WP_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | SOD1 | Superoxide dismutase [Cu-Zn] | [1] | -2.34[2] | -2.14[3] | -3.18[4] | -2.08[5] | -2.26[6] | -0.86[7] |
2 | CST3 | Cystatin-C | [8] | 0.33[9] | 0.34[10] | -1.28[11] | -1.73[12] | -1.13[13] | 0.36[14] |
3 | GPX1 | Glutathione peroxidase 1 | [15] | -0.46[16] | -0.57[17] | -0.25[18] | -0.66[19] | 0.28[20] | -0.88[21] |
4 | CAT | Catalase | [22] | -0.99[23] | -1.08[24] | -0.64[25] | -1.64[26] | -2.28[27] | 1.15[28] |
5 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [29] | 0.67[30] | 0.56[31] | 1.21[32] | 1.63[33] | 1.59[34] | -0.31[35] |
6 | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A | [36] | 0.59[37] | 0.35[38] | 0.59[39] | 1.98[40] | 2.14[41] | 0.74[42] |
7 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [43] | 1.12[44] | 1.01[45] | 1.82[46] | 0.77[47] | 1.23[48] | -1.04[49] |
8 | TOMM40 | Mitochondrial import receptor subunit TOM40 homolog | [50] | 1.26[51] | 1.26[52] | 1.07[53] | 1.04[54] | 1.07[55] | -0.75[56] |
9 | CCS | Copper chaperone for superoxide dismutase | [57] | -1.16[58] | -1.23[59] | 0.08[60] | -0.68[61] | -1.66[62] | -0.45[63] |
10 | BCL2L1 | Bcl-2-like protein 1 | [64] | 3.20[65] | 2.80[66] | 3.71[67] | 1.00[68] | 1.36[69] | -0.16[70] |
11 | BAX | Apoptosis regulator BAX | [71] | 1.39[72] | 0.81[73] | 0.29[74] | 0.01[75] | 0.37[76] | -3.30[77] |
12 | BAD | Bcl2-associated agonist of cell death | [78] | -0.61[79] | -0.26[80] | -1.27[81] | 0.55[82] | 0.92[83] | -0.76[84] |
13 | DERL1 | Derlin-1 | [85] | 0.64[86] | 0.79[87] | 0.84[88] | 1.81[89] | 1.44[90] | 1.42[91] |
14 | DAXX | Death domain-associated protein 6 | [92] | 1.23[93] | 1.30[94] | 0.85[95] | 1.76[96] | 1.61[97] | -0.30[98] |
15 | RAB5A | Ras-related protein Rab-5A | [99] | 0.19[100] | 0.58[101] | 1.55[102] | 1.37[103] | 1.72[104] | 0.47[105] |
16 | CASP3 | Caspase-3 | [106] | 1.20[107] | 2.09[108] | -0.52[109] | 0.72[110] | 1.69[111] | -0.15[112] |
17 | BID | BH3-interacting domain death agonist | [113] | 0.80[114] | 1.11[115] | 0.68[116] | 1.32[117] | 0.76[118] | 0.83[119] |
18 | MAPK14 | Mitogen-activated protein kinase 14 | [120] | 2.54[121] | 2.82[122] | 2.34[123] | 3.29[124] | 2.75[125] | 1.94[126] |
19 | ALS2 | Alsin | [127] | 1.54[128] | 2.25[129] | 2.85[130] | 2.57[131] | 2.41[132] | 2.40[133] |
20 | TP53 | Cellular tumor antigen p53 | [134] | 2.70[135] | 2.48[136] | 3.18[137] | 2.90[138] | 2.54[139] | 0.62[140] |
21 | PPP3CB | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | 1.55[141] | 2.56[142] | 2.01[143] | 2.37[144] | 2.09[145] | 0.51[146] | |
22 | PPP3CC | Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform | 0.36[147] | 0.71[148] | 0.26[149] | 0.52[150] | 1.42[151] | 0.72[152] | |
23 | CASP1 | Caspase-1 | [153] | -1.97[154] | -5.16[155] | -3.68[156] | 1.69[157] | 1.82[158] | -0.07[159] |
24 | PPP3CA | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 1.79[160] | 1.76[161] | 1.51[162] | 3.56[163] | 3.28[164] | 2.46[165] | |
25 | CASP9 | Caspase-9 | [166] | 1.22[167] | 2.39[168] | 1.46[169] | 1.86[170] | 1.15[171] | 0.12[172] |
26 | SLC1A2 | Excitatory amino acid transporter 2 | [173] | 2.67[174] | 3.68[175] | -2.85[176] | -1.86[177] | -4.25[178] | 5.22[179] |
27 | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 | [180] | 1.35[181] | -1.64[182] | 3.15[183] | 2.62[184] | -1.44[185] | -0.96[186] |
28 | APAF1 | Apoptotic protease-activating factor 1 | [187] | 2.72[188] | 3.36[189] | 3.56[190] | 4.24[191] | 3.32[192] | 2.15[193] |
29 | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 | [194] | -3.23[195] | -5.95[196] | -0.11[197] | -0.25[198] | 4.12[199] | 3.71[200] |
30 | NEFH | Neurofilament heavy polypeptide | [201] | 1.56[202] | -2.58[203] | -2.18[204] | 3.30[205] | -0.43[206] | 0.70[207] |
31 | NEFM | Neurofilament medium polypeptide | [208] | [209] | [210] | [211] | 5.25[212] | -0.53[213] | -4.32[214] |
32 | TNF | Tumor necrosis factor | [215] | 2.16[216] | 0.24[217] | -4.41[218] | -0.61[219] | -3.86[220] | -1.23[221] |
33 | BCL2 | Apoptosis regulator Bcl-2 | [222] | -1.79[223] | 3.83[224] | -3.63[225] | 3.39[226] | 3.08[227] | 3.89[228] |
34 | NOS1 | Nitric oxide synthase, brain | [229] | -0.49[230] | 1.69[231] | 0.06[232] | 0.94[233] | 0.81[234] | 1.35[235] |
35 | NEFL | Neurofilament light polypeptide | [236] | -0.95[237] | [238] | 1.02[239] | 11.28[240] | 3.91[241] | [242] |
36 | PRPH | Peripherin | [243] | 3.46[244] | 4.53[245] | 2.72[246] | 5.06[247] | 4.89[248] | 0.33[249] |
37 | GRIA1 | Glutamate receptor 1 | [250] | -1.26[251] | [252] | [253] | 0.96[254] | 1.37[255] | 0.80[256] |
38 | CASP12 | Inactive caspase-12 | [257] | [258] | [259] | [260] | [261] | [262] | [263] |