WP_ADIPOGENESIS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | AGT | Angiotensinogen | [1] | -1.52[2] | -0.76[3] | -2.27[4] | -5.81[5] | -11.74[6] | 1.10[7] |
2 | MIF | Macrophage migration inhibitory factor | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | SCD | Acyl-CoA desaturase | [15] | -0.32[16] | 1.31[17] | 2.17[18] | -2.18[19] | -3.96[20] | -0.25[21] |
4 | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | [22] | -8.74[23] | -4.68[24] | -12.28[25] | [26] | -16.81[27] | 0.30[28] |
5 | PCK2 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | [29] | -0.27[30] | -1.87[31] | -1.10[32] | -4.59[33] | -3.43[34] | -1.03[35] |
6 | SERPINE1 | Plasminogen activator inhibitor 1 | [36] | 1.44[37] | 1.47[38] | -5.19[39] | -3.00[40] | 2.80[41] | -4.63[42] |
7 | PLIN2 | Perilipin-2 | [43] | 1.56[44] | 1.20[45] | -0.15[46] | -2.06[47] | 1.02[48] | 0.57[49] |
8 | LMNA | Prelamin-A/C | [50] | 0.17[51] | -0.58[52] | -1.87[53] | 1.32[54] | -0.32[55] | -1.72[56] |
9 | HMGA1 | High mobility group protein HMG-I/HMG-Y | [57] | 1.04[58] | -0.21[59] | 0.36[60] | 0.03[61] | 0.31[62] | -5.62[63] |
10 | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta | [64] | -3.87[65] | -4.82[66] | -3.52[67] | -3.22[68] | -3.10[69] | -2.92[70] |
11 | NAMPT | Nicotinamide phosphoribosyltransferase | [71] | -2.41[72] | -2.00[73] | -1.34[74] | -0.09[75] | 1.41[76] | 0.23[77] |
12 | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha | [78] | -2.16[79] | -3.43[80] | -3.16[81] | -3.19[82] | -2.32[83] | -3.76[84] |
13 | AGPAT2 | 1-acyl-sn-glycerol-3-phosphate acyltransferase beta | [85] | -2.19[86] | -2.02[87] | -1.69[88] | -2.25[89] | -2.61[90] | -0.95[91] |
14 | CEBPD | CCAAT/enhancer-binding protein delta | [92] | -4.17[93] | -1.90[94] | -1.15[95] | -2.81[96] | -2.75[97] | -2.64[98] |
15 | GTF3A | Transcription factor IIIA | [99] | -0.82[100] | -0.73[101] | -0.69[102] | -0.76[103] | -1.91[104] | -1.21[105] |
16 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | [106] | 1.15[107] | -0.44[108] | -3.05[109] | -1.19[110] | 0.50[111] | -2.59[112] |
17 | KLF6 | Krueppel-like factor 6 | [113] | -0.53[114] | -0.56[115] | -1.64[116] | -0.49[117] | -1.22[118] | -1.48[119] |
18 | CEBPB | CCAAT/enhancer-binding protein beta | [120] | -0.87[121] | -1.70[122] | -1.58[123] | -0.61[124] | -0.54[125] | -2.43[126] |
19 | CTNNB1 | Catenin beta-1 | [127] | 1.93[128] | 1.23[129] | 2.20[130] | 1.56[131] | 0.92[132] | 0.35[133] |
20 | CEBPA | CCAAT/enhancer-binding protein alpha | [134] | 0.64[135] | -0.76[136] | 1.55[137] | -6.22[138] | -7.43[139] | -0.79[140] |
21 | TRIB3 | Tribbles homolog 3 | [141] | 1.22[142] | 1.31[143] | 0.28[144] | -1.21[145] | -1.57[146] | -1.17[147] |
22 | STAT3 | Signal transducer and activator of transcription 3 | [148] | 0.86[149] | -0.83[150] | -0.02[151] | 1.04[152] | -0.55[153] | 1.65[154] |
23 | SREBF1 | Sterol regulatory element-binding protein 1 | [155] | -0.47[156] | -0.38[157] | 0.25[158] | -0.74[159] | -1.43[160] | -0.26[161] |
24 | HIF1A | Hypoxia-inducible factor 1-alpha | [162] | 0.15[163] | -0.37[164] | 0.51[165] | 3.09[166] | 2.60[167] | -1.56[168] |
25 | DDIT3 | DNA damage-inducible transcript 3 protein | [169] | -1.67[170] | -1.10[171] | -1.19[172] | -1.30[173] | -1.29[174] | -2.94[175] |
26 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [176] | 0.23[177] | -0.88[178] | 0.31[179] | 3.33[180] | 0.20[181] | 0.20[182] |
27 | IGF1 | Insulin-like growth factor I | [183] | -8.11[184] | -9.24[185] | -7.38[186] | -0.74[187] | -9.44[188] | 0.17[189] |
28 | IL6ST | Interleukin-6 receptor subunit beta | [190] | 0.57[191] | 1.62[192] | 1.23[193] | 2.53[194] | 2.83[195] | 3.03[196] |
29 | ZMPSTE24 | CAAX prenyl protease 1 homolog | [197] | 0.21[198] | 0.00[199] | 0.10[200] | 1.05[201] | 0.20[202] | -0.49[203] |
30 | ID3 | DNA-binding protein inhibitor ID-3 | [204] | 1.77[205] | 0.68[206] | -1.38[207] | 2.77[208] | 1.12[209] | -1.29[210] |
31 | STAT6 | Signal transducer and activator of transcription 6 | [211] | 0.66[212] | 0.71[213] | -0.30[214] | 1.65[215] | 0.68[216] | -0.06[217] |
32 | NR1H3 | Oxysterols receptor LXR-alpha | [218] | -1.36[219] | -0.53[220] | 0.48[221] | -1.93[222] | -4.15[223] | -1.06[224] |
33 | RXRA | Retinoic acid receptor RXR-alpha | [225] | 0.25[226] | -0.14[227] | 0.78[228] | 0.81[229] | -0.39[230] | 1.40[231] |
34 | EPAS1 | Endothelial PAS domain-containing protein 1 | [232] | 3.01[233] | 2.03[234] | 1.77[235] | 0.23[236] | 2.38[237] | 1.17[238] |
35 | MBNL1 | Muscleblind-like protein 1 | [239] | -0.91[240] | 0.16[241] | 0.12[242] | 2.44[243] | 0.90[244] | 0.48[245] |
36 | KLF15 | Krueppel-like factor 15 | [246] | -3.49[247] | -5.58[248] | -0.60[249] | -9.77[250] | -4.11[251] | -0.63[252] |
37 | DVL1 | Segment polarity protein dishevelled homolog DVL-1 | [253] | 1.11[254] | 1.37[255] | 0.33[256] | 0.87[257] | 0.04[258] | -1.51[259] |
38 | CISD1 | CDGSH iron-sulfur domain-containing protein 1 | [260] | -0.67[261] | 0.42[262] | 0.20[263] | 0.00[264] | -1.05[265] | -0.42[266] |
39 | SOCS3 | Suppressor of cytokine signaling 3 | [267] | -3.83[268] | -4.44[269] | -2.64[270] | 0.00[271] | -1.94[272] | -0.62[273] |
40 | FAS | Tumor necrosis factor receptor superfamily member 6 | [274] | -1.29[275] | -0.71[276] | -8.64[277] | -0.94[278] | -1.29[279] | -2.48[280] |
41 | E2F4 | Transcription factor E2F4 | [281] | 1.44[282] | 1.36[283] | 0.46[284] | 1.22[285] | 0.35[286] | -1.00[287] |
42 | BSCL2 | Seipin | [288] | -5.22[289] | -4.69[290] | -5.49[291] | -4.21[292] | -4.11[293] | -5.00[294] |
43 | PPARD | Peroxisome proliferator-activated receptor delta | [295] | -0.06[296] | -0.80[297] | -0.98[298] | 0.88[299] | 0.43[300] | -2.38[301] |
44 | LPIN2 | Phosphatidate phosphatase LPIN2 | [302] | 1.43[303] | 1.87[304] | 2.59[305] | 1.57[306] | 0.22[307] | 1.88[308] |
45 | CELF1 | CUGBP Elav-like family member 1 | [309] | 1.50[310] | 1.29[311] | 1.85[312] | 1.58[313] | 0.83[314] | 1.33[315] |
46 | NR3C1 | Glucocorticoid receptor | [316] | 0.34[317] | -0.27[318] | 0.11[319] | 2.27[320] | 1.52[321] | 1.02[322] |
47 | NCOR1 | Nuclear receptor corepressor 1 | [323] | 1.39[324] | 1.69[325] | 2.43[326] | 2.37[327] | 1.54[328] | 2.05[329] |
48 | LPIN1 | Phosphatidate phosphatase LPIN1 | [330] | -1.28[331] | 0.35[332] | -0.64[333] | 1.32[334] | -0.48[335] | 0.69[336] |
49 | RBL2 | Retinoblastoma-like protein 2 | [337] | 1.15[338] | 1.80[339] | 1.93[340] | 2.03[341] | 0.87[342] | 1.39[343] |
50 | SMAD3 | Mothers against decapentaplegic homolog 3 | [344] | 2.24[345] | 1.44[346] | 1.75[347] | 2.60[348] | 2.61[349] | -0.54[350] |
51 | STAT2 | Signal transducer and activator of transcription 2 | [351] | 0.34[352] | 1.51[353] | 0.74[354] | 2.33[355] | 0.92[356] | 2.27[357] |
52 | BMP2 | Bone morphogenetic protein 2 | [358] | -4.67[359] | -8.00[360] | 1.18[361] | -1.08[362] | -1.71[363] | -2.94[364] |
53 | HNF1A | Hepatocyte nuclear factor 1-alpha | [365] | 1.22[366] | 1.35[367] | 2.12[368] | -2.57[369] | -4.29[370] | -0.56[371] |
54 | DLK1 | Protein delta homolog 1 | [372] | 1.76[373] | 4.40[374] | -6.82[375] | -7.47[376] | -8.80[377] | -5.52[378] |
55 | RARA | Retinoic acid receptor alpha | [379] | 0.92[380] | -0.71[381] | -0.08[382] | 1.97[383] | 0.56[384] | -0.60[385] |
56 | WWTR1 | WW domain-containing transcription regulator protein 1 | [386] | 2.20[387] | 1.59[388] | 0.68[389] | 3.11[390] | 1.56[391] | -0.02[392] |
57 | BMP1 | Bone morphogenetic protein 1 | [393] | 1.04[394] | -0.65[395] | -1.24[396] | 2.91[397] | 1.46[398] | 0.17[399] |
58 | AHR | Aryl hydrocarbon receptor | [400] | 1.43[401] | 1.53[402] | 2.63[403] | 1.35[404] | 1.39[405] | 1.84[406] |
59 | STAT5B | Signal transducer and activator of transcription 5B | [407] | 1.67[408] | 1.10[409] | 1.88[410] | 2.35[411] | 0.62[412] | 0.87[413] |
60 | GATA4 | Transcription factor GATA-4 | [414] | 1.09[415] | 0.84[416] | 2.34[417] | -0.42[418] | 1.65[419] | -0.17[420] |
61 | PPARA | Peroxisome proliferator-activated receptor alpha | [421] | 0.98[422] | 1.76[423] | 2.70[424] | 0.84[425] | -0.87[426] | 3.40[427] |
62 | MEF2A | Myocyte-specific enhancer factor 2A | [428] | 0.28[429] | 0.87[430] | 1.63[431] | 1.97[432] | 1.19[433] | 1.40[434] |
63 | PPARG | Peroxisome proliferator-activated receptor gamma | [435] | 0.22[436] | 1.64[437] | 2.23[438] | 1.65[439] | 0.75[440] | -1.13[441] |
64 | SP1 | Transcription factor Sp1 | [442] | 2.13[443] | 2.18[444] | 3.32[445] | 3.47[446] | 2.29[447] | 1.40[448] |
65 | NRIP1 | Nuclear receptor-interacting protein 1 | [449] | 1.92[450] | 3.01[451] | 1.85[452] | 3.73[453] | 2.06[454] | 1.86[455] |
66 | PNPLA3 | Patatin-like phospholipase domain-containing protein 3 | [456] | -0.83[457] | 1.18[458] | 2.00[459] | -1.46[460] | -3.58[461] | 1.50[462] |
67 | RB1 | Retinoblastoma-associated protein | [463] | 1.53[464] | 1.83[465] | 2.47[466] | 3.08[467] | 2.53[468] | 0.72[469] |
68 | IRS1 | Insulin receptor substrate 1 | [470] | 2.40[471] | 1.65[472] | 3.16[473] | 2.51[474] | 1.22[475] | 1.36[476] |
69 | NCOR2 | Nuclear receptor corepressor 2 | [477] | 3.66[478] | 1.85[479] | 2.04[480] | 4.95[481] | 3.58[482] | 1.14[483] |
70 | E2F1 | Transcription factor E2F1 | [484] | 2.25[485] | 1.92[486] | 2.13[487] | 2.67[488] | 2.24[489] | -4.37[490] |
71 | MEF2D | Myocyte-specific enhancer factor 2D | [491] | 1.05[492] | 0.72[493] | 1.52[494] | 3.38[495] | 2.09[496] | 0.10[497] |
72 | STAT5A | Signal transducer and activator of transcription 5A | [498] | -1.64[499] | -0.66[500] | -1.51[501] | -0.05[502] | -0.15[503] | -0.52[504] |
73 | KLF7 | Krueppel-like factor 7 | [505] | 0.59[506] | -5.31[507] | 1.57[508] | 2.68[509] | 1.96[510] | 0.48[511] |
74 | TGFB1 | Transforming growth factor beta-1 | [512] | 3.78[513] | 2.55[514] | -0.12[515] | 4.64[516] | 3.00[517] | -1.98[518] |
75 | IRS2 | Insulin receptor substrate 2 | [519] | -5.34[520] | [521] | -2.60[522] | 0.14[523] | 3.09[524] | 1.63[525] |
76 | SOCS1 | Suppressor of cytokine signaling 1 | [526] | -1.14[527] | -0.47[528] | -0.12[529] | -0.99[530] | -3.24[531] | -2.22[532] |
77 | NCOA1 | Nuclear receptor coactivator 1 | [533] | 0.77[534] | 1.14[535] | 1.42[536] | 2.59[537] | 1.18[538] | 1.90[539] |
78 | PLIN1 | Perilipin-1 | [540] | -3.56[541] | -3.36[542] | -4.22[543] | -3.44[544] | -5.00[545] | 1.26[546] |
79 | CFD | Complement factor D | [547] | 0.34[548] | 0.50[549] | 0.32[550] | -0.86[551] | -3.99[552] | -0.78[553] |
80 | PPARGC1 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | -0.78[554] | 1.91[555] | -8.78[556] | 1.56[557] | -2.61[558] | 2.68[559] | |
81 | CREB1 | Cyclic AMP-responsive element-binding protein 1 | [560] | 2.03[561] | 2.99[562] | 3.56[563] | 3.34[564] | 2.42[565] | 1.59[566] |
82 | FOXO1 | Forkhead box protein O1 | [567] | 2.00[568] | 1.47[569] | 1.69[570] | 1.98[571] | 3.12[572] | 2.34[573] |
83 | BMP4 | Bone morphogenetic protein 4 | [574] | 4.79[575] | 3.83[576] | 0.84[577] | 2.80[578] | -0.20[579] | -1.94[580] |
84 | RORA | Nuclear receptor ROR-alpha | [581] | 0.60[582] | 2.59[583] | 0.88[584] | -2.39[585] | -1.87[586] | 3.59[587] |
85 | LPIN3 | Phosphatidate phosphatase LPIN3 | [588] | 1.88[589] | 2.71[590] | 0.90[591] | 2.21[592] | 0.93[593] | 2.91[594] |
86 | LIF | Leukemia inhibitory factor | [595] | 2.59[596] | 2.23[597] | 3.14[598] | 2.42[599] | 2.57[600] | -5.93[601] |
87 | SFRP4 | Secreted frizzled-related protein 4 | [602] | -1.87[603] | -2.81[604] | [605] | -0.14[606] | -4.68[607] | -5.37[608] |
88 | CNTFR | Ciliary neurotrophic factor receptor subunit alpha | [609] | -6.34[610] | [611] | -2.22[612] | -2.66[613] | -6.18[614] | -1.98[615] |
89 | IL6 | Interleukin-6 | [616] | -8.13[617] | [618] | -4.64[619] | -0.05[620] | 1.59[621] | [622] |
90 | KLF5 | Krueppel-like factor 5 | [623] | 1.93[624] | -0.88[625] | 4.05[626] | 1.84[627] | 1.42[628] | -3.86[629] |
91 | NCOA2 | Nuclear receptor coactivator 2 | [630] | 1.89[631] | 2.51[632] | 4.42[633] | 4.00[634] | 1.43[635] | 3.85[636] |
92 | RBL1 | Retinoblastoma-like protein 1 | [637] | 2.09[638] | 2.76[639] | 1.47[640] | 3.61[641] | 3.08[642] | -0.07[643] |
93 | WNT5B | Protein Wnt-5b | [644] | -4.63[645] | -6.00[646] | 0.64[647] | 2.37[648] | -2.30[649] | -1.96[650] |
94 | LIFR | Leukemia inhibitory factor receptor | [651] | 1.23[652] | 3.73[653] | 4.38[654] | 4.87[655] | 3.49[656] | 5.77[657] |
95 | PRLR | Prolactin receptor | [658] | 1.15[659] | 1.13[660] | 5.06[661] | -4.21[662] | -3.94[663] | 3.15[664] |
96 | NR2F1 | COUP transcription factor 1 | [665] | 2.51[666] | 3.62[667] | 4.86[668] | 5.36[669] | 4.54[670] | 1.06[671] |
97 | SLC2A4 | Solute carrier family 2, facilitated glucose transporter member 4 | [672] | 2.14[673] | 2.18[674] | 2.88[675] | -1.33[676] | -2.93[677] | 0.68[678] |
98 | EGR2 | E3 SUMO-protein ligase EGR2 | [679] | -1.43[680] | -3.75[681] | -4.07[682] | -0.83[683] | -1.42[684] | -1.25[685] |
99 | FZD1 | Frizzled-1 | [686] | 1.86[687] | -0.30[688] | 3.46[689] | 3.22[690] | 3.48[691] | 2.03[692] |
100 | CYP26A1 | Cytochrome P450 26A1 | [693] | 3.47[694] | -2.56[695] | 1.07[696] | 0.95[697] | -5.61[698] | 0.25[699] |
101 | PTGIS | Prostacyclin synthase | [700] | -1.25[701] | -0.32[702] | 3.73[703] | 1.92[704] | 7.00[705] | 4.09[706] |
102 | LPL | Lipoprotein lipase | [707] | [708] | [709] | -7.21[710] | 1.37[711] | -3.14[712] | -0.99[713] |
103 | ASIP | Agouti-signaling protein | [714] | -1.66[715] | -1.97[716] | -1.97[717] | -1.29[718] | [719] | -2.51[720] |
104 | NDN | Necdin | [721] | -3.41[722] | -3.34[723] | -2.79[724] | 7.75[725] | 4.17[726] | 2.25[727] |
105 | MEF2C | Myocyte-specific enhancer factor 2C | [728] | -2.80[729] | -1.87[730] | 3.17[731] | 6.41[732] | 1.53[733] | 4.54[734] |
106 | TNF | Tumor necrosis factor | [735] | 1.41[736] | -0.92[737] | -5.44[738] | -1.42[739] | -5.51[740] | -2.64[741] |
107 | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 | [742] | -3.88[743] | [744] | 2.91[745] | 2.11[746] | 1.36[747] | 0.46[748] |
108 | OSM | Oncostatin-M | [749] | -4.99[750] | -0.62[751] | -5.29[752] | -4.41[753] | -5.21[754] | -2.49[755] |
109 | GATA2 | Endothelial transcription factor GATA-2 | [756] | 6.83[757] | 4.38[758] | 4.08[759] | 6.80[760] | 5.09[761] | 0.56[762] |
110 | SPOCK1 | Testican-1 | [763] | 4.46[764] | -4.74[765] | -2.11[766] | 4.70[767] | 7.95[768] | -1.41[769] |
111 | LIPE | Hormone-sensitive lipase | [770] | -4.54[771] | [772] | -0.12[773] | 2.85[774] | 1.97[775] | 1.38[776] |
112 | ADIPOQ | Adiponectin | [777] | -1.21[778] | -1.20[779] | -1.35[780] | -0.07[781] | -1.94[782] | -1.50[783] |
113 | FRZB | Secreted frizzled-related protein 3 | [784] | -1.59[785] | 0.86[786] | 1.71[787] | 2.28[788] | 0.67[789] | 2.25[790] |
114 | BMP3 | Bone morphogenetic protein 3 | [791] | -0.51[792] | 0.85[793] | 0.46[794] | -0.34[795] | 0.31[796] | -0.02[797] |
115 | LEP | Leptin | [798] | -1.02[799] | -0.24[800] | -0.69[801] | -0.05[802] | -2.25[803] | 1.55[804] |
116 | RXRG | Retinoic acid receptor RXR-gamma | [805] | -3.42[806] | [807] | [808] | -1.26[809] | [810] | 1.75[811] |
117 | CYP26B1 | Cytochrome P450 26B1 | [812] | 5.20[813] | 1.95[814] | 9.24[815] | 7.51[816] | 5.87[817] | 4.78[818] |
118 | IRS4 | Insulin receptor substrate 4 | [819] | [820] | [821] | [822] | -0.76[823] | -2.72[824] | [825] |
119 | FOXC2 | Forkhead box protein C2 | [826] | [827] | [828] | [829] | [830] | [831] | [832] |
120 | GH1 | Somatotropin | [833] | [834] | [835] | [836] | [837] | [838] | [839] |
121 | UCP1 | Mitochondrial brown fat uncoupling protein 1 | [840] | [841] | [842] | [843] | [844] | [845] | [846] |
122 | MIXL1 | Homeobox protein MIXL1 | [847] | [848] | [849] | [850] | [851] | [852] | [853] |
123 | INS | Insulin | [854] | [855] | [856] | [857] | [858] | [859] | [860] |
124 | WNT10B | Protein Wnt-10b | [861] | [862] | [863] | [864] | [865] | [866] | [867] |
125 | EBF1 | Transcription factor COE1 | [868] | [869] | [870] | [871] | [872] | [873] | [874] |
126 | MIR6808 | [875] | [876] | [877] | [878] | [879] | [880] | [881] | |
127 | TWIST1 | Twist-related protein 1 | [882] | [883] | [884] | [885] | [886] | [887] | [888] |
128 | RETN | Resistin | [889] | [890] | [891] | [892] | [893] | [894] | [895] |
129 | BORCS8- | BORCS8-MEF2B readthrough | [896] | [897] | [898] | [899] | [900] | [901] | [902] |
130 | WNT1 | Proto-oncogene Wnt-1 | [903] | [904] | [905] | [906] | [907] | [908] | [909] |
131 | GDF10 | Growth/differentiation factor 10 | [910] | [911] | [912] | [913] | [914] | [915] | [916] |