WP_16P112_PROXIMAL_DELETION_SYNDROME | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CCT7 | T-complex protein 1 subunit eta | [1] | -0.65[2] | -0.71[3] | -0.91[4] | -1.20[5] | -1.00[6] | -1.21[7] |
2 | ALDOA | Fructose-bisphosphate aldolase A | [8] | 1.60[9] | 1.29[10] | 0.59[11] | 0.92[12] | 0.57[13] | -0.62[14] |
3 | MSN | Moesin | [15] | -8.69[16] | -10.93[17] | -9.37[18] | 0.76[19] | -0.13[20] | -0.72[21] |
4 | CCT3 | T-complex protein 1 subunit gamma | [22] | -0.02[23] | -0.18[24] | -0.11[25] | 0.26[26] | -0.01[27] | -0.44[28] |
5 | CCT8 | T-complex protein 1 subunit theta | [29] | -0.95[30] | -0.29[31] | 0.21[32] | -0.37[33] | -0.18[34] | -0.93[35] |
6 | CCT2 | T-complex protein 1 subunit beta | [36] | -0.64[37] | -0.20[38] | -0.08[39] | -0.33[40] | -0.17[41] | -0.85[42] |
7 | TCP1 | T-complex protein 1 subunit alpha | [43] | -0.14[44] | 0.06[45] | 0.28[46] | -0.48[47] | 0.26[48] | -0.38[49] |
8 | CCT5 | T-complex protein 1 subunit epsilon | [50] | -0.01[51] | -0.16[52] | 0.00[53] | 0.14[54] | 1.09[55] | -0.18[56] |
9 | QPRT | Nicotinate-nucleotide pyrophosphorylase [carboxylating] | [57] | -0.15[58] | -0.01[59] | 0.01[60] | -1.59[61] | -3.19[62] | 0.10[63] |
10 | CCT6A | T-complex protein 1 subunit zeta | [64] | -0.18[65] | 0.25[66] | 0.73[67] | 0.21[68] | 0.11[69] | -0.46[70] |
11 | CCT4 | T-complex protein 1 subunit delta | [71] | 0.11[72] | 0.43[73] | 0.75[74] | 0.29[75] | 0.01[76] | -0.86[77] |
12 | PPP4C | Serine/threonine-protein phosphatase 4 catalytic subunit | [78] | -0.86[79] | -0.58[80] | -0.86[81] | -2.05[82] | -1.91[83] | -0.89[84] |
13 | PCNA | Proliferating cell nuclear antigen | [85] | 0.28[86] | 0.33[87] | -0.83[88] | -0.46[89] | -0.07[90] | -2.51[91] |
14 | TMEM219 | Insulin-like growth factor-binding protein 3 receptor | [92] | -1.64[93] | -1.29[94] | -1.60[95] | -2.49[96] | -2.59[97] | -0.98[98] |
15 | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3 | [99] | -1.83[100] | -1.46[101] | -2.31[102] | -2.07[103] | -2.10[104] | -0.87[105] |
16 | EZR | Ezrin | [106] | 0.36[107] | -0.94[108] | 0.08[109] | -0.58[110] | 0.77[111] | 0.18[112] |
17 | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isofor | 0.19[113] | 0.08[114] | 0.26[115] | 0.97[116] | 0.40[117] | 0.71[118] | |
18 | PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | -0.33[119] | -0.18[120] | -0.56[121] | 0.50[122] | 0.72[123] | 0.46[124] | |
19 | PPP2CB | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | -1.00[125] | -1.28[126] | -0.94[127] | -0.70[128] | -0.69[129] | -0.42[130] | |
20 | MVP | Major vault protein | [131] | -0.20[132] | -1.02[133] | -1.66[134] | 0.19[135] | -0.17[136] | 0.82[137] |
21 | MAZ | Myc-associated zinc finger protein | [138] | 0.66[139] | 0.64[140] | 0.66[141] | -0.22[142] | -0.26[143] | -1.08[144] |
22 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | [145] | -0.46[146] | -0.49[147] | -0.27[148] | -0.98[149] | -0.34[150] | 0.56[151] |
23 | PPP4R2 | Serine/threonine-protein phosphatase 4 regulatory subunit 2 | [152] | -1.73[153] | -0.57[154] | -1.22[155] | -1.66[156] | -0.73[157] | -0.23[158] |
24 | IGBP1 | Immunoglobulin-binding protein 1 | [159] | -0.55[160] | -0.30[161] | 0.40[162] | -0.72[163] | -0.97[164] | -1.47[165] |
25 | HDAC3 | Histone deacetylase 3 | [166] | -0.12[167] | -0.01[168] | 0.05[169] | -0.29[170] | -0.03[171] | 0.16[172] |
26 | INO80E | INO80 complex subunit E | [173] | -1.32[174] | -1.37[175] | -1.26[176] | -2.18[177] | -1.59[178] | -2.37[179] |
27 | KIF22 | Kinesin-like protein KIF22 | [180] | 0.26[181] | 0.78[182] | 1.41[183] | -0.58[184] | 0.29[185] | 0.35[186] |
28 | CASP8 | Caspase-8 | [187] | -0.59[188] | 0.05[189] | -0.53[190] | -0.32[191] | -0.96[192] | -0.86[193] |
29 | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform | 0.64[194] | 0.47[195] | 0.28[196] | 1.05[197] | 1.04[198] | 0.30[199] | |
30 | NR3C1 | Glucocorticoid receptor | [200] | -0.57[201] | -0.93[202] | -0.38[203] | 1.23[204] | 1.46[205] | 2.33[206] |
31 | SIAH1 | E3 ubiquitin-protein ligase SIAH1 | [207] | -2.42[208] | -1.88[209] | -1.62[210] | -2.34[211] | -2.16[212] | -0.44[213] |
32 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protei | -1.15[214] | 0.31[215] | 0.76[216] | -0.80[217] | 0.55[218] | 3.04[219] | |
33 | YPEL3 | Protein yippee-like 3 | [220] | -1.58[221] | -0.78[222] | -1.41[223] | -2.60[224] | -1.71[225] | -0.31[226] |
34 | PARP4 | Poly [ADP-ribose] polymerase 4 | [227] | 0.73[228] | 1.20[229] | -0.01[230] | 2.06[231] | 1.81[232] | 2.37[233] |
35 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [234] | 0.06[235] | -0.19[236] | -0.15[237] | -0.49[238] | 0.53[239] | 1.01[240] |
36 | PPP4R1 | Serine/threonine-protein phosphatase 4 regulatory subunit 1 | [241] | 0.76[242] | 1.21[243] | 1.91[244] | 1.71[245] | 1.32[246] | 1.72[247] |
37 | HIRA | Protein HIRA | [248] | 0.90[249] | 1.39[250] | 1.61[251] | 0.26[252] | 0.76[253] | 1.32[254] |
38 | TP53 | Cellular tumor antigen p53 | [255] | 1.03[256] | 0.66[257] | 1.67[258] | 1.05[259] | 0.82[260] | 0.52[261] |
39 | TRAF2 | TNF receptor-associated factor 2 | [262] | -0.38[263] | -0.25[264] | -0.26[265] | -0.12[266] | 0.00[267] | -0.23[268] |
40 | CCDC6 | Coiled-coil domain-containing protein 6 | [269] | 0.60[270] | 1.35[271] | 0.72[272] | 1.14[273] | 1.61[274] | 1.55[275] |
41 | MAPK3 | Mitogen-activated protein kinase 3 | [276] | 1.24[277] | 1.35[278] | 1.65[279] | 0.18[280] | 0.31[281] | -0.48[282] |
42 | SEZ6L2 | Seizure 6-like protein 2 | [283] | 1.91[284] | 1.75[285] | 2.16[286] | 0.53[287] | 0.69[288] | -3.75[289] |
43 | IGFBP3 | Insulin-like growth factor-binding protein 3 | [290] | 2.44[291] | -2.38[292] | -2.66[293] | 0.21[294] | -0.67[295] | 4.79[296] |
44 | PPARG | Peroxisome proliferator-activated receptor gamma | [297] | -0.69[298] | 0.98[299] | 1.75[300] | 0.61[301] | 0.68[302] | 0.18[303] |
45 | HIRIP3 | HIRA-interacting protein 3 | [304] | -0.01[305] | 0.27[306] | 0.38[307] | -0.67[308] | 0.19[309] | 0.04[310] |
46 | TAOK2 | Serine/threonine-protein kinase TAO2 | [311] | 1.91[312] | 1.89[313] | 1.96[314] | 1.35[315] | 1.59[316] | 1.96[317] |
47 | UNC13B | Protein unc-13 homolog B | [318] | 1.16[319] | 1.34[320] | 2.25[321] | 0.13[322] | 0.84[323] | 3.13[324] |
48 | ZG16 | Zymogen granule membrane protein 16 | [325] | -5.81[326] | -5.71[327] | 0.11[328] | -7.86[329] | -7.33[330] | -0.33[331] |
49 | PPP4R4 | Serine/threonine-protein phosphatase 4 regulatory subunit 4 | [332] | -2.23[333] | -1.26[334] | -2.35[335] | -5.48[336] | 0.74[337] | -0.15[338] |
50 | BPTF | Nucleosome-remodeling factor subunit BPTF | [339] | 1.31[340] | 2.06[341] | 2.67[342] | 2.02[343] | 1.94[344] | 3.75[345] |
51 | CORO1A | Coronin-1A | [346] | -0.05[347] | -0.40[348] | -1.52[349] | -2.76[350] | -1.95[351] | 0.74[352] |
52 | GDPD3 | Lysophospholipase D GDPD3 | [353] | 0.02[354] | 0.73[355] | -2.97[356] | -3.94[357] | -4.07[358] | -4.13[359] |
53 | PAXIP1 | PAX-interacting protein 1 | [360] | 0.34[361] | 0.47[362] | 1.20[363] | 0.30[364] | 0.58[365] | 0.85[366] |
54 | KCTD13 | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein | -0.55[367] | -0.03[368] | -0.88[369] | -1.36[370] | -1.50[371] | -0.30[372] | |
55 | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 | [373] | -0.32[374] | -3.46[375] | 1.64[376] | 0.77[377] | -3.16[378] | -1.06[379] |
56 | ESR1 | Estrogen receptor | [380] | -7.91[381] | [382] | -6.08[383] | -4.41[384] | -6.56[385] | 2.96[386] |
57 | TRAF6 | TNF receptor-associated factor 6 | [387] | 0.48[388] | 0.44[389] | 1.26[390] | 1.42[391] | 0.98[392] | 3.47[393] |
58 | SPN | Leukosialin | [394] | 1.42[395] | -0.38[396] | -0.94[397] | -1.61[398] | -1.67[399] | 0.66[400] |
59 | ASPHD1 | Aspartate beta-hydroxylase domain-containing protein 1 | [401] | 3.08[402] | 3.27[403] | 1.63[404] | 1.65[405] | 3.16[406] | -4.09[407] |
60 | CCT6B | T-complex protein 1 subunit zeta-2 | [408] | -3.11[409] | -2.02[410] | 0.19[411] | -0.86[412] | -2.61[413] | 0.78[414] |
61 | REL | Proto-oncogene c-Rel | [415] | -1.12[416] | 0.71[417] | 0.89[418] | -0.09[419] | 0.17[420] | 2.91[421] |
62 | C16orf54 | Transmembrane protein C16orf54 | [422] | -7.30[423] | -3.48[424] | -0.30[425] | [426] | -5.26[427] | 2.87[428] |
63 | TBX6 | T-box transcription factor TBX6 | [429] | 0.78[430] | 1.92[431] | 2.69[432] | -0.80[433] | -0.36[434] | -0.25[435] |
64 | UNC13A | Protein unc-13 homolog A | [436] | 2.52[437] | 1.68[438] | -0.70[439] | -1.64[440] | 1.36[441] | -0.29[442] |
65 | PRRT2 | Proline-rich transmembrane protein 2 | [443] | 3.09[444] | 4.77[445] | 4.04[446] | 3.86[447] | 3.30[448] | 5.37[449] |
66 | DOC2A | Double C2-like domain-containing protein alpha | [450] | 0.77[451] | -1.50[452] | 4.17[453] | -0.87[454] | 2.89[455] | 1.37[456] |
67 | KMT2D | Histone-lysine N-methyltransferase 2D | [457] | [458] | [459] | [460] | [461] | [462] | [463] |
68 | PPP4R3B | Serine/threonine-protein phosphatase 4 regulatory subunit 3B | [464] | [465] | [466] | [467] | [468] | [469] | [470] |
69 | TLCD3B | [471] | [472] | [473] | [474] | [475] | [476] | [477] | |
70 | KMT2C | Histone-lysine N-methyltransferase 2C | [478] | [479] | [480] | [481] | [482] | [483] | [484] |
71 | CDIPTOSP | [485] | [486] | [487] | [488] | [489] | [490] | [491] | |
72 | MIR3680-2 | [492] | [493] | [494] | [495] | [496] | [497] | [498] | |
73 | C16orf92 | Uncharacterized protein C16orf92 | [499] | [500] | [501] | [502] | [503] | [504] | [505] |
74 | PAGR1 | PAXIP1-associated glutamate-rich protein 1 | [506] | [507] | [508] | [509] | [510] | [511] | [512] |
75 | PPP4R3A | Serine/threonine-protein phosphatase 4 regulatory subunit 3A | [513] | [514] | [515] | [516] | [517] | [518] | [519] |
76 | MIR3680-1 | [520] | [521] | [522] | [523] | [524] | [525] | [526] |