WP_ALPHA_6_BETA_4_SIGNALING_PATHWAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RHOA | Transforming protein RhoA | [1] | -1.54[2] | -1.84[3] | -1.75[4] | -2.18[5] | -1.40[6] | -1.51[7] |
2 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [8] | -0.99[9] | -1.12[10] | -0.55[11] | -0.94[12] | -0.63[13] | -1.15[14] |
3 | EIF4EBP1 | Eukaryotic translation initiation factor 4E-binding protein 1 | [15] | -1.59[16] | -1.71[17] | -1.24[18] | -4.26[19] | -2.39[20] | -1.78[21] |
4 | AKT1 | RAC-alpha serine/threonine-protein kinase | [22] | -0.52[23] | -0.55[24] | -1.76[25] | -1.01[26] | -0.66[27] | -0.43[28] |
5 | LAMC2 | Laminin subunit gamma-2 | [29] | -8.93[30] | -9.96[31] | -8.82[32] | -5.93[33] | -4.45[34] | -6.51[35] |
6 | LAMB3 | Laminin subunit beta-3 | [36] | -3.41[37] | -6.07[38] | -4.75[39] | -1.62[40] | -2.26[41] | -2.57[42] |
7 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | [43] | -0.15[44] | 0.47[45] | 0.30[46] | -0.07[47] | 0.89[48] | 1.07[49] |
8 | GRB2 | Growth factor receptor-bound protein 2 | [50] | 0.60[51] | 0.63[52] | 0.62[53] | -0.40[54] | -0.17[55] | 0.11[56] |
9 | SHC1 | SHC-transforming protein 1 | [57] | 0.56[58] | 0.98[59] | 0.93[60] | 1.69[61] | 1.50[62] | 0.60[63] |
10 | ITGA6 | Integrin alpha-6 | [64] | -0.26[65] | 0.33[66] | 0.29[67] | -2.11[68] | -3.41[69] | -0.71[70] |
11 | LAMB2 | Laminin subunit beta-2 | [71] | 1.54[72] | 1.41[73] | 0.23[74] | -0.06[75] | 1.16[76] | 1.91[77] |
12 | HRAS | GTPase HRas | [78] | -1.61[79] | -2.12[80] | -3.04[81] | -1.91[82] | -1.80[83] | -2.84[84] |
13 | MAPK1 | Mitogen-activated protein kinase 1 | [85] | 1.11[86] | 1.45[87] | 1.14[88] | 0.89[89] | 0.86[90] | 1.59[91] |
14 | PTK2 | Focal adhesion kinase 1 | [92] | 0.14[93] | 0.82[94] | 1.07[95] | 0.99[96] | 0.51[97] | 0.58[98] |
15 | LAMC1 | Laminin subunit gamma-1 | [99] | 2.75[100] | 1.21[101] | 1.81[102] | 2.81[103] | 2.77[104] | 1.04[105] |
16 | MAPK14 | Mitogen-activated protein kinase 14 | [106] | 0.87[107] | 1.14[108] | 0.59[109] | 0.73[110] | 0.52[111] | 1.10[112] |
17 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [113] | -1.07[114] | -0.76[115] | 0.20[116] | 1.11[117] | 0.93[118] | 2.82[119] |
18 | SOS1 | Son of sevenless homolog 1 | [120] | -0.70[121] | 1.03[122] | 0.40[123] | -0.11[124] | -0.56[125] | 0.35[126] |
19 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [127] | 1.27[128] | 1.70[129] | 2.17[130] | -0.25[131] | 0.63[132] | -0.47[133] |
20 | MAPK3 | Mitogen-activated protein kinase 3 | [134] | 1.25[135] | 1.49[136] | 1.40[137] | -0.53[138] | -0.19[139] | -1.22[140] |
21 | SRC | Proto-oncogene tyrosine-protein kinase Src | [141] | 2.42[142] | 2.61[143] | 1.47[144] | 1.44[145] | 0.94[146] | -1.03[147] |
22 | PRKCD | Protein kinase C delta type | [148] | 0.50[149] | 0.95[150] | 0.29[151] | -1.46[152] | 0.02[153] | -1.25[154] |
23 | LAMB1 | Laminin subunit beta-1 | [155] | 3.32[156] | 3.07[157] | 4.29[158] | 4.43[159] | 3.94[160] | 2.15[161] |
24 | MTOR | Serine/threonine-protein kinase mTOR | [162] | 1.93[163] | 3.15[164] | 2.58[165] | 1.73[166] | 2.13[167] | 3.27[168] |
25 | IRS1 | Insulin receptor substrate 1 | [169] | 1.49[170] | 1.13[171] | 2.43[172] | 0.75[173] | 0.65[174] | 1.93[175] |
26 | PRKCA | Protein kinase C alpha type | [176] | 2.24[177] | 2.48[178] | 2.70[179] | 1.19[180] | 1.88[181] | 1.73[182] |
27 | LAMA5 | Laminin subunit alpha-5 | [183] | 4.32[184] | 3.72[185] | 3.22[186] | 5.05[187] | 2.91[188] | 2.57[189] |
28 | IRS2 | Insulin receptor substrate 2 | [190] | -6.25[191] | [192] | -3.33[193] | -1.62[194] | 2.53[195] | 2.20[196] |
29 | GAB1 | GRB2-associated-binding protein 1 | [197] | 0.70[198] | 1.99[199] | 1.98[200] | 0.98[201] | 1.16[202] | 2.69[203] |
30 | LAMA3 | Laminin subunit alpha-3 | [204] | 2.93[205] | 2.96[206] | -1.20[207] | 3.52[208] | 1.15[209] | 1.34[210] |
31 | ITGB4 | Integrin beta-4 | [211] | 5.11[212] | 5.38[213] | 1.70[214] | 3.21[215] | 1.39[216] | 2.62[217] |
32 | LAMA1 | Laminin subunit alpha-1 | [218] | 0.12[219] | -2.15[220] | -2.92[221] | 5.70[222] | 6.67[223] | 2.07[224] |
33 | LAMA2 | Laminin subunit alpha-2 | [225] | 4.94[226] | 5.04[227] | 2.63[228] | 9.48[229] | 9.56[230] | 12.89[231] |
34 | MIR4260 | [232] | [233] | [234] | [235] | [236] | [237] | [238] | |
35 | MIR4758 | [239] | [240] | [241] | [242] | [243] | [244] | [245] |