REACTOME_PI_3K_CASCADE_FGFR2 | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | [1] | -0.12[2] | 0.08[3] | -0.22[4] | -0.22[5] | 0.18[6] | -0.33[7] |
2 | GRB2 | Growth factor receptor-bound protein 2 | [8] | 0.63[9] | 0.24[10] | 0.10[11] | -0.56[12] | -0.87[13] | -1.29[14] |
3 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [15] | -1.04[16] | -1.15[17] | -0.32[18] | 0.96[19] | 0.23[20] | 1.42[21] |
4 | FGF2 | Fibroblast growth factor 2 | [22] | -7.26[23] | -7.23[24] | -3.33[25] | -0.18[26] | 1.18[27] | -3.25[28] |
5 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -0.95[29] | 0.46[30] | 0.39[31] | 0.02[32] | -0.01[33] | 0.33[34] | |
6 | FGFR2 | Fibroblast growth factor receptor 2 | [35] | -3.08[36] | -2.10[37] | 1.59[38] | 0.35[39] | -4.72[40] | 1.84[41] |
7 | FRS2 | Fibroblast growth factor receptor substrate 2 | [42] | 0.72[43] | 1.59[44] | 1.83[45] | 1.79[46] | 1.19[47] | 1.76[48] |
8 | GAB1 | GRB2-associated-binding protein 1 | [49] | 0.73[50] | 1.60[51] | 1.46[52] | 0.82[53] | 0.45[54] | 1.29[55] |
9 | FGF7 | Fibroblast growth factor 7 | [56] | -9.86[57] | -6.39[58] | [59] | -6.48[60] | -2.44[61] | -3.03[62] |
10 | FGF5 | Fibroblast growth factor 5 | [63] | -1.56[64] | -0.46[65] | -0.80[66] | 0.37[67] | -0.17[68] | 1.55[69] |
11 | FGF1 | Fibroblast growth factor 1 | [70] | -3.33[71] | -2.77[72] | -7.49[73] | -0.52[74] | 0.83[75] | -1.54[76] |
12 | FGF8 | Fibroblast growth factor 8 | [77] | -3.90[78] | -3.78[79] | 0.46[80] | -3.03[81] | [82] | 1.11[83] |
13 | FGF18 | Fibroblast growth factor 18 | [84] | 1.21[85] | -3.13[86] | -1.22[87] | -0.49[88] | -0.13[89] | -1.00[90] |
14 | FGF9 | Fibroblast growth factor 9 | [91] | 1.69[92] | -2.19[93] | [94] | 1.67[95] | -3.67[96] | -1.48[97] |
15 | FGF6 | Fibroblast growth factor 6 | [98] | [99] | [100] | [101] | [102] | [103] | [104] |
16 | FGF4 | Fibroblast growth factor 4 | [105] | [106] | [107] | [108] | [109] | [110] | [111] |
17 | FGF16 | Fibroblast growth factor 16 | [112] | [113] | [114] | [115] | [116] | [117] | [118] |
18 | FGF23 | Fibroblast growth factor 23 | [119] | [120] | [121] | [122] | [123] | [124] | [125] |
19 | FGF20 | Fibroblast growth factor 20 | [126] | [127] | [128] | [129] | [130] | [131] | [132] |
20 | FGF3 | Fibroblast growth factor 3 | [133] | [134] | [135] | [136] | [137] | [138] | [139] |
21 | FGF17 | Fibroblast growth factor 17 | [140] | [141] | [142] | [143] | [144] | [145] | [146] |
22 | FGF10 | Fibroblast growth factor 10 | [147] | [148] | [149] | [150] | [151] | [152] | [153] |
23 | FGF22 | Fibroblast growth factor 22 | [154] | [155] | [156] | [157] | [158] | [159] | [160] |