REACTOME_OTHER_INTERLEUKIN_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 IL32 Interleukin-32 [1] -1.30[2] -1.67[3] -4.81[4] -4.40[5] -5.84[6] -3.04[7]
2 SDC1 Syndecan-1 [8] 1.10[9] 0.92[10] 1.69[11] 0.11[12] -2.55[13] 2.04[14]
3 JAK1 Tyrosine-protein kinase JAK1 [15] 2.10[16] 1.88[17] 2.47[18] 3.09[19] 3.38[20] 2.79[21]
4 CD4 T-cell surface glycoprotein CD4 [22] -4.16[23] -1.70[24] -3.91[25] -4.99[26] -7.39[27] 1.17[28]
5 STX4 Syntaxin-4 [29] 0.41[30] 0.81[31] 1.26[32] 0.64[33] 0.55[34] -0.88[35]
6 CASP3 Caspase-3 [36] 1.73[37] 2.69[38] 0.56[39] 1.57[40] 2.21[41] 0.45[42]
7 STXBP2 Syntaxin-binding protein 2 [43] 1.84[44] 1.95[45] 2.29[46] 1.24[47] 2.13[48] 0.68[49]
8 TXLNA Alpha-taxilin [50] 3.13[51] 3.23[52] 3.99[53] 3.54[54] 3.48[55] 3.20[56]
9 IL10RB Interleukin-10 receptor subunit beta [57] 1.05[58] 1.15[59] 0.55[60] 2.25[61] 2.02[62] 1.28[63]
10 VAMP2 Vesicle-associated membrane protein 2 [64] 0.24[65] 0.89[66] 1.66[67] 2.00[68] 1.45[69] 1.06[70]
11 CSF1 Macrophage colony-stimulating factor 1 [71] 2.63[72] -1.79[73] 2.81[74] 5.46[75] 4.58[76] 1.67[77]
12 TYK2 Non-receptor tyrosine-protein kinase TYK2 [78] 2.73[79] 3.37[80] 3.92[81] 3.21[82] 3.78[83] 3.24[84]
13 STX3 Syntaxin-3 [85] 4.23[86] 4.22[87] 3.88[88] 3.71[89] 3.55[90] 1.70[91]
14 CSF3 Granulocyte colony-stimulating factor [92] -0.58[93] -3.90[94] -3.90[95] -4.48[96] 6.57[97] -6.16[98]
15 CSF1R Macrophage colony-stimulating factor 1 receptor [99] -4.71[100] -7.35[101] -5.59[102] 2.22[103] -2.75[104] 3.95[105]
16 STX1A Syntaxin-1A [106] 2.53[107] 2.78[108] 1.71[109] 5.06[110] 3.71[111] 0.09[112]
17 CSF3R Granulocyte colony-stimulating factor receptor [113] 2.54[114] 5.16[115] 5.26[116] -3.30[117] -5.59[118] 3.72[119]
18 IL34 Interleukin-34 [120] 1.75[121] 2.05[122] -2.86[123] -0.29[124] -3.19[125] -1.02[126]
19 IL16 Pro-interleukin-16 [127] -0.86[128] -0.25[129] -2.13[130] 2.14[131] 2.00[132] 5.25[133]
20 PTPRZ1 Receptor-type tyrosine-protein phosphatase zeta [134] -4.30[135] [136] [137] -2.07[138] -1.78[139] 0.01[140]
21 SNAP25 Synaptosomal-associated protein 25 [141] -1.91[142] -1.42[143] 4.66[144] 4.92[145] 6.61[146] 2.30[147]
22 PRTN3 Myeloblastin [148] 2.34[149] [150] 6.72[151] 2.80[152] -0.39[153] 4.84[154]
23 IFNLR1 Interferon lambda receptor 1 [155] [156] [157] [158] [159] [160] [161]
24 IFNL1 Interferon lambda-1 [162] [163] [164] [165] [166] [167] [168]
[1]
ref_hepatocyte IL32
Mean 683
Standard deviation 7e+02
Values 5.6e+02 1.9e+03 4.6e+02 2.3e+02 2.5e+02
[2]
HepG2 IL32
Mean 203
Standard deviation 19
Values 2.2e+02 1.9e+02
[3]
HepG2.C3A IL32
Mean 115
Standard deviation 21
Values 1.3e+02 1e+02
[4]
HuH.7 IL32
Mean 9.4
Standard deviation 11
Values 2.7 22 3.6
[5]
SNU475 IL32
Mean 10.7
Standard deviation 1.6
Values 9.6 12
[6]
THLE IL32
Mean 5.68
Standard deviation 1.2
Values 4.8 6.5
[7]
liver IL32
Mean 49.5
Standard deviation 47
Values 34 13 1.2e+02 33
[8]
ref_hepatocyte SDC1
Mean 90.9
Standard deviation 70
Values 30 69 33 1.3e+02 1.9e+02
[9]
HepG2 SDC1
Mean 143
Standard deviation 14
Values 1.5e+02 1.3e+02
[10]
HepG2.C3A SDC1
Mean 92.1
Standard deviation 9.8
Values 85 99
[11]
HuH.7 SDC1
Mean 113
Standard deviation 31
Values 1.3e+02 77 1.3e+02
[12]
SNU475 SDC1
Mean 32.6
Standard deviation 5
Values 36 29
[13]
THLE SDC1
Mean 7.4
Standard deviation 0.31
Values 7.6 7.2
[14]
liver SDC1
Mean 222
Standard deviation 69
Values 1.8e+02 2.1e+02 3.2e+02 1.7e+02
[15]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 6.8 27 18 14 10
[16]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 40 56
[17]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 31 29
[18]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 36 32 29
[19]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 47 39
[20]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[21]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 54 75 58 62
[22]
ref_hepatocyte CD4
Mean 14.9
Standard deviation 25
Values 0.42 0 1.1 15 59
[23]
HepG2 CD4
Mean 0.611
Standard deviation 0.26
Values 0.42 0.8
[24]
HepG2.C3A CD4
Mean 2.47
Standard deviation 0.32
Values 2.2 2.7
[25]
HuH.7 CD4
Mean 0.383
Standard deviation 0.15
Values 0.28 0.55 0.32
[26]
SNU475 CD4
Mean 0.157
Standard deviation 0.028
Values 0.18 0.14
[27]
THLE CD4
Mean 0.0423
Standard deviation 0.0071
Values 0.047 0.037
[28]
liver CD4
Mean 20
Standard deviation 8
Values 22 15 30 13
[29]
ref_hepatocyte STX4
Mean 13.9
Standard deviation 5.2
Values 7.9 16 20 17 9.3
[30]
HepG2 STX4
Mean 13.6
Standard deviation 0.15
Values 14 13
[31]
HepG2.C3A STX4
Mean 13.1
Standard deviation 2.3
Values 15 11
[32]
HuH.7 STX4
Mean 12.8
Standard deviation 2.2
Values 13 11 15
[33]
SNU475 STX4
Mean 7.24
Standard deviation 0.6
Values 7.7 6.8
[34]
THLE STX4
Mean 9.72
Standard deviation 1.2
Values 8.9 11
[35]
liver STX4
Mean 4.49
Standard deviation 1.8
Values 6.4 2.8 5.7 3.1
[36]
ref_hepatocyte CASP3
Mean 12.5
Standard deviation 12
Values 33 13 6.8 4.9 5.1
[37]
HepG2 CASP3
Mean 30.3
Standard deviation 8.2
Values 25 36
[38]
HepG2.C3A CASP3
Mean 43.1
Standard deviation 22
Values 27 59
[39]
HuH.7 CASP3
Mean 7.08
Standard deviation 1
Values 5.9 7.5 7.8
[40]
SNU475 CASP3
Mean 12.3
Standard deviation 0.36
Values 13 12
[41]
THLE CASP3
Mean 27.6
Standard deviation 0.68
Values 27 28
[42]
liver CASP3
Mean 10.2
Standard deviation 4.2
Values 9.5 9 16 6.1
[43]
ref_hepatocyte STXBP2
Mean 11.5
Standard deviation 3.1
Values 11 7.1 15 14 10
[44]
HepG2 STXBP2
Mean 30.3
Standard deviation 4.3
Values 33 27
[45]
HepG2.C3A STXBP2
Mean 23.8
Standard deviation 7.2
Values 29 19
[46]
HuH.7 STXBP2
Mean 21.8
Standard deviation 4
Values 26 18 22
[47]
SNU475 STXBP2
Mean 9.07
Standard deviation 2.6
Values 11 7.2
[48]
THLE STXBP2
Mean 24
Standard deviation 0.74
Values 23 24
[49]
liver STXBP2
Mean 11
Standard deviation 6.5
Values 15 5.8 18 5.2
[50]
ref_hepatocyte TXLNA
Mean 9.32
Standard deviation 1.9
Values 6.8 11 10 11 7.7
[51]
HepG2 TXLNA
Mean 59.9
Standard deviation 5
Values 56 63
[52]
HepG2.C3A TXLNA
Mean 46.9
Standard deviation 6.3
Values 51 42
[53]
HuH.7 TXLNA
Mean 56.9
Standard deviation 15
Values 67 40 64
[54]
SNU475 TXLNA
Mean 35.9
Standard deviation 0.41
Values 36 36
[55]
THLE TXLNA
Mean 49.4
Standard deviation 5.8
Values 45 53
[56]
liver TXLNA
Mean 50.8
Standard deviation 14
Values 42 44 71 46
[57]
ref_hepatocyte IL10RB
Mean 8.5
Standard deviation 2.9
Values 6.8 6.7 5.7 12 11
[58]
HepG2 IL10RB
Mean 12.9
Standard deviation 0.15
Values 13 13
[59]
HepG2.C3A IL10RB
Mean 10.1
Standard deviation 0.73
Values 11 9.6
[60]
HuH.7 IL10RB
Mean 4.8
Standard deviation 0.49
Values 4.4 5.3 4.7
[61]
SNU475 IL10RB
Mean 13.5
Standard deviation 3.7
Values 16 11
[62]
THLE IL10RB
Mean 16.4
Standard deviation 0.029
Values 16 16
[63]
liver IL10RB
Mean 12.3
Standard deviation 5.1
Values 16 9.1 17 6.9
[64]
ref_hepatocyte VAMP2
Mean 7.38
Standard deviation 2
Values 9.9 5.1 8 8.2 5.7
[65]
HepG2 VAMP2
Mean 6.41
Standard deviation 1.5
Values 7.4 5.4
[66]
HepG2.C3A VAMP2
Mean 7.34
Standard deviation 3
Values 9.5 5.2
[67]
HuH.7 VAMP2
Mean 8.97
Standard deviation 0.78
Values 8.3 8.8 9.8
[68]
SNU475 VAMP2
Mean 9.81
Standard deviation 1.6
Values 11 8.7
[69]
THLE VAMP2
Mean 9.61
Standard deviation 0.14
Values 9.5 9.7
[70]
liver VAMP2
Mean 9.18
Standard deviation 10
Values 22 1 11 1.9
[71]
ref_hepatocyte CSF1
Mean 5.18
Standard deviation 6.2
Values 1 3.5 16 1.8 3.5
[72]
HepG2 CSF1
Mean 23.6
Standard deviation 5
Values 27 20
[73]
HepG2.C3A CSF1
Mean 0.803
Standard deviation 0.21
Values 0.65 0.95
[74]
HuH.7 CSF1
Mean 14
Standard deviation 1.7
Values 13 16 13
[75]
SNU475 CSF1
Mean 76.1
Standard deviation 3.8
Values 79 73
[76]
THLE CSF1
Mean 59.1
Standard deviation 0.34
Values 59 59
[77]
liver CSF1
Mean 9.8
Standard deviation 3.3
Values 11 5.2 13 10
[78]
ref_hepatocyte TYK2
Mean 4.82
Standard deviation 1.6
Values 2.6 4 5.2 6.8 5.6
[79]
HepG2 TYK2
Mean 23.5
Standard deviation 0.9
Values 23 24
[80]
HepG2.C3A TYK2
Mean 26.8
Standard deviation 2.6
Values 29 25
[81]
HuH.7 TYK2
Mean 28.1
Standard deviation 8.5
Values 35 19 31
[82]
SNU475 TYK2
Mean 14.9
Standard deviation 0.21
Values 15 15
[83]
THLE TYK2
Mean 31.6
Standard deviation 1.6
Values 33 31
[84]
liver TYK2
Mean 27.2
Standard deviation 3.5
Values 31 24 24 30
[85]
ref_hepatocyte STX3
Mean 2.84
Standard deviation 2.7
Values 7 3.6 2.5 0.74 0.29
[86]
HepG2 STX3
Mean 39.1
Standard deviation 2.9
Values 41 37
[87]
HepG2.C3A STX3
Mean 28.3
Standard deviation 2.6
Values 26 30
[88]
HuH.7 STX3
Mean 16.1
Standard deviation 6
Values 11 23 14
[89]
SNU475 STX3
Mean 12.4
Standard deviation 0.54
Values 13 12
[90]
THLE STX3
Mean 15.8
Standard deviation 2.8
Values 14 18
[91]
liver STX3
Mean 5.49
Standard deviation 1.2
Values 3.9 6.8 5.3 6
[92]
ref_hepatocyte CSF3
Mean 1.66
Standard deviation 3.7
Values 0 0 8.3 0 0
[93]
HepG2 CSF3
Mean 0.813
Standard deviation 0.63
Values 1.3 0.36
[94]
HepG2.C3A CSF3
Mean 0.0593
Standard deviation 0.054
Values 0.097 0.021
[95]
HuH.7 CSF3
Mean 0.0429
Standard deviation 0.021
Values 0.066 0.026 0.037
[96]
SNU475 CSF3
Mean 0.0247
Standard deviation 0.015
Values 0.014 0.035
[97]
THLE CSF3
Mean 74.8
Standard deviation 28
Values 95 55
[98]
liver CSF3
Mean 0.0138
Standard deviation 0.016
Values 0 0.029 0 0.026
[99]
ref_hepatocyte CSF1R
Mean 1.48
Standard deviation 1.9
Values 0 0.088 0.48 2.6 4.2
[100]
HepG2 CSF1R
Mean 0.0415
Standard deviation 0.047
Values 0.074 0.0086
[101]
HepG2.C3A CSF1R
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[102]
HuH.7 CSF1R
Mean 0.0119
Standard deviation 0.01
Values 0.016 0.019 0
[103]
SNU475 CSF1R
Mean 2.31
Standard deviation 1.6
Values 1.2 3.5
[104]
THLE CSF1R
Mean 0.105
Standard deviation 0.028
Values 0.12 0.085
[105]
liver CSF1R
Mean 13.6
Standard deviation 3.9
Values 8.8 15 13 18
[106]
ref_hepatocyte STX1A
Mean 0.672
Standard deviation 0.98
Values 0.23 0.39 2.4 0.095 0.24
[107]
HepG2 STX1A
Mean 2.85
Standard deviation 0.85
Values 3.4 2.2
[108]
HepG2.C3A STX1A
Mean 2.48
Standard deviation 0.71
Values 3 2
[109]
HuH.7 STX1A
Mean 0.845
Standard deviation 0.25
Values 0.57 0.91 1.1
[110]
SNU475 STX1A
Mean 7.45
Standard deviation 3.6
Values 4.9 10
[111]
THLE STX1A
Mean 4.19
Standard deviation 1.3
Values 5.1 3.3
[112]
liver STX1A
Mean 0.426
Standard deviation 0.18
Values 0.35 0.31 0.69 0.34
[113]
ref_hepatocyte CSF3R
Mean 0.568
Standard deviation 0.59
Values 1.2 0 0 0.49 1.1
[114]
HepG2 CSF3R
Mean 2.42
Standard deviation 0.98
Values 3.1 1.7
[115]
HepG2.C3A CSF3R
Mean 10.9
Standard deviation 8.2
Values 17 5.1
[116]
HuH.7 CSF3R
Mean 8.38
Standard deviation 2
Values 6.5 10 8.2
[117]
SNU475 CSF3R
Mean 0.0192
Standard deviation 0.0056
Values 0.023 0.015
[118]
THLE CSF3R
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[119]
liver CSF3R
Mean 4.44
Standard deviation 1.4
Values 3.5 3.1 5 6.2
[120]
ref_hepatocyte IL34
Mean 0.544
Standard deviation 0.74
Values 0.27 0 1.8 0.078 0.55
[121]
HepG2 IL34
Mean 1.34
Standard deviation 0.61
Values 1.8 0.91
[122]
HepG2.C3A IL34
Mean 1.21
Standard deviation 0.13
Values 1.3 1.1
[123]
HuH.7 IL34
Mean 0.0289
Standard deviation 0.032
Values 0.0082 0.013 0.066
[124]
SNU475 IL34
Mean 0.148
Standard deviation 0.0059
Values 0.14 0.15
[125]
THLE IL34
Mean 0.0284
Standard deviation 0.01
Values 0.035 0.021
[126]
liver IL34
Mean 0.159
Standard deviation 0.053
Values 0.19 0.086 0.21 0.16
[127]
ref_hepatocyte IL16
Mean 0.295
Standard deviation 0.38
Values 0 0 0.12 0.48 0.87
[128]
HepG2 IL16
Mean 0.119
Standard deviation 0.08
Values 0.063 0.18
[129]
HepG2.C3A IL16
Mean 0.133
Standard deviation 0.0092
Values 0.13 0.14
[130]
HuH.7 IL16
Mean 0.0259
Standard deviation 0.016
Values 0.0082 0.032 0.037
[131]
SNU475 IL16
Mean 0.431
Standard deviation 0.16
Values 0.32 0.55
[132]
THLE IL16
Mean 0.563
Standard deviation 0.066
Values 0.61 0.52
[133]
liver IL16
Mean 6.69
Standard deviation 2.9
Values 3.5 6.8 6 10
[134]
ref_hepatocyte PTPRZ1
Mean 0.154
Standard deviation 0.24
Values 0.042 0 0.57 0 0.15
[135]
HepG2 PTPRZ1
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[136]
HepG2.C3A PTPRZ1
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 PTPRZ1
Mean 0
Standard deviation 0
Values 0 0 0
[138]
SNU475 PTPRZ1
Mean 0.0122
Standard deviation 0.0042
Values 0.0093 0.015
[139]
THLE PTPRZ1
Mean 0.0213
Standard deviation 0.03
Values 0 0.043
[140]
liver PTPRZ1
Mean 0.092
Standard deviation 0.093
Values 0 0.16 0.026 0.19
[141]
ref_hepatocyte SNAP25
Mean 0.146
Standard deviation 0.17
Values 0 0 0.3 0.069 0.36
[142]
HepG2 SNAP25
Mean 0.0286
Standard deviation 0.032
Values 0.0057 0.051
[143]
HepG2.C3A SNAP25
Mean 0.0292
Standard deviation 0.041
Values 0.058 0
[144]
HuH.7 SNAP25
Mean 1.43
Standard deviation 0.14
Values 1.4 1.3 1.6
[145]
SNU475 SNAP25
Mean 1.47
Standard deviation 0.63
Values 1 1.9
[146]
THLE SNAP25
Mean 6.82
Standard deviation 0.47
Values 7.1 6.5
[147]
liver SNAP25
Mean 0.427
Standard deviation 0.11
Values 0.42 0.34 0.36 0.58
[148]
ref_hepatocyte PRTN3
Mean 0.0163
Standard deviation 0.036
Values 0 0 0 0 0.081
[149]
HepG2 PRTN3
Mean 0.0601
Standard deviation 0.037
Values 0.086 0.034
[150]
HepG2.C3A PRTN3
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 PRTN3
Mean 0.661
Standard deviation 0.24
Values 0.56 0.94 0.49
[152]
SNU475 PRTN3
Mean 0.0377
Standard deviation 0.032
Values 0.06 0.015
[153]
THLE PRTN3
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[154]
liver PRTN3
Mean 0.277
Standard deviation 0.29
Values 0.26 0.13 0.69 0.026
[155]
ref_hepatocyte IFNLR1
Missing
[156]
HepG2 IFNLR1
Mean 7.18
Standard deviation 0.62
Values 7.6 6.7
[157]
HepG2.C3A IFNLR1
Mean 19.6
Standard deviation 3.7
Values 22 17
[158]
HuH.7 IFNLR1
Mean 4.35
Standard deviation 0.97
Values 4.3 5.3 3.4
[159]
SNU475 IFNLR1
Mean 5.11
Standard deviation 0.16
Values 5.2 5
[160]
THLE IFNLR1
Mean 3.42
Standard deviation 0.35
Values 3.7 3.2
[161]
liver IFNLR1
Mean 6.63
Standard deviation 1.8
Values 4.8 9.1 5.9 6.7
[162]
ref_hepatocyte IFNL1
Missing
[163]
HepG2 IFNL1
Mean 0.0172
Standard deviation 0.024
Values 0.034 0
[164]
HepG2.C3A IFNL1
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[165]
HuH.7 IFNL1
Mean 0
Standard deviation 0
Values 0 0 0
[166]
SNU475 IFNL1
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[167]
THLE IFNL1
Mean 0
Standard deviation 0
Values 0 0
[168]
liver IFNL1
Mean 0.0128
Standard deviation 0.026
Values 0 0 0.051 0