WP_ACUTE_VIRAL_MYOCARDITIS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | ACTB | Actin, cytoplasmic 1 | [1] | -1.19[2] | -1.49[3] | -1.01[4] | -0.87[5] | -0.69[6] | -0.63[7] |
2 | KRT8 | Keratin, type II cytoskeletal 8 | [8] | 0.39[9] | 0.17[10] | -1.26[11] | 0.30[12] | -1.54[13] | -1.67[14] |
3 | PABPC1 | Polyadenylate-binding protein 1 | [15] | -0.45[16] | 0.32[17] | 0.93[18] | -0.75[19] | -0.22[20] | -1.07[21] |
4 | EIF4G2 | Eukaryotic translation initiation factor 4 gamma 2 | [22] | 0.71[23] | 1.52[24] | 1.48[25] | 1.17[26] | 0.93[27] | 1.08[28] |
5 | EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1 | [29] | 1.08[30] | 0.66[31] | 0.93[32] | 0.51[33] | 1.46[34] | 1.60[35] |
6 | AKT1 | RAC-alpha serine/threonine-protein kinase | [36] | 0.28[37] | 0.43[38] | -0.80[39] | 0.08[40] | 0.66[41] | 0.30[42] |
7 | PARP1 | Poly [ADP-ribose] polymerase 1 | [43] | 0.33[44] | 0.46[45] | 1.06[46] | 0.66[47] | 0.73[48] | 0.14[49] |
8 | ILK | Integrin-linked protein kinase | [50] | -0.60[51] | -0.28[52] | -0.50[53] | -0.32[54] | -0.65[55] | -0.91[56] |
9 | STAT3 | Signal transducer and activator of transcription 3 | [57] | 0.75[58] | -0.37[59] | 0.22[60] | 0.37[61] | 0.20[62] | 2.95[63] |
10 | BCL2L1 | Bcl-2-like protein 1 | [64] | 2.34[65] | 2.11[66] | 2.92[67] | -0.49[68] | 0.46[69] | -0.27[70] |
11 | BAX | Apoptosis regulator BAX | [71] | 0.53[72] | 0.12[73] | -0.49[74] | -1.47[75] | -0.53[76] | -3.41[77] |
12 | CCND1 | G1/S-specific cyclin-D1 | [78] | 3.25[79] | 1.13[80] | 1.81[81] | 2.01[82] | 1.09[83] | 1.60[84] |
13 | CAV1 | Caveolin-1 | [85] | -6.63[86] | -9.08[87] | -2.95[88] | 1.50[89] | 0.71[90] | -1.45[91] |
14 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [92] | 0.13[93] | -0.41[94] | 0.55[95] | 2.66[96] | 0.95[97] | 1.50[98] |
15 | NFKB2 | Nuclear factor NF-kappa-B p100 subunit | [99] | -0.57[100] | 0.11[101] | 0.42[102] | -1.25[103] | 0.16[104] | -2.47[105] |
16 | JAK1 | Tyrosine-protein kinase JAK1 | [106] | 0.71[107] | 0.58[108] | 0.62[109] | 0.76[110] | 1.96[111] | 2.08[112] |
17 | CD4 | T-cell surface glycoprotein CD4 | [113] | -5.55[114] | -2.99[115] | -5.77[116] | -7.32[117] | -8.82[118] | 0.46[119] |
18 | CYCS | Cytochrome c | [120] | 1.53[121] | 2.11[122] | 2.04[123] | 1.46[124] | 2.42[125] | 1.87[126] |
19 | CASP3 | Caspase-3 | [127] | 0.34[128] | 1.39[129] | -1.30[130] | -0.77[131] | 0.79[132] | -0.26[133] |
20 | ENDOG | Endonuclease G, mitochondrial | [134] | -2.47[135] | -1.84[136] | -2.69[137] | -3.71[138] | -3.00[139] | -2.51[140] |
21 | BID | BH3-interacting domain death agonist | [141] | -0.07[142] | 0.42[143] | -0.11[144] | -0.16[145] | -0.14[146] | 0.72[147] |
22 | JKAMP | JNK1/MAPK8-associated membrane protein | [148] | -0.28[149] | 0.65[150] | -0.01[151] | 0.43[152] | 0.85[153] | 0.29[154] |
23 | MICA | MHC class I polypeptide-related sequence A | [155] | -0.95[156] | 0.19[157] | -3.94[158] | -0.53[159] | 0.07[160] | -2.34[161] |
24 | DFFA | DNA fragmentation factor subunit alpha | [162] | -0.03[163] | 0.70[164] | 0.23[165] | -0.14[166] | 0.45[167] | 0.28[168] |
25 | DAG1 | Dystroglycan | [169] | 2.91[170] | 1.89[171] | 2.15[172] | 2.15[173] | 1.97[174] | 1.83[175] |
26 | MAPK1 | Mitogen-activated protein kinase 1 | [176] | 1.91[177] | 2.43[178] | 2.11[179] | 1.98[180] | 2.19[181] | 2.32[182] |
27 | CD55 | Complement decay-accelerating factor | [183] | -1.08[184] | -1.12[185] | -0.76[186] | -0.55[187] | 1.51[188] | -0.60[189] |
28 | CASP7 | Caspase-7 | [190] | -0.11[191] | -0.09[192] | 0.20[193] | -0.77[194] | 0.00[195] | 0.06[196] |
29 | CXADR | Coxsackievirus and adenovirus receptor | [197] | 0.51[198] | 1.94[199] | -0.16[200] | -0.94[201] | -0.74[202] | 1.97[203] |
30 | CASP8 | Caspase-8 | [204] | 0.22[205] | 1.17[206] | 0.20[207] | 0.05[208] | -0.14[209] | -0.87[210] |
31 | CASP6 | Caspase-6 | [211] | -1.07[212] | -0.48[213] | -0.26[214] | -0.82[215] | -0.59[216] | -0.33[217] |
32 | BNIP2 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 | [218] | -0.36[219] | 0.64[220] | 0.48[221] | 0.87[222] | 1.34[223] | 1.30[224] |
33 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [225] | -0.27[226] | 0.23[227] | 1.17[228] | 2.20[229] | 2.26[230] | 3.55[231] |
34 | SOS1 | Son of sevenless homolog 1 | [232] | 0.10[233] | 2.01[234] | 1.37[235] | 0.97[236] | 0.77[237] | 1.09[238] |
35 | AIF1 | Allograft inflammatory factor 1 | [239] | -6.14[240] | -3.39[241] | -6.19[242] | [243] | [244] | -0.34[245] |
36 | CHRAC1 | Chromatin accessibility complex protein 1 | [246] | 0.60[247] | 1.11[248] | 0.79[249] | 0.33[250] | 0.65[251] | 0.17[252] |
37 | DMD | Dystrophin | [253] | 0.35[254] | 1.17[255] | 1.23[256] | -1.64[257] | -1.03[258] | 3.21[259] |
38 | TICAM1 | TIR domain-containing adapter molecule 1 | [260] | -0.51[261] | -1.23[262] | -0.45[263] | -1.10[264] | 0.51[265] | 0.05[266] |
39 | MAPK3 | Mitogen-activated protein kinase 3 | [267] | 2.05[268] | 2.48[269] | 2.37[270] | 0.55[271] | 1.13[272] | -0.49[273] |
40 | GSK3B | Glycogen synthase kinase-3 beta | [274] | 1.47[275] | 1.48[276] | 1.91[277] | 1.94[278] | 2.33[279] | 1.71[280] |
41 | ABL1 | Tyrosine-protein kinase ABL1 | [281] | 2.43[282] | 2.20[283] | 2.85[284] | 2.20[285] | 3.44[286] | 1.49[287] |
42 | EDN1 | Endothelin-1 | [288] | -0.58[289] | -3.74[290] | 0.25[291] | -0.35[292] | -3.28[293] | -1.49[294] |
43 | RAC2 | Ras-related C3 botulinum toxin substrate 2 | [295] | -1.51[296] | -7.12[297] | -7.88[298] | -1.26[299] | 3.10[300] | -0.68[301] |
44 | SRC | Proto-oncogene tyrosine-protein kinase Src | [302] | 3.23[303] | 3.59[304] | 2.44[305] | 2.53[306] | 2.26[307] | -0.30[308] |
45 | CASP1 | Caspase-1 | [309] | -2.83[310] | -5.85[311] | -4.47[312] | 0.21[313] | 0.92[314] | -0.18[315] |
46 | ITGB2 | Integrin beta-2 | [316] | 1.50[317] | 3.26[318] | -5.17[319] | -5.06[320] | -6.49[321] | 1.86[322] |
47 | SGCB | Beta-sarcoglycan | [323] | 0.86[324] | -0.09[325] | -1.18[326] | 2.55[327] | 3.60[328] | 1.01[329] |
48 | RAC3 | Ras-related C3 botulinum toxin substrate 3 | [330] | -0.17[331] | 3.27[332] | 1.96[333] | 0.24[334] | -0.68[335] | -2.93[336] |
49 | RASA1 | Ras GTPase-activating protein 1 | [337] | 0.58[338] | 1.87[339] | 1.83[340] | 2.04[341] | 1.66[342] | 1.76[343] |
50 | CASP9 | Caspase-9 | [344] | 0.36[345] | 1.70[346] | 0.67[347] | 0.37[348] | 0.25[349] | 0.01[350] |
51 | HLA-DMA | HLA class II histocompatibility antigen, DM alpha chain | [351] | -2.48[352] | -1.98[353] | -2.82[354] | -0.56[355] | -0.94[356] | 0.12[357] |
52 | PYCARD | Apoptosis-associated speck-like protein containing a CARD | [358] | 0.26[359] | 0.83[360] | -8.38[361] | -8.11[362] | 1.02[363] | -0.29[364] |
53 | TGFB1 | Transforming growth factor beta-1 | [365] | 3.67[366] | 3.01[367] | 0.12[368] | 3.97[369] | 3.76[370] | -0.68[371] |
54 | SOCS1 | Suppressor of cytokine signaling 1 | [372] | -1.25[373] | 0.00[374] | 0.12[375] | -1.66[376] | -2.49[377] | -0.92[378] |
55 | FYN | Tyrosine-protein kinase Fyn | [379] | 1.14[380] | -7.08[381] | 1.34[382] | 1.60[383] | 3.69[384] | 1.52[385] |
56 | CXCR4 | C-X-C chemokine receptor type 4 | [386] | -1.66[387] | [388] | -1.89[389] | -5.43[390] | -1.04[391] | 0.48[392] |
57 | CREB1 | Cyclic AMP-responsive element-binding protein 1 | [393] | 1.92[394] | 3.46[395] | 3.80[396] | 2.67[397] | 3.17[398] | 2.89[399] |
58 | CASP2 | Caspase-2 | [400] | 1.90[401] | 1.92[402] | 2.57[403] | 2.00[404] | 2.99[405] | 2.13[406] |
59 | IL6 | Interleukin-6 | [407] | -8.24[408] | [409] | -4.40[410] | -0.73[411] | 2.35[412] | [413] |
60 | ABL2 | Abelson tyrosine-protein kinase 2 | [414] | 2.27[415] | 2.68[416] | 3.47[417] | 4.01[418] | 4.77[419] | 3.47[420] |
61 | TLR3 | Toll-like receptor 3 | [421] | -3.64[422] | -3.72[423] | -4.19[424] | -0.24[425] | 1.40[426] | 1.60[427] |
62 | ITGAL | Integrin alpha-L | [428] | -0.42[429] | 1.81[430] | 3.34[431] | -4.16[432] | -3.51[433] | 2.69[434] |
63 | MMP9 | Matrix metalloproteinase-9 | [435] | -2.52[436] | -3.19[437] | -5.73[438] | -1.30[439] | -3.30[440] | 0.41[441] |
64 | DFFB | DNA fragmentation factor subunit beta | [442] | 1.09[443] | 2.39[444] | 1.60[445] | 0.90[446] | 1.13[447] | 1.18[448] |
65 | NOD2 | Nucleotide-binding oligomerization domain-containing protein 2 | [449] | -1.70[450] | -3.29[451] | [452] | -3.48[453] | 0.63[454] | 0.02[455] |
66 | TLR4 | Toll-like receptor 4 | [456] | 0.47[457] | -4.30[458] | -5.34[459] | -4.97[460] | 6.01[461] | 5.01[462] |
67 | IL10 | Interleukin-10 | [463] | -1.67[464] | -1.54[465] | -1.51[466] | -1.85[467] | -1.76[468] | -1.04[469] |
68 | IFNG | Interferon gamma | [470] | [471] | [472] | [473] | -0.56[474] | [475] | -1.75[476] |
69 | IL12A | Interleukin-12 subunit alpha | [477] | -1.20[478] | [479] | 0.52[480] | -1.42[481] | 0.94[482] | -2.63[483] |
70 | TNF | Tumor necrosis factor | [484] | 1.30[485] | -0.45[486] | -5.20[487] | -2.09[488] | -4.76[489] | -1.34[490] |
71 | TLR5 | Toll-like receptor 5 | [491] | -3.08[492] | -4.76[493] | 0.57[494] | -1.86[495] | -1.16[496] | 3.47[497] |
72 | PTCRA | Pre T-cell antigen receptor alpha | [498] | [499] | -3.74[500] | [501] | -4.45[502] | [503] | -0.62[504] |
73 | BCL2 | Apoptosis regulator Bcl-2 | [505] | -2.65[506] | 3.13[507] | -4.42[508] | 1.90[509] | 2.18[510] | 3.78[511] |
74 | CD40LG | CD40 ligand | [512] | -4.57[513] | [514] | -5.99[515] | -4.11[516] | [517] | -0.03[518] |
75 | CCR5 | C-C chemokine receptor type 5 | [519] | -5.92[520] | [521] | 2.53[522] | -5.90[523] | [524] | 1.11[525] |
76 | NOS1 | Nitric oxide synthase, brain | [526] | -1.35[527] | 1.00[528] | -0.72[529] | -0.54[530] | -0.09[531] | 1.24[532] |
77 | CD80 | T-lymphocyte activation antigen CD80 | [533] | [534] | [535] | -4.83[536] | -1.03[537] | -1.53[538] | 3.17[539] |
78 | SGCA | Alpha-sarcoglycan | [540] | 2.07[541] | [542] | -3.62[543] | -2.32[544] | [545] | 2.95[546] |
79 | SGCD | Delta-sarcoglycan | [547] | -3.54[548] | [549] | -0.28[550] | 3.01[551] | 4.05[552] | 6.58[553] |
80 | LAMA2 | Laminin subunit alpha-2 | [554] | 5.74[555] | 6.02[556] | 3.60[557] | 10.56[558] | 10.88[559] | 13.63[560] |
81 | SGCG | Gamma-sarcoglycan | [561] | [562] | [563] | [564] | [565] | [566] | [567] |
82 | MYH6 | Myosin-6 | [568] | [569] | [570] | [571] | [572] | [573] | [574] |
83 | IL2 | Interleukin-2 | [575] | [576] | [577] | [578] | [579] | [580] | [581] |
84 | IL12B | Interleukin-12 subunit beta | [582] | [583] | [584] | [585] | [586] | [587] | [588] |
85 | CCR3 | C-C chemokine receptor type 3 | [589] | [590] | [591] | [592] | [593] | [594] | [595] |
86 | MIR7705 | [596] | [597] | [598] | [599] | [600] | [601] | [602] | |
87 | CAAP1 | Caspase activity and apoptosis inhibitor 1 | [603] | [604] | [605] | [606] | [607] | [608] | [609] |