REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.34[2] -0.25[3] -0.41[4] -0.73[5] -0.44[6] 0.02[7]
2 SQSTM1 Sequestosome-1 [8] 0.11[9] -0.66[10] -0.42[11] 0.88[12] 0.62[13] 0.10[14]
3 RPS27A Ubiquitin-40S ribosomal protein S27a [15] [16] [17] [18] [19] [20] [21]
4 UBC Polyubiquitin-C [22] 0.10[23] 0.50[24] -0.04[25] 0.12[26] -0.06[27] 0.47[28]
5 UBA52 Ubiquitin-60S ribosomal protein L40 [29] 2.54[30] 2.74[31] 3.47[32] 1.52[33] 2.16[34] 1.24[35]
6 IRAK1 Interleukin-1 receptor-associated kinase 1 [36] 3.28[37] 2.96[38] 1.63[39] 2.84[40] 3.04[41] 1.21[42]
7 MYD88 Myeloid differentiation primary response protein MyD88 [43] 1.67[44] 2.02[45] 1.15[46] 1.01[47] 1.14[48] 2.69[49]
8 RIPK2 Receptor-interacting serine/threonine-protein kinase 2 [50] 1.29[51] 2.17[52] 1.88[53] 1.85[54] 1.65[55] 0.76[56]
9 PRKCI Protein kinase C iota type [57] 2.92[58] 3.89[59] 5.18[60] 3.20[61] 3.44[62] 2.15[63]
10 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta [64] 2.38[65] 2.73[66] 2.53[67] 2.31[68] 2.23[69] 3.08[70]
11 TRAF6 TNF receptor-associated factor 6 [71] 2.95[72] 3.13[73] 3.39[74] 3.71[75] 3.00[76] 4.80[77]
12 NGFR Tumor necrosis factor receptor superfamily member 16 [78] 10.33[79] 3.77[80] -0.54[81] 3.80[82] 4.57[83] 9.50[84]
13 NGF Beta-nerve growth factor [85] [86] [87] [88] [89] [90] [91]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte SQSTM1
Mean 520
Standard deviation 6e+02
Values 2e+02 1.6e+03 4.7e+02 1.7e+02 1.9e+02
[9]
HepG2 SQSTM1
Mean 340
Standard deviation 1.6e+02
Values 4.5e+02 2.3e+02
[10]
HepG2.C3A SQSTM1
Mean 146
Standard deviation 39
Values 1.7e+02 1.2e+02
[11]
HuH.7 SQSTM1
Mean 205
Standard deviation 98
Values 1.5e+02 3.2e+02 1.5e+02
[12]
SNU475 SQSTM1
Mean 424
Standard deviation 77
Values 3.7e+02 4.8e+02
[13]
THLE SQSTM1
Mean 447
Standard deviation 1.3e+02
Values 3.6e+02 5.4e+02
[14]
liver SQSTM1
Mean 213
Standard deviation 1.3e+02
Values 2.6e+02 1.4e+02 3.7e+02 80
[15]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[16]
HepG2 RPS27A
Missing
[17]
HepG2.C3A RPS27A
Missing
[18]
HuH.7 RPS27A
Missing
[19]
SNU475 RPS27A
Missing
[20]
THLE RPS27A
Missing
[21]
liver RPS27A
Missing
[22]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[23]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[24]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[25]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[26]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[27]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[28]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[29]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[30]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[31]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[32]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[33]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[34]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[35]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[36]
ref_hepatocyte IRAK1
Mean 21.3
Standard deviation 13
Values 18 30 38 16 5
[37]
HepG2 IRAK1
Mean 126
Standard deviation 40
Values 1.5e+02 97
[38]
HepG2.C3A IRAK1
Mean 73.4
Standard deviation 2.1
Values 72 75
[39]
HuH.7 IRAK1
Mean 34.7
Standard deviation 4.6
Values 40 31 34
[40]
SNU475 IRAK1
Mean 67.9
Standard deviation 14
Values 58 78
[41]
THLE IRAK1
Mean 98.2
Standard deviation 12
Values 90 1.1e+02
[42]
liver IRAK1
Mean 18.8
Standard deviation 3.7
Values 17 19 15 24
[43]
ref_hepatocyte MYD88
Mean 12.3
Standard deviation 6.2
Values 5.4 6 14 19 17
[44]
HepG2 MYD88
Mean 23.8
Standard deviation 12
Values 16 32
[45]
HepG2.C3A MYD88
Mean 22.1
Standard deviation 5.1
Values 18 26
[46]
HuH.7 MYD88
Mean 14.3
Standard deviation 1.1
Values 15 13 15
[47]
SNU475 MYD88
Mean 11
Standard deviation 1.1
Values 12 10
[48]
THLE MYD88
Mean 15.1
Standard deviation 1.7
Values 14 16
[49]
liver MYD88
Mean 30.3
Standard deviation 21
Values 47 9.8 51 14
[50]
ref_hepatocyte RIPK2
Mean 4.75
Standard deviation 3.4
Values 4.6 4.7 10 2.7 1.5
[51]
HepG2 RIPK2
Mean 7.05
Standard deviation 1.9
Values 5.7 8.4
[52]
HepG2.C3A RIPK2
Mean 9.51
Standard deviation 0.29
Values 9.3 9.7
[53]
HuH.7 RIPK2
Mean 9.2
Standard deviation 1.4
Values 9.4 10 7.7
[54]
SNU475 RIPK2
Mean 7.59
Standard deviation 1.2
Values 6.7 8.5
[55]
THLE RIPK2
Mean 8.33
Standard deviation 0.54
Values 7.9 8.7
[56]
liver RIPK2
Mean 3.08
Standard deviation 0.94
Values 3.6 2.6 4.1 2
[57]
ref_hepatocyte PRKCI
Mean 4.42
Standard deviation 3.3
Values 7.2 8.6 3.6 1 1.8
[58]
HepG2 PRKCI
Mean 20.3
Standard deviation 5.5
Values 16 24
[59]
HepG2.C3A PRKCI
Mean 29
Standard deviation 6.2
Values 25 33
[60]
HuH.7 PRKCI
Mean 84.5
Standard deviation 10
Values 92 89 73
[61]
SNU475 PRKCI
Mean 18.1
Standard deviation 2.4
Values 20 16
[62]
THLE PRKCI
Mean 26.9
Standard deviation 1.3
Values 26 28
[63]
liver PRKCI
Mean 7.49
Standard deviation 1.8
Values 6.9 10 7.1 5.9
[64]
ref_hepatocyte IKBKB
Mean 3.48
Standard deviation 0.8
Values 2.9 4.3 4.2 3.5 2.5
[65]
HepG2 IKBKB
Mean 11
Standard deviation 0.46
Values 11 11
[66]
HepG2.C3A IKBKB
Mean 10.2
Standard deviation 1
Values 11 9.5
[67]
HuH.7 IKBKB
Mean 10.6
Standard deviation 1.9
Values 11 8.4 12
[68]
SNU475 IKBKB
Mean 7.65
Standard deviation 1.8
Values 8.9 6.4
[69]
THLE IKBKB
Mean 9.14
Standard deviation 0.21
Values 9.3 9
[70]
liver IKBKB
Mean 11.2
Standard deviation 0.34
Values 11 11 11 12
[71]
ref_hepatocyte TRAF6
Mean 0.965
Standard deviation 0.32
Values 0.82 1 1.5 0.7 0.8
[72]
HepG2 TRAF6
Mean 4.54
Standard deviation 0.72
Values 4 5
[73]
HepG2.C3A TRAF6
Mean 3.74
Standard deviation 0.086
Values 3.8 3.7
[74]
HuH.7 TRAF6
Mean 5.32
Standard deviation 1
Values 5 6.4 4.5
[75]
SNU475 TRAF6
Mean 5.61
Standard deviation 0.46
Values 5.9 5.3
[76]
THLE TRAF6
Mean 4.31
Standard deviation 0.54
Values 3.9 4.7
[77]
liver TRAF6
Mean 10.3
Standard deviation 0.99
Values 9.7 12 9.8 10
[78]
ref_hepatocyte NGFR
Mean 0.0296
Standard deviation 0.032
Values 0 0 0.03 0.078 0.041
[79]
HepG2 NGFR
Mean 23.1
Standard deviation 11
Values 15 31
[80]
HepG2.C3A NGFR
Mean 0.179
Standard deviation 0.0052
Values 0.17 0.18
[81]
HuH.7 NGFR
Mean 0.0107
Standard deviation 0.0051
Values 0.016 0.0064 0.0094
[82]
SNU475 NGFR
Mean 0.183
Standard deviation 0.21
Values 0.037 0.33
[83]
THLE NGFR
Mean 0.394
Standard deviation 0.045
Values 0.43 0.36
[84]
liver NGFR
Mean 8.18
Standard deviation 5.6
Values 16 3.2 5.7 7.7
[85]
ref_hepatocyte NGF
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 NGF
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A NGF
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 NGF
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 NGF
Mean 1.32
Standard deviation 0.58
Values 0.91 1.7
[90]
THLE NGF
Mean 0.258
Standard deviation 0.011
Values 0.27 0.25
[91]
liver NGF
Mean 0.426
Standard deviation 0.42
Values 1 0.071 0.46 0.16