WP_AFLATOXIN_B1_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 EPHX1 Epoxide hydrolase 1 [1] 0.70[2] -0.42[3] 0.11[4] 1.03[5] 0.38[6] -0.95[7]
2 CYP3A4 Cytochrome P450 3A4 [8] -8.01[9] -7.76[10] -8.10[11] -14.30[12] -10.12[13] 0.74[14]
3 CYP1A2 Cytochrome P450 1A2 [15] -7.18[16] -5.52[17] -4.79[18] -7.87[19] -5.65[20] -1.65[21]
4 AKR7A3 Aflatoxin B1 aldehyde reductase member 3 [22] -5.50[23] -2.66[24] -4.10[25] -6.75[26] -4.32[27] -0.83[28]
5 AKR7A2 Aflatoxin B1 aldehyde reductase member 2 [29] 4.08[30] 5.27[31] 4.42[32] 1.84[33] 4.65[34] 0.52[35]
6 GSTM1 Glutathione S-transferase Mu 1 [36] 1.42[37] 0.51[38] 8.05[39] 6.30[40] 0.53[41] 6.56[42]
7 CYP2A13 Cytochrome P450 2A13 [43] [44] [45] [46] [47] [48] -0.51[49]
[1]
ref_hepatocyte EPHX1
Mean 300
Standard deviation 3.6e+02
Values 48 6.7e+02 7.2e+02 43 21
[2]
HepG2 EPHX1
Mean 80.5
Standard deviation 9
Values 74 87
[3]
HepG2.C3A EPHX1
Mean 25.6
Standard deviation 6.3
Values 21 30
[4]
HuH.7 EPHX1
Mean 13.6
Standard deviation 1.2
Values 12 14 14
[5]
SNU475 EPHX1
Mean 243
Standard deviation 68
Values 2e+02 2.9e+02
[6]
THLE EPHX1
Mean 27.8
Standard deviation 0.14
Values 28 28
[7]
liver EPHX1
Mean 220
Standard deviation 1.4e+02
Values 61 3.1e+02 1.4e+02 3.7e+02
[8]
ref_hepatocyte CYP3A4
Mean 259
Standard deviation 4.1e+02
Values 11 9.6e+02 3.2e+02 0.24 11
[9]
HepG2 CYP3A4
Mean 0.167
Standard deviation 0.098
Values 0.24 0.097
[10]
HepG2.C3A CYP3A4
Mean 0.136
Standard deviation 0.096
Values 0.2 0.068
[11]
HuH.7 CYP3A4
Mean 0.0397
Standard deviation 0.029
Values 0.047 0.064 0.0082
[12]
SNU475 CYP3A4
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[13]
THLE CYP3A4
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[14]
liver CYP3A4
Mean 610
Standard deviation 5.3e+02
Values 49 6.4e+02 4.3e+02 1.3e+03
[15]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.97 3e+02 71 0.4 18
[16]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.13 0.052
[17]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.15 0.24
[18]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.15 0.1 0.11
[19]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.2 0.07
[20]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[21]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 19 12 55 58
[22]
ref_hepatocyte AKR7A3
Mean 38.6
Standard deviation 35
Values 23 90 57 0 23
[23]
HepG2 AKR7A3
Mean 0.141
Standard deviation 0.011
Values 0.13 0.15
[24]
HepG2.C3A AKR7A3
Mean 0.698
Standard deviation 0.47
Values 0.36 1
[25]
HuH.7 AKR7A3
Mean 0.0946
Standard deviation 0.013
Values 0.084 0.11 0.09
[26]
SNU475 AKR7A3
Mean 0.142
Standard deviation 0.036
Values 0.12 0.17
[27]
THLE AKR7A3
Mean 0.138
Standard deviation 0.09
Values 0.2 0.074
[28]
liver AKR7A3
Mean 30.8
Standard deviation 15
Values 13 24 47 39
[29]
ref_hepatocyte AKR7A2
Mean 11.8
Standard deviation 5.8
Values 4 20 15 10 10
[30]
HepG2 AKR7A2
Mean 33
Standard deviation 5.4
Values 37 29
[31]
HepG2.C3A AKR7A2
Mean 51.9
Standard deviation 2.5
Values 54 50
[32]
HuH.7 AKR7A2
Mean 10.6
Standard deviation 1.8
Values 12 8.7 11
[33]
SNU475 AKR7A2
Mean 16.7
Standard deviation 2.4
Values 15 18
[34]
THLE AKR7A2
Mean 21
Standard deviation 4.1
Values 18 24
[35]
liver AKR7A2
Mean 23.9
Standard deviation 13
Values 14 13 27 42
[36]
ref_hepatocyte GSTM1
Mean 0.404
Standard deviation 0.25
Values 0 0.36 0.52 0.52 0.62
[37]
HepG2 GSTM1
Mean 0.18
Standard deviation 0.14
Values 0.28 0.08
[38]
HepG2.C3A GSTM1
Mean 0.0657
Standard deviation 0.017
Values 0.054 0.078
[39]
HuH.7 GSTM1
Mean 4.5
Standard deviation 1.1
Values 4.7 3.3 5.5
[40]
SNU475 GSTM1
Mean 12.6
Standard deviation 6.3
Values 8.2 17
[41]
THLE GSTM1
Mean 0.0417
Standard deviation 0.0088
Values 0.035 0.048
[42]
liver GSTM1
Mean 54
Standard deviation 35
Values 38 15 93 70
[43]
ref_hepatocyte CYP2A13
Mean 0.0683
Standard deviation 0.12
Values 0 0.057 0.28 0 0
[44]
HepG2 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[45]
HepG2.C3A CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 CYP2A13
Mean 0
Standard deviation 0
Values 0 0 0
[47]
SNU475 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[48]
THLE CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[49]
liver CYP2A13
Mean 0.0677
Standard deviation 0.059
Values 0.04 0.13 0 0.1