WP_ACE_INHIBITOR_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AGT Angiotensinogen [1] 0.50[2] 0.83[3] -0.18[4] -3.24[5] -8.38[6] 0.65[7]
2 KNG1 Kininogen-1 [8] -5.28[9] -6.44[10] -0.22[11] -9.52[12] -8.76[13] -1.29[14]
3 ATP6AP2 Renin receptor [15] 1.69[16] 0.83[17] 1.85[18] 3.67[19] 4.49[20] -1.19[21]
4 AGTR1 Type-1 angiotensin II receptor [22] -5.02[23] -3.81[24] 2.28[25] 2.10[26] -2.38[27] 0.24[28]
5 TGFB1 Transforming growth factor beta-1 [29] 5.80[30] 4.14[31] 1.97[32] 7.20[33] 6.36[34] -2.43[35]
6 NR3C2 Mineralocorticoid receptor [36] -1.20[37] -0.54[38] 0.79[39] -1.92[40] 2.06[41] 1.82[42]
7 CTSG Cathepsin G [43] [44] [45] [46] [47] [48] -3.36[49]
8 ACE Angiotensin-converting enzyme [50] -2.43[51] -5.55[52] -2.45[53] 1.36[54] 0.44[55] 0.98[56]
9 ACE2 Angiotensin-converting enzyme 2 [57] 2.02[58] 2.73[59] 2.34[60] -3.65[61] -3.13[62] -1.27[63]
10 CMA1 Chymase [64] -2.51[65] -4.92[66] [67] -4.37[68] [69] -3.56[70]
11 REN Renin [71] -0.61[72] [73] [74] 1.51[75] [76] -3.04[77]
12 NOS3 Nitric oxide synthase, endothelial [78] 7.10[79] 3.58[80] 3.62[81] 3.42[82] 4.68[83] 1.57[84]
13 BDKRB2 B2 bradykinin receptor [85] 4.73[86] -1.04[87] 0.51[88] 12.01[89] 9.95[90] 1.93[91]
14 AGTR2 Type-2 angiotensin II receptor [92] [93] [94] [95] [96] [97] [98]
15 MAS1 Proto-oncogene Mas [99] [100] [101] [102] [103] [104] [105]
16 BDKRB1 B1 bradykinin receptor [106] [107] [108] [109] [110] [111] [112]
17 CYP11B2 Cytochrome P450 11B2, mitochondrial [113] [114] [115] [116] [117] [118] [119]
[1]
ref_hepatocyte AGT
Mean 439
Standard deviation 4.5e+02
Values 77 7e+02 1.1e+03 3.3e+02 6.7
[2]
HepG2 AGT
Mean 273
Standard deviation 17
Values 2.9e+02 2.6e+02
[3]
HepG2.C3A AGT
Mean 471
Standard deviation 99
Values 4e+02 5.4e+02
[4]
HuH.7 AGT
Mean 150
Standard deviation 28
Values 1.4e+02 1.8e+02 1.3e+02
[5]
SNU475 AGT
Mean 8.25
Standard deviation 2.2
Values 9.8 6.7
[6]
THLE AGT
Mean 0.276
Standard deviation 0.11
Values 0.35 0.2
[7]
liver AGT
Mean 2.25e+03
Standard deviation 2.3e+03
Values 6.1e+02 6.9e+02 5.5e+03 2.2e+03
[8]
ref_hepatocyte KNG1
Mean 402
Standard deviation 5.4e+02
Values 56 1.2e+03 7.5e+02 13 3.1
[9]
HepG2 KNG1
Mean 4.56
Standard deviation 1.2
Values 5.4 3.7
[10]
HepG2.C3A KNG1
Mean 2.8
Standard deviation 1.5
Values 1.7 3.9
[11]
HuH.7 KNG1
Mean 134
Standard deviation 1.2e+02
Values 69 2.7e+02 61
[12]
SNU475 KNG1
Mean 0.0979
Standard deviation 0.045
Values 0.066 0.13
[13]
THLE KNG1
Mean 0.194
Standard deviation 0.026
Values 0.21 0.18
[14]
liver KNG1
Mean 537
Standard deviation 95
Values 4.1e+02 5.5e+02 6.4e+02 5.5e+02
[15]
ref_hepatocyte ATP6AP2
Mean 27.6
Standard deviation 12
Values 8.8 31 27 30 41
[16]
HepG2 ATP6AP2
Mean 39.1
Standard deviation 6
Values 43 35
[17]
HepG2.C3A ATP6AP2
Mean 29.7
Standard deviation 1.8
Values 31 28
[18]
HuH.7 ATP6AP2
Mean 38.4
Standard deviation 4.6
Values 44 36 36
[19]
SNU475 ATP6AP2
Mean 62.4
Standard deviation 9.8
Values 55 69
[20]
THLE ATP6AP2
Mean 130
Standard deviation 21
Values 1.2e+02 1.4e+02
[21]
liver ATP6AP2
Mean 39.5
Standard deviation 21
Values 19 25 52 62
[22]
ref_hepatocyte AGTR1
Mean 6.51
Standard deviation 7
Values 1.6 11 17 1.1 2
[23]
HepG2 AGTR1
Mean 0.088
Standard deviation 0.0029
Values 0.09 0.086
[24]
HepG2.C3A AGTR1
Mean 0.28
Standard deviation 0.17
Values 0.16 0.4
[25]
HuH.7 AGTR1
Mean 12.2
Standard deviation 6.8
Values 9.2 20 7.4
[26]
SNU475 AGTR1
Mean 4.95
Standard deviation 0.26
Values 4.8 5.1
[27]
THLE AGTR1
Mean 0.263
Standard deviation 0.079
Values 0.21 0.32
[28]
liver AGTR1
Mean 24.9
Standard deviation 11
Values 18 15 39 28
[29]
ref_hepatocyte TGFB1
Mean 2.22
Standard deviation 1.8
Values 0.92 2.3 1.3 5.3 1.3
[30]
HepG2 TGFB1
Mean 54.4
Standard deviation 32
Values 32 77
[31]
HepG2.C3A TGFB1
Mean 23.6
Standard deviation 8.3
Values 18 29
[32]
HuH.7 TGFB1
Mean 3.37
Standard deviation 1.4
Values 3.7 1.8 4.5
[33]
SNU475 TGFB1
Mean 58.3
Standard deviation 7.8
Values 53 64
[34]
THLE TGFB1
Mean 38.3
Standard deviation 9.8
Values 31 45
[35]
liver TGFB1
Mean 1.34
Standard deviation 0.71
Values 2.3 1.4 1.1 0.62
[36]
ref_hepatocyte NR3C2
Mean 0.733
Standard deviation 0.58
Values 0.6 1.5 1.1 0 0.48
[37]
HepG2 NR3C2
Mean 0.14
Standard deviation 0.044
Values 0.17 0.11
[38]
HepG2.C3A NR3C2
Mean 0.305
Standard deviation 0.037
Values 0.28 0.33
[39]
HuH.7 NR3C2
Mean 0.49
Standard deviation 0.41
Values 0.25 0.96 0.25
[40]
SNU475 NR3C2
Mean 0.0346
Standard deviation 0.023
Values 0.051 0.019
[41]
THLE NR3C2
Mean 0.643
Standard deviation 0.11
Values 0.56 0.72
[42]
liver NR3C2
Mean 8.43
Standard deviation 2.8
Values 11 8.8 9.7 4.4
[43]
ref_hepatocyte CTSG
Mean 0.731
Standard deviation 1.1
Values 0 2.4 1.2 0 0
[44]
HepG2 CTSG
Mean 0
Standard deviation 0
Values 0 0
[45]
HepG2.C3A CTSG
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 CTSG
Mean 0
Standard deviation 0
Values 0 0 0
[47]
SNU475 CTSG
Mean 0
Standard deviation 0
Values 0 0
[48]
THLE CTSG
Mean 0
Standard deviation 0
Values 0 0
[49]
liver CTSG
Mean 0.232
Standard deviation 0.29
Values 0 0.21 0.071 0.64
[50]
ref_hepatocyte ACE
Mean 0.377
Standard deviation 0.39
Values 0.66 0.31 0.9 0 0.023
[51]
HepG2 ACE
Mean 0.0308
Standard deviation 0.037
Values 0.0043 0.057
[52]
HepG2.C3A ACE
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[53]
HuH.7 ACE
Mean 0.0267
Standard deviation 0.016
Values 0.019 0.045 0.016
[54]
SNU475 ACE
Mean 0.172
Standard deviation 0.014
Values 0.18 0.16
[55]
THLE ACE
Mean 0.107
Standard deviation 0.024
Values 0.12 0.09
[56]
liver ACE
Mean 2.42
Standard deviation 0.61
Values 2.7 3.1 1.7 2.2
[57]
ref_hepatocyte ACE2
Mean 0.357
Standard deviation 0.39
Values 0 0.41 0.21 0.17 1
[58]
HepG2 ACE2
Mean 0.635
Standard deviation 0.46
Values 0.96 0.31
[59]
HepG2.C3A ACE2
Mean 1.43
Standard deviation 0.89
Values 2.1 0.81
[60]
HuH.7 ACE2
Mean 0.702
Standard deviation 0.38
Values 0.47 1.1 0.5
[61]
SNU475 ACE2
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[62]
THLE ACE2
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[63]
liver ACE2
Mean 0.481
Standard deviation 0.28
Values 0.34 0.9 0.4 0.28
[64]
ref_hepatocyte CMA1
Mean 0.269
Standard deviation 0.51
Values 0 1.2 0.18 0 0
[65]
HepG2 CMA1
Mean 0.0207
Standard deviation 0.013
Values 0.03 0.011
[66]
HepG2.C3A CMA1
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[67]
HuH.7 CMA1
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 CMA1
Mean 0.00232
Standard deviation 0.0033
Values 0 0.0046
[69]
THLE CMA1
Mean 0
Standard deviation 0
Values 0 0
[70]
liver CMA1
Mean 0.0741
Standard deviation 0.051
Values 0.079 0.11 0 0.1
[71]
ref_hepatocyte REN
Mean 0.266
Standard deviation 0.46
Values 1.1 0.16 0.095 0 0
[72]
HepG2 REN
Mean 0.0766
Standard deviation 0.029
Values 0.056 0.097
[73]
HepG2.C3A REN
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 REN
Mean 0
Standard deviation 0
Values 0 0 0
[75]
SNU475 REN
Mean 0.135
Standard deviation 0.12
Values 0.22 0.046
[76]
THLE REN
Mean 0
Standard deviation 0
Values 0 0
[77]
liver REN
Mean 0.105
Standard deviation 0.13
Values 0.28 0.14 0 0
[78]
ref_hepatocyte NOS3
Mean 0.251
Standard deviation 0.22
Values 0.014 0.18 0.12 0.58 0.37
[79]
HepG2 NOS3
Mean 15.1
Standard deviation 1.3
Values 16 14
[80]
HepG2.C3A NOS3
Mean 1.81
Standard deviation 0.061
Values 1.9 1.8
[81]
HuH.7 NOS3
Mean 1.2
Standard deviation 0.2
Values 1.2 1 1.4
[82]
SNU475 NOS3
Mean 0.48
Standard deviation 0.28
Values 0.28 0.68
[83]
THLE NOS3
Mean 1.36
Standard deviation 0.21
Values 1.5 1.2
[84]
liver NOS3
Mean 2.44
Standard deviation 1.3
Values 4.3 2.3 1.5 1.6
[85]
ref_hepatocyte BDKRB2
Mean 0.0166
Standard deviation 0.037
Values 0 0 0 0 0.083
[86]
HepG2 BDKRB2
Mean 0.193
Standard deviation 0.21
Values 0.043 0.34
[87]
HepG2.C3A BDKRB2
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[88]
HuH.7 BDKRB2
Mean 0.00915
Standard deviation 0.0097
Values 0 0.019 0.0082
[89]
SNU475 BDKRB2
Mean 12.2
Standard deviation 3
Values 10 14
[90]
THLE BDKRB2
Mean 3.45
Standard deviation 1.1
Values 4.2 2.7
[91]
liver BDKRB2
Mean 0.206
Standard deviation 0.061
Values 0.28 0.13 0.21 0.21
[92]
ref_hepatocyte AGTR2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 AGTR2
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A AGTR2
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 AGTR2
Mean 0.0783
Standard deviation 0.054
Values 0.1 0.12 0.016
[96]
SNU475 AGTR2
Mean 0
Standard deviation 0
Values 0 0
[97]
THLE AGTR2
Mean 0
Standard deviation 0
Values 0 0
[98]
liver AGTR2
Mean 0
Standard deviation 0
Values 0 0 0 0
[99]
ref_hepatocyte MAS1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 MAS1
Missing
[101]
HepG2.C3A MAS1
Missing
[102]
HuH.7 MAS1
Missing
[103]
SNU475 MAS1
Missing
[104]
THLE MAS1
Missing
[105]
liver MAS1
Missing
[106]
ref_hepatocyte BDKRB1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[107]
HepG2 BDKRB1
Mean 0.00501
Standard deviation 0.001
Values 0.0043 0.0057
[108]
HepG2.C3A BDKRB1
Mean 0.0146
Standard deviation 0.021
Values 0 0.029
[109]
HuH.7 BDKRB1
Mean 0.0103
Standard deviation 0.013
Values 0 0.0064 0.025
[110]
SNU475 BDKRB1
Mean 9.81
Standard deviation 2.3
Values 11 8.2
[111]
THLE BDKRB1
Mean 10.5
Standard deviation 1.5
Values 9.4 12
[112]
liver BDKRB1
Mean 0.0173
Standard deviation 0.021
Values 0.026 0.043 0 0
[113]
ref_hepatocyte CYP11B2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 CYP11B2
Missing
[115]
HepG2.C3A CYP11B2
Missing
[116]
HuH.7 CYP11B2
Missing
[117]
SNU475 CYP11B2
Missing
[118]
THLE CYP11B2
Missing
[119]
liver CYP11B2
Missing