WP_ACTIVATION_OF_NLRP3_INFLAMMASOME_BY_SARSCOV2 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RELA Transcription factor p65 [1] -0.15[2] -0.22[3] 0.13[4] -0.10[5] -0.93[6] -0.55[7]
2 NFKB1 Nuclear factor NF-kappa-B p105 subunit [8] 0.39[9] 0.49[10] 0.50[11] -0.29[12] -0.12[13] 0.78[14]
3 CASP1 Caspase-1 [15] -3.32[16] -6.29[17] -4.54[18] 0.04[19] -0.54[20] -0.40[21]
4 IL1B Interleukin-1 beta [22] -8.98[23] -8.42[24] -3.88[25] -3.63[26] 1.22[27] -4.87[28]
5 PYCARD Apoptosis-associated speck-like protein containing a CARD [29] -0.23[30] 0.39[31] -8.46[32] -8.28[33] -0.44[34] -0.50[35]
6 TRAF3 TNF receptor-associated factor 3 [36] 2.61[37] 2.45[38] 2.28[39] 2.79[40] 2.46[41] 2.26[42]
7 NLRP3 NACHT, LRR and PYD domains-containing protein 3 [43] -3.92[44] -1.25[45] -2.84[46] -1.43[47] 0.32[48] 1.92[49]
[1]
ref_hepatocyte RELA
Mean 16
Standard deviation 11
Values 35 8.1 15 9.8 12
[2]
HepG2 RELA
Mean 38.7
Standard deviation 4.7
Values 35 42
[3]
HepG2.C3A RELA
Mean 24.3
Standard deviation 6.4
Values 20 29
[4]
HuH.7 RELA
Mean 25.6
Standard deviation 2.6
Values 23 25 29
[5]
SNU475 RELA
Mean 28.2
Standard deviation 0.33
Values 28 28
[6]
THLE RELA
Mean 29.7
Standard deviation 4
Values 27 32
[7]
liver RELA
Mean 12.3
Standard deviation 8.7
Values 5.7 4.1 19 20
[8]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[9]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[10]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[11]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[12]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[13]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[14]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[15]
ref_hepatocyte CASP1
Mean 3.66
Standard deviation 3.7
Values 0.076 4.9 3.7 0.5 9.1
[16]
HepG2 CASP1
Mean 0.987
Standard deviation 0.74
Values 1.5 0.46
[17]
HepG2.C3A CASP1
Mean 0.0833
Standard deviation 0.049
Values 0.12 0.049
[18]
HuH.7 CASP1
Mean 0.231
Standard deviation 0.041
Values 0.23 0.27 0.19
[19]
SNU475 CASP1
Mean 7.12
Standard deviation 0.23
Values 6.9 7.3
[20]
THLE CASP1
Mean 8.87
Standard deviation 1.2
Values 9.7 8
[21]
liver CASP1
Mean 3.13
Standard deviation 0.99
Values 2 2.6 3.7 4.2
[22]
ref_hepatocyte IL1B
Mean 3.09
Standard deviation 5.4
Values 13 0.76 2 0 0.08
[23]
HepG2 IL1B
Mean 0.0165
Standard deviation 0.017
Values 0.0043 0.029
[24]
HepG2.C3A IL1B
Mean 0.0161
Standard deviation 0.023
Values 0.032 0
[25]
HuH.7 IL1B
Mean 0.309
Standard deviation 0.06
Values 0.3 0.37 0.25
[26]
SNU475 IL1B
Mean 0.472
Standard deviation 0.21
Values 0.62 0.32
[27]
THLE IL1B
Mean 25.4
Standard deviation 8.5
Values 31 19
[28]
liver IL1B
Mean 0.12
Standard deviation 0.051
Values 0.17 0.11 0.14 0.051
[29]
ref_hepatocyte PYCARD
Mean 2.47
Standard deviation 1.8
Values 2.3 5.2 2.7 0.17 2
[30]
HepG2 PYCARD
Mean 5.68
Standard deviation 3.5
Values 3.2 8.1
[31]
HepG2.C3A PYCARD
Mean 5.76
Standard deviation 0.0033
Values 5.8 5.8
[32]
HuH.7 PYCARD
Mean 0.0103
Standard deviation 0.013
Values 0 0.0064 0.025
[33]
SNU475 PYCARD
Mean 0.015
Standard deviation 0.015
Values 0.025 0.0046
[34]
THLE PYCARD
Mean 6.42
Standard deviation 0.22
Values 6.3 6.6
[35]
liver PYCARD
Mean 1.97
Standard deviation 1.2
Values 0.99 0.9 3.3 2.7
[36]
ref_hepatocyte TRAF3
Mean 1.27
Standard deviation 0.83
Values 1.7 0.6 0.56 0.98 2.5
[37]
HepG2 TRAF3
Mean 20.8
Standard deviation 3.9
Values 18 24
[38]
HepG2.C3A TRAF3
Mean 12.4
Standard deviation 0.058
Values 12 12
[39]
HuH.7 TRAF3
Mean 9.05
Standard deviation 1.3
Values 7.9 8.7 10
[40]
SNU475 TRAF3
Mean 16.6
Standard deviation 0.54
Values 16 17
[41]
THLE TRAF3
Mean 24.7
Standard deviation 3.8
Values 22 27
[42]
liver TRAF3
Mean 6.87
Standard deviation 4
Values 11 9.3 4.4 2.6
[43]
ref_hepatocyte NLRP3
Mean 0.117
Standard deviation 0.12
Values 0 0.19 0.28 0 0.11
[44]
HepG2 NLRP3
Mean 0.0207
Standard deviation 0.013
Values 0.03 0.011
[45]
HepG2.C3A NLRP3
Mean 0.0871
Standard deviation 0.013
Values 0.097 0.078
[46]
HuH.7 NLRP3
Mean 0.024
Standard deviation 0.036
Values 0.066 0.0064 0
[47]
SNU475 NLRP3
Mean 0.0819
Standard deviation 0.063
Values 0.13 0.037
[48]
THLE NLRP3
Mean 0.513
Standard deviation 0.15
Values 0.62 0.4
[49]
liver NLRP3
Mean 0.499
Standard deviation 0.28
Values 0.58 0.84 0.19 0.39