REACTOME_PHOSPHORYLATION_OF_THE_APC_C Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ANAPC11 Anaphase-promoting complex subunit 11 [1] -1.97[2] -2.03[3] -2.42[4] -2.46[5] -2.59[6] -0.82[7]
2 CDC26 Anaphase-promoting complex subunit CDC26 [8] -2.91[9] -2.94[10] -2.94[11] -3.17[12] -2.79[13] -1.63[14]
3 UBE2E1 Ubiquitin-conjugating enzyme E2 E1 [15] -1.09[16] -1.36[17] -0.61[18] -0.63[19] -0.87[20] -2.23[21]
4 ANAPC16 Anaphase-promoting complex subunit 16 [22] 0.05[23] 0.25[24] -0.87[25] -0.57[26] -0.84[27] 1.12[28]
5 ANAPC5 Anaphase-promoting complex subunit 5 [29] 0.74[30] 0.90[31] 1.09[32] 0.19[33] 0.14[34] 1.29[35]
6 CDC27 Cell division cycle protein 27 homolog [36] 0.08[37] 0.41[38] -0.21[39] 1.04[40] 0.07[41] 0.73[42]
7 CDC16 Cell division cycle protein 16 homolog [43] -0.63[44] -0.91[45] -1.53[46] -0.57[47] -0.63[48] 0.45[49]
8 UBE2C Ubiquitin-conjugating enzyme E2 C [50] -0.37[51] -0.50[52] 0.30[53] -0.02[54] 0.37[55] -3.22[56]
9 UBE2S Ubiquitin-conjugating enzyme E2 S [57] 0.31[58] -0.62[59] 1.60[60] 0.82[61] 1.67[62] -2.01[63]
10 CCNB1 G2/mitotic-specific cyclin-B1 [64] 1.72[65] 1.44[66] 1.65[67] 1.46[68] 1.93[69] -1.77[70]
11 CDC23 Cell division cycle protein 23 homolog [71] 0.24[72] -0.07[73] 0.23[74] 0.88[75] 0.09[76] 0.77[77]
12 CDK1 Cyclin-dependent kinase 1 [78] 1.12[79] 2.67[80] 1.44[81] 2.12[82] 2.44[83] -1.89[84]
13 ANAPC7 Anaphase-promoting complex subunit 7 [85] 0.87[86] 0.76[87] 0.26[88] 0.75[89] 0.51[90] 0.76[91]
14 ANAPC2 Anaphase-promoting complex subunit 2 [92] 0.48[93] -0.60[94] 0.05[95] -0.11[96] -0.65[97] 0.62[98]
15 PLK1 Serine/threonine-protein kinase PLK1 [99] 2.36[100] 1.59[101] 1.48[102] 1.10[103] 1.63[104] -2.05[105]
16 ANAPC1 Anaphase-promoting complex subunit 1 [106] 2.28[107] 1.95[108] 1.87[109] 1.78[110] 1.29[111] 2.03[112]
17 ANAPC4 Anaphase-promoting complex subunit 4 [113] 0.06[114] 0.48[115] 0.84[116] 1.04[117] 0.01[118] 1.56[119]
18 UBE2D1 Ubiquitin-conjugating enzyme E2 D1 [120] 0.66[121] 1.02[122] 1.40[123] 1.37[124] 0.63[125] 1.08[126]
19 ANAPC10 Anaphase-promoting complex subunit 10 [127] -0.37[128] 0.01[129] -0.57[130] -0.37[131] -0.09[132] 0.70[133]
20 ANAPC15 Anaphase-promoting complex subunit 15 [134] [135] [136] [137] [138] [139] [140]
[1]
ref_hepatocyte ANAPC11
Mean 54.5
Standard deviation 27
Values 63 82 10 54 64
[2]
HepG2 ANAPC11
Mean 33.8
Standard deviation 7.4
Values 39 29
[3]
HepG2.C3A ANAPC11
Mean 40.9
Standard deviation 8.3
Values 35 47
[4]
HuH.7 ANAPC11
Mean 29.3
Standard deviation 14
Values 30 15 43
[5]
SNU475 ANAPC11
Mean 20.1
Standard deviation 5.4
Values 24 16
[6]
THLE ANAPC11
Mean 29.3
Standard deviation 0.86
Values 30 29
[7]
liver ANAPC11
Mean 29.4
Standard deviation 28
Values 60 5.9 47 5.7
[8]
ref_hepatocyte CDC26
Mean 30
Standard deviation 5.8
Values 24 31 34 37 24
[9]
HepG2 CDC26
Mean 9.65
Standard deviation 1.5
Values 8.6 11
[10]
HepG2.C3A CDC26
Mean 12
Standard deviation 3.9
Values 9.2 15
[11]
HuH.7 CDC26
Mean 11.2
Standard deviation 1.9
Values 10 10 13
[12]
SNU475 CDC26
Mean 6.75
Standard deviation 0.98
Values 7.4 6.1
[13]
THLE CDC26
Mean 14
Standard deviation 0.81
Values 13 15
[14]
liver CDC26
Mean 9.23
Standard deviation 6.7
Values 14 4.5 15 2.6
[15]
ref_hepatocyte UBE2E1
Mean 24.2
Standard deviation 20
Values 24 60 11 13 14
[16]
HepG2 UBE2E1
Mean 27.5
Standard deviation 0.51
Values 28 27
[17]
HepG2.C3A UBE2E1
Mean 29
Standard deviation 6
Values 25 33
[18]
HuH.7 UBE2E1
Mean 45.6
Standard deviation 10
Values 42 37 57
[19]
SNU475 UBE2E1
Mean 31.8
Standard deviation 1
Values 31 33
[20]
THLE UBE2E1
Mean 42.8
Standard deviation 1.4
Values 42 44
[21]
liver UBE2E1
Mean 4.91
Standard deviation 1.6
Values 3.9 6.7 3.3 5.7
[22]
ref_hepatocyte ANAPC16
Mean 18.3
Standard deviation 8.8
Values 23 15 4.6 22 27
[23]
HepG2 ANAPC16
Mean 45.9
Standard deviation 1.7
Values 47 45
[24]
HepG2.C3A ANAPC16
Mean 66.9
Standard deviation 9.3
Values 60 74
[25]
HuH.7 ANAPC16
Mean 28.7
Standard deviation 4.9
Values 27 25 34
[26]
SNU475 ANAPC16
Mean 25
Standard deviation 5
Values 29 21
[27]
THLE ANAPC16
Mean 32.9
Standard deviation 0.68
Values 32 33
[28]
liver ANAPC16
Mean 37.9
Standard deviation 22
Values 61 20 52 18
[29]
ref_hepatocyte ANAPC5
Mean 17.3
Standard deviation 3.4
Values 12 20 18 20 17
[30]
HepG2 ANAPC5
Mean 70
Standard deviation 5.4
Values 66 74
[31]
HepG2.C3A ANAPC5
Mean 99.1
Standard deviation 8.6
Values 93 1.1e+02
[32]
HuH.7 ANAPC5
Mean 106
Standard deviation 32
Values 1.2e+02 70 1.3e+02
[33]
SNU475 ANAPC5
Mean 40.1
Standard deviation 6.5
Values 45 36
[34]
THLE ANAPC5
Mean 61.8
Standard deviation 4.4
Values 59 65
[35]
liver ANAPC5
Mean 40.2
Standard deviation 5.8
Values 42 37 47 34
[36]
ref_hepatocyte CDC27
Mean 13.6
Standard deviation 15
Values 38 16 8.3 2.9 3.1
[37]
HepG2 CDC27
Mean 35
Standard deviation 19
Values 22 48
[38]
HepG2.C3A CDC27
Mean 55.7
Standard deviation 20
Values 42 70
[39]
HuH.7 CDC27
Mean 34.1
Standard deviation 3.9
Values 39 32 31
[40]
SNU475 CDC27
Mean 56.9
Standard deviation 0.87
Values 56 58
[41]
THLE CDC27
Mean 46.4
Standard deviation 3.2
Values 44 49
[42]
liver CDC27
Mean 21.5
Standard deviation 3.1
Values 20 26 20 21
[43]
ref_hepatocyte CDC16
Mean 12.3
Standard deviation 3.1
Values 8.9 13 15 15 9.1
[44]
HepG2 CDC16
Mean 19.3
Standard deviation 0.027
Values 19 19
[45]
HepG2.C3A CDC16
Mean 20.2
Standard deviation 2.9
Values 22 18
[46]
HuH.7 CDC16
Mean 12.3
Standard deviation 2
Values 11 12 15
[47]
SNU475 CDC16
Mean 16.9
Standard deviation 3.3
Values 19 15
[48]
THLE CDC16
Mean 25.8
Standard deviation 4.3
Values 23 29
[49]
liver CDC16
Mean 16
Standard deviation 5.4
Values 17 16 22 9
[50]
ref_hepatocyte UBE2C
Mean 11
Standard deviation 13
Values 28 21 2.1 1.8 1.8
[51]
HepG2 UBE2C
Mean 20.7
Standard deviation 2
Values 22 19
[52]
HepG2.C3A UBE2C
Mean 24
Standard deviation 9.1
Values 18 30
[53]
HuH.7 UBE2C
Mean 39
Standard deviation 20
Values 45 17 55
[54]
SNU475 UBE2C
Mean 22.1
Standard deviation 5.8
Values 18 26
[55]
THLE UBE2C
Mean 46
Standard deviation 12
Values 38 54
[56]
liver UBE2C
Mean 1.12
Standard deviation 1.5
Values 0.89 0.3 3.3 0.013
[57]
ref_hepatocyte UBE2S
Mean 9.88
Standard deviation 5.6
Values 4.4 13 17 11 4.4
[58]
HepG2 UBE2S
Mean 29.7
Standard deviation 11
Values 38 22
[59]
HepG2.C3A UBE2S
Mean 19.7
Standard deviation 0.91
Values 19 20
[60]
HuH.7 UBE2S
Mean 86.1
Standard deviation 32
Values 86 54 1.2e+02
[61]
SNU475 UBE2S
Mean 35.4
Standard deviation 5.6
Values 31 39
[62]
THLE UBE2S
Mean 102
Standard deviation 13
Values 92 1.1e+02
[63]
liver UBE2S
Mean 2.33
Standard deviation 0.97
Values 3.1 1.7 3.2 1.3
[64]
ref_hepatocyte CCNB1
Mean 8.2
Standard deviation 8.6
Values 15 20 1.8 3.1 1.3
[65]
HepG2 CCNB1
Mean 65.1
Standard deviation 21
Values 50 80
[66]
HepG2.C3A CCNB1
Mean 68.3
Standard deviation 39
Values 41 96
[67]
HuH.7 CCNB1
Mean 74.2
Standard deviation 37
Values 87 33 1e+02
[68]
SNU475 CCNB1
Mean 45.8
Standard deviation 3.3
Values 48 44
[69]
THLE CCNB1
Mean 101
Standard deviation 30
Values 80 1.2e+02
[70]
liver CCNB1
Mean 2.29
Standard deviation 1.6
Values 2.3 2.4 4.2 0.28
[71]
ref_hepatocyte CDC23
Mean 7.24
Standard deviation 2.5
Values 8.6 11 6.9 4.9 4.9
[72]
HepG2 CDC23
Mean 20.7
Standard deviation 3.9
Values 18 24
[73]
HepG2.C3A CDC23
Mean 21.2
Standard deviation 4.4
Values 18 24
[74]
HuH.7 CDC23
Mean 24.3
Standard deviation 6
Values 26 18 29
[75]
SNU475 CDC23
Mean 27.2
Standard deviation 0.72
Values 27 28
[76]
THLE CDC23
Mean 24.9
Standard deviation 1.5
Values 24 26
[77]
liver CDC23
Mean 11.8
Standard deviation 3.1
Values 13 11 15 8
[78]
ref_hepatocyte CDK1
Mean 5.78
Standard deviation 6.9
Values 13 14 0.06 1.6 0.72
[79]
HepG2 CDK1
Mean 30.4
Standard deviation 14
Values 21 40
[80]
HepG2.C3A CDK1
Mean 113
Standard deviation 85
Values 53 1.7e+02
[81]
HuH.7 CDK1
Mean 45.1
Standard deviation 21
Values 55 21 60
[82]
SNU475 CDK1
Mean 51.1
Standard deviation 5
Values 48 55
[83]
THLE CDK1
Mean 101
Standard deviation 11
Values 93 1.1e+02
[84]
liver CDK1
Mean 1.48
Standard deviation 1.4
Values 1 1.4 3.4 0.013
[85]
ref_hepatocyte ANAPC7
Mean 5.77
Standard deviation 1.7
Values 4.5 7.7 7.4 5.2 4
[86]
HepG2 ANAPC7
Mean 25.5
Standard deviation 4
Values 23 28
[87]
HepG2.C3A ANAPC7
Mean 30
Standard deviation 1.6
Values 29 31
[88]
HuH.7 ANAPC7
Mean 20
Standard deviation 6.2
Values 23 13 24
[89]
SNU475 ANAPC7
Mean 19.8
Standard deviation 0.8
Values 19 20
[90]
THLE ANAPC7
Mean 26.5
Standard deviation 2.3
Values 25 28
[91]
liver ANAPC7
Mean 9.34
Standard deviation 1.7
Values 9 10 11 7.1
[92]
ref_hepatocyte ANAPC2
Mean 5.57
Standard deviation 3.1
Values 1.7 3.8 5.3 7.8 9.3
[93]
HepG2 ANAPC2
Mean 18.7
Standard deviation 2.4
Values 17 20
[94]
HepG2.C3A ANAPC2
Mean 11.3
Standard deviation 0.75
Values 11 12
[95]
HuH.7 ANAPC2
Mean 16.6
Standard deviation 4.5
Values 18 12 20
[96]
SNU475 ANAPC2
Mean 10.5
Standard deviation 0.9
Values 11 9.9
[97]
THLE ANAPC2
Mean 11.5
Standard deviation 2.7
Values 9.6 13
[98]
liver ANAPC2
Mean 8.17
Standard deviation 1.9
Values 7.8 8.5 5.9 10
[99]
ref_hepatocyte PLK1
Mean 4.92
Standard deviation 5.9
Values 13 9.1 0.65 1.1 0.48
[100]
HepG2 PLK1
Mean 61.1
Standard deviation 5.4
Values 57 65
[101]
HepG2.C3A PLK1
Mean 45.5
Standard deviation 17
Values 33 58
[102]
HuH.7 PLK1
Mean 39.6
Standard deviation 20
Values 55 17 47
[103]
SNU475 PLK1
Mean 21.4
Standard deviation 1.4
Values 20 22
[104]
THLE PLK1
Mean 49.2
Standard deviation 23
Values 33 65
[105]
liver PLK1
Mean 1.13
Standard deviation 1.1
Values 1.2 0.53 2.7 0.093
[106]
ref_hepatocyte ANAPC1
Mean 3.66
Standard deviation 1.4
Values 5.4 4.5 3.9 2.3 2.2
[107]
HepG2 ANAPC1
Mean 42.9
Standard deviation 9.5
Values 36 50
[108]
HepG2.C3A ANAPC1
Mean 43.4
Standard deviation 8.5
Values 37 49
[109]
HuH.7 ANAPC1
Mean 38.4
Standard deviation 12
Values 51 27 38
[110]
SNU475 ANAPC1
Mean 25.5
Standard deviation 0.94
Values 26 25
[111]
THLE ANAPC1
Mean 28.9
Standard deviation 5.8
Values 25 33
[112]
liver ANAPC1
Mean 14.2
Standard deviation 7.2
Values 7.4 22 8.8 19
[113]
ref_hepatocyte ANAPC4
Mean 2.72
Standard deviation 1
Values 2.7 4.2 3 2 1.7
[114]
HepG2 ANAPC4
Mean 6.87
Standard deviation 3
Values 4.8 9
[115]
HepG2.C3A ANAPC4
Mean 11.6
Standard deviation 1.5
Values 11 13
[116]
HuH.7 ANAPC4
Mean 14
Standard deviation 1.6
Values 14 12 16
[117]
SNU475 ANAPC4
Mean 11.4
Standard deviation 1.7
Values 13 10
[118]
THLE ANAPC4
Mean 8.86
Standard deviation 1.3
Values 7.9 9.8
[119]
liver ANAPC4
Mean 7.61
Standard deviation 3
Values 11 5.6 9 4.7
[120]
ref_hepatocyte UBE2D1
Mean 2.43
Standard deviation 1.1
Values 2.2 1.2 4.1 1.7 2.8
[121]
HepG2 UBE2D1
Mean 9.29
Standard deviation 2.7
Values 7.4 11
[122]
HepG2.C3A UBE2D1
Mean 15.1
Standard deviation 2.9
Values 13 17
[123]
HuH.7 UBE2D1
Mean 18.4
Standard deviation 3.8
Values 21 14 20
[124]
SNU475 UBE2D1
Mean 12.8
Standard deviation 0.14
Values 13 13
[125]
THLE UBE2D1
Mean 12.2
Standard deviation 0.065
Values 12 12
[126]
liver UBE2D1
Mean 4.88
Standard deviation 2.6
Values 6.8 2.9 7.4 2.4
[127]
ref_hepatocyte ANAPC10
Mean 2.16
Standard deviation 0.77
Values 1.8 2 1.3 2.2 3.4
[128]
HepG2 ANAPC10
Mean 4.04
Standard deviation 0.5
Values 3.7 4.4
[129]
HepG2.C3A ANAPC10
Mean 6.67
Standard deviation 1.5
Values 5.6 7.7
[130]
HuH.7 ANAPC10
Mean 4.18
Standard deviation 0.77
Values 3.7 3.8 5.1
[131]
SNU475 ANAPC10
Mean 3.39
Standard deviation 0.1
Values 3.5 3.3
[132]
THLE ANAPC10
Mean 6.54
Standard deviation 0.14
Values 6.4 6.6
[133]
liver ANAPC10
Mean 3.33
Standard deviation 2.2
Values 5.8 1.8 4.5 1.1
[134]
ref_hepatocyte ANAPC15
Missing
[135]
HepG2 ANAPC15
Mean 3.23
Standard deviation 0.75
Values 2.7 3.8
[136]
HepG2.C3A ANAPC15
Mean 2.36
Standard deviation 0.71
Values 1.9 2.9
[137]
HuH.7 ANAPC15
Mean 2.08
Standard deviation 0.91
Values 2.1 1.2 3
[138]
SNU475 ANAPC15
Mean 3.3
Standard deviation 1.3
Values 4.2 2.4
[139]
THLE ANAPC15
Mean 2.63
Standard deviation 1.1
Values 1.9 3.4
[140]
liver ANAPC15
Mean 1.17
Standard deviation 0.99
Values 2.1 0.37 1.9 0.25