REACTOME_PI3K_AKT_SIGNALING_IN_CANCER Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RAC1 Ras-related C3 botulinum toxin substrate 1 [1] -1.13[2] -1.67[3] -1.01[4] -0.36[5] -0.66[6] -1.86[7]
2 CDKN1A Cyclin-dependent kinase inhibitor 1 [8] 0.10[9] -1.49[10] -4.24[11] -2.36[12] -0.09[13] -2.73[14]
3 AKT1 RAC-alpha serine/threonine-protein kinase [15] -0.65[16] -1.09[17] -2.23[18] -0.43[19] -0.69[20] -1.14[21]
4 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [22] -0.29[23] -0.07[24] -0.17[25] 0.51[26] 0.86[27] 0.36[28]
5 GRB2 Growth factor receptor-bound protein 2 [29] 0.46[30] 0.09[31] 0.16[32] 0.18[33] -0.19[34] -0.60[35]
6 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 [36] -0.75[37] -1.20[38] -1.04[39] -0.29[40] -0.39[41] -1.08[42]
7 RPS6KB2 Ribosomal protein S6 kinase beta-2 [43] [44] [45] [46] [47] [48] [49]
8 BAD Bcl2-associated agonist of cell death [50] -2.40[51] -2.48[52] -3.49[53] -1.44[54] -1.33[55] -2.32[56]
9 AKT1S1 Proline-rich AKT1 substrate 1 [57] -1.20[58] -1.56[59] -1.26[60] -1.13[61] -0.79[62] -2.09[63]
10 FGFR4 Fibroblast growth factor receptor 4 [64] 1.22[65] 1.35[66] 1.88[67] -4.61[68] -5.02[69] -0.40[70]
11 CDKN1B Cyclin-dependent kinase inhibitor 1B [71] -0.82[72] -0.59[73] -0.44[74] -1.48[75] -1.31[76] -1.80[77]
12 PIK3AP1 Phosphoinositide 3-kinase adapter protein 1 [78] -3.52[79] -1.36[80] -0.80[81] -3.31[82] -8.43[83] 1.60[84]
13 MET Hepatocyte growth factor receptor [85] -0.65[86] -0.83[87] -0.25[88] 1.16[89] -0.41[90] 0.07[91]
14 AKT2 RAC-beta serine/threonine-protein kinase [92] 0.22[93] 0.29[94] 0.37[95] 0.48[96] -0.01[97] 0.23[98]
15 MLST8 Target of rapamycin complex subunit LST8 [99] -0.91[100] -0.79[101] -0.47[102] -1.35[103] -1.29[104] -1.46[105]
16 KLB Beta-klotho [106] -0.14[107] -0.51[108] 0.88[109] -6.34[110] -7.27[111] 0.65[112]
17 GSK3A Glycogen synthase kinase-3 alpha [113] -0.11[114] -0.58[115] -0.54[116] -0.30[117] 0.18[118] -2.73[119]
18 ERBB3 Receptor tyrosine-protein kinase erbB-3 [120] 1.27[121] 2.44[122] 1.43[123] -6.25[124] -6.28[125] 1.41[126]
19 FGFR3 Fibroblast growth factor receptor 3 [127] 1.99[128] 1.70[129] 1.97[130] -3.67[131] -2.61[132] -0.45[133]
20 RHOG Rho-related GTP-binding protein RhoG [134] -0.47[135] -1.86[136] -1.97[137] -0.35[138] -1.07[139] -1.60[140]
21 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [141] -1.21[142] -1.30[143] -0.26[144] 1.69[145] 0.91[146] 2.10[147]
22 PRR5 Proline-rich protein 5 [148] -1.33[149] -1.48[150] -2.45[151] -2.66[152] -5.74[153] -1.68[154]
23 PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN -1.27[155] -0.09[156] 0.05[157] -0.94[158] 0.03[159] 1.58[160]
24 ERBB2 Receptor tyrosine-protein kinase erbB-2 [161] 1.64[162] 0.25[163] 1.36[164] 0.88[165] 0.20[166] -0.74[167]
25 MDM2 E3 ubiquitin-protein ligase Mdm2 [168] 1.37[169] 2.59[170] -0.23[171] 0.14[172] 0.72[173] 1.27[174]
26 EGFR Epidermal growth factor receptor [175] -1.43[176] -2.01[177] 0.81[178] 0.06[179] 0.39[180] 1.75[181]
27 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [182] 1.14[183] 1.15[184] 1.71[185] 0.33[186] 0.61[187] -1.19[188]
28 AREG Amphiregulin [189] -3.60[190] -7.05[191] -8.86[192] -10.07[193] -0.06[194] -11.21[195]
29 GSK3B Glycogen synthase kinase-3 beta [196] 0.53[197] -0.04[198] 0.48[199] 1.44[200] 0.98[201] 0.26[202]
30 FGF2 Fibroblast growth factor 2 [203] -7.42[204] -7.38[205] -3.28[206] 0.56[207] 1.85[208] -2.56[209]
31 CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha [210] 0.17[211] 1.18[212] 1.09[213] 0.28[214] 0.80[215] 0.62[216]
32 RAC2 Ras-related C3 botulinum toxin substrate 2 [217] -2.45[218] -8.65[219] -9.31[220] -1.77[221] 1.75[222] -2.13[223]
33 SRC Proto-oncogene tyrosine-protein kinase Src [224] 2.29[225] 2.07[226] 1.01[227] 2.02[228] 0.91[229] -1.75[230]
34 PDPK1 3-phosphoinositide-dependent protein kinase 1 [231] 1.60[232] 2.58[233] 1.23[234] 1.06[235] 1.17[236] 1.61[237]
35 MTOR Serine/threonine-protein kinase mTOR [238] 1.80[239] 2.60[240] 2.12[241] 2.31[242] 2.10[243] 2.55[244]
36 TSC2 Tuberin [245] 1.08[246] 0.40[247] 1.03[248] 0.83[249] 1.06[250] 1.18[251]
37 PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 0.48[252] 0.78[253] 0.88[254] 0.68[255] 0.55[256] 0.26[257]
38 IRS1 Insulin receptor substrate 1 [258] 1.36[259] 0.59[260] 1.96[261] 1.33[262] 0.63[263] 1.22[264]
39 FOXO3 Forkhead box protein O3 [265] -0.28[266] -0.40[267] 0.18[268] 0.03[269] 0.98[270] 1.43[271]
40 CASP9 Caspase-9 [272] -0.58[273] 0.17[274] -0.76[275] -0.13[276] -1.10[277] -1.43[278]
41 IRS2 Insulin receptor substrate 2 [279] -6.39[280] [281] -3.79[282] -1.04[283] 2.50[284] 1.49[285]
42 FYN Tyrosine-protein kinase Fyn [286] 0.21[287] -8.60[288] -0.09[289] 1.10[290] 2.34[291] 0.07[292]
43 TGFA Protransforming growth factor alpha [293] 1.06[294] 1.91[295] -9.19[296] -1.34[297] -2.85[298] -1.29[299]
44 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -1.11[300] 0.31[301] 0.45[302] 0.75[303] 0.67[304] 1.02[305]
45 PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1.15[306] 2.03[307] -1.84[308] -0.10[309] 0.38[310] -0.60[311]
46 HBEGF Proheparin-binding EGF-like growth factor [312] -1.72[313] -2.74[314] -3.87[315] -0.07[316] -0.67[317] -3.33[318]
47 CREB1 Cyclic AMP-responsive element-binding protein 1 [319] 0.99[320] 1.94[321] 2.37[322] 2.17[323] 1.82[324] 1.44[325]
48 FOXO1 Forkhead box protein O1 [326] 0.96[327] 0.42[328] 0.50[329] 0.80[330] 2.53[331] 2.19[332]
49 FLT3LG Fms-related tyrosine kinase 3 ligand [333] -2.99[334] -3.10[335] -2.70[336] -2.71[337] -1.91[338] -3.06[339]
50 PDGFA Platelet-derived growth factor subunit A [340] -1.74[341] -1.74[342] 0.29[343] -0.72[344] -1.91[345] -1.65[346]
51 RICTOR Rapamycin-insensitive companion of mTOR [347] -0.01[348] 1.86[349] 2.48[350] 1.98[351] 1.90[352] 2.62[353]
52 GAB2 GRB2-associated-binding protein 2 [354] 0.83[355] 0.41[356] 0.60[357] 0.55[358] 0.35[359] -0.35[360]
53 FOXO4 Forkhead box protein O4 [361] 0.00[362] 0.18[363] -0.04[364] -0.21[365] -0.28[366] -1.59[367]
54 ESR1 Estrogen receptor [368] -8.04[369] [370] -6.79[371] -4.54[372] -7.09[373] 1.50[374]
55 FGFR2 Fibroblast growth factor receptor 2 [375] -3.24[376] -2.25[377] 1.64[378] 1.08[379] -4.05[380] 2.53[381]
56 NRG1 Pro-neuregulin-1, membrane-bound isoform [382] -0.40[383] -6.75[384] -3.91[385] 1.68[386] -6.09[387] -0.13[388]
57 FRS2 Fibroblast growth factor receptor substrate 2 [389] 0.55[390] 1.44[391] 1.88[392] 2.53[393] 1.87[394] 2.44[395]
58 STRN Striatin [396] 1.23[397] 1.99[398] 1.55[399] 2.95[400] 2.56[401] 2.00[402]
59 NR4A1 Nuclear receptor subfamily 4 group A member 1 [403] 0.48[404] 0.82[405] 0.90[406] -0.23[407] 0.58[408] -0.37[409]
60 BTC Probetacellulin [410] -8.88[411] -9.48[412] -5.31[413] -3.25[414] -3.57[415] -3.81[416]
61 FGFR1 Fibroblast growth factor receptor 1 [417] 3.84[418] 1.95[419] 3.54[420] 4.68[421] 3.66[422] 0.76[423]
62 GAB1 GRB2-associated-binding protein 1 [424] 0.57[425] 1.45[426] 1.52[427] 1.56[428] 1.13[429] 1.98[430]
63 PDGFB Platelet-derived growth factor subunit B [431] 2.32[432] 1.98[433] -0.89[434] -0.31[435] -1.02[436] -0.53[437]
64 NRG4 Pro-neuregulin-4, membrane-bound isoform [438] -4.83[439] -2.16[440] -2.27[441] -0.09[442] -2.57[443] -1.83[444]
65 FGF7 Fibroblast growth factor 7 [445] -10.03[446] -6.54[447] [448] -5.75[449] -1.77[450] -2.35[451]
66 PDGFRA Platelet-derived growth factor receptor alpha [452] -4.35[453] -5.54[454] 2.04[455] 0.15[456] 4.54[457] 4.42[458]
67 PDGFRB Platelet-derived growth factor receptor beta [459] 0.56[460] 0.75[461] -1.76[462] 1.48[463] 1.75[464] 2.52[465]
68 VAV1 Proto-oncogene vav [466] -9.23[467] -4.61[468] -6.38[469] -6.46[470] -8.01[471] 0.28[472]
69 PIK3R3 Phosphatidylinositol 3-kinase regulatory subunit gamma [473] 0.99[474] 0.79[475] 1.58[476] 2.79[477] 1.53[478] 1.78[479]
70 CD86 T-lymphocyte activation antigen CD86 [480] [481] [482] -5.71[483] -4.47[484] -6.78[485] 0.45[486]
71 AKT3 RAC-gamma serine/threonine-protein kinase [487] -2.58[488] -5.34[489] -4.71[490] 5.47[491] 4.14[492] 2.71[493]
72 LCK Tyrosine-protein kinase Lck [494] 2.04[495] 1.91[496] -8.14[497] -5.46[498] -5.95[499] 0.34[500]
73 KL Klotho [501] -6.79[502] [503] [504] -1.77[505] -7.30[506] -0.65[507]
74 FGF5 Fibroblast growth factor 5 [508] -1.73[509] -0.61[510] -0.74[511] 1.11[512] 0.51[513] 2.24[514]
75 EREG Proepiregulin [515] 1.02[516] 0.74[517] -3.73[518] -1.94[519] 3.02[520] -2.37[521]
76 FGF1 Fibroblast growth factor 1 [522] -3.50[523] -2.92[524] -7.44[525] 0.21[526] 1.50[527] -0.86[528]
77 FGF19 Fibroblast growth factor 19 [529] -2.80[530] -1.85[531] 4.84[532] 0.45[533] -3.30[534] [535]
78 KITLG Kit ligand [536] 4.71[537] 0.72[538] 6.40[539] 6.36[540] 4.26[541] 2.14[542]
79 CD28 T-cell-specific surface glycoprotein CD28 [543] -4.74[544] -4.07[545] -4.10[546] -2.72[547] -3.06[548] 0.22[549]
80 KIT Mast/stem cell growth factor receptor Kit [550] -3.72[551] -5.82[552] [553] 2.13[554] -3.69[555] 2.74[556]
81 CD19 B-lymphocyte antigen CD19 [557] 1.37[558] 2.86[559] -2.03[560] -1.84[561] [562] 0.17[563]
82 CD80 T-lymphocyte activation antigen CD80 [564] [565] [566] -6.26[567] -1.53[568] -2.88[569] 1.73[570]
83 FLT3 Receptor-type tyrosine-protein kinase FLT3 [571] [572] [573] -4.50[574] -3.17[575] [576] 2.02[577]
84 ESR2 Estrogen receptor beta [578] -1.30[579] -1.14[580] -1.17[581] 0.26[582] 0.07[583] 1.63[584]
85 TRAT1 T-cell receptor-associated transmembrane adapter 1 [585] [586] [587] [588] [589] [590] 1.89[591]
86 ICOS Inducible T-cell costimulator [592] [593] -4.32[594] [595] [596] [597] -1.46[598]
87 HGF Hepatocyte growth factor [599] [600] [601] -2.65[602] 4.22[603] 0.96[604] 8.00[605]
88 FGF8 Fibroblast growth factor 8 [606] -4.06[607] -3.92[608] 0.51[609] -2.29[610] [611] 1.80[612]
89 FGF18 Fibroblast growth factor 18 [613] 1.04[614] -3.28[615] -1.16[616] 0.24[617] 0.55[618] -0.31[619]
90 FGF9 Fibroblast growth factor 9 [620] 1.52[621] -2.34[622] [623] 2.41[624] -2.99[625] -0.79[626]
91 EGF Pro-epidermal growth factor [627] 1.23[628] 2.81[629] 6.37[630] 8.65[631] 5.78[632] 0.68[633]
92 FGF3 Fibroblast growth factor 3 [634] [635] [636] [637] [638] [639] [640]
93 FGF20 Fibroblast growth factor 20 [641] [642] [643] [644] [645] [646] [647]
94 FGF23 Fibroblast growth factor 23 [648] [649] [650] [651] [652] [653] [654]
95 FGF22 Fibroblast growth factor 22 [655] [656] [657] [658] [659] [660] [661]
96 FGF10 Fibroblast growth factor 10 [662] [663] [664] [665] [666] [667] [668]
97 FGF17 Fibroblast growth factor 17 [669] [670] [671] [672] [673] [674] [675]
98 NRG3 Pro-neuregulin-3, membrane-bound isoform [676] [677] [678] [679] [680] [681] [682]
99 FGF4 Fibroblast growth factor 4 [683] [684] [685] [686] [687] [688] [689]
100 FGF16 Fibroblast growth factor 16 [690] [691] [692] [693] [694] [695] [696]
101 ERBB4 Receptor tyrosine-protein kinase erbB-4 [697] [698] [699] [700] [701] [702] [703]
102 EPGN Epigen [704] [705] [706] [707] [708] [709] [710]
103 FGF6 Fibroblast growth factor 6 [711] [712] [713] [714] [715] [716] [717]
104 NRG2 Pro-neuregulin-2, membrane-bound isoform [718] [719] [720] [721] [722] [723] [724]
105 FOXO6 Forkhead box protein O6 [725] [726] [727] [728] [729] [730] [731]
[1]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[2]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[3]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[4]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[5]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[6]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[7]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[8]
ref_hepatocyte CDKN1A
Mean 40.1
Standard deviation 28
Values 19 48 76 52 5.7
[9]
HepG2 CDKN1A
Mean 158
Standard deviation 49
Values 1.9e+02 1.2e+02
[10]
HepG2.C3A CDKN1A
Mean 53.9
Standard deviation 3.9
Values 51 57
[11]
HuH.7 CDKN1A
Mean 8
Standard deviation 1.9
Values 6.5 10 7.3
[12]
SNU475 CDKN1A
Mean 18.6
Standard deviation 7.8
Values 13 24
[13]
THLE CDKN1A
Mean 122
Standard deviation 11
Values 1.3e+02 1.1e+02
[14]
liver CDKN1A
Mean 16
Standard deviation 8.1
Values 16 6.2 26 16
[15]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[16]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[17]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[18]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[19]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[20]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[21]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[22]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[23]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[24]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[25]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[26]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[27]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[28]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[29]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[30]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[31]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[32]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[33]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[34]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[35]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[36]
ref_hepatocyte MAPKAP1
Mean 18.9
Standard deviation 8.4
Values 14 33 18 16 13
[37]
HepG2 MAPKAP1
Mean 41.3
Standard deviation 6.5
Values 37 46
[38]
HepG2.C3A MAPKAP1
Mean 31
Standard deviation 5.4
Values 27 35
[39]
HuH.7 MAPKAP1
Mean 34.6
Standard deviation 7.1
Values 38 26 40
[40]
SNU475 MAPKAP1
Mean 36.6
Standard deviation 8.3
Values 43 31
[41]
THLE MAPKAP1
Mean 46.7
Standard deviation 15
Values 36 57
[42]
liver MAPKAP1
Mean 23.6
Standard deviation 2.7
Values 23 26 20 25
[43]
ref_hepatocyte RPS6KB2
Mean 17
Standard deviation 4.8
Values 17 25 15 15 13
[44]
HepG2 RPS6KB2
Missing
[45]
HepG2.C3A RPS6KB2
Missing
[46]
HuH.7 RPS6KB2
Missing
[47]
SNU475 RPS6KB2
Missing
[48]
THLE RPS6KB2
Missing
[49]
liver RPS6KB2
Missing
[50]
ref_hepatocyte BAD
Mean 16.7
Standard deviation 11
Values 5.4 16 6.7 28 27
[51]
HepG2 BAD
Mean 11.6
Standard deviation 0.78
Values 11 12
[52]
HepG2.C3A BAD
Mean 11.3
Standard deviation 1.1
Values 10 12
[53]
HuH.7 BAD
Mean 5.61
Standard deviation 0.7
Values 5 6.4 5.5
[54]
SNU475 BAD
Mean 14.6
Standard deviation 2.5
Values 16 13
[55]
THLE BAD
Mean 21.6
Standard deviation 1.3
Values 21 23
[56]
liver BAD
Mean 8.85
Standard deviation 6.2
Values 16 3.7 12 3.7
[57]
ref_hepatocyte AKT1S1
Mean 16.3
Standard deviation 7.1
Values 9.3 9.6 22 25 16
[58]
HepG2 AKT1S1
Mean 26.1
Standard deviation 2.4
Values 24 28
[59]
HepG2.C3A AKT1S1
Mean 20.9
Standard deviation 0.11
Values 21 21
[60]
HuH.7 AKT1S1
Mean 25.6
Standard deviation 5
Values 30 20 27
[61]
SNU475 AKT1S1
Mean 17.8
Standard deviation 0.54
Values 18 17
[62]
THLE AKT1S1
Mean 30.7
Standard deviation 8
Values 25 36
[63]
liver AKT1S1
Mean 10.2
Standard deviation 7
Values 14 4.3 18 4.2
[64]
ref_hepatocyte FGFR4
Mean 15.1
Standard deviation 12
Values 30 2.5 2.2 18 23
[65]
HepG2 FGFR4
Mean 129
Standard deviation 13
Values 1.2e+02 1.4e+02
[66]
HepG2.C3A FGFR4
Mean 146
Standard deviation 22
Values 1.6e+02 1.3e+02
[67]
HuH.7 FGFR4
Mean 209
Standard deviation 68
Values 2.4e+02 1.3e+02 2.5e+02
[68]
SNU475 FGFR4
Mean 1.47
Standard deviation 0.43
Values 1.2 1.8
[69]
THLE FGFR4
Mean 1.51
Standard deviation 0.45
Values 1.8 1.2
[70]
liver FGFR4
Mean 30.3
Standard deviation 10
Values 43 18 31 29
[71]
ref_hepatocyte CDKN1B
Mean 13.8
Standard deviation 6
Values 23 13 7.5 10 15
[72]
HepG2 CDKN1B
Mean 28.7
Standard deviation 3.4
Values 31 26
[73]
HepG2.C3A CDKN1B
Mean 34.7
Standard deviation 1.4
Values 34 36
[74]
HuH.7 CDKN1B
Mean 38.2
Standard deviation 3.7
Values 35 42 37
[75]
SNU475 CDKN1B
Mean 11.8
Standard deviation 2.9
Values 14 9.7
[76]
THLE CDKN1B
Mean 18.2
Standard deviation 3.4
Values 16 21
[77]
liver CDKN1B
Mean 10.5
Standard deviation 3.5
Values 9.9 14 5.8 12
[78]
ref_hepatocyte PIK3AP1
Mean 13.4
Standard deviation 11
Values 1.4 7.1 11 20 28
[79]
HepG2 PIK3AP1
Mean 4.31
Standard deviation 2.2
Values 2.7 5.9
[80]
HepG2.C3A PIK3AP1
Mean 19.8
Standard deviation 2.9
Values 18 22
[81]
HuH.7 PIK3AP1
Mean 29.2
Standard deviation 4.3
Values 34 26 27
[82]
SNU475 PIK3AP1
Mean 3.24
Standard deviation 0.93
Values 3.9 2.6
[83]
THLE PIK3AP1
Mean 0.127
Standard deviation 0.046
Values 0.095 0.16
[84]
liver PIK3AP1
Mean 108
Standard deviation 35
Values 61 1.4e+02 1.1e+02 1.2e+02
[85]
ref_hepatocyte MET
Mean 12.9
Standard deviation 12
Values 6.9 32 16 3.7 5.7
[86]
HepG2 MET
Mean 30.2
Standard deviation 2.7
Values 32 28
[87]
HepG2.C3A MET
Mean 27.5
Standard deviation 6.5
Values 23 32
[88]
HuH.7 MET
Mean 40.8
Standard deviation 7.3
Values 43 47 33
[89]
SNU475 MET
Mean 68.7
Standard deviation 7.1
Values 64 74
[90]
THLE MET
Mean 31.7
Standard deviation 2
Values 33 30
[91]
liver MET
Mean 35.9
Standard deviation 13
Values 27 46 22 48
[92]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 7.2 8.4 11 13 14
[93]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 48 43
[94]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 55 43
[95]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 59 41 55
[96]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 39 31
[97]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[98]
liver AKT2
Mean 33
Standard deviation 9.4
Values 24 36 27 45
[99]
ref_hepatocyte MLST8
Mean 10
Standard deviation 3.8
Values 7 5.5 14 14 10
[100]
HepG2 MLST8
Mean 19.6
Standard deviation 1.4
Values 21 19
[101]
HepG2.C3A MLST8
Mean 22
Standard deviation 3.6
Values 24 19
[102]
HuH.7 MLST8
Mean 27.2
Standard deviation 3.6
Values 28 23 30
[103]
SNU475 MLST8
Mean 9.36
Standard deviation 0.84
Values 9.9 8.8
[104]
THLE MLST8
Mean 13.3
Standard deviation 1.9
Values 12 15
[105]
liver MLST8
Mean 9.64
Standard deviation 7.6
Values 17 2.5 15 3.8
[106]
ref_hepatocyte KLB
Mean 9.92
Standard deviation 12
Values 30 1.9 0.71 6.7 9.9
[107]
HepG2 KLB
Mean 33.1
Standard deviation 23
Values 17 49
[108]
HepG2.C3A KLB
Mean 26.3
Standard deviation 0.12
Values 26 26
[109]
HuH.7 KLB
Mean 68.9
Standard deviation 30
Values 57 1e+02 46
[110]
SNU475 KLB
Mean 0.292
Standard deviation 0.04
Values 0.32 0.26
[111]
THLE KLB
Mean 0.21
Standard deviation 0.004
Values 0.21 0.21
[112]
liver KLB
Mean 41.2
Standard deviation 7.6
Values 52 37 40 36
[113]
ref_hepatocyte GSK3A
Mean 9.38
Standard deviation 5.1
Values 7.5 3.9 17 12 6.4
[114]
HepG2 GSK3A
Mean 31.9
Standard deviation 3.3
Values 34 30
[115]
HepG2.C3A GSK3A
Mean 23.7
Standard deviation 0.26
Values 24 24
[116]
HuH.7 GSK3A
Mean 24.3
Standard deviation 3.3
Values 26 21 26
[117]
SNU475 GSK3A
Mean 18.2
Standard deviation 1.9
Values 17 20
[118]
THLE GSK3A
Mean 34.6
Standard deviation 4.3
Values 32 38
[119]
liver GSK3A
Mean 3.74
Standard deviation 0.84
Values 4.7 3.1 3 4.2
[120]
ref_hepatocyte ERBB3
Mean 8.22
Standard deviation 4
Values 12 3.8 4.1 11 10
[121]
HepG2 ERBB3
Mean 72.9
Standard deviation 2.6
Values 75 71
[122]
HepG2.C3A ERBB3
Mean 169
Standard deviation 42
Values 2e+02 1.4e+02
[123]
HuH.7 ERBB3
Mean 83.4
Standard deviation 7.8
Values 92 80 78
[124]
SNU475 ERBB3
Mean 0.258
Standard deviation 0.12
Values 0.18 0.34
[125]
THLE ERBB3
Mean 0.344
Standard deviation 0.05
Values 0.38 0.31
[126]
liver ERBB3
Mean 57.8
Standard deviation 20
Values 44 71 39 79
[127]
ref_hepatocyte FGFR3
Mean 7.46
Standard deviation 9.2
Values 23 2.7 0.18 4.6 6.4
[128]
HepG2 FGFR3
Mean 109
Standard deviation 1.1
Values 1.1e+02 1.1e+02
[129]
HepG2.C3A FGFR3
Mean 91.5
Standard deviation 12
Values 1e+02 83
[130]
HuH.7 FGFR3
Mean 110
Standard deviation 12
Values 1.2e+02 97 1.2e+02
[131]
SNU475 FGFR3
Mean 1.4
Standard deviation 0.25
Values 1.6 1.2
[132]
THLE FGFR3
Mean 3.99
Standard deviation 0.31
Values 3.8 4.2
[133]
liver FGFR3
Mean 14.5
Standard deviation 8.7
Values 9.3 18 5.8 25
[134]
ref_hepatocyte RHOG
Mean 7.46
Standard deviation 3.9
Values 2.6 4.7 11 11 7.4
[135]
HepG2 RHOG
Mean 19.8
Standard deviation 1.5
Values 21 19
[136]
HepG2.C3A RHOG
Mean 7.77
Standard deviation 0.56
Values 8.2 7.4
[137]
HuH.7 RHOG
Mean 7.15
Standard deviation 1.1
Values 8.1 5.9 7.5
[138]
SNU475 RHOG
Mean 14
Standard deviation 0.77
Values 13 14
[139]
THLE RHOG
Mean 11.6
Standard deviation 2.4
Values 9.9 13
[140]
liver RHOG
Mean 6.51
Standard deviation 5.8
Values 13 1.6 10 1.6
[141]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[142]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[143]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[144]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[145]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[146]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[147]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[148]
ref_hepatocyte PRR5
Mean 7.43
Standard deviation 4.5
Values 11 2 3.1 10 11
[149]
HepG2 PRR5
Mean 10.9
Standard deviation 2.6
Values 13 9.1
[150]
HepG2.C3A PRR5
Mean 10.1
Standard deviation 0.29
Values 10 9.9
[151]
HuH.7 PRR5
Mean 5.13
Standard deviation 0.59
Values 4.7 4.9 5.8
[152]
SNU475 PRR5
Mean 2.8
Standard deviation 0.093
Values 2.7 2.9
[153]
THLE PRR5
Mean 0.452
Standard deviation 0.2
Values 0.31 0.59
[154]
liver PRR5
Mean 6.15
Standard deviation 3.4
Values 7.7 2.9 10 3.9
[155]
ref_hepatocyte PTEN
Mean 6.57
Standard deviation 2.4
Values 4.2 5.9 5.2 7 11
[156]
HepG2 PTEN
Mean 9.98
Standard deviation 2.3
Values 8.4 12
[157]
HepG2.C3A PTEN
Mean 23.3
Standard deviation 3.3
Values 26 21
[158]
HuH.7 PTEN
Mean 25.7
Standard deviation 12
Values 19 39 19
[159]
SNU475 PTEN
Mean 8.16
Standard deviation 1.8
Values 9.4 6.9
[160]
THLE PTEN
Mean 21.8
Standard deviation 0.98
Values 22 21
[161]
liver PTEN
Mean 52
Standard deviation 9.3
Values 61 55 39 53
[162]
ref_hepatocyte ERBB2
Mean 6.44
Standard deviation 3.8
Values 13 3.9 4.7 3.7 7.1
[163]
HepG2 ERBB2
Mean 73.6
Standard deviation 10
Values 66 81
[164]
HepG2.C3A ERBB2
Mean 29
Standard deviation 6.9
Values 34 24
[165]
HuH.7 ERBB2
Mean 62.5
Standard deviation 7.1
Values 69 55 63
[166]
SNU475 ERBB2
Mean 28.2
Standard deviation 8.4
Values 34 22
[167]
THLE ERBB2
Mean 24.1
Standard deviation 2.7
Values 22 26
[168]
liver ERBB2
Mean 10.2
Standard deviation 3.4
Values 7.9 8.1 9.6 15
[169]
ref_hepatocyte MDM2
Mean 6.36
Standard deviation 2.9
Values 11 7.6 5 3.6 4.8
[170]
HepG2 MDM2
Mean 60.6
Standard deviation 13
Values 51 70
[171]
HepG2.C3A MDM2
Mean 145
Standard deviation 52
Values 1.1e+02 1.8e+02
[172]
HuH.7 MDM2
Mean 20.4
Standard deviation 0.31
Values 21 20 20
[173]
SNU475 MDM2
Mean 16.7
Standard deviation 1.8
Values 18 15
[174]
THLE MDM2
Mean 34.2
Standard deviation 0.86
Values 35 34
[175]
liver MDM2
Mean 40.5
Standard deviation 11
Values 29 54 35 45
[176]
ref_hepatocyte EGFR
Mean 5.53
Standard deviation 4.2
Values 0.94 8.5 11 3.5 3.5
[177]
HepG2 EGFR
Mean 7.53
Standard deviation 0.89
Values 6.9 8.2
[178]
HepG2.C3A EGFR
Mean 5.18
Standard deviation 0.67
Values 5.7 4.7
[179]
HuH.7 EGFR
Mean 36.6
Standard deviation 25
Values 32 63 15
[180]
SNU475 EGFR
Mean 13.7
Standard deviation 0.74
Values 13 14
[181]
THLE EGFR
Mean 23.6
Standard deviation 4.4
Values 20 27
[182]
liver EGFR
Mean 49.4
Standard deviation 14
Values 39 69 47 42
[183]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 11 3.2 3.1 4.9 3.8
[184]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 44 41
[185]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 53 35
[186]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 75 55 64
[187]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 18 13
[188]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[189]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 7.6 6 3.8 6.9
[190]
ref_hepatocyte AREG
Mean 5.24
Standard deviation 9.3
Values 1.7 22 1.7 0.57 0.4
[191]
HepG2 AREG
Mean 1.59
Standard deviation 1.3
Values 2.5 0.67
[192]
HepG2.C3A AREG
Mean 0.15
Standard deviation 0.061
Values 0.11 0.19
[193]
HuH.7 AREG
Mean 0.0425
Standard deviation 0.021
Values 0.057 0.051 0.019
[194]
SNU475 AREG
Mean 0.0116
Standard deviation 0.016
Values 0.023 0
[195]
THLE AREG
Mean 16.4
Standard deviation 1.7
Values 15 18
[196]
liver AREG
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[197]
ref_hepatocyte GSK3B
Mean 4.16
Standard deviation 1.7
Values 5.2 5.9 4.9 2.7 2.1
[198]
HepG2 GSK3B
Mean 22.1
Standard deviation 6
Values 18 26
[199]
HepG2.C3A GSK3B
Mean 15.3
Standard deviation 2.3
Values 14 17
[200]
HuH.7 GSK3B
Mean 21.8
Standard deviation 5.6
Values 24 26 15
[201]
SNU475 GSK3B
Mean 26.9
Standard deviation 2.6
Values 29 25
[202]
THLE GSK3B
Mean 26.7
Standard deviation 2.9
Values 25 29
[203]
liver GSK3B
Mean 13.2
Standard deviation 3.2
Values 14 15 8.6 16
[204]
ref_hepatocyte FGF2
Mean 4.04
Standard deviation 6.5
Values 0.052 15 3.7 0.37 0.73
[205]
HepG2 FGF2
Mean 0.0866
Standard deviation 0.08
Values 0.14 0.03
[206]
HepG2.C3A FGF2
Mean 0.092
Standard deviation 0.0064
Values 0.087 0.097
[207]
HuH.7 FGF2
Mean 1.57
Standard deviation 0.89
Values 0.98 2.6 1.1
[208]
SNU475 FGF2
Mean 14.2
Standard deviation 1.3
Values 13 15
[209]
THLE FGF2
Mean 47.5
Standard deviation 0.66
Values 48 47
[210]
liver FGF2
Mean 1.81
Standard deviation 0.66
Values 1.9 2.5 0.9 2
[211]
ref_hepatocyte CHUK
Mean 3.93
Standard deviation 1.2
Values 4.2 5.7 2.3 3.4 4.1
[212]
HepG2 CHUK
Mean 16.2
Standard deviation 6.4
Values 12 21
[213]
HepG2.C3A CHUK
Mean 33.6
Standard deviation 13
Values 25 43
[214]
HuH.7 CHUK
Mean 31.4
Standard deviation 3.3
Values 34 28 32
[215]
SNU475 CHUK
Mean 11.3
Standard deviation 1.1
Values 11 12
[216]
THLE CHUK
Mean 22.3
Standard deviation 0.15
Values 22 22
[217]
liver CHUK
Mean 16
Standard deviation 3.3
Values 13 21 15 15
[218]
ref_hepatocyte RAC2
Mean 3.71
Standard deviation 4.6
Values 0 0.72 11 1.6 5.1
[219]
HepG2 RAC2
Mean 2.5
Standard deviation 2.1
Values 4 1
[220]
HepG2.C3A RAC2
Mean 0.035
Standard deviation 0.019
Values 0.049 0.021
[221]
HuH.7 RAC2
Mean 0.0221
Standard deviation 0.018
Values 0.041 0.0064 0.019
[222]
SNU475 RAC2
Mean 2.6
Standard deviation 0.081
Values 2.5 2.7
[223]
THLE RAC2
Mean 40.7
Standard deviation 12
Values 32 49
[224]
liver RAC2
Mean 2.24
Standard deviation 1.8
Values 3.9 0.44 3.7 0.86
[225]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[226]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[227]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[228]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[229]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[230]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[231]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[232]
ref_hepatocyte PDPK1
Mean 3.54
Standard deviation 2
Values 6.9 3.4 3.6 1.8 2
[233]
HepG2 PDPK1
Mean 39.4
Standard deviation 5.6
Values 35 43
[234]
HepG2.C3A PDPK1
Mean 80.1
Standard deviation 13
Values 89 71
[235]
HuH.7 PDPK1
Mean 31.4
Standard deviation 4.5
Values 35 33 26
[236]
SNU475 PDPK1
Mean 17.6
Standard deviation 0.21
Values 17 18
[237]
THLE PDPK1
Mean 25.9
Standard deviation 4.6
Values 23 29
[238]
liver PDPK1
Mean 28.5
Standard deviation 5.1
Values 34 27 22 31
[239]
ref_hepatocyte MTOR
Mean 3.34
Standard deviation 0.62
Values 2.6 3.1 4.3 3.5 3.2
[240]
HepG2 MTOR
Mean 42.7
Standard deviation 6.3
Values 38 47
[241]
HepG2.C3A MTOR
Mean 76.8
Standard deviation 17
Values 89 65
[242]
HuH.7 MTOR
Mean 54.5
Standard deviation 17
Values 73 50 41
[243]
SNU475 MTOR
Mean 39.4
Standard deviation 0.66
Values 39 40
[244]
THLE MTOR
Mean 46.6
Standard deviation 4.9
Values 43 50
[245]
liver MTOR
Mean 51.8
Standard deviation 18
Values 34 72 39 62
[246]
ref_hepatocyte TSC2
Mean 3.2
Standard deviation 0.13
Values 3.1 3.1 3.2 3.2 3.4
[247]
HepG2 TSC2
Mean 24.9
Standard deviation 3.4
Values 27 22
[248]
HepG2.C3A TSC2
Mean 16
Standard deviation 4.7
Values 19 13
[249]
HuH.7 TSC2
Mean 24.6
Standard deviation 4
Values 29 24 21
[250]
SNU475 TSC2
Mean 13.5
Standard deviation 5
Values 17 10
[251]
THLE TSC2
Mean 21.8
Standard deviation 1.7
Values 21 23
[252]
liver TSC2
Mean 19.2
Standard deviation 2.2
Values 17 19 18 22
[253]
ref_hepatocyte PIK3CB
Mean 3.18
Standard deviation 1.5
Values 5.2 4.2 2.6 1.8 2.1
[254]
HepG2 PIK3CB
Mean 16.3
Standard deviation 2.1
Values 15 18
[255]
HepG2.C3A PIK3CB
Mean 20.6
Standard deviation 2.7
Values 23 19
[256]
HuH.7 PIK3CB
Mean 22.1
Standard deviation 2.1
Values 24 23 20
[257]
SNU475 PIK3CB
Mean 12.1
Standard deviation 2.7
Values 14 10
[258]
THLE PIK3CB
Mean 15.1
Standard deviation 0.94
Values 14 16
[259]
liver PIK3CB
Mean 10.1
Standard deviation 3.7
Values 6.4 15 7.9 11
[260]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 4.3 1.5 2.7 2.1 4.7
[261]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 35 23
[262]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 22 13
[263]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 49 48 37
[264]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 15 22
[265]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[266]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 23 18 12 22
[267]
ref_hepatocyte FOXO3
Mean 2.79
Standard deviation 0.38
Values 3.3 2.7 2.3 2.8 2.9
[268]
HepG2 FOXO3
Mean 8.44
Standard deviation 1
Values 7.7 9.2
[269]
HepG2.C3A FOXO3
Mean 8
Standard deviation 2.4
Values 9.7 6.3
[270]
HuH.7 FOXO3
Mean 11.9
Standard deviation 3.6
Values 13 15 7.9
[271]
SNU475 FOXO3
Mean 6.76
Standard deviation 0.76
Values 7.3 6.2
[272]
THLE FOXO3
Mean 17.9
Standard deviation 3.1
Values 16 20
[273]
liver FOXO3
Mean 20
Standard deviation 5.5
Values 24 21 12 23
[274]
ref_hepatocyte CASP9
Mean 2.59
Standard deviation 1
Values 1.9 1.9 2 2.7 4.4
[275]
HepG2 CASP9
Mean 6.38
Standard deviation 0.81
Values 5.8 7
[276]
HepG2.C3A CASP9
Mean 11.1
Standard deviation 0.21
Values 11 11
[277]
HuH.7 CASP9
Mean 5.76
Standard deviation 1.5
Values 6.7 4.1 6.6
[278]
SNU475 CASP9
Mean 5.65
Standard deviation 0.92
Values 6.3 5
[279]
THLE CASP9
Mean 3.94
Standard deviation 0.43
Values 3.6 4.2
[280]
liver CASP9
Mean 2.54
Standard deviation 1.2
Values 2.4 1.9 4.2 1.6
[281]
ref_hepatocyte IRS2
Mean 2.12
Standard deviation 2.3
Values 0.019 0.61 1.4 5.7 2.9
[282]
HepG2 IRS2
Mean 0.0931
Standard deviation 0.071
Values 0.14 0.043
[283]
HepG2.C3A IRS2
Mean 0
Standard deviation 0
Values 0 0
[284]
HuH.7 IRS2
Mean 0.575
Standard deviation 0.68
Values 0.2 1.4 0.17
[285]
SNU475 IRS2
Mean 2.45
Standard deviation 0.45
Values 2.1 2.8
[286]
THLE IRS2
Mean 39
Standard deviation 5.9
Values 35 43
[287]
liver IRS2
Mean 15.7
Standard deviation 9.9
Values 29 11 6.3 17
[288]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 2.2 0.039 0.23 2.6 5.5
[289]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 9.4 8.4
[290]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[291]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.9 4.8 8.5
[292]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 12 8.9
[293]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[294]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 8.9 4.4 5.1 5
[295]
ref_hepatocyte TGFA
Mean 2
Standard deviation 1.3
Values 3.8 2.7 2.1 0.72 0.76
[296]
HepG2 TGFA
Mean 15.3
Standard deviation 2.1
Values 17 14
[297]
HepG2.C3A TGFA
Mean 28.4
Standard deviation 4.2
Values 25 31
[298]
HuH.7 TGFA
Mean 0.0129
Standard deviation 0.0035
Values 0.016 0.013 0.0094
[299]
SNU475 TGFA
Mean 1.88
Standard deviation 0.53
Values 1.5 2.3
[300]
THLE TGFA
Mean 0.903
Standard deviation 0.47
Values 1.2 0.57
[301]
liver TGFA
Mean 2.16
Standard deviation 0.15
Values 2.1 2.3 2.2 2
[302]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[303]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[304]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[305]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[306]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[307]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[308]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[309]
ref_hepatocyte PIK3CD
Mean 1.86
Standard deviation 1.7
Values 4.1 0.94 3.3 0.38 0.66
[310]
HepG2 PIK3CD
Mean 15.2
Standard deviation 3.8
Values 18 13
[311]
HepG2.C3A PIK3CD
Mean 28.8
Standard deviation 2.6
Values 31 27
[312]
HuH.7 PIK3CD
Mean 1.97
Standard deviation 0.32
Values 2 2.3 1.6
[313]
SNU475 PIK3CD
Mean 4.15
Standard deviation 0.57
Values 4.6 3.7
[314]
THLE PIK3CD
Mean 7.91
Standard deviation 1.1
Values 7.1 8.7
[315]
liver PIK3CD
Mean 3.25
Standard deviation 1.3
Values 2.4 3 2.6 5.1
[316]
ref_hepatocyte HBEGF
Mean 1.81
Standard deviation 1.5
Values 1 3.1 3.8 0.78 0.34
[317]
HepG2 HBEGF
Mean 2.02
Standard deviation 0.16
Values 2.1 1.9
[318]
HepG2.C3A HBEGF
Mean 1.02
Standard deviation 0.3
Values 1.2 0.82
[319]
HuH.7 HBEGF
Mean 0.469
Standard deviation 0.044
Values 0.52 0.43 0.46
[320]
SNU475 HBEGF
Mean 4.11
Standard deviation 0.34
Values 3.9 4.4
[321]
THLE HBEGF
Mean 3.71
Standard deviation 0.17
Values 3.8 3.6
[322]
liver HBEGF
Mean 0.478
Standard deviation 0.29
Values 0.89 0.27 0.28 0.46
[323]
ref_hepatocyte CREB1
Mean 1.8
Standard deviation 1.2
Values 3.7 2.1 1.5 0.96 0.81
[324]
HepG2 CREB1
Mean 13.1
Standard deviation 2.8
Values 11 15
[325]
HepG2.C3A CREB1
Mean 26.1
Standard deviation 3.2
Values 24 28
[326]
HuH.7 CREB1
Mean 35.1
Standard deviation 4
Values 38 36 31
[327]
SNU475 CREB1
Mean 19.3
Standard deviation 0.081
Values 19 19
[328]
THLE CREB1
Mean 20.8
Standard deviation 2.1
Values 22 19
[329]
liver CREB1
Mean 13
Standard deviation 3.1
Values 12 16 9.3 15
[330]
ref_hepatocyte FOXO1
Mean 1.77
Standard deviation 0.68
Values 0.71 1.7 2 1.9 2.6
[331]
HepG2 FOXO1
Mean 12.6
Standard deviation 1.8
Values 11 14
[332]
HepG2.C3A FOXO1
Mean 8.92
Standard deviation 1.5
Values 10 7.9
[333]
HuH.7 FOXO1
Mean 9.41
Standard deviation 1.6
Values 10 10 7.6
[334]
SNU475 FOXO1
Mean 7.33
Standard deviation 1.8
Values 8.6 6
[335]
THLE FOXO1
Mean 33.2
Standard deviation 1.9
Values 32 35
[336]
liver FOXO1
Mean 21.4
Standard deviation 7
Values 25 19 13 29
[337]
ref_hepatocyte FLT3LG
Mean 1.73
Standard deviation 1.8
Values 0 0 4.1 1.9 2.7
[338]
HepG2 FLT3LG
Mean 0.799
Standard deviation 0.045
Values 0.83 0.77
[339]
HepG2.C3A FLT3LG
Mean 0.761
Standard deviation 0.27
Values 0.95 0.57
[340]
HuH.7 FLT3LG
Mean 1.01
Standard deviation 0.09
Values 1 1.1 0.92
[341]
SNU475 FLT3LG
Mean 0.629
Standard deviation 0.022
Values 0.64 0.61
[342]
THLE FLT3LG
Mean 1.5
Standard deviation 0.22
Values 1.7 1.3
[343]
liver FLT3LG
Mean 0.55
Standard deviation 0.58
Values 1.3 0.1 0.62 0.15
[344]
ref_hepatocyte PDGFA
Mean 1.67
Standard deviation 1.7
Values 0.21 1.9 4.5 1.6 0.2
[345]
HepG2 PDGFA
Mean 1.84
Standard deviation 0.32
Values 2.1 1.6
[346]
HepG2.C3A PDGFA
Mean 1.9
Standard deviation 0.64
Values 2.4 1.4
[347]
HuH.7 PDGFA
Mean 7.72
Standard deviation 1.4
Values 7.9 9 6.2
[348]
SNU475 PDGFA
Mean 2.43
Standard deviation 0.11
Values 2.5 2.3
[349]
THLE PDGFA
Mean 1.44
Standard deviation 0.18
Values 1.3 1.6
[350]
liver PDGFA
Mean 1.41
Standard deviation 0.21
Values 1.3 1.4 1.7 1.2
[351]
ref_hepatocyte RICTOR
Mean 1.67
Standard deviation 0.88
Values 2.2 2.1 2.6 0.49 1
[352]
HepG2 RICTOR
Mean 6.11
Standard deviation 1
Values 5.4 6.8
[353]
HepG2.C3A RICTOR
Mean 23
Standard deviation 1
Values 22 24
[354]
HuH.7 RICTOR
Mean 35.2
Standard deviation 17
Values 31 54 21
[355]
SNU475 RICTOR
Mean 15.7
Standard deviation 0.97
Values 16 15
[356]
THLE RICTOR
Mean 20.3
Standard deviation 7.9
Values 26 15
[357]
liver RICTOR
Mean 27.1
Standard deviation 8.5
Values 24 35 17 33
[358]
ref_hepatocyte GAB2
Mean 1.62
Standard deviation 1.7
Values 1.2 1.9 4.5 0.25 0.31
[359]
HepG2 GAB2
Mean 10.6
Standard deviation 4.9
Values 14 7.1
[360]
HepG2.C3A GAB2
Mean 8.12
Standard deviation 3.2
Values 10 5.9
[361]
HuH.7 GAB2
Mean 9.24
Standard deviation 2.5
Values 9.6 12 6.6
[362]
SNU475 GAB2
Mean 5.63
Standard deviation 0.73
Values 6.1 5.1
[363]
THLE GAB2
Mean 6.7
Standard deviation 0.57
Values 7.1 6.3
[364]
liver GAB2
Mean 3.35
Standard deviation 1.3
Values 2.8 4.2 1.8 4.6
[365]
ref_hepatocyte FOXO4
Mean 1.56
Standard deviation 0.85
Values 2.8 1.6 0.42 1.7 1.3
[366]
HepG2 FOXO4
Mean 5.71
Standard deviation 1.3
Values 6.6 4.8
[367]
HepG2.C3A FOXO4
Mean 6.69
Standard deviation 3.6
Values 9.2 4.2
[368]
HuH.7 FOXO4
Mean 5.72
Standard deviation 1.5
Values 5.1 7.5 4.6
[369]
SNU475 FOXO4
Mean 3.21
Standard deviation 1.1
Values 4 2.4
[370]
THLE FOXO4
Mean 4.17
Standard deviation 0.02
Values 4.2 4.2
[371]
liver FOXO4
Mean 1.37
Standard deviation 1.1
Values 0.54 2 0.33 2.6
[372]
ref_hepatocyte ESR1
Mean 1.54
Standard deviation 2.3
Values 0 0.17 0 2.2 5.3
[373]
HepG2 ESR1
Mean 0.0215
Standard deviation 0.018
Values 0.034 0.0086
[374]
HepG2.C3A ESR1
Mean 0
Standard deviation 0
Values 0 0
[375]
HuH.7 ESR1
Mean 0.0525
Standard deviation 0.047
Values 0.11 0.032 0.019
[376]
SNU475 ESR1
Mean 0.157
Standard deviation 0.14
Values 0.06 0.25
[377]
THLE ESR1
Mean 0.0367
Standard deviation 0.0067
Values 0.041 0.032
[378]
liver ESR1
Mean 11.5
Standard deviation 7
Values 7.2 11 6.1 22
[379]
ref_hepatocyte FGFR2
Mean 1.34
Standard deviation 1.4
Values 0.47 0.46 0.084 2.4 3.2
[380]
HepG2 FGFR2
Mean 0.519
Standard deviation 0.3
Values 0.3 0.73
[381]
HepG2.C3A FGFR2
Mean 1.07
Standard deviation 0.3
Values 0.86 1.3
[382]
HuH.7 FGFR2
Mean 15.7
Standard deviation 0.71
Values 16 15 16
[383]
SNU475 FGFR2
Mean 6.74
Standard deviation 6.4
Values 11 2.2
[384]
THLE FGFR2
Mean 0.263
Standard deviation 0.0039
Values 0.27 0.26
[385]
liver FGFR2
Mean 20.4
Standard deviation 8
Values 18 19 13 32
[386]
ref_hepatocyte NRG1
Mean 1.2
Standard deviation 1
Values 0 1 2.8 1.5 0.74
[387]
HepG2 NRG1
Mean 3.35
Standard deviation 2.7
Values 1.4 5.3
[388]
HepG2.C3A NRG1
Mean 0.0424
Standard deviation 0.046
Values 0.0097 0.075
[389]
HuH.7 NRG1
Mean 0.302
Standard deviation 0.17
Values 0.16 0.49 0.25
[390]
SNU475 NRG1
Mean 9.16
Standard deviation 3.3
Values 12 6.8
[391]
THLE NRG1
Mean 0.0576
Standard deviation 0.031
Values 0.035 0.08
[392]
liver NRG1
Mean 2.92
Standard deviation 2.1
Values 1.2 5.5 3.6 1.2
[393]
ref_hepatocyte FRS2
Mean 1.15
Standard deviation 0.48
Values 1.3 1.9 0.69 0.74 1.2
[394]
HepG2 FRS2
Mean 6.18
Standard deviation 3
Values 4 8.3
[395]
HepG2.C3A FRS2
Mean 11.7
Standard deviation 4
Values 8.9 15
[396]
HuH.7 FRS2
Mean 15.9
Standard deviation 4.9
Values 16 21 11
[397]
SNU475 FRS2
Mean 15.7
Standard deviation 0.35
Values 16 15
[398]
THLE FRS2
Mean 13.6
Standard deviation 0.96
Values 14 13
[399]
liver FRS2
Mean 16.5
Standard deviation 3.3
Values 18 20 13 15
[400]
ref_hepatocyte STRN
Mean 1.09
Standard deviation 0.66
Values 1 1.8 1.7 0.36 0.54
[401]
HepG2 STRN
Mean 9.37
Standard deviation 2.4
Values 7.7 11
[402]
HepG2.C3A STRN
Mean 16.3
Standard deviation 1.3
Values 15 17
[403]
HuH.7 STRN
Mean 12
Standard deviation 3.1
Values 14 14 8.4
[404]
SNU475 STRN
Mean 20
Standard deviation 0.35
Values 20 20
[405]
THLE STRN
Mean 20.8
Standard deviation 0.87
Values 20 21
[406]
liver STRN
Mean 11.5
Standard deviation 5
Values 9.4 16 5.4 15
[407]
ref_hepatocyte NR4A1
Mean 0.973
Standard deviation 0.84
Values 0.53 0.14 1.1 2.3 0.73
[408]
HepG2 NR4A1
Mean 4.99
Standard deviation 1.2
Values 5.9 4.1
[409]
HepG2.C3A NR4A1
Mean 6.51
Standard deviation 3.5
Values 9 4
[410]
HuH.7 NR4A1
Mean 6.85
Standard deviation 0.31
Values 7 6.5 7.1
[411]
SNU475 NR4A1
Mean 1.97
Standard deviation 1.2
Values 1.1 2.8
[412]
THLE NR4A1
Mean 4.73
Standard deviation 1.4
Values 5.7 3.7
[413]
liver NR4A1
Mean 1.99
Standard deviation 2
Values 5 0.9 1.2 0.85
[414]
ref_hepatocyte BTC
Mean 0.915
Standard deviation 1.9
Values 0 4.4 0.079 0 0.12
[415]
HepG2 BTC
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[416]
HepG2.C3A BTC
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[417]
HuH.7 BTC
Mean 0.087
Standard deviation 0.09
Values 0.066 0.19 0.0094
[418]
SNU475 BTC
Mean 0.229
Standard deviation 0.03
Values 0.25 0.21
[419]
THLE BTC
Mean 0.251
Standard deviation 0.13
Values 0.34 0.16
[420]
liver BTC
Mean 0.172
Standard deviation 0.058
Values 0.21 0.23 0.1 0.15
[421]
ref_hepatocyte FGFR1
Mean 0.81
Standard deviation 0.63
Values 1.2 0.49 1.6 0.06 0.62
[422]
HepG2 FGFR1
Mean 42.7
Standard deviation 4
Values 40 46
[423]
HepG2.C3A FGFR1
Mean 11.8
Standard deviation 3.5
Values 9.3 14
[424]
HuH.7 FGFR1
Mean 35.6
Standard deviation 13
Values 43 20 43
[425]
SNU475 FGFR1
Mean 49.5
Standard deviation 1.4
Values 50 49
[426]
THLE FGFR1
Mean 33.4
Standard deviation 3.3
Values 36 31
[427]
liver FGFR1
Mean 3.64
Standard deviation 0.67
Values 3 4.2 3.2 4.3
[428]
ref_hepatocyte GAB1
Mean 0.787
Standard deviation 0.67
Values 2 0.61 0.33 0.38 0.66
[429]
HepG2 GAB1
Mean 4.28
Standard deviation 2.2
Values 2.8 5.8
[430]
HepG2.C3A GAB1
Mean 8.12
Standard deviation 2.3
Values 6.5 9.8
[431]
HuH.7 GAB1
Mean 8.48
Standard deviation 1.4
Values 10 8.1 7.3
[432]
SNU475 GAB1
Mean 5.52
Standard deviation 1.6
Values 6.6 4.4
[433]
THLE GAB1
Mean 5.62
Standard deviation 0.39
Values 5.9 5.3
[434]
liver GAB1
Mean 8.2
Standard deviation 2.5
Values 7.1 10 5.3 10
[435]
ref_hepatocyte PDGFB
Mean 0.738
Standard deviation 0.56
Values 0.25 1.4 1.3 0.23 0.54
[436]
HepG2 PDGFB
Mean 13.6
Standard deviation 5.2
Values 17 9.9
[437]
HepG2.C3A PDGFB
Mean 11
Standard deviation 4.6
Values 14 7.7
[438]
HuH.7 PDGFB
Mean 1.5
Standard deviation 0.44
Values 1.1 2 1.5
[439]
SNU475 PDGFB
Mean 1.42
Standard deviation 0.33
Values 1.7 1.2
[440]
THLE PDGFB
Mean 1.18
Standard deviation 0.022
Values 1.2 1.2
[441]
liver PDGFB
Mean 1.36
Standard deviation 0.68
Values 0.4 2 1.7 1.4
[442]
ref_hepatocyte NRG4
Mean 0.631
Standard deviation 0.35
Values 0 0.75 0.81 0.78 0.81
[443]
HepG2 NRG4
Mean 0.0816
Standard deviation 0.03
Values 0.1 0.06
[444]
HepG2.C3A NRG4
Mean 0.534
Standard deviation 0.042
Values 0.56 0.5
[445]
HuH.7 NRG4
Mean 0.494
Standard deviation 0.053
Values 0.43 0.51 0.53
[446]
SNU475 NRG4
Mean 1.41
Standard deviation 0.46
Values 1.7 1.1
[447]
THLE NRG4
Mean 0.345
Standard deviation 0.16
Values 0.46 0.23
[448]
liver NRG4
Mean 0.468
Standard deviation 0.12
Values 0.45 0.41 0.64 0.37
[449]
ref_hepatocyte FGF7
Mean 0.61
Standard deviation 0.64
Values 0 0.3 0.46 0.6 1.7
[450]
HepG2 FGF7
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[451]
HepG2.C3A FGF7
Mean 0.0248
Standard deviation 0.02
Values 0.039 0.011
[452]
HuH.7 FGF7
Mean 0
Standard deviation 0
Values 0 0 0
[453]
SNU475 FGF7
Mean 0.027
Standard deviation 0.012
Values 0.019 0.035
[454]
THLE FGF7
Mean 0.584
Standard deviation 0.1
Values 0.66 0.51
[455]
liver FGF7
Mean 0.317
Standard deviation 0.15
Values 0.28 0.31 0.51 0.16
[456]
ref_hepatocyte PDGFRA
Mean 0.51
Standard deviation 0.67
Values 0 0.018 1.5 0.93 0.11
[457]
HepG2 PDGFRA
Mean 0.0916
Standard deviation 0.016
Values 0.08 0.1
[458]
HepG2.C3A PDGFRA
Mean 0.0414
Standard deviation 0.017
Values 0.029 0.054
[459]
HuH.7 PDGFRA
Mean 7.89
Standard deviation 0.88
Values 8.3 8.5 6.9
[460]
SNU475 PDGFRA
Mean 1.35
Standard deviation 1.4
Values 0.38 2.3
[461]
THLE PDGFRA
Mean 38.6
Standard deviation 7.6
Values 33 44
[462]
liver PDGFRA
Mean 28.9
Standard deviation 13
Values 23 35 15 43
[463]
ref_hepatocyte PDGFRB
Mean 0.484
Standard deviation 0.34
Values 0.12 0.23 0.58 0.98 0.51
[464]
HepG2 PDGFRB
Mean 2.63
Standard deviation 0.88
Values 2 3.3
[465]
HepG2.C3A PDGFRB
Mean 3.08
Standard deviation 0.099
Values 3 3.2
[466]
HuH.7 PDGFRB
Mean 0.54
Standard deviation 0.088
Values 0.61 0.57 0.44
[467]
SNU475 PDGFRB
Mean 3.21
Standard deviation 0.1
Values 3.1 3.3
[468]
THLE PDGFRB
Mean 5.3
Standard deviation 0.27
Values 5.1 5.5
[469]
liver PDGFRB
Mean 7.32
Standard deviation 2
Values 6.9 6.3 5.8 10
[470]
ref_hepatocyte VAV1
Mean 0.469
Standard deviation 0.4
Values 0 0.2 0.63 0.48 1
[471]
HepG2 VAV1
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[472]
HepG2.C3A VAV1
Mean 0.0726
Standard deviation 0.034
Values 0.049 0.097
[473]
HuH.7 VAV1
Mean 0.0213
Standard deviation 0.0061
Values 0.016 0.019 0.028
[474]
SNU475 VAV1
Mean 0.0127
Standard deviation 0.018
Values 0 0.025
[475]
THLE VAV1
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[476]
liver VAV1
Mean 1.51
Standard deviation 0.9
Values 0.75 1.8 0.82 2.6
[477]
ref_hepatocyte PIK3R3
Mean 0.405
Standard deviation 0.3
Values 0.52 0.81 0.47 0.078 0.15
[478]
HepG2 PIK3R3
Mean 2.95
Standard deviation 2.5
Values 1.2 4.7
[479]
HepG2.C3A PIK3R3
Mean 2.65
Standard deviation 1.6
Values 1.5 3.8
[480]
HuH.7 PIK3R3
Mean 4.56
Standard deviation 1.3
Values 5.7 3.1 5
[481]
SNU475 PIK3R3
Mean 6.68
Standard deviation 0.22
Values 6.5 6.8
[482]
THLE PIK3R3
Mean 3.8
Standard deviation 0.9
Values 3.2 4.4
[483]
liver PIK3R3
Mean 3.68
Standard deviation 0.27
Values 3.7 3.8 3.3 4
[484]
ref_hepatocyte CD86
Mean 0.389
Standard deviation 0.38
Values 0 0 0.61 0.48 0.85
[485]
HepG2 CD86
Mean 0
Standard deviation 0
Values 0 0
[486]
HepG2.C3A CD86
Mean 0
Standard deviation 0
Values 0 0
[487]
HuH.7 CD86
Mean 0.0281
Standard deviation 0.02
Values 0.049 0.026 0.0094
[488]
SNU475 CD86
Mean 0.0418
Standard deviation 0.02
Values 0.028 0.056
[489]
THLE CD86
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[490]
liver CD86
Mean 1.41
Standard deviation 0.3
Values 1.2 1.9 1.2 1.3
[491]
ref_hepatocyte AKT3
Mean 0.387
Standard deviation 0.32
Values 0 0.53 0.83 0.16 0.41
[492]
HepG2 AKT3
Mean 0.238
Standard deviation 0.15
Values 0.34 0.13
[493]
HepG2.C3A AKT3
Mean 0.036
Standard deviation 0.0097
Values 0.029 0.043
[494]
HuH.7 AKT3
Mean 0.0557
Standard deviation 0.031
Values 0.049 0.09 0.028
[495]
SNU475 AKT3
Mean 40.8
Standard deviation 10
Values 48 34
[496]
THLE AKT3
Mean 22.1
Standard deviation 4.4
Values 25 19
[497]
liver AKT3
Mean 6.71
Standard deviation 4.9
Values 2.8 12 2.3 9.4
[498]
ref_hepatocyte LCK
Mean 0.319
Standard deviation 0.43
Values 0.11 0 0.49 0 0.99
[499]
HepG2 LCK
Mean 4.84
Standard deviation 4.4
Values 8 1.7
[500]
HepG2.C3A LCK
Mean 4.55
Standard deviation 0.16
Values 4.4 4.7
[501]
HuH.7 LCK
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[502]
SNU475 LCK
Mean 0.0173
Standard deviation 0.011
Values 0.0093 0.025
[503]
THLE LCK
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[504]
liver LCK
Mean 1.07
Standard deviation 0.51
Values 1.2 0.49 1.7 0.91
[505]
ref_hepatocyte KL
Mean 0.258
Standard deviation 0.29
Values 0 0 0.4 0.2 0.69
[506]
HepG2 KL
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[507]
HepG2.C3A KL
Mean 0
Standard deviation 0
Values 0 0
[508]
HuH.7 KL
Mean 0
Standard deviation 0
Values 0 0 0
[509]
SNU475 KL
Mean 0.181
Standard deviation 0.026
Values 0.2 0.16
[510]
THLE KL
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[511]
liver KL
Mean 0.436
Standard deviation 0.32
Values 0.38 0.31 0.15 0.9
[512]
ref_hepatocyte FGF5
Mean 0.241
Standard deviation 0.27
Values 0.042 0.036 0.09 0.64 0.4
[513]
HepG2 FGF5
Mean 0.268
Standard deviation 0.022
Values 0.25 0.28
[514]
HepG2.C3A FGF5
Mean 0.596
Standard deviation 0.024
Values 0.61 0.58
[515]
HuH.7 FGF5
Mean 0.543
Standard deviation 0.15
Values 0.62 0.65 0.37
[516]
SNU475 FGF5
Mean 1.24
Standard deviation 0.35
Values 0.99 1.5
[517]
THLE FGF5
Mean 1.11
Standard deviation 0.17
Values 0.99 1.2
[518]
liver FGF5
Mean 3.01
Standard deviation 1.5
Values 2.3 4.5 1.2 4.1
[519]
ref_hepatocyte EREG
Mean 0.24
Standard deviation 0.13
Values 0.3 0.18 0.15 0.13 0.45
[520]
HepG2 EREG
Mean 1.79
Standard deviation 1.2
Values 2.6 0.95
[521]
HepG2.C3A EREG
Mean 1.51
Standard deviation 1
Values 0.81 2.2
[522]
HuH.7 EREG
Mean 0.068
Standard deviation 0.032
Values 0.033 0.096 0.075
[523]
SNU475 EREG
Mean 0.149
Standard deviation 0.12
Values 0.065 0.23
[524]
THLE EREG
Mean 6.34
Standard deviation 2.2
Values 7.9 4.8
[525]
liver EREG
Mean 0.123
Standard deviation 0.11
Values 0 0.13 0.26 0.11
[526]
ref_hepatocyte FGF1
Mean 0.126
Standard deviation 0.27
Values 0 0.6 0 0 0.024
[527]
HepG2 FGF1
Mean 0.0408
Standard deviation 0.04
Values 0.069 0.013
[528]
HepG2.C3A FGF1
Mean 0.0628
Standard deviation 0.048
Values 0.029 0.097
[529]
HuH.7 FGF1
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[530]
SNU475 FGF1
Mean 0.346
Standard deviation 0.077
Values 0.29 0.4
[531]
THLE FGF1
Mean 1.16
Standard deviation 0.44
Values 0.85 1.5
[532]
liver FGF1
Mean 0.184
Standard deviation 0.042
Values 0.14 0.21 0.15 0.23
[533]
ref_hepatocyte FGF19
Mean 0.122
Standard deviation 0.27
Values 0 0 0.61 0 0
[534]
HepG2 FGF19
Mean 0.0644
Standard deviation 0.0062
Values 0.069 0.06
[535]
HepG2.C3A FGF19
Mean 0.128
Standard deviation 0.0016
Values 0.13 0.13
[536]
HuH.7 FGF19
Mean 13.1
Standard deviation 3.4
Values 11 17 12
[537]
SNU475 FGF19
Mean 0.397
Standard deviation 0.15
Values 0.51 0.29
[538]
THLE FGF19
Mean 0.0402
Standard deviation 0.027
Values 0.059 0.021
[539]
liver FGF19
Mean 0
Standard deviation 0
Values 0 0 0 0
[540]
ref_hepatocyte KITLG
Mean 0.0988
Standard deviation 0.16
Values 0.024 0.39 0 0.052 0.033
[541]
HepG2 KITLG
Mean 9.5
Standard deviation 3.6
Values 6.9 12
[542]
HepG2.C3A KITLG
Mean 0.616
Standard deviation 0.27
Values 0.43 0.8
[543]
HuH.7 KITLG
Mean 31.3
Standard deviation 8.5
Values 41 24 29
[544]
SNU475 KITLG
Mean 19.3
Standard deviation 0.86
Values 20 19
[545]
THLE KITLG
Mean 6.16
Standard deviation 2
Values 7.6 4.7
[546]
liver KITLG
Mean 1.15
Standard deviation 0.074
Values 1.2 1.2 1.1 1.1
[547]
ref_hepatocyte CD28
Mean 0.0933
Standard deviation 0.1
Values 0.14 0 0 0.086 0.24
[548]
HepG2 CD28
Mean 0.0129
Standard deviation 0.018
Values 0 0.026
[549]
HepG2.C3A CD28
Mean 0.0209
Standard deviation 0.016
Values 0.0097 0.032
[550]
HuH.7 CD28
Mean 0.0205
Standard deviation 0.023
Values 0.0082 0.0064 0.047
[551]
SNU475 CD28
Mean 0.0338
Standard deviation 0.0047
Values 0.037 0.03
[552]
THLE CD28
Mean 0.0364
Standard deviation 0.0012
Values 0.035 0.037
[553]
liver CD28
Mean 0.288
Standard deviation 0.19
Values 0.094 0.27 0.23 0.56
[554]
ref_hepatocyte KIT
Mean 0.0798
Standard deviation 0.075
Values 0 0 0.15 0.1 0.15
[555]
HepG2 KIT
Mean 0.0222
Standard deviation 0.025
Values 0.04 0.0043
[556]
HepG2.C3A KIT
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[557]
HuH.7 KIT
Mean 0
Standard deviation 0
Values 0 0 0
[558]
SNU475 KIT
Mean 0.83
Standard deviation 0.64
Values 1.3 0.38
[559]
THLE KIT
Mean 0.0201
Standard deviation 0.013
Values 0.03 0.011
[560]
liver KIT
Mean 1.41
Standard deviation 1.3
Values 0.21 3 1.9 0.54
[561]
ref_hepatocyte CD19
Mean 0.0626
Standard deviation 0.11
Values 0 0 0 0.069 0.24
[562]
HepG2 CD19
Mean 0.596
Standard deviation 0.49
Values 0.94 0.25
[563]
HepG2.C3A CD19
Mean 1.72
Standard deviation 0.22
Values 1.9 1.6
[564]
HuH.7 CD19
Mean 0.0579
Standard deviation 0.035
Values 0.049 0.096 0.028
[565]
SNU475 CD19
Mean 0.0416
Standard deviation 0.013
Values 0.032 0.051
[566]
THLE CD19
Mean 0
Standard deviation 0
Values 0 0
[567]
liver CD19
Mean 0.186
Standard deviation 0.21
Values 0.45 0 0.26 0.04
[568]
ref_hepatocyte CD80
Mean 0.0435
Standard deviation 0.06
Values 0 0 0 0.1 0.11
[569]
HepG2 CD80
Mean 0
Standard deviation 0
Values 0 0
[570]
HepG2.C3A CD80
Mean 0
Standard deviation 0
Values 0 0
[571]
HuH.7 CD80
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[572]
SNU475 CD80
Mean 0.0359
Standard deviation 0.015
Values 0.046 0.025
[573]
THLE CD80
Mean 0.0192
Standard deviation 0.01
Values 0.012 0.027
[574]
liver CD80
Mean 0.381
Standard deviation 0.28
Values 0.12 0.64 0.15 0.61
[575]
ref_hepatocyte FLT3
Mean 0.0374
Standard deviation 0.084
Values 0 0 0 0 0.19
[576]
HepG2 FLT3
Mean 0
Standard deviation 0
Values 0 0
[577]
HepG2.C3A FLT3
Mean 0
Standard deviation 0
Values 0 0
[578]
HuH.7 FLT3
Mean 0.00625
Standard deviation 0.011
Values 0 0 0.019
[579]
SNU475 FLT3
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[580]
THLE FLT3
Mean 0
Standard deviation 0
Values 0 0
[581]
liver FLT3
Mean 0.402
Standard deviation 0.15
Values 0.21 0.44 0.39 0.57
[582]
ref_hepatocyte ESR2
Mean 0.0345
Standard deviation 0.077
Values 0 0 0 0.17 0
[583]
HepG2 ESR2
Mean 0.0515
Standard deviation 0.024
Values 0.034 0.069
[584]
HepG2.C3A ESR2
Mean 0.0593
Standard deviation 0.054
Values 0.097 0.021
[585]
HuH.7 ESR2
Mean 0.0579
Standard deviation 0.035
Values 0.049 0.096 0.028
[586]
SNU475 ESR2
Mean 0.0984
Standard deviation 0.047
Values 0.065 0.13
[587]
THLE ESR2
Mean 0.118
Standard deviation 0.00092
Values 0.12 0.12
[588]
liver ESR2
Mean 0.283
Standard deviation 0.18
Values 0.24 0.2 0.15 0.54
[589]
ref_hepatocyte TRAT1
Mean 0.0293
Standard deviation 0.065
Values 0 0 0 0 0.15
[590]
HepG2 TRAT1
Mean 0
Standard deviation 0
Values 0 0
[591]
HepG2.C3A TRAT1
Mean 0
Standard deviation 0
Values 0 0
[592]
HuH.7 TRAT1
Mean 0
Standard deviation 0
Values 0 0 0
[593]
SNU475 TRAT1
Mean 0
Standard deviation 0
Values 0 0
[594]
THLE TRAT1
Mean 0
Standard deviation 0
Values 0 0
[595]
liver TRAT1
Mean 0.287
Standard deviation 0.051
Values 0.33 0.26 0.23 0.33
[596]
ref_hepatocyte ICOS
Mean 0.0282
Standard deviation 0.041
Values 0 0 0 0.052 0.089
[597]
HepG2 ICOS
Mean 0
Standard deviation 0
Values 0 0
[598]
HepG2.C3A ICOS
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[599]
HuH.7 ICOS
Mean 0
Standard deviation 0
Values 0 0 0
[600]
SNU475 ICOS
Mean 0
Standard deviation 0
Values 0 0
[601]
THLE ICOS
Mean 0
Standard deviation 0
Values 0 0
[602]
liver ICOS
Mean 0.0272
Standard deviation 0.033
Values 0 0.043 0 0.066
[603]
ref_hepatocyte HGF
Mean 0.0217
Standard deviation 0.03
Values 0 0 0 0.052 0.057
[604]
HepG2 HGF
Mean 0
Standard deviation 0
Values 0 0
[605]
HepG2.C3A HGF
Mean 0
Standard deviation 0
Values 0 0
[606]
HuH.7 HGF
Mean 0.0131
Standard deviation 0.017
Values 0.033 0.0064 0
[607]
SNU475 HGF
Mean 0.963
Standard deviation 0.42
Values 1.3 0.67
[608]
THLE HGF
Mean 0.138
Standard deviation 0.061
Values 0.095 0.18
[609]
liver HGF
Mean 14.7
Standard deviation 7.2
Values 9.2 24 9.5 16
[610]
ref_hepatocyte FGF8
Mean 0.0195
Standard deviation 0.044
Values 0 0 0 0 0.098
[611]
HepG2 FGF8
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[612]
HepG2.C3A FGF8
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[613]
HuH.7 FGF8
Mean 0.105
Standard deviation 0.073
Values 0.19 0.051 0.075
[614]
SNU475 FGF8
Mean 0.00949
Standard deviation 0.0063
Values 0.014 0.0051
[615]
THLE FGF8
Mean 0
Standard deviation 0
Values 0 0
[616]
liver FGF8
Mean 0.18
Standard deviation 0.14
Values 0.047 0.34 0.077 0.25
[617]
ref_hepatocyte FGF18
Mean 0.0138
Standard deviation 0.031
Values 0 0 0 0.069 0
[618]
HepG2 FGF18
Mean 0.105
Standard deviation 0.039
Values 0.13 0.077
[619]
HepG2.C3A FGF18
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[620]
HuH.7 FGF18
Mean 0.0232
Standard deviation 0.02
Values 0 0.032 0.037
[621]
SNU475 FGF18
Mean 0.0388
Standard deviation 0.0024
Values 0.037 0.041
[622]
THLE FGF18
Mean 0.0657
Standard deviation 0.033
Values 0.089 0.043
[623]
liver FGF18
Mean 0.0294
Standard deviation 0.0072
Values 0.024 0.029 0.026 0.04
[624]
ref_hepatocyte FGF9
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[625]
HepG2 FGF9
Mean 0.0687
Standard deviation 9.1e-05
Values 0.069 0.069
[626]
HepG2.C3A FGF9
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[627]
HuH.7 FGF9
Mean 0
Standard deviation 0
Values 0 0 0
[628]
SNU475 FGF9
Mean 0.0822
Standard deviation 0.08
Values 0.14 0.025
[629]
THLE FGF9
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[630]
liver FGF9
Mean 0.00993
Standard deviation 0.02
Values 0 0 0 0.04
[631]
ref_hepatocyte EGF
Mean 0.00415
Standard deviation 0.0093
Values 0 0.021 0 0 0
[632]
HepG2 EGF
Mean 0.0358
Standard deviation 0.014
Values 0.046 0.026
[633]
HepG2.C3A EGF
Mean 0.11
Standard deviation 0.087
Values 0.049 0.17
[634]
HuH.7 EGF
Mean 1.29
Standard deviation 0.44
Values 0.97 1.8 1.1
[635]
SNU475 EGF
Mean 3.97
Standard deviation 0.5
Values 4.3 3.6
[636]
THLE EGF
Mean 0.743
Standard deviation 0.02
Values 0.76 0.73
[637]
liver EGF
Mean 0.0176
Standard deviation 0.027
Values 0 0.057 0 0.013
[638]
ref_hepatocyte FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[639]
HepG2 FGF3
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[640]
HepG2.C3A FGF3
Mean 0
Standard deviation 0
Values 0 0
[641]
HuH.7 FGF3
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[642]
SNU475 FGF3
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[643]
THLE FGF3
Mean 0
Standard deviation 0
Values 0 0
[644]
liver FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0
[645]
ref_hepatocyte FGF20
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[646]
HepG2 FGF20
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[647]
HepG2.C3A FGF20
Mean 0
Standard deviation 0
Values 0 0
[648]
HuH.7 FGF20
Mean 0
Standard deviation 0
Values 0 0 0
[649]
SNU475 FGF20
Mean 0.00485
Standard deviation 0.0003
Values 0.0046 0.0051
[650]
THLE FGF20
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[651]
liver FGF20
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[652]
ref_hepatocyte FGF23
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[653]
HepG2 FGF23
Mean 0
Standard deviation 0
Values 0 0
[654]
HepG2.C3A FGF23
Mean 0
Standard deviation 0
Values 0 0
[655]
HuH.7 FGF23
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[656]
SNU475 FGF23
Mean 0
Standard deviation 0
Values 0 0
[657]
THLE FGF23
Mean 0
Standard deviation 0
Values 0 0
[658]
liver FGF23
Mean 0.68
Standard deviation 0.31
Values 0.59 0.67 1.1 0.36
[659]
ref_hepatocyte FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[660]
HepG2 FGF22
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[661]
HepG2.C3A FGF22
Mean 0
Standard deviation 0
Values 0 0
[662]
HuH.7 FGF22
Mean 0.00625
Standard deviation 0.011
Values 0 0 0.019
[663]
SNU475 FGF22
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[664]
THLE FGF22
Mean 0
Standard deviation 0
Values 0 0
[665]
liver FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0
[666]
ref_hepatocyte FGF10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[667]
HepG2 FGF10
Mean 0
Standard deviation 0
Values 0 0
[668]
HepG2.C3A FGF10
Mean 0
Standard deviation 0
Values 0 0
[669]
HuH.7 FGF10
Mean 0
Standard deviation 0
Values 0 0 0
[670]
SNU475 FGF10
Mean 0
Standard deviation 0
Values 0 0
[671]
THLE FGF10
Mean 0
Standard deviation 0
Values 0 0
[672]
liver FGF10
Mean 0.0234
Standard deviation 0.038
Values 0 0.014 0 0.079
[673]
ref_hepatocyte FGF17
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[674]
HepG2 FGF17
Mean 0.398
Standard deviation 0.15
Values 0.5 0.29
[675]
HepG2.C3A FGF17
Mean 1.23
Standard deviation 1.1
Values 2 0.46
[676]
HuH.7 FGF17
Mean 0.183
Standard deviation 0.2
Values 0.074 0.41 0.066
[677]
SNU475 FGF17
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[678]
THLE FGF17
Mean 0.0228
Standard deviation 0.0096
Values 0.03 0.016
[679]
liver FGF17
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[680]
ref_hepatocyte NRG3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[681]
HepG2 NRG3
Mean 0
Standard deviation 0
Values 0 0
[682]
HepG2.C3A NRG3
Mean 0
Standard deviation 0
Values 0 0
[683]
HuH.7 NRG3
Mean 0.376
Standard deviation 0.32
Values 0.18 0.75 0.2
[684]
SNU475 NRG3
Mean 0
Standard deviation 0
Values 0 0
[685]
THLE NRG3
Mean 0
Standard deviation 0
Values 0 0
[686]
liver NRG3
Mean 0.222
Standard deviation 0.073
Values 0.28 0.2 0.13 0.28
[687]
ref_hepatocyte FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[688]
HepG2 FGF4
Mean 0
Standard deviation 0
Values 0 0
[689]
HepG2.C3A FGF4
Mean 0
Standard deviation 0
Values 0 0
[690]
HuH.7 FGF4
Mean 0
Standard deviation 0
Values 0 0 0
[691]
SNU475 FGF4
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[692]
THLE FGF4
Mean 0
Standard deviation 0
Values 0 0
[693]
liver FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0
[694]
ref_hepatocyte FGF16
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[695]
HepG2 FGF16
Mean 0
Standard deviation 0
Values 0 0
[696]
HepG2.C3A FGF16
Mean 0
Standard deviation 0
Values 0 0
[697]
HuH.7 FGF16
Mean 0
Standard deviation 0
Values 0 0 0
[698]
SNU475 FGF16
Mean 0
Standard deviation 0
Values 0 0
[699]
THLE FGF16
Mean 0
Standard deviation 0
Values 0 0
[700]
liver FGF16
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[701]
ref_hepatocyte ERBB4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[702]
HepG2 ERBB4
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[703]
HepG2.C3A ERBB4
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[704]
HuH.7 ERBB4
Mean 0.136
Standard deviation 0.15
Values 0.098 0.3 0.0094
[705]
SNU475 ERBB4
Mean 0.0217
Standard deviation 0.0021
Values 0.023 0.02
[706]
THLE ERBB4
Mean 0.0662
Standard deviation 0.027
Values 0.047 0.085
[707]
liver ERBB4
Mean 0.308
Standard deviation 0.33
Values 0.14 0.29 0.026 0.78
[708]
ref_hepatocyte EPGN
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[709]
HepG2 EPGN
Mean 0.0544
Standard deviation 0.028
Values 0.074 0.034
[710]
HepG2.C3A EPGN
Mean 0.0501
Standard deviation 0.025
Values 0.068 0.032
[711]
HuH.7 EPGN
Mean 0.127
Standard deviation 0.084
Values 0.082 0.22 0.075
[712]
SNU475 EPGN
Mean 0.503
Standard deviation 0.27
Values 0.31 0.69
[713]
THLE EPGN
Mean 4.76
Standard deviation 1.2
Values 5.6 3.9
[714]
liver EPGN
Mean 0.161
Standard deviation 0.11
Values 0.12 0.17 0.051 0.3
[715]
ref_hepatocyte FGF6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[716]
HepG2 FGF6
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[717]
HepG2.C3A FGF6
Mean 0
Standard deviation 0
Values 0 0
[718]
HuH.7 FGF6
Mean 0
Standard deviation 0
Values 0 0 0
[719]
SNU475 FGF6
Mean 0
Standard deviation 0
Values 0 0
[720]
THLE FGF6
Mean 0
Standard deviation 0
Values 0 0
[721]
liver FGF6
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[722]
ref_hepatocyte NRG2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[723]
HepG2 NRG2
Mean 0.0236
Standard deviation 0.015
Values 0.034 0.013
[724]
HepG2.C3A NRG2
Mean 0
Standard deviation 0
Values 0 0
[725]
HuH.7 NRG2
Mean 0
Standard deviation 0
Values 0 0 0
[726]
SNU475 NRG2
Mean 0.181
Standard deviation 0.12
Values 0.093 0.27
[727]
THLE NRG2
Mean 0.79
Standard deviation 0.23
Values 0.63 0.95
[728]
liver NRG2
Mean 0.0321
Standard deviation 0.024
Values 0.047 0.029 0 0.053
[729]
ref_hepatocyte FOXO6
Missing
[730]
HepG2 FOXO6
Missing
[731]
HepG2.C3A FOXO6
Missing
[732]
HuH.7 FOXO6
Missing
[733]
SNU475 FOXO6
Missing
[734]
THLE FOXO6
Missing
[735]
liver FOXO6
Missing