REACTOME_PHASE_0_RAPID_DEPOLARISATION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CALM1 | Calmodulin-1 | [1] | -0.08[2] | -1.49[3] | -0.45[4] | 0.26[5] | 0.06[6] | 0.10[7] |
2 | RANGRF | Ran guanine nucleotide release factor | [8] | -2.11[9] | -2.80[10] | -3.46[11] | -3.84[12] | -3.21[13] | -4.19[14] |
3 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | [15] | -0.02[16] | -1.17[17] | 0.94[18] | -0.65[19] | -0.93[20] | -0.11[21] |
4 | CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma | 0.62[22] | 0.38[23] | 0.58[24] | 0.36[25] | 0.45[26] | -0.56[27] | |
5 | FGF13 | Fibroblast growth factor 13 | [28] | -3.77[29] | -6.53[30] | [31] | -9.63[32] | -8.99[33] | -2.77[34] |
6 | SCN9A | Sodium channel protein type 9 subunit alpha | [35] | 0.99[36] | 3.43[37] | 2.97[38] | 0.72[39] | -1.83[40] | 2.08[41] |
7 | CAMK2B | Calcium/calmodulin-dependent protein kinase type II subunit beta | [42] | -2.69[43] | -5.46[44] | -7.84[45] | -4.18[46] | -3.02[47] | -0.37[48] |
8 | SCN1B | Sodium channel subunit beta-1 | [49] | 1.18[50] | -0.82[51] | -2.61[52] | -0.77[53] | 2.03[54] | -1.06[55] |
9 | FGF11 | Fibroblast growth factor 11 | [56] | 3.80[57] | 2.17[58] | 3.72[59] | 1.20[60] | 0.26[61] | -2.05[62] |
10 | FGF14 | Fibroblast growth factor 14 | [63] | [64] | [65] | [66] | -4.63[67] | -2.40[68] | 0.43[69] |
11 | SCN8A | Sodium channel protein type 8 subunit alpha | [70] | 1.16[71] | -4.24[72] | 2.79[73] | 3.63[74] | 2.74[75] | 3.59[76] |
12 | CACNG8 | Voltage-dependent calcium channel gamma-8 subunit | [77] | 0.87[78] | 0.54[79] | -0.21[80] | 0.12[81] | 3.65[82] | -1.96[83] |
13 | CACNG7 | Voltage-dependent calcium channel gamma-7 subunit | [84] | -7.03[85] | -6.56[86] | [87] | -3.96[88] | 2.44[89] | [90] |
14 | CACNB2 | Voltage-dependent L-type calcium channel subunit beta-2 | [91] | -0.15[92] | 0.36[93] | 0.96[94] | 2.25[95] | 1.19[96] | 3.52[97] |
15 | CACNB1 | Voltage-dependent L-type calcium channel subunit beta-1 | [98] | 2.89[99] | -0.03[100] | 2.14[101] | 1.41[102] | 3.23[103] | -0.62[104] |
16 | SCN11A | Sodium channel protein type 11 subunit alpha | [105] | -0.27[106] | -0.05[107] | -0.72[108] | -0.47[109] | -0.71[110] | 0.28[111] |
17 | SCN2A | Sodium channel protein type 2 subunit alpha | [112] | -0.53[113] | 0.66[114] | 1.47[115] | 0.97[116] | 3.70[117] | 0.49[118] |
18 | SCN1A | Sodium channel protein type 1 subunit alpha | [119] | 2.66[120] | 8.83[121] | -2.00[122] | 0.24[123] | -0.49[124] | -0.92[125] |
19 | SCN2B | Sodium channel subunit beta-2 | [126] | 1.77[127] | 0.12[128] | -1.27[129] | -3.40[130] | -0.13[131] | -0.23[132] |
20 | CACNG4 | Voltage-dependent calcium channel gamma-4 subunit | [133] | 4.65[134] | 4.57[135] | -3.13[136] | 2.41[137] | -3.84[138] | -2.74[139] |
21 | FGF12 | Fibroblast growth factor 12 | [140] | [141] | [142] | 1.67[143] | -3.02[144] | 2.67[145] | 1.08[146] |
22 | CACNA2D | Voltage-dependent calcium channel subunit alpha-2/delta-2 | [147] | -1.46[148] | -0.72[149] | 0.45[150] | -1.08[151] | 1.20[152] | 0.31[153] |
23 | SCN3B | Sodium channel subunit beta-3 | [154] | 0.24[155] | -1.14[156] | -2.88[157] | 0.04[158] | 0.08[159] | 0.16[160] |
24 | SCN4B | Sodium channel subunit beta-4 | [161] | 1.74[162] | 0.12[163] | 0.63[164] | -1.24[165] | 1.79[166] | 1.08[167] |
25 | SCN4A | Sodium channel protein type 4 subunit alpha | [168] | 3.07[169] | -0.77[170] | 0.57[171] | -2.10[172] | -1.07[173] | 2.31[174] |
26 | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha-1C | [175] | 4.57[176] | 0.62[177] | 4.06[178] | 4.40[179] | 7.15[180] | 6.79[181] |
27 | SCN5A | Sodium channel protein type 5 subunit alpha | [182] | 8.58[183] | 0.63[184] | 0.86[185] | 2.80[186] | 6.66[187] | 1.06[188] |
28 | SCN7A | Sodium channel protein type 7 subunit alpha | [189] | [190] | [191] | [192] | [193] | [194] | [195] |
29 | CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha | [196] | [197] | [198] | [199] | [200] | [201] | [202] |
30 | CACNG6 | Voltage-dependent calcium channel gamma-6 subunit | [203] | [204] | [205] | [206] | [207] | [208] | [209] |
31 | SCN3A | Sodium channel protein type 3 subunit alpha | [210] | [211] | [212] | [213] | [214] | [215] | [216] |
32 | SCN10A | Sodium channel protein type 10 subunit alpha | [217] | [218] | [219] | [220] | [221] | [222] | [223] |