REACTOME_PHYSIOLOGICAL_FACTORS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 NPR2 Atrial natriuretic peptide receptor 2 [1] -4.15[2] -2.23[3] -2.98[4] -2.48[5] -1.56[6] -2.86[7]
2 WWTR1 WW domain-containing transcription regulator protein 1 [8] 0.79[9] 0.35[10] -0.81[11] 0.72[12] -0.23[13] -1.74[14]
3 HIPK2 Homeodomain-interacting protein kinase 2 [15] 0.89[16] 1.19[17] 0.36[18] 1.14[19] 0.98[20] 1.96[21]
4 GATA4 Transcription factor GATA-4 [22] -0.32[23] -0.40[24] 0.85[25] -2.81[26] -0.13[27] -1.89[28]
5 HIPK1 Homeodomain-interacting protein kinase 1 [29] 0.47[30] 0.47[31] 1.24[32] 0.62[33] 0.21[34] -0.23[35]
6 KAT2B Histone acetyltransferase KAT2B [36] -3.15[37] -4.30[38] -2.10[39] -1.65[40] -1.49[41] -0.69[42]
7 NPR1 Atrial natriuretic peptide receptor 1 [43] -3.87[44] -4.83[45] -1.99[46] -2.81[47] 2.46[48] 2.81[49]
8 NKX2-5 Homeobox protein Nkx-2.5 [50] 0.95[51] -1.60[52] -7.84[53] -5.43[54] 3.39[55] [56]
9 NPPA Natriuretic peptides A [57] -1.66[58] 3.34[59] -0.86[60] -1.30[61] -2.71[62] -3.09[63]
10 TBX5 T-box transcription factor TBX5 [64] [65] [66] [67] -4.76[68] [69] [70]
11 CORIN Atrial natriuretic peptide-converting enzyme [71] 0.69[72] -1.05[73] 3.33[74] 1.03[75] 0.40[76] 1.83[77]
12 NPPC C-type natriuretic peptide [78] [79] [80] [81] [82] [83] [84]
[1]
ref_hepatocyte NPR2
Mean 5.36
Standard deviation 7
Values 0.34 4 18 2.9 2
[2]
HepG2 NPR2
Mean 1.43
Standard deviation 0.47
Values 1.1 1.8
[3]
HepG2.C3A NPR2
Mean 4.91
Standard deviation 0.29
Values 5.1 4.7
[4]
HuH.7 NPR2
Mean 3.15
Standard deviation 0.93
Values 2.5 4.2 2.7
[5]
SNU475 NPR2
Mean 5.31
Standard deviation 0.63
Values 5.8 4.9
[6]
THLE NPR2
Mean 13.5
Standard deviation 0.64
Values 13 14
[7]
liver NPR2
Mean 5.84
Standard deviation 2.4
Values 6.5 5.4 2.9 8.6
[8]
ref_hepatocyte WWTR1
Mean 5.02
Standard deviation 4.3
Values 12 3.8 5.4 1.2 2.6
[9]
HepG2 WWTR1
Mean 41.2
Standard deviation 0.072
Values 41 41
[10]
HepG2.C3A WWTR1
Mean 27.5
Standard deviation 7.8
Values 33 22
[11]
HuH.7 WWTR1
Mean 13.3
Standard deviation 1.5
Values 13 15 12
[12]
SNU475 WWTR1
Mean 45.7
Standard deviation 8.3
Values 52 40
[13]
THLE WWTR1
Mean 31.8
Standard deviation 6
Values 28 36
[14]
liver WWTR1
Mean 11.9
Standard deviation 2.9
Values 14 11 15 8.4
[15]
ref_hepatocyte HIPK2
Mean 4.12
Standard deviation 1.9
Values 6.3 5.4 4.4 1.7 2.8
[16]
HepG2 HIPK2
Mean 36.3
Standard deviation 11
Values 29 44
[17]
HepG2.C3A HIPK2
Mean 40.4
Standard deviation 2.3
Values 42 39
[18]
HuH.7 HIPK2
Mean 24.6
Standard deviation 9.8
Values 32 29 13
[19]
SNU475 HIPK2
Mean 50.1
Standard deviation 7.4
Values 55 45
[20]
THLE HIPK2
Mean 60.5
Standard deviation 7.6
Values 55 66
[21]
liver HIPK2
Mean 127
Standard deviation 19
Values 1.1e+02 1.3e+02 1.1e+02 1.5e+02
[22]
ref_hepatocyte GATA4
Mean 3.97
Standard deviation 2.3
Values 6.3 1 2.3 6 4.3
[23]
HepG2 GATA4
Mean 15.1
Standard deviation 1.5
Values 14 16
[24]
HepG2.C3A GATA4
Mean 12.9
Standard deviation 0.72
Values 13 12
[25]
HuH.7 GATA4
Mean 33.3
Standard deviation 6.5
Values 30 41 29
[26]
SNU475 GATA4
Mean 3.13
Standard deviation 0.12
Values 3.2 3
[27]
THLE GATA4
Mean 26.9
Standard deviation 1.1
Values 26 28
[28]
liver GATA4
Mean 8.47
Standard deviation 2.5
Values 12 6.8 9.2 6.2
[29]
ref_hepatocyte HIPK1
Mean 3.63
Standard deviation 1.7
Values 5.5 3.9 5 1.6 2.2
[30]
HepG2 HIPK1
Mean 23.8
Standard deviation 5.7
Values 20 28
[31]
HepG2.C3A HIPK1
Mean 21.6
Standard deviation 1.5
Values 21 23
[32]
HuH.7 HIPK1
Mean 39.7
Standard deviation 13
Values 46 48 25
[33]
SNU475 HIPK1
Mean 30.8
Standard deviation 0.34
Values 31 31
[34]
THLE HIPK1
Mean 31.2
Standard deviation 4.2
Values 28 34
[35]
liver HIPK1
Mean 24.5
Standard deviation 7.7
Values 20 31 16 31
[36]
ref_hepatocyte KAT2B
Mean 3.02
Standard deviation 2.4
Values 0.53 4.6 0.74 3.2 6.1
[37]
HepG2 KAT2B
Mean 1.62
Standard deviation 1.1
Values 0.84 2.4
[38]
HepG2.C3A KAT2B
Mean 0.662
Standard deviation 0.012
Values 0.67 0.65
[39]
HuH.7 KAT2B
Mean 3.28
Standard deviation 0.41
Values 2.8 3.6 3.4
[40]
SNU475 KAT2B
Mean 5.31
Standard deviation 1.3
Values 6.2 4.4
[41]
THLE KAT2B
Mean 7.98
Standard deviation 1.1
Values 7.2 8.8
[42]
liver KAT2B
Mean 14.8
Standard deviation 5
Values 19 17 7.6 16
[43]
ref_hepatocyte NPR1
Mean 0.161
Standard deviation 0.17
Values 0 0 0.24 0.4 0.16
[44]
HepG2 NPR1
Mean 0.0523
Standard deviation 0.031
Values 0.074 0.03
[45]
HepG2.C3A NPR1
Mean 0.0243
Standard deviation 0.034
Values 0.049 0
[46]
HuH.7 NPR1
Mean 0.187
Standard deviation 0.063
Values 0.25 0.13 0.18
[47]
SNU475 NPR1
Mean 0.126
Standard deviation 0.0079
Values 0.12 0.13
[48]
THLE NPR1
Mean 6.55
Standard deviation 0.4
Values 6.3 6.8
[49]
liver NPR1
Mean 8.95
Standard deviation 4.4
Values 3.5 11 7.6 13
[50]
ref_hepatocyte NKX2-5
Mean 0.136
Standard deviation 0.28
Values 0.64 0 0 0 0.041
[51]
HepG2 NKX2-5
Mean 1.24
Standard deviation 0.63
Values 1.7 0.8
[52]
HepG2.C3A NKX2-5
Mean 0.193
Standard deviation 0.12
Values 0.11 0.28
[53]
HuH.7 NKX2-5
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[54]
SNU475 NKX2-5
Mean 0.0173
Standard deviation 0.011
Values 0.0093 0.025
[55]
THLE NKX2-5
Mean 10.5
Standard deviation 1.6
Values 9.4 12
[56]
liver NKX2-5
Mean 0
Standard deviation 0
Values 0 0 0 0
[57]
ref_hepatocyte NPPA
Mean 0.0328
Standard deviation 0.073
Values 0 0 0 0.16 0
[58]
HepG2 NPPA
Mean 0.0494
Standard deviation 0.021
Values 0.034 0.064
[59]
HepG2.C3A NPPA
Mean 1.42
Standard deviation 0.87
Values 2 0.8
[60]
HuH.7 NPPA
Mean 0.0837
Standard deviation 0.043
Values 0.049 0.071 0.13
[61]
SNU475 NPPA
Mean 0.0732
Standard deviation 0.018
Values 0.06 0.086
[62]
THLE NPPA
Mean 0.0373
Standard deviation 0.023
Values 0.053 0.021
[63]
liver NPPA
Mean 0.0304
Standard deviation 0.043
Values 0.094 0.014 0 0.013
[64]
ref_hepatocyte TBX5
Mean 0.0228
Standard deviation 0.036
Values 0.033 0 0 0 0.081
[65]
HepG2 TBX5
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A TBX5
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 TBX5
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 TBX5
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[69]
THLE TBX5
Mean 0
Standard deviation 0
Values 0 0
[70]
liver TBX5
Mean 0
Standard deviation 0
Values 0 0 0 0
[71]
ref_hepatocyte CORIN
Mean 0.0117
Standard deviation 0.016
Values 0 0 0 0.026 0.033
[72]
HepG2 CORIN
Mean 0.0894
Standard deviation 0.013
Values 0.08 0.099
[73]
HepG2.C3A CORIN
Mean 0.0243
Standard deviation 0.034
Values 0.049 0
[74]
HuH.7 CORIN
Mean 0.543
Standard deviation 0.033
Values 0.55 0.51 0.57
[75]
SNU475 CORIN
Mean 0.132
Standard deviation 0.036
Values 0.11 0.16
[76]
THLE CORIN
Mean 0.114
Standard deviation 0.019
Values 0.1 0.13
[77]
liver CORIN
Mean 0.329
Standard deviation 0.22
Values 0.28 0.27 0.13 0.64
[78]
ref_hepatocyte NPPC
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 NPPC
Mean 0.0394
Standard deviation 0.05
Values 0.074 0.0043
[80]
HepG2.C3A NPPC
Mean 0.0394
Standard deviation 0.041
Values 0.068 0.011
[81]
HuH.7 NPPC
Mean 0.0197
Standard deviation 0.012
Values 0.0082 0.032 0.019
[82]
SNU475 NPPC
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[83]
THLE NPPC
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[84]
liver NPPC
Mean 0
Standard deviation 0
Values 0 0 0 0