WP_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CALR | Calreticulin | [1] | -0.85[2] | -1.07[3] | -1.16[4] | -2.12[5] | -1.37[6] | -0.63[7] |
2 | PRDX1 | Peroxiredoxin-1 | [8] | -1.38[9] | -1.80[10] | -1.21[11] | -1.74[12] | -1.85[13] | -1.77[14] |
3 | RHOA | Transforming protein RhoA | [15] | -0.82[16] | -1.07[17] | -0.68[18] | -1.21[19] | -0.31[20] | -0.96[21] |
4 | RAN | GTP-binding nuclear protein Ran | [22] | -0.25[23] | 0.12[24] | -0.36[25] | -1.14[26] | -0.46[27] | -1.57[28] |
5 | PARK7 | Protein/nucleic acid deglycase DJ-1 | [29] | -1.47[30] | -0.42[31] | -1.49[32] | -1.77[33] | -1.34[34] | -1.27[35] |
6 | RHOB | Rho-related GTP-binding protein RhoB | [36] | -0.68[37] | -1.00[38] | -2.97[39] | -2.28[40] | -2.69[41] | 0.25[42] |
7 | CDC42 | Cell division control protein 42 homolog | [43] | -0.71[44] | 0.26[45] | -0.58[46] | -0.52[47] | -0.80[48] | -1.71[49] |
8 | DSTN | Destrin | [50] | -0.98[51] | -1.14[52] | -2.29[53] | 0.79[54] | -0.78[55] | -1.18[56] |
9 | SUMO1 | Small ubiquitin-related modifier 1 | [57] | -1.48[58] | -1.08[59] | -1.27[60] | -1.46[61] | -1.06[62] | -1.17[63] |
10 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [64] | -0.27[65] | -0.36[66] | 0.52[67] | 0.03[68] | 0.46[69] | -0.60[70] |
11 | NCOA4 | Nuclear receptor coactivator 4 | [71] | 1.08[72] | 2.31[73] | 1.02[74] | 0.28[75] | 0.28[76] | 1.64[77] |
12 | JUN | Transcription factor AP-1 | [78] | -0.37[79] | -1.67[80] | -1.23[81] | -1.69[82] | -0.67[83] | -1.44[84] |
13 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | [85] | 0.96[86] | -0.19[87] | -2.71[88] | -1.97[89] | 1.03[90] | -1.46[91] |
14 | AKT1 | RAC-alpha serine/threonine-protein kinase | [92] | 0.20[93] | 0.21[94] | -0.70[95] | -0.04[96] | 0.43[97] | 0.12[98] |
15 | CTNNB1 | Catenin beta-1 | [99] | 1.74[100] | 1.48[101] | 2.54[102] | 0.77[103] | 1.44[104] | 1.48[105] |
16 | STUB1 | E3 ubiquitin-protein ligase CHIP | [106] | -1.86[107] | -1.60[108] | -2.09[109] | -2.65[110] | -1.88[111] | -1.88[112] |
17 | FKBP4 | Peptidyl-prolyl cis-trans isomerase FKBP4 | [113] | -0.02[114] | -0.20[115] | 1.07[116] | -1.29[117] | 0.54[118] | -0.37[119] |
18 | STAT3 | Signal transducer and activator of transcription 3 | [120] | 0.67[121] | -0.58[122] | 0.32[123] | 0.26[124] | -0.02[125] | 2.78[126] |
19 | SMARCE1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfa | -0.12[127] | -0.05[128] | 0.35[129] | -0.05[130] | -0.22[131] | -0.72[132] | |
20 | NR0B2 | Nuclear receptor subfamily 0 group B member 2 | [133] | -0.30[134] | 1.21[135] | -5.32[136] | -9.55[137] | -9.36[138] | 0.31[139] |
21 | CCND1 | G1/S-specific cyclin-D1 | [140] | 3.17[141] | 0.91[142] | 1.91[143] | 1.89[144] | 0.86[145] | 1.42[146] |
22 | CAV1 | Caveolin-1 | [147] | -6.72[148] | -9.30[149] | -2.85[150] | 1.39[151] | 0.48[152] | -1.63[153] |
23 | HDAC1 | Histone deacetylase 1 | [154] | 0.63[155] | 0.89[156] | 1.74[157] | 0.66[158] | 0.89[159] | -0.09[160] |
24 | TGIF1 | Homeobox protein TGIF1 | [161] | -0.18[162] | -0.58[163] | 0.42[164] | -0.37[165] | -0.29[166] | -1.48[167] |
25 | RELA | Transcription factor p65 | [168] | 0.25[169] | -0.01[170] | 0.30[171] | -0.04[172] | 0.31[173] | -0.51[174] |
26 | DAXX | Death domain-associated protein 6 | [175] | 0.29[176] | 0.39[177] | 0.16[178] | 0.17[179] | 0.49[180] | -0.59[181] |
27 | KDM1A | Lysine-specific histone demethylase 1A | [182] | 1.20[183] | 2.03[184] | 1.71[185] | 0.89[186] | 0.86[187] | -0.46[188] |
28 | FLNA | Filamin-A | [189] | 4.25[190] | 2.96[191] | 0.18[192] | 5.56[193] | 4.64[194] | 2.53[195] |
29 | UBE2I | SUMO-conjugating enzyme UBC9 | [196] | 1.41[197] | 1.33[198] | 1.88[199] | 0.34[200] | 1.35[201] | -0.18[202] |
30 | UBE3A | Ubiquitin-protein ligase E3A | [203] | -0.18[204] | 0.88[205] | 1.07[206] | 0.80[207] | 1.14[208] | 1.59[209] |
31 | RNF4 | E3 ubiquitin-protein ligase RNF4 | [210] | 1.24[211] | 0.90[212] | 2.52[213] | 1.95[214] | 1.41[215] | 0.55[216] |
32 | BAG1 | BAG family molecular chaperone regulator 1 | [217] | 0.10[218] | 0.67[219] | -0.04[220] | -1.08[221] | -0.08[222] | 0.44[223] |
33 | PTK2 | Focal adhesion kinase 1 | [224] | 0.85[225] | 1.59[226] | 2.14[227] | 1.96[228] | 1.61[229] | 1.13[230] |
34 | FHL2 | Four and a half LIM domains protein 2 | [231] | 0.64[232] | 0.15[233] | -6.42[234] | 0.72[235] | 1.18[236] | -1.66[237] |
35 | CARM1 | Histone-arginine methyltransferase CARM1 | [238] | 1.57[239] | 1.26[240] | 1.76[241] | -0.23[242] | 1.00[243] | -0.65[244] |
36 | RNF14 | E3 ubiquitin-protein ligase RNF14 | [245] | -0.31[246] | -0.16[247] | -0.29[248] | 0.65[249] | 1.22[250] | 1.45[251] |
37 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [252] | -0.35[253] | 0.01[254] | 1.27[255] | 2.08[256] | 2.03[257] | 3.37[258] |
38 | RNF6 | E3 ubiquitin-protein ligase RNF6 | [259] | -0.59[260] | 0.63[261] | 0.16[262] | 0.65[263] | 0.84[264] | 0.69[265] |
39 | NCOR1 | Nuclear receptor corepressor 1 | [266] | 1.20[267] | 1.95[268] | 2.76[269] | 1.58[270] | 2.07[271] | 3.17[272] |
40 | KAT5 | Histone acetyltransferase KAT5 | [273] | -0.66[274] | 0.00[275] | -0.86[276] | -0.82[277] | -0.46[278] | -0.70[279] |
41 | ROCK1 | Rho-associated protein kinase 1 | [280] | -0.83[281] | 0.93[282] | 1.88[283] | 1.38[284] | 1.17[285] | 1.95[286] |
42 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protei | -0.42[287] | 1.22[288] | 1.59[289] | -0.55[290] | 1.15[291] | 2.85[292] | |
43 | MDM2 | E3 ubiquitin-protein ligase Mdm2 | [293] | 2.23[294] | 3.89[295] | 1.30[296] | 0.52[297] | 1.84[298] | 2.53[299] |
44 | SMAD3 | Mothers against decapentaplegic homolog 3 | [300] | 2.05[301] | 1.69[302] | 2.09[303] | 1.81[304] | 3.14[305] | 0.58[306] |
45 | EGFR | Epidermal growth factor receptor | [307] | -0.58[308] | -0.71[309] | 2.34[310] | 0.45[311] | 1.51[312] | 3.02[313] |
46 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [314] | 1.99[315] | 2.46[316] | 3.24[317] | 0.72[318] | 1.73[319] | 0.08[320] |
47 | ROCK2 | Rho-associated protein kinase 2 | [321] | 1.59[322] | 3.08[323] | 1.72[324] | 2.65[325] | 0.86[326] | 2.29[327] |
48 | AR | Androgen receptor | [328] | -10.33[329] | -9.41[330] | -11.08[331] | -1.73[332] | -4.32[333] | 4.02[334] |
49 | GSK3B | Glycogen synthase kinase-3 beta | [335] | 1.39[336] | 1.27[337] | 2.01[338] | 1.83[339] | 2.10[340] | 1.53[341] |
50 | SIN3A | Paired amphipathic helix protein Sin3a | [342] | 1.50[343] | 1.83[344] | 3.20[345] | 2.00[346] | 2.20[347] | 1.65[348] |
51 | SRC | Proto-oncogene tyrosine-protein kinase Src | [349] | 3.14[350] | 3.37[351] | 2.54[352] | 2.41[353] | 2.03[354] | -0.48[355] |
52 | LIMK2 | LIM domain kinase 2 | [356] | 1.62[357] | 2.24[358] | 2.56[359] | 0.38[360] | 1.47[361] | 1.65[362] |
53 | SP1 | Transcription factor Sp1 | [363] | 1.94[364] | 2.43[365] | 3.66[366] | 2.68[367] | 2.81[368] | 2.52[369] |
54 | PIAS4 | E3 SUMO-protein ligase PIAS4 | [370] | 0.36[371] | 0.12[372] | 1.04[373] | -0.51[374] | 0.04[375] | -0.04[376] |
55 | CCNE1 | G1/S-specific cyclin-E1 | [377] | 1.36[378] | 1.71[379] | 0.07[380] | -0.39[381] | 0.65[382] | -4.26[383] |
56 | SMAD4 | Mothers against decapentaplegic homolog 4 | [384] | 1.51[385] | 2.39[386] | 2.52[387] | 1.92[388] | 2.74[389] | 3.16[390] |
57 | RB1 | Retinoblastoma-associated protein | [391] | 1.34[392] | 2.08[393] | 2.81[394] | 2.29[395] | 3.06[396] | 1.85[397] |
58 | KAT2B | Histone acetyltransferase KAT2B | [398] | -1.93[399] | -2.80[400] | -0.27[401] | -0.05[402] | 0.82[403] | 2.16[404] |
59 | PIAS1 | E3 SUMO-protein ligase PIAS1 | [405] | 0.16[406] | 0.67[407] | 1.74[408] | 0.89[409] | 1.06[410] | 1.55[411] |
60 | KAT7 | Histone acetyltransferase KAT7 | [412] | 1.66[413] | 1.53[414] | 2.26[415] | 1.93[416] | 2.28[417] | 1.79[418] |
61 | BMF | Bcl-2-modifying factor | [419] | 0.94[420] | 1.55[421] | 2.78[422] | 3.65[423] | -1.26[424] | -0.43[425] |
62 | PATZ1 | POZ-, AT hook-, and zinc finger-containing protein 1 | [426] | 2.20[427] | 2.15[428] | 2.04[429] | 0.23[430] | 0.97[431] | 0.75[432] |
63 | NCOA3 | Nuclear receptor coactivator 3 | [433] | 2.84[434] | 2.49[435] | 2.96[436] | 3.12[437] | 2.51[438] | 3.02[439] |
64 | NCOR2 | Nuclear receptor corepressor 2 | [440] | 3.47[441] | 2.10[442] | 2.38[443] | 4.16[444] | 4.11[445] | 2.26[446] |
65 | EP300 | Histone acetyltransferase p300 | [447] | 2.84[448] | 2.68[449] | 3.74[450] | 2.59[451] | 3.08[452] | 3.12[453] |
66 | ZMIZ1 | Zinc finger MIZ domain-containing protein 1 | [454] | 3.35[455] | 3.19[456] | 3.28[457] | 3.63[458] | 3.34[459] | 2.28[460] |
67 | PSMC3IP | Homologous-pairing protein 2 homolog | [461] | -0.35[462] | 0.14[463] | -0.10[464] | -0.52[465] | 1.01[466] | -3.37[467] |
68 | NCOA1 | Nuclear receptor coactivator 1 | [468] | 0.59[469] | 1.40[470] | 1.76[471] | 1.81[472] | 1.70[473] | 3.02[474] |
69 | RAD9A | Cell cycle checkpoint control protein RAD9A | [475] | 0.19[476] | 0.72[477] | 2.70[478] | 2.34[479] | 0.61[480] | 0.20[481] |
70 | BRCA1 | Breast cancer type 1 susceptibility protein | [482] | 1.79[483] | 3.28[484] | 3.84[485] | 2.16[486] | 3.13[487] | 2.04[488] |
71 | SIRT1 | NAD-dependent protein deacetylase sirtuin-1 | [489] | 0.62[490] | 1.96[491] | 1.69[492] | 1.58[493] | 2.27[494] | 1.71[495] |
72 | CREB1 | Cyclic AMP-responsive element-binding protein 1 | [496] | 1.84[497] | 3.24[498] | 3.90[499] | 2.56[500] | 2.94[501] | 2.71[502] |
73 | CREBBP | CREB-binding protein | [503] | 3.02[504] | 2.48[505] | 3.26[506] | 2.77[507] | 3.22[508] | 3.61[509] |
74 | FOXO1 | Forkhead box protein O1 | [510] | 1.81[511] | 1.72[512] | 2.03[513] | 1.19[514] | 3.65[515] | 3.46[516] |
75 | PIAS2 | E3 SUMO-protein ligase PIAS2 | [517] | 1.30[518] | 2.00[519] | 2.37[520] | 1.70[521] | 2.17[522] | 2.78[523] |
76 | ZNF318 | Zinc finger protein 318 | [524] | 2.40[525] | 3.42[526] | 2.92[527] | 2.65[528] | 2.50[529] | 2.77[530] |
77 | ETV5 | ETS translocation variant 5 | [531] | 3.30[532] | 3.84[533] | 4.14[534] | 1.97[535] | 3.91[536] | 1.87[537] |
78 | PIAS3 | E3 SUMO-protein ligase PIAS3 | [538] | 1.42[539] | 0.85[540] | 2.32[541] | 2.73[542] | 2.87[543] | 1.14[544] |
79 | NCOA2 | Nuclear receptor coactivator 2 | [545] | 1.70[546] | 2.76[547] | 4.76[548] | 3.21[549] | 1.95[550] | 4.97[551] |
80 | NR2C2 | Nuclear receptor subfamily 2 group C member 2 | [552] | 3.36[553] | 4.32[554] | 4.93[555] | 3.72[556] | 4.52[557] | 4.81[558] |
81 | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein | [559] | 4.04[560] | 1.74[561] | -2.31[562] | 5.14[563] | 5.37[564] | 3.97[565] |
82 | PAK6 | Serine/threonine-protein kinase PAK 6 | [566] | -1.56[567] | [568] | 1.59[569] | 2.22[570] | 1.77[571] | -0.71[572] |
83 | EFCAB6 | EF-hand calcium-binding domain-containing protein 6 | [573] | [574] | [575] | [576] | -2.49[577] | 0.58[578] | 3.46[579] |
84 | RUNX2 | Runt-related transcription factor 2 | [580] | -0.73[581] | -0.84[582] | 4.40[583] | 7.14[584] | 9.54[585] | 3.99[586] |
85 | PLPP1 | Phospholipid phosphatase 1 | [587] | [588] | [589] | [590] | [591] | [592] | [593] |
86 | RLN1 | Prorelaxin H1 | [594] | [595] | [596] | [597] | [598] | [599] | [600] |
87 | KLK3 | Prostate-specific antigen | [601] | [602] | [603] | [604] | [605] | [606] | [607] |
88 | BUB1B-PA | BUB1B-PAK6 readthrough (Fragment) | [608] | [609] | [610] | [611] | [612] | [613] | [614] |
89 | RACK1 | Receptor of activated protein C kinase 1 | [615] | [616] | [617] | [618] | [619] | [620] | [621] |
90 | MIR1281 | [622] | [623] | [624] | [625] | [626] | [627] | [628] | |
91 | TLE5 | [629] | [630] | [631] | [632] | [633] | [634] | [635] |