REACTOME_NUCLEOTIDE_SALVAGE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APRT Adenine phosphoribosyltransferase [1] -0.57[2] -0.22[3] -0.40[4] -1.46[5] -0.85[6] -0.70[7]
2 TYMP Thymidine phosphorylase [8] -4.10[9] -3.38[10] -6.14[11] -7.83[12] -5.54[13] -1.19[14]
3 PNP Purine nucleoside phosphorylase [15] -0.14[16] -0.77[17] 0.06[18] -0.73[19] 0.44[20] -0.96[21]
4 ADK Adenosine kinase [22] -0.28[23] 0.84[24] -0.46[25] -0.92[26] -0.71[27] 1.30[28]
5 CDA Cytidine deaminase [29] -1.62[30] -3.13[31] -5.78[32] -3.84[33] -5.41[34] -1.24[35]
6 GMPR2 GMP reductase 2 [36] 1.49[37] 0.33[38] 1.44[39] -0.42[40] -0.06[41] -0.47[42]
7 DGUOK Deoxyguanosine kinase, mitochondrial [43] -0.22[44] -0.07[45] -0.14[46] -0.19[47] -0.48[48] -0.73[49]
8 HPRT1 Hypoxanthine-guanine phosphoribosyltransferase [50] -0.33[51] -0.01[52] 1.17[53] 1.11[54] 0.89[55] -0.84[56]
9 UPP1 Uridine phosphorylase 1 [57] -2.00[58] -1.94[59] -1.45[60] -0.65[61] 0.03[62] -1.20[63]
10 UCK1 Uridine-cytidine kinase 1 [64] -0.30[65] 0.66[66] 0.27[67] 0.39[68] 0.91[69] 1.18[70]
11 UCKL1 Uridine-cytidine kinase-like 1 [71] 1.46[72] 1.84[73] -0.08[74] 0.75[75] -0.18[76] 0.63[77]
12 DCK Deoxycytidine kinase [78] 0.08[79] 0.72[80] 0.10[81] 1.16[82] 1.45[83] -0.90[84]
13 TK1 Thymidine kinase, cytosolic [85] 2.41[86] 1.80[87] 1.60[88] 2.37[89] 2.32[90] -0.56[91]
14 AMPD2 AMP deaminase 2 [92] 1.85[93] 1.90[94] 2.70[95] 2.85[96] 1.88[97] 2.51[98]
15 UCK2 Uridine-cytidine kinase 2 [99] 1.95[100] 1.94[101] 2.18[102] 2.97[103] 2.72[104] 1.20[105]
16 TK2 Thymidine kinase 2, mitochondrial [106] 0.56[107] 1.12[108] 0.12[109] 1.43[110] 2.11[111] 3.10[112]
17 GMPR GMP reductase 1 [113] -6.20[114] [115] -8.84[116] 0.12[117] -0.16[118] -0.63[119]
18 ADA Adenosine deaminase [120] 1.66[121] 0.93[122] -0.90[123] 3.03[124] 0.27[125] -0.03[126]
19 ADAL Adenosine deaminase-like protein [127] 0.70[128] 1.44[129] 1.17[130] 2.16[131] 1.48[132] 1.29[133]
20 AMPD3 AMP deaminase 3 [134] 0.42[135] -1.20[136] 0.07[137] 2.52[138] 1.25[139] -0.25[140]
21 UPP2 Uridine phosphorylase 2 [141] -6.97[142] [143] -4.21[144] [145] -7.56[146] 2.37[147]
22 AMPD1 AMP deaminase 1 [148] [149] [150] -0.42[151] -0.74[152] -2.00[153] [154]
23 PUDP Pseudouridine-5'-phosphatase [155] [156] [157] [158] [159] [160] [161]
[1]
ref_hepatocyte APRT
Mean 64.6
Standard deviation 34
Values 20 41 82 1.1e+02 74
[2]
HepG2 APRT
Mean 67.9
Standard deviation 11
Values 76 60
[3]
HepG2.C3A APRT
Mean 71
Standard deviation 2.4
Values 69 73
[4]
HuH.7 APRT
Mean 52.3
Standard deviation 21
Values 62 29 66
[5]
SNU475 APRT
Mean 19.9
Standard deviation 1.6
Values 21 19
[6]
THLE APRT
Mean 39
Standard deviation 2.5
Values 37 41
[7]
liver APRT
Mean 28.4
Standard deviation 29
Values 52 3.4 55 4
[8]
ref_hepatocyte TYMP
Mean 63.3
Standard deviation 55
Values 1.8 1.5e+02 70 56 38
[9]
HepG2 TYMP
Mean 5.73
Standard deviation 3.7
Values 8.4 3.1
[10]
HepG2.C3A TYMP
Mean 7.77
Standard deviation 1.5
Values 8.9 6.7
[11]
HuH.7 TYMP
Mean 0.958
Standard deviation 0.51
Values 0.41 1.4 1
[12]
SNU475 TYMP
Mean 0.235
Standard deviation 0.14
Values 0.33 0.14
[13]
THLE TYMP
Mean 1.49
Standard deviation 0.28
Values 1.3 1.7
[14]
liver TYMP
Mean 19.9
Standard deviation 5.7
Values 17 19 15 28
[15]
ref_hepatocyte PNP
Mean 30
Standard deviation 33
Values 2.3 23 86 26 12
[16]
HepG2 PNP
Mean 42.3
Standard deviation 2.8
Values 44 40
[17]
HepG2.C3A PNP
Mean 22.5
Standard deviation 12
Values 14 31
[18]
HuH.7 PNP
Mean 33.5
Standard deviation 12
Values 31 23 46
[19]
SNU475 PNP
Mean 15.3
Standard deviation 6.3
Values 11 20
[20]
THLE PNP
Mean 44.5
Standard deviation 6.2
Values 40 49
[21]
liver PNP
Mean 11
Standard deviation 6
Values 20 6.1 8.7 9.7
[22]
ref_hepatocyte ADK
Mean 28
Standard deviation 12
Values 32 21 13 31 43
[23]
HepG2 ADK
Mean 35.9
Standard deviation 10
Values 29 43
[24]
HepG2.C3A ADK
Mean 64.3
Standard deviation 18
Values 52 77
[25]
HuH.7 ADK
Mean 21.8
Standard deviation 2.8
Values 21 19 25
[26]
SNU475 ADK
Mean 12.6
Standard deviation 1.1
Values 13 12
[27]
THLE ADK
Mean 18.7
Standard deviation 2.1
Values 17 20
[28]
liver ADK
Mean 49.4
Standard deviation 27
Values 83 26 60 29
[29]
ref_hepatocyte CDA
Mean 27.6
Standard deviation 20
Values 1.1 26 58 30 23
[30]
HepG2 CDA
Mean 14
Standard deviation 5.9
Values 18 9.9
[31]
HepG2.C3A CDA
Mean 4.04
Standard deviation 1.4
Values 5 3
[32]
HuH.7 CDA
Mean 0.54
Standard deviation 0.2
Values 0.49 0.76 0.37
[33]
SNU475 CDA
Mean 1.64
Standard deviation 0.19
Values 1.5 1.8
[34]
THLE CDA
Mean 0.708
Standard deviation 0.2
Values 0.85 0.57
[35]
liver CDA
Mean 8.36
Standard deviation 8.4
Values 16 1.1 15 1.2
[36]
ref_hepatocyte GMPR2
Mean 23.9
Standard deviation 12
Values 43 18 11 28 20
[37]
HepG2 GMPR2
Mean 104
Standard deviation 2.2
Values 1e+02 1.1e+02
[38]
HepG2.C3A GMPR2
Mean 38.3
Standard deviation 3.6
Values 41 36
[39]
HuH.7 GMPR2
Mean 69.4
Standard deviation 17
Values 58 89 62
[40]
SNU475 GMPR2
Mean 15.1
Standard deviation 3.5
Values 18 13
[41]
THLE GMPR2
Mean 25
Standard deviation 2.3
Values 23 27
[42]
liver GMPR2
Mean 12.4
Standard deviation 5.8
Values 20 8.8 15 6.6
[43]
ref_hepatocyte DGUOK
Mean 21.4
Standard deviation 7.8
Values 16 12 32 23 23
[44]
HepG2 DGUOK
Mean 28.6
Standard deviation 0.085
Values 29 29
[45]
HepG2.C3A DGUOK
Mean 26
Standard deviation 0.71
Values 26 25
[46]
HuH.7 DGUOK
Mean 20.7
Standard deviation 8.1
Values 20 13 29
[47]
SNU475 DGUOK
Mean 15.9
Standard deviation 2.3
Values 18 14
[48]
THLE DGUOK
Mean 16.8
Standard deviation 0.74
Values 16 17
[49]
liver DGUOK
Mean 9.23
Standard deviation 8.2
Values 17 2.1 15 2.2
[50]
ref_hepatocyte HPRT1
Mean 13.6
Standard deviation 5.4
Values 17 20 8.9 7.3 15
[51]
HepG2 HPRT1
Mean 16.9
Standard deviation 0.27
Values 17 17
[52]
HepG2.C3A HPRT1
Mean 17.3
Standard deviation 2.3
Values 16 19
[53]
HuH.7 HPRT1
Mean 32.8
Standard deviation 5.1
Values 32 28 38
[54]
SNU475 HPRT1
Mean 24.8
Standard deviation 3.3
Values 27 22
[55]
THLE HPRT1
Mean 27.5
Standard deviation 1.6
Values 26 29
[56]
liver HPRT1
Mean 5.44
Standard deviation 5.1
Values 7.1 1.6 12 1.1
[57]
ref_hepatocyte UPP1
Mean 12.8
Standard deviation 18
Values 0.33 9.2 44 7 3.2
[58]
HepG2 UPP1
Mean 4.99
Standard deviation 3.1
Values 7.2 2.8
[59]
HepG2.C3A UPP1
Mean 4.26
Standard deviation 0.42
Values 4 4.6
[60]
HuH.7 UPP1
Mean 4.99
Standard deviation 0.45
Values 4.9 4.6 5.5
[61]
SNU475 UPP1
Mean 6.88
Standard deviation 4.7
Values 3.6 10
[62]
THLE UPP1
Mean 14.3
Standard deviation 0.9
Values 14 15
[63]
liver UPP1
Mean 3.98
Standard deviation 3
Values 4.1 2.2 8.1 1.5
[64]
ref_hepatocyte UCK1
Mean 9.05
Standard deviation 4.7
Values 4.2 5.1 8.2 15 13
[65]
HepG2 UCK1
Mean 11.5
Standard deviation 1.6
Values 10 13
[66]
HepG2.C3A UCK1
Mean 18.3
Standard deviation 0.63
Values 18 19
[67]
HuH.7 UCK1
Mean 11.7
Standard deviation 1.2
Values 11 13 11
[68]
SNU475 UCK1
Mean 10
Standard deviation 0.3
Values 10 9.8
[69]
THLE UCK1
Mean 18.6
Standard deviation 4
Values 16 21
[70]
liver UCK1
Mean 14.7
Standard deviation 3.9
Values 19 12 17 11
[71]
ref_hepatocyte UCKL1
Mean 8.33
Standard deviation 4.8
Values 16 6 3.5 9.1 7
[72]
HepG2 UCKL1
Mean 35.7
Standard deviation 6
Values 40 32
[73]
HepG2.C3A UCKL1
Mean 38.1
Standard deviation 10
Values 45 31
[74]
HuH.7 UCKL1
Mean 8.47
Standard deviation 2
Values 7.2 7.4 11
[75]
SNU475 UCKL1
Mean 11.9
Standard deviation 4.2
Values 15 8.9
[76]
THLE UCKL1
Mean 8.02
Standard deviation 0.23
Values 8.2 7.9
[77]
liver UCKL1
Mean 9.25
Standard deviation 3.9
Values 14 5.6 10 6.9
[78]
ref_hepatocyte DCK
Mean 7.89
Standard deviation 10
Values 25 9.2 2.4 0.97 1.9
[79]
HepG2 DCK
Mean 13
Standard deviation 2.9
Values 11 15
[80]
HepG2.C3A DCK
Mean 16.6
Standard deviation 9.9
Values 9.6 24
[81]
HuH.7 DCK
Mean 9.05
Standard deviation 1.4
Values 9.5 7.5 10
[82]
SNU475 DCK
Mean 14.9
Standard deviation 1.6
Values 16 14
[83]
THLE DCK
Mean 23.6
Standard deviation 6
Values 19 28
[84]
liver DCK
Mean 3.03
Standard deviation 1.4
Values 3.4 2.1 4.9 1.7
[85]
ref_hepatocyte TK1
Mean 7.77
Standard deviation 6.2
Values 15 14 1 5.1 3.9
[86]
HepG2 TK1
Mean 64.4
Standard deviation 11
Values 57 72
[87]
HepG2.C3A TK1
Mean 34.6
Standard deviation 19
Values 21 48
[88]
HuH.7 TK1
Mean 25.2
Standard deviation 17
Values 32 5.8 38
[89]
SNU475 TK1
Mean 33.9
Standard deviation 0.54
Values 34 34
[90]
THLE TK1
Mean 42.5
Standard deviation 7.2
Values 37 48
[91]
liver TK1
Mean 3.78
Standard deviation 3.4
Values 4.3 1.8 8.3 0.65
[92]
ref_hepatocyte AMPD2
Mean 5.45
Standard deviation 3.1
Values 2.4 2.4 9.1 7.9 5.4
[93]
HepG2 AMPD2
Mean 30.7
Standard deviation 4.5
Values 27 34
[94]
HepG2.C3A AMPD2
Mean 26.1
Standard deviation 8.7
Values 32 20
[95]
HuH.7 AMPD2
Mean 38
Standard deviation 4.5
Values 40 33 42
[96]
SNU475 AMPD2
Mean 33.2
Standard deviation 4.7
Values 37 30
[97]
THLE AMPD2
Mean 22
Standard deviation 0.021
Values 22 22
[98]
liver AMPD2
Mean 22.3
Standard deviation 7.3
Values 28 12 24 26
[99]
ref_hepatocyte UCK2
Mean 5.1
Standard deviation 3.9
Values 3.5 9.5 9.2 2.1 1.2
[100]
HepG2 UCK2
Mean 30.7
Standard deviation 7.2
Values 36 26
[101]
HepG2.C3A UCK2
Mean 25.1
Standard deviation 0.56
Values 25 25
[102]
HuH.7 UCK2
Mean 24.8
Standard deviation 7.6
Values 29 16 30
[103]
SNU475 UCK2
Mean 33.8
Standard deviation 3
Values 32 36
[104]
THLE UCK2
Mean 36.6
Standard deviation 7.6
Values 31 42
[105]
liver UCK2
Mean 8.38
Standard deviation 1.3
Values 8.1 7.5 7.6 10
[106]
ref_hepatocyte TK2
Mean 4.07
Standard deviation 2.8
Values 1.9 2.1 2.1 6.5 7.7
[107]
HepG2 TK2
Mean 9.37
Standard deviation 2.7
Values 7.4 11
[108]
HepG2.C3A TK2
Mean 11.3
Standard deviation 0.3
Values 11 11
[109]
HuH.7 TK2
Mean 4.72
Standard deviation 0.87
Values 3.7 5.2 5.2
[110]
SNU475 TK2
Mean 9.29
Standard deviation 3.2
Values 12 7
[111]
THLE TK2
Mean 19.2
Standard deviation 0.11
Values 19 19
[112]
liver TK2
Mean 25
Standard deviation 6.3
Values 32 22 28 18
[113]
ref_hepatocyte GMPR
Mean 3.01
Standard deviation 4.1
Values 0 10 1.4 2 1.4
[114]
HepG2 GMPR
Mean 0.0637
Standard deviation 0.025
Values 0.046 0.082
[115]
HepG2.C3A GMPR
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 GMPR
Mean 0.00701
Standard deviation 0.0065
Values 0.0082 0.013 0
[117]
SNU475 GMPR
Mean 2.77
Standard deviation 0.62
Values 2.3 3.2
[118]
THLE GMPR
Mean 2.94
Standard deviation 0.057
Values 2.9 3
[119]
liver GMPR
Mean 1.39
Standard deviation 0.64
Values 1.3 1.2 2.3 0.77
[120]
ref_hepatocyte ADA
Mean 1.88
Standard deviation 0.53
Values 1.2 2.2 2.6 1.6 1.8
[121]
HepG2 ADA
Mean 9.29
Standard deviation 5.2
Values 13 5.6
[122]
HepG2.C3A ADA
Mean 4.58
Standard deviation 0.33
Values 4.3 4.8
[123]
HuH.7 ADA
Mean 1.08
Standard deviation 0.11
Values 1.1 1.1 0.96
[124]
SNU475 ADA
Mean 13
Standard deviation 2
Values 14 12
[125]
THLE ADA
Mean 2.48
Standard deviation 0.3
Values 2.7 2.3
[126]
liver ADA
Mean 1.32
Standard deviation 0.66
Values 1.9 0.81 1.9 0.69
[127]
ref_hepatocyte ADAL
Mean 1.78
Standard deviation 0.62
Values 2.2 2.5 0.91 1.8 1.5
[128]
HepG2 ADAL
Mean 4.52
Standard deviation 1.5
Values 3.5 5.6
[129]
HepG2.C3A ADAL
Mean 6.17
Standard deviation 0.39
Values 5.9 6.4
[130]
HuH.7 ADAL
Mean 4.3
Standard deviation 0.44
Values 4.7 3.8 4.3
[131]
SNU475 ADAL
Mean 6.74
Standard deviation 0.22
Values 6.9 6.6
[132]
THLE ADAL
Mean 5.43
Standard deviation 0.17
Values 5.5 5.3
[133]
liver ADAL
Mean 3.12
Standard deviation 0.44
Values 2.7 3.1 3.7 2.9
[134]
ref_hepatocyte AMPD3
Mean 1.56
Standard deviation 2.9
Values 0.089 0.55 6.7 0.32 0.13
[135]
HepG2 AMPD3
Mean 3.26
Standard deviation 0.92
Values 3.9 2.6
[136]
HepG2.C3A AMPD3
Mean 0.868
Standard deviation 0.18
Values 0.74 1
[137]
HuH.7 AMPD3
Mean 1.76
Standard deviation 0.87
Values 1.4 2.8 1.2
[138]
SNU475 AMPD3
Mean 7.59
Standard deviation 0.45
Values 7.3 7.9
[139]
THLE AMPD3
Mean 4.04
Standard deviation 0.56
Values 3.6 4.4
[140]
liver AMPD3
Mean 0.937
Standard deviation 0.39
Values 0.35 1.1 1.2 1.1
[141]
ref_hepatocyte UPP2
Mean 0.919
Standard deviation 1.8
Values 0 0 0.2 4.1 0.33
[142]
HepG2 UPP2
Mean 0.0114
Standard deviation 0.0081
Values 0.0057 0.017
[143]
HepG2.C3A UPP2
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 UPP2
Mean 0.053
Standard deviation 0.014
Values 0.057 0.064 0.037
[145]
SNU475 UPP2
Mean 0
Standard deviation 0
Values 0 0
[146]
THLE UPP2
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[147]
liver UPP2
Mean 3.41
Standard deviation 4.2
Values 9.7 1.8 1.5 0.62
[148]
ref_hepatocyte AMPD1
Mean 0.0195
Standard deviation 0.044
Values 0 0 0 0 0.098
[149]
HepG2 AMPD1
Mean 0
Standard deviation 0
Values 0 0
[150]
HepG2.C3A AMPD1
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 AMPD1
Mean 0.0156
Standard deviation 0.027
Values 0 0 0.047
[152]
SNU475 AMPD1
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[153]
THLE AMPD1
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[154]
liver AMPD1
Mean 0
Standard deviation 0
Values 0 0 0 0
[155]
ref_hepatocyte PUDP
Missing
[156]
HepG2 PUDP
Missing
[157]
HepG2.C3A PUDP
Missing
[158]
HuH.7 PUDP
Missing
[159]
SNU475 PUDP
Missing
[160]
THLE PUDP
Missing
[161]
liver PUDP
Missing