WP_AIRWAY_SMOOTH_MUSCLE_CELL_CONTRACTION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CALM2 | Calmodulin-2 | [1] | -0.90[2] | -0.27[3] | -1.17[4] | -1.31[5] | -0.97[6] | -1.26[7] |
2 | RHOA | Transforming protein RhoA | [8] | -0.33[9] | -1.06[10] | -0.27[11] | -0.79[12] | -0.28[13] | -0.86[14] |
3 | PPP1CB | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | [15] | 0.38[16] | 0.70[17] | 1.36[18] | 1.20[19] | 1.07[20] | 0.96[21] |
4 | CALM1 | Calmodulin-1 | [22] | 0.69[23] | 0.49[24] | 1.52[25] | 2.02[26] | 1.35[27] | 2.08[28] |
5 | GDI1 | Rab GDP dissociation inhibitor alpha | [29] | 0.91[30] | -0.10[31] | 1.00[32] | 1.34[33] | 1.49[34] | -0.20[35] |
6 | MYLK | Myosin light chain kinase, smooth muscle | [36] | -0.14[37] | -0.02[38] | -0.08[39] | 2.72[40] | 0.37[41] | 3.48[42] |
7 | ROCK1 | Rho-associated protein kinase 1 | [43] | -0.34[44] | 0.94[45] | 2.29[46] | 1.80[47] | 1.19[48] | 2.04[49] |
8 | ROCK2 | Rho-associated protein kinase 2 | [50] | 2.09[51] | 3.09[52] | 2.13[53] | 3.07[54] | 0.89[55] | 2.39[56] |
9 | ADRB2 | Beta-2 adrenergic receptor | [57] | -6.90[58] | [59] | [60] | -2.96[61] | -3.53[62] | 0.67[63] |
10 | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3 | [64] | 5.91[65] | 4.52[66] | 3.57[67] | 2.79[68] | 5.01[69] | 0.69[70] |
11 | GNAQ | Guanine nucleotide-binding protein G(q) subunit alpha | [71] | 0.69[72] | 1.23[73] | 2.31[74] | 2.03[75] | 2.29[76] | 1.90[77] |
12 | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | [78] | 3.40[79] | 4.79[80] | 4.78[81] | 1.22[82] | 1.76[83] | 2.95[84] |
13 | CD38 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | [85] | -7.85[86] | [87] | -4.06[88] | -3.20[89] | -2.05[90] | 1.37[91] |
14 | PPP1R14A | Protein phosphatase 1 regulatory subunit 14A | [92] | -4.89[93] | -6.10[94] | 3.04[95] | 0.55[96] | -3.07[97] | 2.07[98] |
15 | MYL1 | Myosin light chain 1/3, skeletal muscle isoform | [99] | [100] | [101] | [102] | -4.26[103] | [104] | -1.35[105] |
16 | RYR1 | Ryanodine receptor 1 | [106] | 2.10[107] | -2.20[108] | 0.56[109] | 3.84[110] | 2.51[111] | 5.36[112] |
17 | IL13 | Interleukin-13 | [113] | [114] | [115] | [116] | [117] | [118] | [119] |