REACTOME_P38MAPK_EVENTS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RALB Ras-related protein Ral-B [1] -1.73[2] -1.83[3] -2.35[4] -1.73[5] -1.77[6] -1.35[7]
2 RALA Ras-related protein Ral-A [8] -1.70[9] -1.02[10] -0.53[11] -0.97[12] -0.40[13] -1.10[14]
3 NRAS GTPase NRas [15] 0.12[16] 0.49[17] 1.21[18] 0.60[19] 0.46[20] 0.39[21]
4 MAPKAPK2 MAP kinase-activated protein kinase 2 [22] -0.05[23] -1.08[24] -0.35[25] 1.00[26] 0.49[27] -0.31[28]
5 HRAS GTPase HRas [29] -1.51[30] -2.29[31] -2.77[32] -1.34[33] -1.28[34] -2.03[35]
6 KRAS GTPase KRas [36] -1.02[37] -1.11[38] 0.80[39] 0.41[40] 0.35[41] 1.31[42]
7 MAPK14 Mitogen-activated protein kinase 14 [43] 0.97[44] 0.97[45] 0.86[46] 1.29[47] 1.04[48] 1.92[49]
8 MAPKAPK3 MAP kinase-activated protein kinase 3 [50] 0.51[51] 0.38[52] -0.21[53] -1.87[54] 0.12[55] 0.40[56]
9 MAPK13 Mitogen-activated protein kinase 13 [57] 1.84[58] 2.17[59] -0.20[60] -2.28[61] -0.48[62] -1.08[63]
10 SRC Proto-oncogene tyrosine-protein kinase Src [64] 2.52[65] 2.43[66] 1.75[67] 2.01[68] 1.46[69] -0.21[70]
11 RALGDS Ral guanine nucleotide dissociation stimulator [71] 2.54[72] 2.12[73] 1.23[74] 2.39[75] 2.24[76] 1.91[77]
12 MAPK12 Mitogen-activated protein kinase 12 [78] 2.32[79] 1.91[80] 3.33[81] 1.09[82] 2.62[83] -0.27[84]
13 MAPK11 Mitogen-activated protein kinase 11 [85] -0.68[86] -0.85[87] -1.42[88] -0.04[89] 2.24[90] 0.80[91]
[1]
ref_hepatocyte RALB
Mean 35
Standard deviation 33
Values 76 66 17 10 6.2
[2]
HepG2 RALB
Mean 33
Standard deviation 2.3
Values 31 35
[3]
HepG2.C3A RALB
Mean 28.9
Standard deviation 1.5
Values 28 30
[4]
HuH.7 RALB
Mean 15.6
Standard deviation 3.6
Values 18 11 18
[5]
SNU475 RALB
Mean 25.5
Standard deviation 1.8
Values 27 24
[6]
THLE RALB
Mean 22.8
Standard deviation 4.3
Values 20 26
[7]
liver RALB
Mean 12.6
Standard deviation 5.4
Values 11 11 20 7.5
[8]
ref_hepatocyte RALA
Mean 21.2
Standard deviation 18
Values 26 49 21 5.5 5.1
[9]
HepG2 RALA
Mean 20.5
Standard deviation 1.4
Values 19 21
[10]
HepG2.C3A RALA
Mean 30.5
Standard deviation 1.2
Values 31 30
[11]
HuH.7 RALA
Mean 33.1
Standard deviation 1.5
Values 35 32 33
[12]
SNU475 RALA
Mean 26.1
Standard deviation 0.25
Values 26 26
[13]
THLE RALA
Mean 35.8
Standard deviation 8.4
Values 30 42
[14]
liver RALA
Mean 9.04
Standard deviation 6.3
Values 15 3.6 14 3.5
[15]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[16]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[17]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[18]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[19]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[20]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[21]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[22]
ref_hepatocyte MAPKAPK2
Mean 13.1
Standard deviation 7.6
Values 5.2 10 24 17 8.7
[23]
HepG2 MAPKAPK2
Mean 39.7
Standard deviation 1.4
Values 41 39
[24]
HepG2.C3A MAPKAPK2
Mean 18.1
Standard deviation 4.5
Values 21 15
[25]
HuH.7 MAPKAPK2
Mean 23.2
Standard deviation 2.9
Values 25 20 25
[26]
SNU475 MAPKAPK2
Mean 63.2
Standard deviation 4
Values 66 60
[27]
THLE MAPKAPK2
Mean 40.9
Standard deviation 0.33
Values 41 41
[28]
liver MAPKAPK2
Mean 9.67
Standard deviation 2.5
Values 10 11 6 11
[29]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[30]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[31]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[32]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[33]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[34]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[35]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[36]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[37]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[38]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[39]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[40]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[41]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[42]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[43]
ref_hepatocyte MAPK14
Mean 8.71
Standard deviation 2
Values 12 8.5 7.2 7.5 8.3
[44]
HepG2 MAPK14
Mean 53.4
Standard deviation 8.7
Values 47 60
[45]
HepG2.C3A MAPK14
Mean 49.9
Standard deviation 0.11
Values 50 50
[46]
HuH.7 MAPK14
Mean 35.7
Standard deviation 1.3
Values 37 36 34
[47]
SNU475 MAPK14
Mean 51.3
Standard deviation 0.4
Values 52 51
[48]
THLE MAPK14
Mean 40
Standard deviation 3.6
Values 37 43
[49]
liver MAPK14
Mean 30.1
Standard deviation 8.3
Values 24 38 22 37
[50]
ref_hepatocyte MAPKAPK3
Mean 8.03
Standard deviation 3.9
Values 5.9 12 13 4.9 4.9
[51]
HepG2 MAPKAPK3
Mean 35.8
Standard deviation 0.92
Values 36 35
[52]
HepG2.C3A MAPKAPK3
Mean 30.6
Standard deviation 0.36
Values 30 31
[53]
HuH.7 MAPKAPK3
Mean 15.7
Standard deviation 2.2
Values 17 13 16
[54]
SNU475 MAPKAPK3
Mean 5.29
Standard deviation 0.058
Values 5.2 5.3
[55]
THLE MAPKAPK3
Mean 19.5
Standard deviation 4.7
Values 16 23
[56]
liver MAPKAPK3
Mean 9.68
Standard deviation 1.8
Values 12 7.4 10 9.3
[57]
ref_hepatocyte MAPK13
Mean 5.46
Standard deviation 4.5
Values 11 4 9.1 2.7 0.39
[58]
HepG2 MAPK13
Mean 61.1
Standard deviation 22
Values 77 46
[59]
HepG2.C3A MAPK13
Mean 72
Standard deviation 5.6
Values 76 68
[60]
HuH.7 MAPK13
Mean 10.8
Standard deviation 1.6
Values 11 12 9.2
[61]
SNU475 MAPK13
Mean 2.71
Standard deviation 2.1
Values 1.2 4.2
[62]
THLE MAPK13
Mean 8.71
Standard deviation 2.1
Values 7.2 10
[63]
liver MAPK13
Mean 2.36
Standard deviation 1.5
Values 4.6 1.5 1.5 1.8
[64]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[65]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[66]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[67]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[68]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[69]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[70]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[71]
ref_hepatocyte RALGDS
Mean 0.924
Standard deviation 0.46
Values 1.4 0.32 0.71 1.4 0.81
[72]
HepG2 RALGDS
Mean 16.9
Standard deviation 1.1
Values 18 16
[73]
HepG2.C3A RALGDS
Mean 11.8
Standard deviation 2.6
Values 14 9.9
[74]
HuH.7 RALGDS
Mean 4.9
Standard deviation 0.56
Values 4.4 5.5 4.8
[75]
SNU475 RALGDS
Mean 11.7
Standard deviation 5.2
Values 15 8
[76]
THLE RALGDS
Mean 9.68
Standard deviation 0.73
Values 9.2 10
[77]
liver RALGDS
Mean 3.17
Standard deviation 1.7
Values 1.7 3.6 2.1 5.3
[78]
ref_hepatocyte MAPK12
Mean 0.743
Standard deviation 0.94
Values 2.4 0.4 0.21 0.41 0.28
[79]
HepG2 MAPK12
Mean 11.6
Standard deviation 3.6
Values 14 9
[80]
HepG2.C3A MAPK12
Mean 8.16
Standard deviation 0.15
Values 8.1 8.3
[81]
HuH.7 MAPK12
Mean 16.9
Standard deviation 6.7
Values 18 9.7 23
[82]
SNU475 MAPK12
Mean 3.82
Standard deviation 1.9
Values 5.2 2.5
[83]
THLE MAPK12
Mean 10.2
Standard deviation 1.3
Values 9.2 11
[84]
liver MAPK12
Mean 0.564
Standard deviation 0.13
Values 0.47 0.43 0.67 0.69
[85]
ref_hepatocyte MAPK11
Mean 0.382
Standard deviation 0.29
Values 0 0.34 0.22 0.71 0.64
[86]
HepG2 MAPK11
Mean 0.749
Standard deviation 0.18
Values 0.62 0.88
[87]
HepG2.C3A MAPK11
Mean 0.621
Standard deviation 0.12
Values 0.53 0.71
[88]
HuH.7 MAPK11
Mean 0.322
Standard deviation 0.15
Values 0.28 0.2 0.49
[89]
SNU475 MAPK11
Mean 0.898
Standard deviation 0.33
Values 1.1 0.66
[90]
THLE MAPK11
Mean 4.01
Standard deviation 0.7
Values 4.5 3.5
[91]
liver MAPK11
Mean 0.609
Standard deviation 0.32
Values 0.96 0.49 0.23 0.75