REACTOME_PI5P_REGULATES_TP53_ACETYLATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [1] -2.07[2] -1.65[3] -1.86[4] -2.56[5] -1.14[6] -1.60[7]
2 TP53 Cellular tumor antigen p53 [8] 0.61[9] 0.53[10] 0.84[11] 0.39[12] 0.33[13] -0.28[14]
3 PIP4K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [15] 0.25[16] 0.55[17] -0.55[18] -0.34[19] -0.09[20] -0.29[21]
4 ING2 Inhibitor of growth protein 2 [22] -2.88[23] -2.31[24] -3.43[25] -2.76[26] -2.13[27] -2.56[28]
5 PIP4K2B Phosphatidylinositol 5-phosphate 4-kinase type-2 beta [29] 1.50[30] 1.44[31] 1.26[32] 1.54[33] 1.12[34] 0.92[35]
6 PIP4K2A Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [36] 0.61[37] 0.24[38] -0.15[39] 1.36[40] 0.59[41] 1.06[42]
7 EP300 Histone acetyltransferase p300 [43] 1.69[44] 1.65[45] 2.09[46] 1.67[47] 2.00[48] 2.51[49]
8 MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 [50] -0.74[51] -3.59[52] 0.81[53] 0.11[54] -3.65[55] -1.86[56]
9 PIP4P1 Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [57] [58] [59] [60] [61] [62] [63]
[1]
ref_hepatocyte PIN1
Mean 17.7
Standard deviation 5
Values 10 23 15 21 20
[2]
HepG2 PIN1
Mean 19
Standard deviation 0.013
Values 19 19
[3]
HepG2.C3A PIN1
Mean 17.6
Standard deviation 3.2
Values 15 20
[4]
HuH.7 PIN1
Mean 20
Standard deviation 7.8
Values 21 12 27
[5]
SNU475 PIN1
Mean 10.3
Standard deviation 1.6
Values 11 9.1
[6]
THLE PIN1
Mean 25.3
Standard deviation 2.3
Values 24 27
[7]
liver PIN1
Mean 9.77
Standard deviation 5.8
Values 15 4.4 15 5.2
[8]
ref_hepatocyte TP53
Mean 5.28
Standard deviation 0.94
Values 5.5 3.7 6.2 5.5 5.5
[9]
HepG2 TP53
Mean 36.3
Standard deviation 0.12
Values 36 36
[10]
HepG2.C3A TP53
Mean 23.9
Standard deviation 1.8
Values 23 25
[11]
HuH.7 TP53
Mean 38.7
Standard deviation 16
Values 50 20 46
[12]
SNU475 TP53
Mean 23.7
Standard deviation 6.7
Values 28 19
[13]
THLE TP53
Mean 21.1
Standard deviation 6.6
Values 16 26
[14]
liver TP53
Mean 7.29
Standard deviation 2.3
Values 9 5 9.5 5.6
[15]
ref_hepatocyte PIP4K2C
Mean 5.19
Standard deviation 1.5
Values 7.5 5 5.3 4.9 3.2
[16]
HepG2 PIP4K2C
Mean 27.9
Standard deviation 2.2
Values 26 29
[17]
HepG2.C3A PIP4K2C
Mean 23.8
Standard deviation 0.31
Values 24 24
[18]
HuH.7 PIP4K2C
Mean 14.6
Standard deviation 1.8
Values 15 13 16
[19]
SNU475 PIP4K2C
Mean 14.1
Standard deviation 1
Values 15 13
[20]
THLE PIP4K2C
Mean 15.4
Standard deviation 1.6
Values 14 17
[21]
liver PIP4K2C
Mean 7.13
Standard deviation 3.2
Values 9 4.8 11 4.1
[22]
ref_hepatocyte ING2
Mean 4.31
Standard deviation 0.71
Values 3.8 4.7 3.7 5.4 3.9
[23]
HepG2 ING2
Mean 2.64
Standard deviation 0.81
Values 2.1 3.2
[24]
HepG2.C3A ING2
Mean 2.72
Standard deviation 0.75
Values 2.2 3.2
[25]
HuH.7 ING2
Mean 1.64
Standard deviation 0.32
Values 1.4 1.5 2
[26]
SNU475 ING2
Mean 2.18
Standard deviation 0.61
Values 1.7 2.6
[27]
THLE ING2
Mean 3.12
Standard deviation 0.53
Values 3.5 2.8
[28]
liver ING2
Mean 1.23
Standard deviation 0.58
Values 1.8 0.91 1.7 0.57
[29]
ref_hepatocyte PIP4K2B
Mean 3.74
Standard deviation 2.2
Values 7.3 4.3 2 2.2 2.8
[30]
HepG2 PIP4K2B
Mean 47.8
Standard deviation 8.5
Values 42 54
[31]
HepG2.C3A PIP4K2B
Mean 31.7
Standard deviation 2.2
Values 30 33
[32]
HuH.7 PIP4K2B
Mean 36.8
Standard deviation 7.8
Values 44 28 38
[33]
SNU475 PIP4K2B
Mean 37.3
Standard deviation 4.5
Values 41 34
[34]
THLE PIP4K2B
Mean 25.8
Standard deviation 3.3
Values 23 28
[35]
liver PIP4K2B
Mean 11.9
Standard deviation 6.9
Values 6.9 17 5.1 19
[36]
ref_hepatocyte PIP4K2A
Mean 3.29
Standard deviation 2.4
Values 7.4 2.1 3.7 1.7 1.6
[37]
HepG2 PIP4K2A
Mean 22.6
Standard deviation 4.3
Values 20 26
[38]
HepG2.C3A PIP4K2A
Mean 12.2
Standard deviation 2.8
Values 10 14
[39]
HuH.7 PIP4K2A
Mean 12.2
Standard deviation 2
Values 14 13 9.9
[40]
SNU475 PIP4K2A
Mean 28.8
Standard deviation 4.6
Values 32 26
[41]
THLE PIP4K2A
Mean 15.7
Standard deviation 0.73
Values 15 16
[42]
liver PIP4K2A
Mean 11.5
Standard deviation 5.1
Values 14 7.7 18 6.9
[43]
ref_hepatocyte EP300
Mean 2.46
Standard deviation 1.2
Values 3 1.8 4.4 1.4 1.8
[44]
HepG2 EP300
Mean 35.9
Standard deviation 5.7
Values 32 40
[45]
HepG2.C3A EP300
Mean 24.1
Standard deviation 1.4
Values 23 25
[46]
HuH.7 EP300
Mean 43
Standard deviation 15
Values 55 48 26
[47]
SNU475 EP300
Mean 26.9
Standard deviation 1.3
Values 28 26
[48]
THLE EP300
Mean 31.2
Standard deviation 11
Values 23 39
[49]
liver EP300
Mean 23.6
Standard deviation 8
Values 20 27 15 33
[50]
ref_hepatocyte MAP2K6
Mean 1.65
Standard deviation 2.1
Values 5.3 0.69 0.17 0.98 1.1
[51]
HepG2 MAP2K6
Mean 4.46
Standard deviation 1.8
Values 3.2 5.7
[52]
HepG2.C3A MAP2K6
Mean 0.428
Standard deviation 0.00091
Values 0.43 0.43
[53]
HuH.7 MAP2K6
Mean 11.9
Standard deviation 2.1
Values 13 9.5 13
[54]
SNU475 MAP2K6
Mean 6.1
Standard deviation 1.1
Values 6.8 5.4
[55]
THLE MAP2K6
Mean 0.418
Standard deviation 0.064
Values 0.37 0.46
[56]
liver MAP2K6
Mean 0.764
Standard deviation 0.64
Values 1.6 0.61 0.051 0.79
[57]
ref_hepatocyte PIP4P1
Missing
[58]
HepG2 PIP4P1
Missing
[59]
HepG2.C3A PIP4P1
Missing
[60]
HuH.7 PIP4P1
Missing
[61]
SNU475 PIP4P1
Missing
[62]
THLE PIP4P1
Missing
[63]
liver PIP4P1
Missing