REACTOME_PLASMA_LIPOPROTEIN_REMODELING | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | ALB | Serum albumin | [1] | 0.04[2] | 0.90[3] | 0.49[4] | -4.72[5] | -4.95[6] | 0.39[7] |
2 | APOA2 | Apolipoprotein A-II | [8] | -0.93[9] | -1.65[10] | -1.15[11] | -6.21[12] | -6.39[13] | -1.61[14] |
3 | APOA1 | Apolipoprotein A-I | [15] | -0.91[16] | -1.40[17] | -2.51[18] | -6.72[19] | -7.29[20] | -0.64[21] |
4 | APOC3 | Apolipoprotein C-III | [22] | -4.77[23] | -3.86[24] | -3.95[25] | -9.34[26] | -10.37[27] | -1.13[28] |
5 | APOE | Apolipoprotein E | [29] | -0.33[30] | -1.72[31] | -0.22[32] | -3.44[33] | -3.08[34] | -1.32[35] |
6 | APOC2 | Apolipoprotein C-II | [36] | [37] | [38] | [39] | [40] | [41] | [42] |
7 | P4HB | Protein disulfide-isomerase | [43] | 3.36[44] | 1.42[45] | 2.27[46] | 5.77[47] | 5.49[48] | 1.06[49] |
8 | APOB | Apolipoprotein B-100 | [50] | 5.27[51] | 4.27[52] | 4.97[53] | -0.11[54] | -0.45[55] | 5.38[56] |
9 | CREB3L3 | Cyclic AMP-responsive element-binding protein 3-like protein 3 | [57] | -1.85[58] | -1.71[59] | 1.32[60] | -2.54[61] | -1.66[62] | 0.39[63] |
10 | ANGPTL3 | Angiopoietin-related protein 3 | [64] | -7.35[65] | -5.25[66] | 0.74[67] | -4.81[68] | -4.90[69] | 0.69[70] |
11 | APOF | Apolipoprotein F | [71] | -2.69[72] | -1.88[73] | -6.75[74] | -5.95[75] | -7.51[76] | 0.35[77] |
12 | APOA5 | Apolipoprotein A-V | [78] | 0.68[79] | 0.62[80] | -0.01[81] | -4.92[82] | -4.05[83] | 2.69[84] |
13 | LCAT | Phosphatidylcholine-sterol acyltransferase | [85] | -0.70[86] | -0.33[87] | -2.30[88] | 0.78[89] | 1.97[90] | 0.02[91] |
14 | LIPC | Hepatic triacylglycerol lipase | [92] | 1.14[93] | -0.50[94] | 3.01[95] | -2.05[96] | -3.01[97] | 0.20[98] |
15 | FURIN | Furin | [99] | 4.95[100] | -0.56[101] | 3.12[102] | 6.07[103] | 6.12[104] | 2.17[105] |
16 | APOA4 | Apolipoprotein A-IV | [106] | 0.68[107] | 0.66[108] | -3.82[109] | -5.34[110] | -7.19[111] | 1.81[112] |
17 | PCSK6 | Proprotein convertase subtilisin/kexin type 6 | [113] | 3.61[114] | 1.68[115] | 2.49[116] | 0.55[117] | -0.19[118] | 2.97[119] |
18 | MTTP | Microsomal triglyceride transfer protein large subunit | [120] | 1.19[121] | 2.70[122] | 5.20[123] | -0.05[124] | 0.44[125] | 2.36[126] |
19 | LPA | Apolipoprotein(a) | [127] | [128] | -9.55[129] | -0.98[130] | -4.78[131] | -4.74[132] | 0.79[133] |
20 | ANGPTL4 | Angiopoietin-related protein 4 | [134] | 1.61[135] | -1.12[136] | 0.86[137] | 4.38[138] | 7.94[139] | 0.99[140] |
21 | MBTPS1 | Membrane-bound transcription factor site-1 protease | [141] | 4.91[142] | 2.96[143] | 4.47[144] | 8.72[145] | 8.37[146] | 1.83[147] |
22 | LIPG | Endothelial lipase | [148] | -2.53[149] | -4.22[150] | 1.61[151] | 2.75[152] | 0.84[153] | 2.74[154] |
23 | FGF21 | Fibroblast growth factor 21 | [155] | -5.39[156] | -9.15[157] | -4.02[158] | -1.92[159] | -2.80[160] | -1.70[161] |
24 | LMF2 | Lipase maturation factor 2 | [162] | 4.19[163] | 2.05[164] | 4.29[165] | 7.19[166] | 7.31[167] | 0.81[168] |
25 | PLTP | Phospholipid transfer protein | [169] | 4.83[170] | 2.91[171] | 5.81[172] | 3.92[173] | 8.29[174] | 2.14[175] |
26 | CIDEC | Cell death activator CIDE-3 | [176] | 2.01[177] | 2.97[178] | 2.42[179] | 1.53[180] | 0.75[181] | -2.21[182] |
27 | MBTPS2 | Membrane-bound transcription factor site-2 protease | [183] | 4.27[184] | 2.86[185] | 5.17[186] | 9.43[187] | 8.93[188] | 2.07[189] |
28 | LMF1 | Lipase maturation factor 1 | [190] | 2.46[191] | 0.81[192] | 3.48[193] | 3.14[194] | 3.79[195] | 1.45[196] |
29 | CETP | Cholesteryl ester transfer protein | [197] | 2.41[198] | 1.26[199] | -5.66[200] | 7.43[201] | 1.11[202] | 0.32[203] |
30 | ABCG1 | ATP-binding cassette sub-family G member 1 | [204] | 2.32[205] | -5.40[206] | 1.80[207] | 1.85[208] | 6.53[209] | 2.43[210] |
31 | PCSK5 | Proprotein convertase subtilisin/kexin type 5 | [211] | 3.00[212] | -1.93[213] | 5.89[214] | 7.99[215] | 9.20[216] | 1.75[217] |
32 | LPL | Lipoprotein lipase | [218] | [219] | [220] | -4.33[221] | 7.90[222] | 3.86[223] | 0.28[224] |
33 | GPIHBP1 | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 | [225] | -0.73[226] | [227] | 4.08[228] | 3.71[229] | 5.68[230] | |
34 | ANGPTL8 | Angiopoietin-like protein 8 | [231] | [232] | [233] | [234] | [235] | [236] | [237] |